-
公开(公告)号：US11680292B2
公开(公告)日：2023-06-20
申请号：US17840569
申请日：2022-06-14
发明人： Jeffrey S. Fisher , Brian D. Mather , Maria Candelaria Rogert Bacigalupo , Justin Fullerton , Ludovic Vincent , Lewis J. Kraft , Sahngki Hong , Boyan Boyanov , M. Shane Bowen , Sang Park , Wayne N. George , Andrew A. Brown
IPC分类号： C12Q1/6869 , C08F220/56 , C08G77/04 , G03F7/075 , G03F7/16 , G03F7/00 , G03F7/004
CPC分类号： C12Q1/6869 , C08F220/56 , C08G77/04 , G03F7/0757 , G03F7/165 , G03F7/0002 , G03F7/0046
摘要： An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.
-
公开(公告)号：US20230002822A1
公开(公告)日：2023-01-05
申请号：US17840569
申请日：2022-06-14
发明人： Jeffrey S. Fisher , Brian D. Mather , Maria Candelaria Rogert Bacigalupo , Justin Fullerton , Ludovic Vincent , Lewis J. Kraft , Sahngki Hong , Boyan Boyanov , M. Shane Bowen , Sang Park , Wayne N. George , Andrew A. Brown
IPC分类号： C12Q1/6869 , C08F220/56 , C08G77/04 , G03F7/075 , G03F7/16
摘要： An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.
-
公开(公告)号：US11512339B2
公开(公告)日：2022-11-29
申请号：US15848640
申请日：2017-12-20
发明人： Wayne N. George , Alexandre Richez , M. Shane Bowen , Andrew A. Brown , Dajun Yuan , Audrey Rose Zak , Sean M. Ramirez , Raymond Campos
IPC分类号： C09D183/06 , C12Q1/68 , C09D133/26 , C08G77/14
摘要： An example of an array includes a support, a cross-linked epoxy polyhedral oligomeric silsesquioxane (POSS) resin film on a surface of the support, and a patterned hydrophobic polymer layer on the cross-linked epoxy POSS resin film. The patterned hydrophobic polymer layer defines exposed discrete areas of the cross-linked epoxy POSS resin film, and a polymer coating is attached to the exposed discrete areas. Another example of an array includes a support, a modified epoxy POSS resin film on a surface of the support, and a patterned hydrophobic polymer layer on the modified epoxy POSS resin film. The modified epoxy POSS resin film includes a polymer growth initiation site, and the patterned hydrophobic polymer layer defines exposed discrete areas of the modified epoxy POSS resin film. A polymer brush is attached to the polymer growth initiation site in the exposed discrete areas.
-
公开(公告)号：US11124829B2
公开(公告)日：2021-09-21
申请号：US16626452
申请日：2019-06-07
发明人： Jeffrey S. Fisher , Brian D. Mather , Maria Candelaria Rogert Bacigalupo , Justin Fullerton , Ludovic Vincent , Lewis J. Kraft , Sahngki Hong , Boyan Boyanov , M. Shane Bowen , Sang Park , Wayne N. George , Andrew A. Brown , Dajun Yuan
IPC分类号： C12Q1/68 , G03F7/16 , C12Q1/6869 , C08F220/56 , C08G77/04 , G03F7/075 , G03F7/00 , G03F7/004
摘要： An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.
-
公开(公告)号：US20210139975A1
公开(公告)日：2021-05-13
申请号：US17139834
申请日：2020-12-31
发明人： Jeffrey S. Fisher , Brian D. Mather , Maria Candelaria Rogert Bacigalupo , Justin Fullerton , Ludovic Vincent , Lewis J. Kraft , Sahngki Hong , Boyan Boyanov , M. Shane Bowen , Sang Park , Wayne N. George , Andrew A. Brown , Dajun Yuan
IPC分类号： C12Q1/6869 , C08F220/56 , C08G77/04 , G03F7/075 , G03F7/16
摘要： An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.
-
公开(公告)号：US10901230B2
公开(公告)日：2021-01-26
申请号：US16311652
申请日：2017-06-20
发明人： Gary Mark Skinner , Geraint Wyn Evans , Stanley S. Hong , John A. Moon , M. Shane Bowen , Jonathan Mark Boutell , Jason Richard Betley
摘要： Example super-resolution microscopy systems are described herein that are configured for relatively high throughput. The disclosed microscopy systems can be to generate an array of sub-diffraction activated areas for imaging. The microscopy systems can be to utilize imaging techniques that employ time delay integration to build up super-resolution images over time. The disclosed microscopy systems can utilize long-lived fluorophores in conjunction with wide field and patterned illumination to generate super-resolution images of a sample with relatively high throughput.
-
公开(公告)号：US11988957B2
公开(公告)日：2024-05-21
申请号：US18317865
申请日：2023-05-15
发明人： Jeffrey S. Fisher , Brian D. Mather , Maria Candelaria Rogert Bacigalupo , Justin Fullerton , Ludovic Vincent , Lewis J. Kraft , Sahngki Hong , Boyan Boyanov , M. Shane Bowen , Sang Park , Wayne N. George , Andrew A. Brown
IPC分类号： G03F7/00 , C08F220/56 , C08G77/04 , C12Q1/6869 , G03F7/075 , G03F7/16 , G03F7/004
CPC分类号： G03F7/0002 , C08F220/56 , C08G77/04 , C12Q1/6869 , G03F7/0757 , G03F7/165 , G03F7/0046
摘要： An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.
-
公开(公告)号：US11938475B2
公开(公告)日：2024-03-26
申请号：US17114134
申请日：2020-12-07
发明人： Hongji Ren , Jonathan Mark Boutell , John A. Moon , M. Shane Bowen , Alex Nemiroski , Gary Mark Skinner , Kenny Chen
IPC分类号： B01L3/00 , B01J19/00 , C08F220/56 , C08F220/60 , C09D133/26 , C12Q1/6876
CPC分类号： B01L3/502 , B01J19/0046 , C08F220/56 , C08F220/603 , C09D133/26 , C12Q1/6876 , B01J2219/00475 , B01J2219/00729 , B01L2200/12 , B01L2300/0893 , B01L2300/16
摘要： In an example of the method, a functionalized coating layer is applied in depressions of a patterned flow cell substrate. The depressions are separated by interstitial regions. A primer is grafted to the functionalized coating layer to form a grafted functionalized coating layer in the depressions. A hydrogel is applied on at least the grafted functionalized coating layer.
-
公开(公告)号：US11932900B2
公开(公告)日：2024-03-19
申请号：US17973327
申请日：2022-10-25
发明人： Wayne N. George , Alexandre Richez , M. Shane Bowen , Andrew A. Brown , Dajun Yuan , Audrey Rose Zak , Sean M. Ramirez , Raymond Campos
IPC分类号： C08J7/04 , C09D133/26 , C09D183/06 , C12Q1/68 , C08G77/14
CPC分类号： C12Q1/68 , C09D133/26 , C09D183/06 , C08G77/14
摘要： An example of an array includes a support, a cross-linked epoxy polyhedral oligomeric silsesquioxane (POSS) resin film on a surface of the support, and a patterned hydrophobic polymer layer on the cross-linked epoxy POSS resin film. The patterned hydrophobic polymer layer defines exposed discrete areas of the cross-linked epoxy POSS resin film, and a polymer coating is attached to the exposed discrete areas. Another example of an array includes a support, a modified epoxy POSS resin film on a surface of the support, and a patterned hydrophobic polymer layer on the modified epoxy POSS resin film. The modified epoxy POSS resin film includes a polymer growth initiation site, and the patterned hydrophobic polymer layer defines exposed discrete areas of the modified epoxy POSS resin film. A polymer brush is attached to the polymer growth initiation site in the exposed discrete areas.
-
公开(公告)号：US11384392B2
公开(公告)日：2022-07-12
申请号：US17139834
申请日：2020-12-31
发明人： Jeffrey S. Fisher , Brian D. Mather , Maria Candelaria Rogert Bacigalupo , Justin Fullerton , Ludovic Vincent , Lewis J. Kraft , Sahngki Hong , Boyan Boyanov , M. Shane Bowen , Sang Park , Wayne N. George , Andrew A. Brown
IPC分类号： C12Q1/6869 , C08F220/56 , C08G77/04 , G03F7/075 , G03F7/16 , G03F7/00 , G03F7/004
摘要： An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.
-
-
-
-
-
-
-
-
-
搜索结果
122 条记录 (耗时 0.026 秒)
