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    Ultra high molecular weight polyethylene for bearing surfaces
    1.
    发明授权
    Ultra high molecular weight polyethylene for bearing surfaces 有权
    用于轴承表面的超高分子量聚乙烯

    公开(公告)号：US08546460B2

    公开(公告)日：2013-10-01

    申请号：US12673266

    申请日：2008-09-04

    申请人： Lorenz Brunner ,  Yvo Dirix ,  Hans Schmotzer ,  Shilesh C. Jani

    发明人： Lorenz Brunner ,  Yvo Dirix ,  Hans Schmotzer ,  Shilesh C. Jani

    IPC分类号： C08F2/42 ,  C08F2/48 ,  C08J3/28 ,  A61F2/02

    CPC分类号： A61L27/26 ,  A61L27/50 ,  A61L27/54 ,  A61L2300/428

    摘要： A prosthetic device may comprise an insert having a first surface configured to contact a first prosthetic component and a bearing surface configured to articulate against a second prosthetic component. The insert comprises an ultra-high molecular weight polyethylene and vitamin E. The vitamin E may have a concentration in the range of 0.02 to 0.12 wt % first mixed with the ultra-high molecular weight polyethylene and then molded with the ultra-high molecular weight polyethylene at a temperature greater than the melting point of the ultra-high molecular weight polyethylene. The ultra-high molecular weight polyethylene and vitamin E may be gamma irradiated with a dosage of radiation between 5 and 20 Mrad. The insert may be machined prior to gamma irradiating the insert in air such that the gamma irradiation, at suitably high dosages, may also sterilize the insert.

    摘要翻译： 假体装置可以包括插入物，其具有构造成接触第一假体部件的第一表面和构造成与第二假体部件铰接的支承表面。 插入物包含超高分子量聚乙烯和维生素E.维生素E可以具有0.02至0.12重量％的浓度，首先与超高分子量聚乙烯混合，然后用超高分子量 聚乙烯，其温度大于超高分子量聚乙烯的熔点。 超高分子量聚乙烯和维生素E可以用5至20Mrad之间的辐射剂量照射γ射线。 在将伽马射线照射到空气中之前，可以对插入物进行加工，使得γ射线以合适的高剂量也可以对插入物进行消毒。

    ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE FOR BEARING SURFACES
    2.
    发明申请
    ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE FOR BEARING SURFACES 有权
    超高分子量聚对苯二甲酸乙二醇酯用于轴承表面

    公开(公告)号：US20110112646A1

    公开(公告)日：2011-05-12

    申请号：US12673266

    申请日：2008-09-04

    申请人： Lorenz Brunner ,  Yvo Dirix ,  Hans Schmotzer ,  Shilesh C. Jani

    发明人： Lorenz Brunner ,  Yvo Dirix ,  Hans Schmotzer ,  Shilesh C. Jani

    IPC分类号： A61F2/30 ,  B29C35/10

    CPC分类号： A61L27/26 ,  A61L27/50 ,  A61L27/54 ,  A61L2300/428

    摘要： A prosthetic device may comprise an insert having a first surface configured to contact a first prosthetic component and a bearing surface configured to articulate against a second prosthetic component. The insert comprises an ultra-high molecular weight polyethylene and vitamin E. The vitamin E may have a concentration in the range of 0.02 to 0.12 wt % first mixed with the ultra-high molecular weight polyethylene and then molded with the ultra-high molecular weight polyethylene at a temperature greater than the melting point of the ultra-high molecular weight polyethylene. The ultra-high molecular weight polyethylene and vitamin E may be gamma irradiated with a dosage of radiation between 5 and 20 Mrad. The insert may be machined prior to gamma irradiating the insert in air such that the gamma irradiation, at suitably high dosages, may also sterilize the insert.

    摘要翻译： 假体装置可以包括插入物，其具有构造成接触第一假体部件的第一表面和构造成与第二假体部件铰接的支承表面。 插入物包含超高分子量聚乙烯和维生素E.维生素E可以具有0.02至0.12重量％的浓度，首先与超高分子量聚乙烯混合，然后用超高分子量 聚乙烯，其温度大于超高分子量聚乙烯的熔点。 超高分子量聚乙烯和维生素E可以用5至20Mrad之间的辐射剂量照射γ射线。 在将伽马射线照射到空气中之前，可以对插入物进行加工，使得γ射线以合适的高剂量也可以对插入物进行消毒。

    METHOD OF PROVIDING A ZIRCONIUM SURFACE AND RESULTING PRODUCT
    8.
    发明申请
    METHOD OF PROVIDING A ZIRCONIUM SURFACE AND RESULTING PRODUCT 有权
    提供ZIRCONIUM表面和结果产品的方法

    公开(公告)号：US20110139312A1

    公开(公告)日：2011-06-16

    申请号：US12971933

    申请日：2010-12-17

    申请人： Gordon Hunter ,  Shilesh C. Jani ,  Vivek Pawar

    发明人： Gordon Hunter ,  Shilesh C. Jani ,  Vivek Pawar

    IPC分类号： B32B15/04 ,  C22C45/10

    CPC分类号： A61L27/306 ,  A61F2/30 ,  A61F2002/30024 ,  A61F2002/30026 ,  C22C45/10 ,  C23C8/02 ,  C23C8/10 ,  C23C30/00

    摘要： A coating of blue-black or black zirconium of uniform and controlled thickness on a zirconium or zirconium alloy material is accomplished through the treatment of an amorphous zirconium or zirconium alloy substrate, which may have an altered surface roughness. The treatment of amorphous zirconium or zirconium alloy substrates includes oxidation of the substrates. A zirconium coating of uniform and controlled thickness is especially useful in various applications because the uniformly thick zirconium surface of controlled depth provide a barrier against implant corrosion caused by ionization of the metal substrates.

    摘要翻译： 通过处理可能具有改变的表面粗糙度的无定形锆或锆合金基底来实现在锆或锆合金材料上具有均匀和受控厚度的蓝黑色或黑色锆的涂层。 无定形锆或锆合金基底的处理包括基底的氧化。 均匀和受控厚度的锆涂层在各种应用中特别有用，因为受控深度的均匀厚的锆表面提供了抵抗由金属基底的电离引起的植入物腐蚀的屏障。

    Cross-linked ultra-high molecular weight polyethylene for medical implant use
    10.
    发明授权
    Cross-linked ultra-high molecular weight polyethylene for medical implant use 有权
    用于医疗植入物使用的交联超高分子量聚乙烯

    公开(公告)号：US06709464B2

    公开(公告)日：2004-03-23

    申请号：US10271859

    申请日：2002-10-16

    申请人： Marcus L. Scott ,  Shilesh C. Jani

    发明人： Marcus L. Scott ,  Shilesh C. Jani

    IPC分类号： A61F234

    CPC分类号： A61L27/50 ,  A61L27/16 ,  C08L23/06 ,  C08L2312/06

    摘要： The present invention relates to the prevention and decrease of osteolysis produced by wear of the ultrahigh molecular weight polyethylene (UHMWPE). Methods are disclosed for the isolation of wear particles, preparation of implants exhibiting decreased wear in comparison to conventional UHMWPE and preparation of implants that cause decreased biological response in comparison to conventional UHMWPE. The implants created by these methods are also included in the present invention.

    摘要翻译： 本发明涉及通过超高分子量聚乙烯（UHMWPE）的磨损产生的骨质疏松的预防和减少。 公开了用于分离磨损颗粒的方法，与常规UHMWPE相比表现出降低的磨损的植入物的制备以及与常规UHMWPE相比引起生物反应降低的植入物的制备。 通过这些方法产生的植入物也包括在本发明中。