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公开(公告)号：US20140178933A1
公开(公告)日：2014-06-26
申请号：US14114886
申请日：2012-04-30
申请人： Hyun Min Koo , Byung Jo Yu , Ki Sung Lee , Jae Chan Park , Dae Hyuk Kweon , Sung Minm Park
发明人： Hyun Min Koo , Byung Jo Yu , Ki Sung Lee , Jae Chan Park , Dae Hyuk Kweon , Sung Minm Park
CPC分类号： C12N15/815 , C12P21/00 , C12P21/02
摘要： An expression vector which is capable of overexpressing a protein of interest in a host cell, a host cell comprising the expression vector, and a method of producing a protein of interest are provided.
摘要翻译： 提供了能够在宿主细胞中过表达目的蛋白质的表达载体，包含表达载体的宿主细胞和产生目的蛋白质的方法。
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2.发明授权Vector and microorganism for increasing galactose catabolism and methods therefor 失效载体和微生物用于增加半乳糖分解代谢及其方法公开(公告)号：US08722388B2
公开(公告)日：2014-05-13
申请号：US12481193
申请日：2009-06-09
申请人： Byung Jo Yu , Jae Chan Park , Hyun Min Koo , Yong Su Jin , Ki Sung Lee
发明人： Byung Jo Yu , Jae Chan Park , Hyun Min Koo , Yong Su Jin , Ki Sung Lee
CPC分类号： C12N15/1034 , C07K14/395 , C12P7/04 , C12P7/06 , C12P7/16 , C12P7/28 , Y02E50/10 , Y02E50/17
摘要： Provided herein are a recombinant vector and microorganism including the isolated SNR84 gene, and a method of increasing volumetric productivity of biofuel from a galactose-containing carbon source using the isolated SNR84 gene, the recombinant vector or the recombinant microorganism. Also disclosed herein is a method of screening yeast for genes associated with increased galactose catabolism when the genes are overexpressed.
摘要翻译： 本文提供了包含分离的SNR84基因的重组载体和微生物，以及使用分离的SNR84基因，重组载体或重组微生物从含半乳糖的碳源增加生物燃料的体积生产率的方法。 本文还公开了当基因过表达时筛选与增加的半乳糖分解代谢相关的基因的酵母的方法。
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公开(公告)号：US08541212B2
公开(公告)日：2013-09-24
申请号：US13368953
申请日：2012-02-08
申请人： Jae Young Kim , Jae Chan Park , Sung Min Park , Hyun Min Koo , Byung Jo Yu , Hwa Young Cho , Young kyoung Park
发明人： Jae Young Kim , Jae Chan Park , Sung Min Park , Hyun Min Koo , Byung Jo Yu , Hwa Young Cho , Young kyoung Park
IPC分类号： C12P7/62
CPC分类号： C12P7/42 , C12N9/0006 , C12N9/1029 , C12Y101/01001 , C12Y101/01027 , C12Y203/01008
摘要： A method of increasing 3-HP production efficiency by inhibiting expression of a lactate dehydrogenase, a phosphotransacetylase, and an alcohol dehydrogenase in production of 3-HP using a malonic semialdehyde reduction pathway to prevent metabolite leak and increase a malonyl-CoA pool is disclosed.
摘要翻译： 公开了一种通过抑制乳酸脱氢酶，磷酸转乙酰酶和醇脱氢酶在产生3-HP中的表达而使用丙二醛半醛还原途径来预防代谢物泄漏并增加丙二酰辅酶A池的3-HP生产效率的方法。
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4.发明授权Compositions and methods for measuring 3,6-L-AHG transferase activity and 3,6-L-AHG 有权用于测量3,6-L-AHG转移酶活性的组合物和方法以及3,6-L-AHG公开(公告)号：US08486654B2
公开(公告)日：2013-07-16
申请号：US13034387
申请日：2011-02-24
申请人： Hyun Min Koo , Sung Min Park , Jae Chan Park , Kyoung Heon Kim , In Geol Choi
发明人： Hyun Min Koo , Sung Min Park , Jae Chan Park , Kyoung Heon Kim , In Geol Choi
IPC分类号： G01N33/573
CPC分类号： C12Q1/48 , C12N9/1051 , G01N2333/91102
摘要： Provided herein are a composition for measuring 3,6-anhydro-L-galactose (3,6-L-AHG) transferase activity by reduction of NADP to NADPH, and a method of measuring 3,6-L-AHG transferase activity using the same. The composition and method are useful for determining 3,6-L-AHG in a material containing 3,6-L-AHG such as algae biomass and industrial applications.
摘要翻译： 本文提供了通过将NADP还原成NADPH来测量3,6-脱水-L-半乳糖（3,6-L-AHG）转移酶活性的组合物，以及使用以下方法测量3,6-L-AHG转移酶活性的方法 相同。 该组合物和方法可用于测定含有3,6-L-AHG的材料中的3,6-L-AHG，例如藻类生物质和工业应用。
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5.发明授权Isolated polypeptide for increasing activity of polysaccharide hydrolase and methods of use 有权用于增加多糖水解酶活性的分离多肽和使用方法公开(公告)号：US08492126B2
公开(公告)日：2013-07-23
申请号：US12874670
申请日：2010-09-02
申请人： Hwa Young Cho , Hyun Min Koo , Jae Chan Park , Sung Min Park , In Geol Choi , Kyoung Heon Kim
发明人： Hwa Young Cho , Hyun Min Koo , Jae Chan Park , Sung Min Park , In Geol Choi , Kyoung Heon Kim
CPC分类号： C12P7/10 , C07K14/195 , C07K14/32 , C07K14/37 , C12N9/2437 , C12N9/248 , C12P19/02 , C12P19/14 , Y02E50/16 , Y02E50/343
摘要： An isolated polypeptide is disclosed that improves the hydrolyzing capacity of a polysaccharide hydrolase such as cellulase, is capable of binding to a polysaccharide, is deficient in polysaccharide hydrolase activity, and includes a GH45 or a pollen-allergen domain. Methods of hydrolyzing polysaccharides using the isolated polypeptide are also disclosed.
摘要翻译： 公开了提高多糖水解酶如纤维素酶的水解能力的分离多肽，其能够结合多糖，缺乏多糖水解酶活性，并且包括GH45或花粉 - 变应原结构域。 还公开了使用分离的多肽水解多糖的方法。
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公开(公告)号：US09150835B2
公开(公告)日：2015-10-06
申请号：US13531356
申请日：2012-06-22
申请人： Soon Chun Chung , Hyun Min Koo , Jae Young Kim , Ji Eun Kim , Jin Woo Kim , Young kyoung Park , So Young Lee , Hwa Young Cho , Dae Huck Kweon , Jae Chan Park
发明人： Soon Chun Chung , Hyun Min Koo , Jae Young Kim , Ji Eun Kim , Jin Woo Kim , Young kyoung Park , So Young Lee , Hwa Young Cho , Dae Huck Kweon , Jae Chan Park
CPC分类号： C12N9/0006 , C12N15/81 , C12N15/815 , C12P7/56 , C12Y101/01027
摘要： A modified microorganism for high efficient production of lactic acid, an expression vector for constructing the modified microorganism, and a method of producing a lactic acid using the same are disclosed. The modified microorganism may produce lactic acid at a high level under acid conditions.
摘要翻译： 公开了一种用于高效生产乳酸的改性微生物，用于构建修饰微生物的表达载体和使用其的乳酸生产方法。 改性微生物可在酸性条件下高水平生产乳酸。
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公开(公告)号：US20100047900A1
公开(公告)日：2010-02-25
申请号：US11794688
申请日：2005-12-30
申请人： Young Hoon Park , Hyun Min Koo , Jun Ok Moon , Seong Jun Kim , Hyo Jin Kim , Jung Kee Lee
发明人： Young Hoon Park , Hyun Min Koo , Jun Ok Moon , Seong Jun Kim , Hyo Jin Kim , Jung Kee Lee
CPC分类号： C07K14/34
摘要： Disclosed is a novel L-lysine-inducible promoter nucleic acid molecule. Also disclosed are a vector containing the nucleic acid molecule, a host cell transformed with the vector, and a method of inducing expression of a target gene using the L-lysine-inducible promoter nucleic acid molecule.
摘要翻译： 公开了一种新的L-赖氨酸诱导型启动子核酸分子。 还公开了含有核酸分子，用载体转化的宿主细胞的载体和使用L-赖氨酸诱导型启动子核酸分子诱导靶基因表达的方法。
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公开(公告)号：US07851198B2
公开(公告)日：2010-12-14
申请号：US11794688
申请日：2005-12-30
申请人： Young Hoon Park , Hyun Min Koo , Jun Ok Moon , Seong Jun Kim , Hyo Jin Kim , Jung Kee Lee
发明人： Young Hoon Park , Hyun Min Koo , Jun Ok Moon , Seong Jun Kim , Hyo Jin Kim , Jung Kee Lee
CPC分类号： C07K14/34
摘要： Disclosed is a novel L-lysine-inducible promoter nucleic acid molecule. Also disclosed are a vector containing the nucleic acid molecule, a host cell transformed with the vector, and a method of inducing expression of a target gene using the L-lysine-inducible promoter nucleic acid molecule.
摘要翻译： 公开了一种新的L-赖氨酸诱导型启动子核酸分子。 还公开了含有核酸分子，用载体转化的宿主细胞的载体和使用L-赖氨酸诱导型启动子核酸分子诱导靶基因表达的方法。
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9.发明授权Microorganism of corynebacterium genus having enhanced L-lysine production ability and method of producing L-lysine using the same 有权具有增强的L-赖氨酸生产能力的棒状杆菌属的微生物和使用其产生L-赖氨酸的方法公开(公告)号：US07794990B2
公开(公告)日：2010-09-14
申请号：US11564599
申请日：2006-11-29
申请人： Young Hoon Park , Hyun Min Koo , Sang Jo Lim , Jun Ok Moon , So Yeon Rah , Young Lyeol Yang
发明人： Young Hoon Park , Hyun Min Koo , Sang Jo Lim , Jun Ok Moon , So Yeon Rah , Young Lyeol Yang
CPC分类号： C12R1/15 , C12N9/1205 , C12N9/88 , C12P13/08
摘要： Provided are a microorganism of Corynebacterium genus that has an inactivated endogenous NCgl1835 gene therein and produces L-lysine, and a method of producing L-lysine using the same.
摘要翻译： 本发明提供一种具有失活的内源性NCgl1835基因并产生L-赖氨酸的棒状杆菌属的微生物，以及使用该微生物的L-赖氨酸的方法。
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10.发明授权Microorganism of the genus Corynebacterium having enhanced L-lysine productivity and method of producing L-lysine using the microorganism of the genus Corynebacterium 有权具有增强的L-赖氨酸生产力的棒状杆菌属的微生物和使用棒状杆菌属微生物生产L-赖氨酸的方法公开(公告)号：US07575899B2
公开(公告)日：2009-08-18
申请号：US11562176
申请日：2006-11-21
申请人： Young Hoon Park , Hyun Min Koo , Sang Jo Lim , Jun Ok Moon , Young Lyeol Yang
发明人： Young Hoon Park , Hyun Min Koo , Sang Jo Lim , Jun Ok Moon , Young Lyeol Yang
IPC分类号： C12P21/04
CPC分类号： C12R1/15 , C12N9/0004 , C12P13/08
摘要： The present invention provides a microorganism that belongs to the genus Corynebacterium and has an inactivated inherent NCgl2053 dehydrogenase gene, and a method of producing L-lysine using the same. By using the microorganism, the yield of L-lysine is increased since an inherent NCgl2053 dehydrogenase gene is inactivated. According to the method, L-lysine can be produced with high yield.
摘要翻译： 本发明提供属于棒杆菌属的具有灭活的固有的NCgl2053脱氢酶基因的微生物及使用其的L-赖氨酸的制造方法。 通过使用微生物，L-赖氨酸的产量增加，因为固有的NCgl2053脱氢酶基因被灭活。 根据该方法，可以高产率制备L-赖氨酸。
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