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1.发明申请Microfluidic device for electrochemically regulating pH of fluid therein and method of regulating pH of fluid using the microfluidic device 有权用于电化学调节流体pH值的微流体装置和使用微流体装置调节流体pH值的方法公开(公告)号：US20070017810A1
公开(公告)日：2007-01-25
申请号：US11489289
申请日：2006-07-19
申请人： Hun-joo Lee , Joon-ho Kim , Chin-sung Park , Young-sun Lee , Jong-Suk Chung
发明人： Hun-joo Lee , Joon-ho Kim , Chin-sung Park , Young-sun Lee , Jong-Suk Chung
IPC分类号： B01D61/44
CPC分类号： B01D67/0062 , B01D2311/2623
摘要： Provided is a microfluidic device for electrochemically regulating the pH of a fluid. The microfluidic device includes: an ion-exchange material; an anode chamber having a surface defined by a surface of the ion-exchange material and an anode electrode disposed along an edge of the surface of the anode chamber; and a cathode chamber having a surface defined by a surface of the ion-exchange material and a cathode electrode disposed along an edge of the surface of the cathode chamber, wherein the anode chamber and the cathode chamber are separated by an insulation material.
摘要翻译： 提供了用于电化学调节流体pH的微流体装置。 微流体装置包括：离子交换材料; 具有由所述离子交换材料的表面限定的表面的阳极室和沿着所述阳极室的表面的边缘设置的阳极电极; 以及阴极室，其具有由离子交换材料的表面限定的表面和沿着阴极室的表面的边缘设置的阴极电极，其中阳极室和阴极室由绝缘材料分隔开。
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2.发明授权Microfluidic device for electrochemically regulating pH of fluid therein and method of regulating pH of fluid using the microfluidic device 有权用于电化学调节流体pH值的微流体装置和使用微流体装置调节流体pH值的方法公开(公告)号：US07771573B2
公开(公告)日：2010-08-10
申请号：US11489289
申请日：2006-07-19
申请人： Hun-joo Lee , Joon-ho Kim , Chin-sung Park , Young-sun Lee , Jong-Suk Chung
发明人： Hun-joo Lee , Joon-ho Kim , Chin-sung Park , Young-sun Lee , Jong-Suk Chung
CPC分类号： B01D67/0062 , B01D2311/2623
摘要： Provided is a microfluidic device for electrochemically regulating the pH of a fluid. The microfluidic device includes: an ion-exchange material; an anode chamber having a surface defined by a surface of the ion-exchange material and an anode electrode disposed along an edge of the surface of the anode chamber; and a cathode chamber having a surface defined by a surface of the ion-exchange material and a cathode electrode disposed along an edge of the surface of the cathode chamber, wherein the anode chamber and the cathode chamber are separated by an insulation material.
摘要翻译： 提供了用于电化学调节流体pH的微流体装置。 微流体装置包括：离子交换材料; 具有由所述离子交换材料的表面限定的表面的阳极室和沿着所述阳极室的表面的边缘设置的阳极电极; 以及阴极室，其具有由离子交换材料的表面限定的表面和沿着阴极室的表面的边缘设置的阴极电极，其中阳极室和阴极室由绝缘材料分隔开。
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公开(公告)号：US08114261B2
公开(公告)日：2012-02-14
申请号：US11453538
申请日：2006-06-15
申请人： Hun-joo Lee , Joon-ho Kim , Chin-sung Park , Jung-im Han , Seung-yeon Yang , Shin-i Yoo
发明人： Hun-joo Lee , Joon-ho Kim , Chin-sung Park , Jung-im Han , Seung-yeon Yang , Shin-i Yoo
IPC分类号： B01D61/44
CPC分类号： B01L3/5027 , B01L2200/06
摘要： A microfluidic device for electrochemically regulating the pH of a fluid includes: an ion-exchange material; an anode chamber having a surface defined by a surface of the ion-exchange material and an anode electrode disposed along an edge of the surface of the anode chamber; and a cathode chamber having a surface defined by an opposite surface of the ion-exchange material and a cathode electrode disposed along an edge of the surface of the cathode chamber.
摘要翻译： 用于电化学调节流体pH的微流体装置包括：离子交换材料; 具有由所述离子交换材料的表面限定的表面的阳极室和沿着所述阳极室的表面的边缘设置的阳极电极; 以及阴极室，其具有由离子交换材料的相对表面限定的表面和沿着阴极室的表面的边缘设置的阴极电极。
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4.发明申请Microfluidic device for electrochemically regulating pH of fluid therein and method of regulating pH of fluid using the microfluidic device 有权用于电化学调节流体pH值的微流体装置和使用微流体装置调节流体pH值的方法公开(公告)号：US20070034504A1
公开(公告)日：2007-02-15
申请号：US11453538
申请日：2006-06-15
申请人： Hun-joo Lee , Joon-ho Kim , Chin-sung Park , Jung-im Han , Seung-yeon Yang , Shin-i Yoo
发明人： Hun-joo Lee , Joon-ho Kim , Chin-sung Park , Jung-im Han , Seung-yeon Yang , Shin-i Yoo
CPC分类号： B01L3/5027 , B01L2200/06
摘要： A microfluidic device for electrochemically regulating the pH of a fluid includes: an ion-exchange material; an anode chamber having a surface defined by a surface of the ion-exchange material and an anode electrode disposed along an edge of the surface of the anode chamber; and a cathode chamber having a surface defined by an opposite surface of the ion-exchange material and a cathode electrode disposed along an edge of the surface of the cathode chamber.
摘要翻译： 用于电化学调节流体pH的微流体装置包括：离子交换材料; 具有由所述离子交换材料的表面限定的表面的阳极室和沿着所述阳极室的表面的边缘设置的阳极电极; 以及阴极室，其具有由离子交换材料的相对表面限定的表面和沿着阴极室的表面的边缘设置的阴极电极。
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公开(公告)号：US08764956B2
公开(公告)日：2014-07-01
申请号：US13348168
申请日：2012-01-11
申请人： Hun-joo Lee , Joon-ho Kim , Chin-sung Park , Jung-im Han , Seung-yeon Yang , Shin-i Yoo
发明人： Hun-joo Lee , Joon-ho Kim , Chin-sung Park , Jung-im Han , Seung-yeon Yang , Shin-i Yoo
IPC分类号： B01L3/00
CPC分类号： B01L3/5027 , B01L2200/06
摘要： A microfluidic device for electrochemically regulating the pH of a fluid includes: an ion-exchange material; an anode chamber having a surface defined by a surface of the ion-exchange material and an anode electrode disposed along an edge of the surface of the anode chamber; and a cathode chamber having a surface defined by an opposite surface of the ion-exchange material and a cathode electrode disposed along an edge of the surface of the cathode chamber.
摘要翻译： 用于电化学调节流体pH的微流体装置包括：离子交换材料; 具有由所述离子交换材料的表面限定的表面的阳极室和沿着所述阳极室的表面的边缘设置的阳极电极; 以及阴极室，其具有由离子交换材料的相对表面限定的表面和沿着阴极室的表面的边缘设置的阴极电极。
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公开(公告)号：US08715965B2
公开(公告)日：2014-05-06
申请号：US11746722
申请日：2007-05-10
申请人： Hun-joo Lee , Sung-young Jeong , Joon-ho Kim , Kyu-youn Hwang
发明人： Hun-joo Lee , Sung-young Jeong , Joon-ho Kim , Kyu-youn Hwang
CPC分类号： B01D61/422 , B01D2325/20 , C12Q1/6806 , C12Q2565/629
摘要： A method of amplifying nucleic acid from blood, the method including performing an electrodialysis on a blood sample to reduce the ionic strength of the sample, and performing a Polymerase Chain Reaction (“PCR”) using the blood sample on which the electrodialysis is performed as a template.
摘要翻译： 一种从血液中扩增核酸的方法，所述方法包括对血液样品进行电渗析以降低样品的离子强度，并使用进行电渗析的血液样品进行聚合酶链式反应（“PCR”）， 一个模板
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7.发明授权Method of isolating nucleic acid using material positively charged at first pH and containing amino group and carboxyl group 有权使用在第一个pH下带正电并含有氨基和羧基的物质分离核酸的方法公开(公告)号：US07695678B2
公开(公告)日：2010-04-13
申请号：US12141894
申请日：2008-06-18
申请人： Kyu-youn Hwang , Joon-ho Kim , Chang-eun Yoo , Hun-joo Lee , Hee-kyun Lim , Sung-yung Jeong , Jeo-young Shim
发明人： Kyu-youn Hwang , Joon-ho Kim , Chang-eun Yoo , Hun-joo Lee , Hee-kyun Lim , Sung-yung Jeong , Jeo-young Shim
CPC分类号： C12N15/1006 , B01D15/361 , B01D15/364 , B01J20/3285 , B01J43/00 , C12Q1/6806 , C12Q2527/119 , C12Q2523/308
摘要： A method of isolating nucleic acid from a sample containing nucleic acid is provided. The method includes contacting the sample with a bifunctional material that contains an amino group and a carboxyl group and is positively charged at a first pH to allow binding of the nucleic acid to the bifunctional material; and extracting the nucleic acid at a second pH higher than the first pH from the complex.
摘要翻译： 提供了从含有核酸的样品中分离核酸的方法。 该方法包括使样品与含有氨基和羧基的双官能材料接触并在第一pH下带正电荷以允许核酸与双功能材料的结合; 以及从所述络合物中提取比所述第一pH高的第二pH的所述核酸。
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8.发明授权Method of isolating nucleic acid using material positively charged at first pH and containing amino group and carboxyl group 有权使用在第一个pH下带正电并含有氨基和羧基的物质分离核酸的方法公开(公告)号：US07402390B2
公开(公告)日：2008-07-22
申请号：US11317949
申请日：2005-12-23
申请人： Kyu-youn Hwang , Joon-ho Kim , Chang-eun Yoo , Hun-joo Lee , Hee-kyun Lim , Sung-young Jeong , Jeo-young Shim
发明人： Kyu-youn Hwang , Joon-ho Kim , Chang-eun Yoo , Hun-joo Lee , Hee-kyun Lim , Sung-young Jeong , Jeo-young Shim
CPC分类号： C12N15/1006 , B01D15/361 , B01D15/364 , B01J20/3285 , B01J43/00 , C12Q1/6806 , C12Q2527/119 , C12Q2523/308
摘要： A method of isolating nucleic acid from a sample containing nucleic acid is provided. The method includes contacting the sample with a bifunctional material that contains an amino group and a carboxyl group and is positively charged at a first pH to allow binding of the nucleic acid to the bifunctional material; and extracting the nucleic acid at a second pH higher than the first pH from the complex.
摘要翻译： 提供了从含有核酸的样品中分离核酸的方法。 该方法包括使样品与含有氨基和羧基的双官能材料接触并在第一pH下带正电荷以允许核酸与双功能材料的结合; 以及从所述络合物中提取比所述第一pH高的第二pH的所述核酸。
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9.发明申请METHOD AND DEVICE FOR SEPARATING CELLS FROM A SAMPLE USING A NONPLANAR SOLID SUBSTRATE 审中-公开使用非固体基质从样品分离细胞的方法和装置公开(公告)号：US20080044884A1
公开(公告)日：2008-02-21
申请号：US11841089
申请日：2007-08-20
申请人： Kyu-youn Hwang , Sung-young Jeong , Joon-ho Kim , Hun-joo Lee , Jung-im Han
发明人： Kyu-youn Hwang , Sung-young Jeong , Joon-ho Kim , Hun-joo Lee , Jung-im Han
CPC分类号： C12N15/1006 , B01L7/52 , B01L2300/0636 , C12N2533/30 , C12Q1/6806
摘要： Provided is a method and device for separating a cell from a sample. The method comprises contacting a nonplanar solid substrate with a cell-containing sample in a liquid medium having a pH of 3.0 to 6.0.
摘要翻译： 提供了用于从样品中分离细胞的方法和装置。 该方法包括使非平面固体基质与含有细胞的样品在pH为3.0至6.0的液体培养基中接触。
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公开(公告)号：US20070281307A1
公开(公告)日：2007-12-06
申请号：US11746722
申请日：2007-05-10
申请人： Hun-joo Lee , Sung-young Jeong , Joon-ho Kim , Kyu-youn Hwang
发明人： Hun-joo Lee , Sung-young Jeong , Joon-ho Kim , Kyu-youn Hwang
CPC分类号： B01D61/422 , B01D2325/20 , C12Q1/6806 , C12Q2565/629
摘要： A method of amplifying nucleic acid from blood, the method including performing an electrodialysis on a blood sample to reduce the ionic strength of the sample, and performing a Polymerase Chain Reaction (“PCR”) using the blood sample on which the electrodialysis is performed as a template.
摘要翻译： 一种从血液中扩增核酸的方法，所述方法包括对血液样品进行电渗析以降低样品的离子强度，并使用进行电渗析的血液样品进行聚合酶链式反应（“PCR”）， 一个模板
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