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    Ultra high molecular weight polyethylene for bearing surfaces
    3.
    发明授权
    Ultra high molecular weight polyethylene for bearing surfaces 有权
    用于轴承表面的超高分子量聚乙烯

    公开(公告)号：US08546460B2

    公开(公告)日：2013-10-01

    申请号：US12673266

    申请日：2008-09-04

    申请人： Lorenz Brunner ,  Yvo Dirix ,  Hans Schmotzer ,  Shilesh C. Jani

    发明人： Lorenz Brunner ,  Yvo Dirix ,  Hans Schmotzer ,  Shilesh C. Jani

    IPC分类号： C08F2/42 ,  C08F2/48 ,  C08J3/28 ,  A61F2/02

    CPC分类号： A61L27/26 ,  A61L27/50 ,  A61L27/54 ,  A61L2300/428

    摘要： A prosthetic device may comprise an insert having a first surface configured to contact a first prosthetic component and a bearing surface configured to articulate against a second prosthetic component. The insert comprises an ultra-high molecular weight polyethylene and vitamin E. The vitamin E may have a concentration in the range of 0.02 to 0.12 wt % first mixed with the ultra-high molecular weight polyethylene and then molded with the ultra-high molecular weight polyethylene at a temperature greater than the melting point of the ultra-high molecular weight polyethylene. The ultra-high molecular weight polyethylene and vitamin E may be gamma irradiated with a dosage of radiation between 5 and 20 Mrad. The insert may be machined prior to gamma irradiating the insert in air such that the gamma irradiation, at suitably high dosages, may also sterilize the insert.

    摘要翻译： 假体装置可以包括插入物，其具有构造成接触第一假体部件的第一表面和构造成与第二假体部件铰接的支承表面。 插入物包含超高分子量聚乙烯和维生素E.维生素E可以具有0.02至0.12重量％的浓度，首先与超高分子量聚乙烯混合，然后用超高分子量 聚乙烯，其温度大于超高分子量聚乙烯的熔点。 超高分子量聚乙烯和维生素E可以用5至20Mrad之间的辐射剂量照射γ射线。 在将伽马射线照射到空气中之前，可以对插入物进行加工，使得γ射线以合适的高剂量也可以对插入物进行消毒。

    OXIDATION RESISTANT HIGHLY-CROSSLINKED UHMWPE
    4.
    发明申请
    OXIDATION RESISTANT HIGHLY-CROSSLINKED UHMWPE 有权
    耐氧化高交联UHMWPE

    公开(公告)号：US20110116968A1

    公开(公告)日：2011-05-19

    申请号：US12992595

    申请日：2008-05-13

    申请人： Lorenz Brunner ,  Yvo Dirix ,  Hans Schmotzer

    发明人： Lorenz Brunner ,  Yvo Dirix ,  Hans Schmotzer

    IPC分类号： A61L2/08

    CPC分类号： C08K5/005 ,  C08J5/10 ,  C08L23/06 ,  C08L2666/02

    摘要： The present invention relates to highly cross-linked UHMWPE, which is possessed of an improved oxidation resistance, as well as a method for making the same. The UHMWPE material of the current invention is combined with an anti-oxidant compound or a free-radical scavenger prior to formation. Once the UHMWPE with the added material has been formed and treated with gamma or electron bean irradiation, it shows an improved wear resistance and also a good resistance to oxidation. Such a material, is particularly interesting for the field of making replacement joint implants.

    摘要翻译： 本发明涉及具有改善的抗氧化性的高度交联的UHMWPE及其制造方法。 本发明的UHMWPE材料在形成之前与抗氧化剂或自由基清除剂组合。 一旦用添加的材料形成UHMWPE并用γ射线或电子束照射进行处理，则其显示出改进的耐磨性和良好的耐氧化性。 这种材料对于替换关节植入物的领域尤其有意义。

    OXIDATION RESISTANT HIGHLY-CROSSLINKED UHMWPE
    5.
    发明申请
    OXIDATION RESISTANT HIGHLY-CROSSLINKED UHMWPE 审中-公开
    耐氧化高交联UHMWPE

    公开(公告)号：US20100144930A1

    公开(公告)日：2010-06-10

    申请号：US12531675

    申请日：2007-03-20

    申请人： Yvo Dirix ,  Hans Schmotzer ,  Lorenz Brunner

    发明人： Yvo Dirix ,  Hans Schmotzer ,  Lorenz Brunner

    IPC分类号： C08L23/06 ,  C08L97/00 ,  B65B55/02

    CPC分类号： C08J7/123 ,  C08F8/00 ,  C08F2810/20 ,  C08J3/203 ,  C08J3/28 ,  C08J2323/06 ,  C08K5/005 ,  C08L23/06 ,  C08F110/02

    摘要： The present invention relates to highly cross-linked UHMWPE, which is possessed of an improved oxidation resistance, as well as a method for making the same. The UHMWPE material of the current invention is combined with an anti-oxidant compound or a free-radical scavenger prior to formation. Once the UHMWPE with the added material has been formed and treated with gamma or electron beam irradiation, it shows an improved wear resistance and also a good resistance to oxidation. Such a material, is particularly interesting for the field of making replacement joint implants.

    摘要翻译： 本发明涉及具有改善的抗氧化性的高度交联的UHMWPE及其制造方法。 本发明的UHMWPE材料在形成之前与抗氧化剂或自由基清除剂组合。 一旦已经用γ或电子束照射形成并处理了具有添加材料的UHMWPE，则其显示出改进的耐磨性和良好的耐氧化性。 这种材料对于替换关节植入物的领域尤其有意义。

    Oxidation resistant highly-crosslinked UHMWPE
    6.
    发明授权
    Oxidation resistant highly-crosslinked UHMWPE 有权
    耐氧化高度交联的UHMWPE

    公开(公告)号：US08586667B2

    公开(公告)日：2013-11-19

    申请号：US12992595

    申请日：2008-05-13

    申请人： Lorenz Brunner ,  Yvo Dirix ,  Hans Schmotzer

    发明人： Lorenz Brunner ,  Yvo Dirix ,  Hans Schmotzer

    IPC分类号： C08L23/06 ,  C08G18/08

    CPC分类号： C08K5/005 ,  C08J5/10 ,  C08L23/06 ,  C08L2666/02

    摘要： The present invention relates to highly cross-linked UHMWPE, which is possessed of an improved oxidation resistance, as well as a method for making the same. The UHMWPE material of the current invention is combined with an anti-oxidant compound or a free-radical scavenger prior to formation. Once the UHMWPE with the added material has been formed and treated with gamma or electron bean irradiation, it shows an improved wear resistance and also a good resistance to oxidation. Such a material, is particularly interesting for the field of making replacement joint implants.

    摘要翻译： 本发明涉及具有改善的抗氧化性的高度交联的UHMWPE及其制造方法。 本发明的UHMWPE材料在形成之前与抗氧化剂或自由基清除剂组合。 一旦用添加的材料形成UHMWPE并用γ射线或电子束照射进行处理，则其显示出改进的耐磨性和良好的耐氧化性。 这种材料对于替换关节植入物的领域尤其有意义。

    ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE FOR BEARING SURFACES
    7.
    发明申请
    ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE FOR BEARING SURFACES 有权
    超高分子量聚对苯二甲酸乙二醇酯用于轴承表面

    公开(公告)号：US20110112646A1

    公开(公告)日：2011-05-12

    申请号：US12673266

    申请日：2008-09-04

    申请人： Lorenz Brunner ,  Yvo Dirix ,  Hans Schmotzer ,  Shilesh C. Jani

    发明人： Lorenz Brunner ,  Yvo Dirix ,  Hans Schmotzer ,  Shilesh C. Jani

    IPC分类号： A61F2/30 ,  B29C35/10

    CPC分类号： A61L27/26 ,  A61L27/50 ,  A61L27/54 ,  A61L2300/428

    摘要： A prosthetic device may comprise an insert having a first surface configured to contact a first prosthetic component and a bearing surface configured to articulate against a second prosthetic component. The insert comprises an ultra-high molecular weight polyethylene and vitamin E. The vitamin E may have a concentration in the range of 0.02 to 0.12 wt % first mixed with the ultra-high molecular weight polyethylene and then molded with the ultra-high molecular weight polyethylene at a temperature greater than the melting point of the ultra-high molecular weight polyethylene. The ultra-high molecular weight polyethylene and vitamin E may be gamma irradiated with a dosage of radiation between 5 and 20 Mrad. The insert may be machined prior to gamma irradiating the insert in air such that the gamma irradiation, at suitably high dosages, may also sterilize the insert.

    摘要翻译： 假体装置可以包括插入物，其具有构造成接触第一假体部件的第一表面和构造成与第二假体部件铰接的支承表面。 插入物包含超高分子量聚乙烯和维生素E.维生素E可以具有0.02至0.12重量％的浓度，首先与超高分子量聚乙烯混合，然后用超高分子量 聚乙烯，其温度大于超高分子量聚乙烯的熔点。 超高分子量聚乙烯和维生素E可以用5至20Mrad之间的辐射剂量照射γ射线。 在将伽马射线照射到空气中之前，可以对插入物进行加工，使得γ射线以合适的高剂量也可以对插入物进行消毒。

    COMPOSITIONS AND METHODS OF MAKING COMPOSITIONS
    9.
    发明申请
    COMPOSITIONS AND METHODS OF MAKING COMPOSITIONS 有权
    组合物和制备方法

    公开(公告)号：US20110180948A1

    公开(公告)日：2011-07-28

    申请号：US13003756

    申请日：2009-07-10

    申请人： Yvo Dirix ,  Lorenz Brunner ,  Jonathan Sander

    发明人： Yvo Dirix ,  Lorenz Brunner ,  Jonathan Sander

    IPC分类号： B29C44/04

    CPC分类号： C08J5/00 ,  A61L27/16 ,  A61L27/505 ,  C08K5/1545 ,  C08K9/10 ,  C08L23/06 ,  C08L2207/068

    摘要： A method for obtaining a composition of at least two components, comprising the steps of: providing at least one first fluid component; providing at least one second solid component and processing it so that the first component can diffuse into the second component; and diffusing the first component into the second component. A composition prepared by such a method.

    摘要翻译： 一种用于获得至少两种组分的组合物的方法，包括以下步骤：提供至少一种第一流体组分; 提供至少一个第二固体组分并加工，使得第一组分可以扩散到第二组分中; 并将第一组分扩散到第二组分中。 通过这种方法制备的组合物。