摘要:
Pyrrolophenylalkanolamines of the formula ##STR1## R.sup.1 and R.sup.2 represent hydrogen or various radicals, R.sup.3 represents hydrogen, acyl or trialkylsilyl,R.sup.4 represents hydrogen or alkyl,R.sup.5 represents hydrogen, or, together with R.sup.3, represents ##STR2## wherein R.sup.7 represents hydrogen or alkyl, andR.sup.6 represents branched or cyfclic alkyl, which is optionally substituted,and salts thereof promote the yield of animals. Many new intermediates are also shown.
摘要:
A method for promoting production of useful livestock comprising administering to such livestock an amount effective therefor of a monosilylated aminopheylethylamine derivative of the formula ##STR1## in which X and Y are identical or different and represent hydrogen or CN,R.sup.2 represents hydrogen or methyl,R.sup.3 represents t-butyl, isopropyl, monofluoro-t-butyl or 1-cyclohexyl-ethyl, andR.sup.4, R.sup.5 and R.sup.6 denote a straight-chain or branched alkyl rdical,or a physiologically tolerated salt thereof.Those compounds wherein R.sup.3 is monofluoro-t-butyl or 1-cyclohexyl-ethyl are new, as is its intermediate ##STR2##
摘要:
Monosilylated aminophenylethylamine derivative of the formula ##STR1## in which X and Y each independently is hydrogen or halogen,R.sub.1 is the radical ##STR2## R.sub.2 is hydrogen or an aliphatic hydrocarbon radical having up to 10 C atoms,R.sub.3 is hydrogen, an aliphatic hydrocarbon radical which can optionally be substituted by halogen, a phenyl radical which can optionally be substituted by halogen, hydroxyl, alkyl, aryl, alkoxy, alkylthio, optionally substituted phenoxy, optionally substituted phenylthio, cyano or trifluoromethyl, or a heterocyclic radical, or, together with R.sub.2 is a nitrogen-containing saturated heterocyclic radical, andR.sub.4, R.sub.5 and R.sub.6 each independently is an alkyl radical,or physiologically tolerated salts thereof, promote the growth of animals.
摘要:
The invention relates to novel 3-imino-3-alkoxy-propionic acid lactates and their tautomeric acrylic acid lactates, processes for their preparation and their use as intermediates in the synthesis of 2-amino-substituted 1,4-dihydropyridines.
摘要:
The invention relates to novel, condensed 4-quinolyl-dhydropyridines of the general formula (I) ##STR1## in which A, R.sub.1, R.sub.2 and R.sub.3 have the meaning given in the description, to processes for their preparation and to their use in medicaments, in particular in agents for treating angiocardiopathies.
摘要:
Circulation-active fluoromethoxyphenyldihydropyridines of the formula ##STR1## in which X stands for hydrogen or fluorine andR stands for straight-chain, branched or cyclic alkyl or alkenyl having 2 to 12 carbon atoms which can be interrupted by 1 to 2 oxygen and/or sulphur atoms in the chain, and which can be monosubstituted or polysubstituted(a) by hydroxyl, aryl having 6 to 12 carbon atoms, aryloxy having 6 to 12 carbon atoms, where the aryl radical is again substituted by alkyl having up to 4 carbon atoms, alkoxy having up to 4 carbon atoms or halogen, the substituents being identical or different, or(b) by carboxyl, alkoxycarbonyl having up to 6 carbon atoms, pyridyl, piperidyl, pyrimidyl, acyloxy having up to 7 carbon atoms, sulphamoyl, carbamoyl, halogen or cyano, the substituents being identical or different, or(c) by an amino group, where the amino group can carry one or two identical or different substituents from the group consisting of alkyl having up to 6 carbon atoms, benzyl, phenyl or acyl having up to 7 carbon atoms,and salts thereof.
摘要:
Novel cardioactive compounds of the formula ##STR1## in which R.sup.1 is alkyl, aryl or heterocyclic, preferably substituted phenyl,R.sup.2 is alkyl, preferably methyl,R.sup.3 is hydrogen, halogen, acyloxy or alkyl, preferably hydrogen, andR.sup.4 is phenyl, carbalkoxy or together with R.sup.3 forms a ring, preferably carbalkoxy,are produced by reducing the corresponding nitro compounds.
摘要:
1,4-Dihydropyridines of the formula ##STR1## in which n is 0,1 or 2, andR.sup.1 to R.sup.7 can have a wide variety of meanings, which possess inotropic action, and many of which are new, are useful in increasing the influx of Ca.sup.++ into cells, particularly in combatting coronary and vascular diseases, hypertension swelling in the mucous membranes and diseases involving increased blood sugar or an incorrect salt and fluid balance.
摘要翻译:其中n为0,1或2,且R1至R7可以具有多种含义,其具有各向异性作用,并且其中许多是新的,可用于增加其中n为0,1或2的1,4-二氢吡啶 Ca ++进入细胞,特别是与冠状动脉和血管疾病的对抗,粘膜中的高血压肿胀和血糖升高或不正确的盐和液体平衡的疾病。