公开(公告)号：US5026642A

公开(公告)日：1991-06-25

申请号：US223051

申请日：1988-07-22

申请人： Hans-Eckart Radunz ,  Harry Schwartz ,  Martin Heinrich

发明人： Hans-Eckart Radunz ,  Harry Schwartz ,  Martin Heinrich

IPC分类号： C07C67/00 ,  C07C227/16 ,  C07C229/22 ,  C07C229/28 ,  C07C229/34 ,  C07C239/00 ,  C07C271/22 ,  C07D521/00 ,  C07K5/06 ,  C07K14/195 ,  C07K14/41 ,  C07K14/81 ,  C12P7/42 ,  C12P7/62 ,  C12P13/00 ,  C12P17/00 ,  C12P41/00

CPC分类号： C12P13/001 ,  C07C227/16 ,  C12P13/002 ,  C12P13/005 ,  C12P13/008 ,  C12P13/02 ,  C12P13/04 ,  C12P17/00 ,  C12P41/002 ,  C12P7/42 ,  C12P7/62 ,  Y10S435/93 ,  Y10S435/942

摘要： In a process for the reduction of ketones, the keto compounds are enantioselectively reduced to give secondary alcohols by means of microorganisms. Keto compounds of the formulaR.sup.3 NH--CHR.sup.1 --CO--CH.sub.2 --COOR.sup.2in which R.sup.1, R.sup.2 and R.sup.3 have the meanings defined herein are used as starting compounds.

摘要翻译： 在还原酮的方法中，酮化合物被对映选择性地还原以通过微生物产生仲醇。 其中R1，R2和R3具有本文定义的含义的式R3NH-CHR1-CO-CH2-COOR2的酮基化合物用作起始化合物。

公开(公告)号：US5294539A

公开(公告)日：1994-03-15

申请号：US781165

申请日：1991-10-16

申请人： Walther Johannssen ,  Harry Schwartz ,  Reiner Gromes ,  Martin Heinrich

发明人： Walther Johannssen ,  Harry Schwartz ,  Reiner Gromes ,  Martin Heinrich

IPC分类号： C12N9/02 ,  C12N9/96 ,  C12Q1/26 ,  C12R1/72 ,  C12Q1/12

CPC分类号： C12N9/0036 ,  C12N9/96 ,  C12Q1/26 ,  C12Y107/01002 ,  Y10S435/814 ,  Y10S435/921 ,  Y10S435/93

摘要： The invention relates to NAD(P)H-dependent nitrate reductase from yeasts, to a process for the preparation thereof and to the use thereof in a reagent for determining nitrate. The nitrate reductase is characterized by a molecular weight of about 350 000 D and can be obtained by yeast cells which have been cultivated in a completely synthetic nutrient medium with nitrate as the sole nitrogen source and which contain nitrate reductase being disrupted in phosphate buffer, the crude extract being chromatographed on an anion exchanger, the fractions containing nitrate reductase being mixed with protein, concentrated by ultrafiltration and dried by fluidized bed granulation. The reagent for determining nitrate contains, besides the nitrate reductase prepared in this way, also NAD(P)H and a color reagent for determining nitrite.

摘要翻译： PCT No.PCT / EP91 / 00199 Sec。 371日期1991年10月16日 102（e）日期1991年10月16日PCT 1991年2月2日PCT PCT。 公开号WO91 / 12319 日本1991年8月22日。本发明涉及来自酵母的NAD（P）H依赖性硝酸还原酶，涉及其制备方法及其在用于测定硝酸盐的试剂中的用途。 硝酸还原酶的特征在于分子量约为350000D，可以通过在硝酸盐作为唯一氮源并且含有硝酸还原酶在磷酸盐缓冲液中被破坏的完全合成营养培养基中培养的酵母细胞得到， 粗提物在阴离子交换剂上进行色谱分离，含有硝酸还原酶的级分与蛋白质混合，通过超滤浓缩并通过流化床造粒干燥。 用于测定硝酸盐的试剂除了以这种方式制备的硝酸盐还原酶之外，还含有NAD（P）H和用于测定亚硝酸盐的着色剂。

公开(公告)号：US20060219682A1

公开(公告)日：2006-10-05

申请号：US11286769

申请日：2005-11-23

申请人： Johannes Klett ,  Martin Heinrich

发明人： Johannes Klett ,  Martin Heinrich

IPC分类号： B23K9/06

CPC分类号： A61B18/1402 ,  A61B18/1206 ,  A61B2018/1213

摘要： The invention relates to a high-frequency surgical apparatus in which, for the purpose of cutting and/or coagulating biological tissue by means of high-frequency current, a high-frequency generator having a first electrode and a second electrode forms a high-frequency circuit through the tissue being treated, with an electric arc being formed, said apparatus having a measuring device to detect DC voltage components forming in the high frequency circuit when the arc is formed, said DC voltage components being usable for controlling the high-frequency generator via a controlling device. The invention is characterized in that the measuring device has an arc-decoupling circuit which separates the DC voltage components in the positive half-cycle of the high-frequency AC voltage from the DC voltage components in the negative half-cycle of the high-frequency AC voltage and makes available at least one of the separated DC voltage components as a signal for subsequent processing in the controlling device. The invention also relates to a corresponding method of running such apparatus.

摘要翻译： 本发明涉及一种高频手术装置，其中为了通过高频电流切割和/或凝结生物组织，具有第一电极和第二电极的高频发生器形成高频 电路通过正在处理的组织，形成电弧，所述装置具有测量装置，用于在电弧形成时检测在高频电路中形成的直流电压分量，所述直流电压分量可用于控制高频发生器 通过控制装置。 本发明的特征在于，测量装置具有电弧去耦电路，其将高频交流电压的正半周期中的直流电压分量与高频负的半周期中的直流电压分量分离 交流电压，并使分离的直流电压分量中的至少一个作为控制装置中后续处理的信号。 本发明还涉及运行这种装置的相应方法。

公开(公告)号：US07666182B2

公开(公告)日：2010-02-23

申请号：US11286769

申请日：2005-11-23

申请人： Johannes Klett ,  Martin Heinrich

发明人： Johannes Klett ,  Martin Heinrich

IPC分类号： A61B18/12

CPC分类号： A61B18/1402 ,  A61B18/1206 ,  A61B2018/1213

摘要： The invention relates to a high-frequency surgical apparatus in which, for the purpose of cutting and/or coagulating biological tissue by means of high-frequency current, a high-frequency generator having a first electrode and a second electrode forms a high-frequency circuit through the tissue being treated, with an electric arc being formed, said apparatus having a measuring device to detect DC voltage components forming in the high frequency circuit when the arc is formed, said DC voltage components being usable for controlling the high-frequency generator via a controlling device. The invention is characterized in that the measuring device has an arc-decoupling circuit which separates the DC voltage components in the positive half-cycle of the high-frequency AC voltage from the DC voltage components in the negative half-cycle of the high-frequency AC voltage and makes available at least one of the separated DC voltage components as a signal for subsequent processing in the controlling device. The invention also relates to a corresponding method of running such apparatus.

摘要翻译： 本发明涉及一种高频手术装置，其中为了通过高频电流切割和/或凝结生物组织，具有第一电极和第二电极的高频发生器形成高频 电路通过正在处理的组织，形成电弧，所述装置具有测量装置，用于在电弧形成时检测在高频电路中形成的直流电压分量，所述直流电压分量可用于控制高频发生器 通过控制装置。 本发明的特征在于，测量装置具有电弧去耦电路，其将高频交流电压的正半周期中的直流电压分量与高频负的半周期中的直流电压分量分离 交流电压，并使分离的直流电压分量中的至少一个作为控制装置中后续处理的信号。 本发明还涉及运行这种装置的相应方法。

公开(公告)号：US20140141374A1

公开(公告)日：2014-05-22

申请号：US13678625

申请日：2012-11-16

申请人： Celin Savariar-Hauck ,  Martin Heinrich

发明人： Celin Savariar-Hauck ,  Martin Heinrich

IPC分类号： G03F7/004

CPC分类号： G03F7/004 ,  B41C1/1008 ,  C09B23/0008 ,  C09B23/0066 ,  C09B23/08 ,  G03F7/029 ,  G03F7/105 ,  G03F7/3035

摘要： A negative-working lithographic printing plate precursor is used for making lithographic printing plates from infrared radiation imaging. The precursor comprises free radical chemistry and a specific infrared radiation absorber that is a cyanine dye and defined by Formula (1a) described in the disclosure. This particular infrared radiation absorber provides both IR sensitivity and print out after imaging.

摘要翻译： 使用负性平版印刷版原版从红外线成像制造平版印刷版。 前体包括自由基化学和特定的红外辐射吸收剂，其是花青染料并由本公开内容中描述的式（1a）限定。 这种特殊的红外线辐射吸收器既提供IR灵敏度又能在成像后打印出来。

公开(公告)号：US5196317A

公开(公告)日：1993-03-23

申请号：US608443

申请日：1990-11-02

申请人： Martin Heinrich ,  Wolfgang Ebeling ,  Wolfgang Brummer

发明人： Martin Heinrich ,  Wolfgang Ebeling ,  Wolfgang Brummer

IPC分类号： C12N9/00 ,  C12N1/21 ,  C12N9/04 ,  C12N15/09 ,  C12N15/53 ,  C12N15/67 ,  C12N15/73 ,  C12P21/00 ,  C12P21/02 ,  C12R1/19

CPC分类号： C12N9/0006 ,  C12N15/67 ,  C12N15/73

摘要： The invention relates to a process for achieving high, thermally-induced expression rates, which last for a relatively long period of time, of proteins in recombinant cells, preferably in E. coli cells, by optimizing cell density, induction temperature and supplemented amino-acid-containing substrates.

摘要翻译： 本发明涉及通过优化细胞密度，诱导温度和补充的氨基酸序列，实现重组细胞中，优选在大肠杆菌细胞中蛋白质持续相当长的时间的高的热诱导表达率的方法， 含酸底物。