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公开(公告)号:US11929177B2
公开(公告)日:2024-03-12
申请号:US17224746
申请日:2021-04-07
发明人: Qinghuang Lin , Jeffrey L. Rogers , Giovanni Russo , Andrea Simonetto , Tigran Tigran Tchrakian
摘要: Techniques regarding pain treatment are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can include: a data collection component that can determine at least one parameter associated with a pain perception of a subject, a computing component that can determine a relationship between the pain perception and the at least one parameter using artificial intelligence, and can determine a treatment for the subject based on the relationship; and a treatment component that can cause a device associated with the subject to apply at least a portion of the treatment.
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公开(公告)号:US11754550B2
公开(公告)日:2023-09-12
申请号:US16045987
申请日:2018-07-26
IPC分类号: G01N33/487 , B01L3/00 , C12Q1/00
CPC分类号: G01N33/48735 , B01L3/502715 , C12Q1/001 , G01N33/48785 , G01N33/48792 , B01L2300/023 , B01L2300/0645 , B01L2300/123
摘要: In an approach, a biomedical device comprises at least one electrode, wherein the at least one electrode is coupled with a computer chip; at least two chemical sensors, wherein the at least two chemical sensors are coupled with the computer chip; the computer chip, wherein the computer chip comprises: a semiconductor substrate, and a processor; a microfluidic structure, wherein the microfluidic structure is an inert elastomeric polymer; a power supply device coupled to the computer chip; and an antenna configured to send data collected onto the computer chip to a remote server. In an approach, a processor stimulating a cell sample. A processor senses the presence of at least two types of biomolecules released by the cell sample. A processor records data collected by the at least two chemical sensors. A processor sends the recorded data to a remote server.
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公开(公告)号:US20210225514A1
公开(公告)日:2021-07-22
申请号:US17224746
申请日:2021-04-07
发明人: Qinghuang Lin , Jeffrey L. Rogers , Giovanni Russo , Andrea Simonetto , Tigran Tigran Tchrakian
摘要: Techniques regarding pain treatment are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can include: a data collection component that can determine at least one parameter associated with a pain perception of a subject, a computing component that can determine a relationship between the pain perception and the at least one parameter using artificial intelligence, and can determine a treatment for the subject based on the relationship; and a treatment component that can cause a device associated with the subject to apply at least a portion of the treatment.
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公开(公告)号:US11013908B2
公开(公告)日:2021-05-25
申请号:US16691993
申请日:2019-11-22
摘要: A nanodevice includes an array of metal nanorods formed on a substrate. An electropolymerized electrical conductor is formed over tops of a portion of the nanorods to form a reservoir between the electropolymerized conductor and the substrate. The electropolymerized conductor includes pores that open or close responsively to electrical signals applied to the nanorods. A cell loading region is disposed in proximity of the reservoir, and the cell loading region is configured to receive stem cells. A neurotrophic dispensing material is loaded in the reservoir to be dispersed in accordance with open pores to affect growth of the stem cells when in vivo.
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公开(公告)号:US10954544B2
公开(公告)日:2021-03-23
申请号:US16691737
申请日:2019-11-22
IPC分类号: C12Q1/00 , G01N27/327 , G01N33/94
摘要: Embodiments of the present invention are directed to a semiconductor device. A non-limiting example of the semiconductor device includes a semiconductor substrate. The semiconductor device also includes a plurality of metal nanopillars formed on the substrate. The semiconductor device also includes an amperometric sensor associated with one of the plurality of nanopillars, wherein the amperometric sensor is selective to an enzyme-active neurotransmitter. The semiconductor device also includes a resistivity sensor associated with a pair of nanopillars, wherein the resistivity sensor is selective to an analyte.
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公开(公告)号:US10926079B2
公开(公告)日:2021-02-23
申请号:US16573533
申请日:2019-09-17
摘要: A nanodevice includes an array of metal nanorods formed on a substrate. An electropolymerized electrical conductor is formed over tops of a portion of the nanorods to form a reservoir between the electropolymerized conductor and the substrate. The electropolymerized conductor includes pores that open or close responsively to electrical signals applied to the nanorods. A cell loading region is disposed in proximity of the reservoir, and the cell loading region is configured to receive stem cells. A neurotrophic dispensing material is loaded in the reservoir to be dispersed in accordance with open pores to affect growth of the stem cells when in vivo.
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公开(公告)号:US20200219765A1
公开(公告)日:2020-07-09
申请号:US16238925
申请日:2019-01-03
发明人: Shyng-Tsong Chen , Qinghuang Lin
IPC分类号: H01L21/768 , H01L23/532
摘要: A process for manufacturing interconnect BEOL structures from a patternable low-k dielectric on a microcircuit substrate having an optional anti-reflective coating comprises applying to the microcircuit substrate a via coating for forming a via comprising a low-k patternable dielectric coating, exposing the via coating to a via pattern, developing the exposed via coating, curing the exposed and developed via coating to form a via film, applying a trench coating for forming a trench comprising a patternable low-k dielectric coating, exposing the trench coating to a trench pattern, developing the exposed and developed trench coating, followed by curing the trench coating to form a trench film; Curing one of the uncured coatings to form a film prevents it from inter-mixing with the other applied uncured coating. Articles of manufacture comprise products made by this process as well as dual-damascene integrated spun-on patterned low-k dielectrics, and single-damascene integrated spun-on patterned low-k dielectrics.
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公开(公告)号:US10573687B2
公开(公告)日:2020-02-25
申请号:US15798816
申请日:2017-10-31
发明人: Qinghuang Lin
摘要: A method of forming a device that includes encapsulating a magnetic resistive access memory (MRAM) stack with a first patternable low-k dielectric material that is patterned by a exposure to produce a via pattern that extends to circuitry to logic devices. The via pattern is developed forming a via opening. The method further includes forming a second patternable low-k dielectric material over first patternable low-k dielectric material and filling the via opening. The second patternable low-k dielectric material is patterned by a light exposure to produce a first line pattern to the MRAM stack and a second line pattern to the via opening. The first line pattern and the second line pattern are developed to form trench openings. Thereafter, electrically conductive material is formed in the trench openings and the via opening.
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公开(公告)号:US10464061B2
公开(公告)日:2019-11-05
申请号:US15096933
申请日:2016-04-12
发明人: Jingwei Bai , Qinghuang Lin , Gustavo A. Stolovitzky , Chao Wang , Deqiang Wang
IPC分类号: B81C1/00 , B01L3/00 , C12Q1/6869 , G01N33/487 , C12Q1/6874 , B82Y40/00
摘要: A technique includes forming a gradient channel with width and depth gradients. A mask is disposed on top of a substrate. The mask is patterned with at least one elongated channel pattern having different elongated channel pattern widths. A channel is etched in the substrate in a single etching step, the channel having a width gradient and a corresponding depth gradient both simultaneously etched in the single etching step according to the different elongated channel pattern widths in the mask.
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公开(公告)号:US20180339154A1
公开(公告)日:2018-11-29
申请号:US15602343
申请日:2017-05-23
发明人: Hariklia Deligianni , Bruce B. Doris , Steven J. Holmes , Emily R. Kinser , Qinghuang Lin , Roy R. Yu
IPC分类号: A61N1/36 , H01L21/3213 , H01L21/283 , H01L23/58 , A61N1/05 , A61B5/145 , A61B5/00 , A61B5/06
摘要: A sensing and treatment device includes an array of metal nanorod electrodes formed on a substrate, the array including first electrodes for sensing, and second electrodes for electrical pulsation. A data processing system is configured to monitor a parameter using the first electrodes and to activate the electrical pulsation in the second electrodes in accordance with a reading of the parameter.
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