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公开(公告)号：US20200377756A1
公开(公告)日：2020-12-03
申请号：US16771285
申请日：2018-12-11
发明人： Kristin Taton , Daniel Guire , Nathaniel Olson , Eric Guire , Patrick Guire
IPC分类号： C09D175/02 , C09D5/16 , C08G18/75 , C08G18/73 , C08G18/66 , C08G18/50 , C08G18/32 , A61B5/00 , B05D1/02 , B05D1/18
摘要： Durable polyurea copolymer coatings can be applied to surfaces that come in contact with fluids, such as biological fluids, thereby passivating the surface. Polyurea copolymer coating compositions comprise a reaction product of (a) a diamine composition that includes a polyethylene glycol diamine, and optionally, a dipiperidyl alkane; and (b) a diisocyanate. Solutions containing polyurea copolymers, coated surfaces and methods are also described.
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公开(公告)号：US10266620B2
公开(公告)日：2019-04-23
申请号：US15370410
申请日：2016-12-06
发明人： Jie Wen , Kristin Taton , Laurie Lawin , William Knopke , Eric Guire , Patrick Guire
IPC分类号： C09D137/00 , C08F8/42 , C08F8/30 , C09D131/00 , A61L31/02 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/00 , B05D3/06 , A61L29/06 , A61L29/08 , A61L29/14 , A61L29/16 , C08F8/28 , C08F267/04 , C09D135/00
摘要： The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied. The coating agents are useful for providing a coating that can be further functionalized (for example, by application of additional coating layers), or for providing desirable properties to a surface.
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公开(公告)号：US20160251646A1
公开(公告)日：2016-09-01
申请号：US15028709
申请日：2014-10-11
发明人： Eric Guire , Christopher Bahr
CPC分类号： C12N11/08 , C12M25/14 , C12M41/46 , C12N5/0068 , C12N2533/30
摘要： Inventive concepts relate generally to nanofibrous scaffolds useful for electrophysiological assays. Scaffolds include polymeric nanofibrous components and electrically excitable cells immobilized at a distinct cell seeding domains on the scaffold. Methods and kits including the scaffolds are also described.
摘要翻译： 发明概念通常涉及可用于电生理测定的纳米纤维支架。 支架包括聚合物纳米纤维组分和固定在支架上不同细胞接种结构域的电可激发细胞。 还描述了包括支架的方法和试剂盒。
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公开(公告)号：US09539371B2
公开(公告)日：2017-01-10
申请号：US14749815
申请日：2015-06-25
发明人： Jie Wen , Kristin Taton , Laurie Lawin , William Knopke , Eric Guire , Patrick Guire
IPC分类号： C09D137/00 , A61L31/10 , C08F8/30 , C08F8/42 , C09D131/00 , A61L31/02 , A61L31/06 , A61L31/14 , A61L31/16 , A61L33/00 , B05D3/06
CPC分类号： C08F8/42 , A61L29/06 , A61L29/085 , A61L29/14 , A61L29/16 , A61L31/022 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/0005 , A61L2300/404 , A61L2300/42 , A61L2400/10 , A61L2420/02 , A61L2420/08 , B05D3/06 , C08F8/28 , C08F8/30 , C08F267/04 , C09D131/00 , C09D135/00 , Y10T428/31507 , Y10T428/31511 , Y10T428/31573 , Y10T428/31598 , Y10T428/31663 , Y10T428/31667 , Y10T428/31721 , Y10T428/3175 , Y10T428/31797 , Y10T428/31855 , Y10T428/31884 , Y10T428/31909 , Y10T428/31913 , Y10T428/31928 , C08F222/06
摘要： The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied.
摘要翻译： 本发明描述了新颖的涂层剂，其包括聚合物，一个或多个潜在反应性基团和一个或多个非共价连接基团，所选择的非共价连接基团与施加涂覆剂的基底相互作用。
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公开(公告)号：US20150359944A1
公开(公告)日：2015-12-17
申请号：US14749815
申请日：2015-06-25
发明人： Jie Wen , Kristin Taton , Laurie Lawin , William Knopke , Eric Guire , Patrick Guire
CPC分类号： C08F8/42 , A61L29/06 , A61L29/085 , A61L29/14 , A61L29/16 , A61L31/022 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/0005 , A61L2300/404 , A61L2300/42 , A61L2400/10 , A61L2420/02 , A61L2420/08 , B05D3/06 , C08F8/28 , C08F8/30 , C08F267/04 , C09D131/00 , C09D135/00 , Y10T428/31507 , Y10T428/31511 , Y10T428/31573 , Y10T428/31598 , Y10T428/31663 , Y10T428/31667 , Y10T428/31721 , Y10T428/3175 , Y10T428/31797 , Y10T428/31855 , Y10T428/31884 , Y10T428/31909 , Y10T428/31913 , Y10T428/31928 , C08F222/06
摘要： The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied. The coating agents are useful for providing a coating that can be further functionalized (for example, by
摘要翻译： 本发明描述了新颖的涂层剂，其包括聚合物，一个或多个潜在反应性基团和一个或多个非共价连接基团，所选择的非共价连接基团与施加涂覆剂的基底相互作用。 涂层剂可用于提供可以进一步官能化的涂层（例如，
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公开(公告)号：US11407977B2
公开(公告)日：2022-08-09
申请号：US16684560
申请日：2019-11-14
发明人： Eric Guire , Christopher Bahr
IPC分类号： C12N5/00 , C12M1/12 , C12N11/089 , C12N11/096 , C12M1/34
摘要： Inventive concepts relate generally to nanofibrous scaffolds useful for electrophysiological assays. Scaffolds include polymeric nanofibrous components and electrically excitable cells immobilized at a distinct cell seeding domains on the scaffold. Methods and kits including the scaffolds are also described.
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公开(公告)号：US20200095570A1
公开(公告)日：2020-03-26
申请号：US16684560
申请日：2019-11-14
发明人： Eric Guire , Christopher Bahr
摘要： Inventive concepts relate generally to nanofibrous scaffolds useful for electrophysiological assays. Scaffolds include polymeric nanofibrous components and electrically excitable cells immobilized at a distinct cell seeding domains on the scaffold. Methods and kits including the scaffolds are also described.
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公开(公告)号：US20170081435A1
公开(公告)日：2017-03-23
申请号：US15370410
申请日：2016-12-06
发明人： Jie Wen , Kristin Taton , Laurie Lawin , William Knopke , Eric Guire , Patrick Guire
IPC分类号： C08F8/42 , A61L29/08 , A61L29/06 , C08F8/28 , B05D3/06 , A61L31/06 , A61L29/14 , C08F267/04 , A61L29/16 , A61L31/16 , C09D135/00 , A61L31/10
CPC分类号： C08F8/42 , A61L29/06 , A61L29/085 , A61L29/14 , A61L29/16 , A61L31/022 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/0005 , A61L2300/404 , A61L2300/42 , A61L2400/10 , A61L2420/02 , A61L2420/08 , B05D3/06 , C08F8/28 , C08F8/30 , C08F267/04 , C09D131/00 , C09D135/00 , Y10T428/31507 , Y10T428/31511 , Y10T428/31573 , Y10T428/31598 , Y10T428/31663 , Y10T428/31667 , Y10T428/31721 , Y10T428/3175 , Y10T428/31797 , Y10T428/31855 , Y10T428/31884 , Y10T428/31909 , Y10T428/31913 , Y10T428/31928 , C08F222/06
摘要： The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied. The coating agents are useful for providing a coating that can be further functionalized (for example, by application of additional coating layers), or for providing desirable properties to a surface.
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