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    Method and apparatus for analyte processing
    3.
    发明授权
    Method and apparatus for analyte processing 有权
    用于分析物处理的方法和装置

    公开(公告)号：US08961902B2

    公开(公告)日：2015-02-24

    申请号：US12175037

    申请日：2008-07-17

    申请人： Peter W. Falb ,  David Brancazio ,  Eric France ,  Brett P. Masters ,  Michael F. Miller ,  Joshua R. Ormsby ,  Walker Sloan

    发明人： Peter W. Falb ,  David Brancazio ,  Eric France ,  Brett P. Masters ,  Michael F. Miller ,  Joshua R. Ormsby ,  Walker Sloan

    IPC分类号： B01L3/00 ,  G01N35/00

    CPC分类号： G01N35/00029 ,  B01L3/5025 ,  B01L3/502715 ,  B01L3/502738 ,  B01L2200/025 ,  B01L2200/16 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2400/0487 ,  B01L2400/0655 ,  G01N2035/00148 ,  Y10T29/49

    摘要： A system for processing analytes in samples includes an instrument and a cartridge. The cartridge includes fluid inputs, input and output valve assemblies, processing devices, fluid reservoirs, and channels for carrying samples from the fluid inputs to the fluid reservoirs. The valve assemblies include valves adapted to form a sealed fluid chamber in response to force applied by a movable head assembly of the instrument. Each fluid reservoir is adapted to mate and align with an air displacement pump interface member. A valve assembly includes a recess wall surrounding a recess and a valve assembly wall surrounding both the recess and the recess wall. The recess wall and the valve assembly walls are adapted to mate with and seal against a flexible sheet covering the recess, the recess wall, and the valve assembly wall. The cartridge and instrument include complementary features for finely and coarsely aligning instrument assemblies with portions of the cartridge.

    摘要翻译： 用于处理样品中分析物的系统包括仪器和墨盒。 墨盒包括流体输入，输入和输出阀组件，处理装置，流体储存器和用于将样品从流体输入传送到流体储存器的通道。 阀组件包括适于响应由仪器的可移动头组件施加的力而形成密封流体室的阀。 每个流体储存器适于与排气泵接口构件配合和对准。 阀组件包括围绕凹部的凹陷壁和围绕凹部和凹陷壁的阀组件壁。 凹陷壁和阀组件壁适于与覆盖凹部，凹陷壁和阀组件壁的柔性薄片配合并密封。 墨盒和仪器包括用于精细和粗略地对准具有部分墨盒的仪器组件的互补特征。

    Resonant sensor systems and methods with reduced gas interference
    6.
    发明授权
    Resonant sensor systems and methods with reduced gas interference 有权
    谐振传感器系统和减少气体干扰的方法

    公开(公告)号：US08475715B2

    公开(公告)日：2013-07-02

    申请号：US11502168

    申请日：2006-08-10

    申请人： Brett P. Masters ,  Michael F. Miller

    发明人： Brett P. Masters ,  Michael F. Miller

    IPC分类号： G01N27/00

    CPC分类号： G01N29/036 ,  B82Y15/00 ,  B82Y30/00 ,  G01N2291/0256 ,  G01N2291/0257

    摘要： A system having reduced gas interference that includes a fluid chamber and a resonant sensor device in fluid communication with a fluid in the fluid chamber. The system includes a fluid control device adapted to change at least one of the fluid flow or pressure within the fluid chamber to achieve substantial wetting of surfaces in proximity to the resonant sensor device. Fluid surfaces of the system can include a material to increase the wettability (e.g., hydrophilicity) of the fluid surfaces.

    摘要翻译： 具有减小的气体干扰的系统，其包括与流体室中的流体流体连通的流体室和谐振传感器装置。 该系统包括流体控制装置，其适于改变流体室内的流体流动或压力中的至少一个，以实现靠近谐振传感器装置的表面的显着润湿。 系统的流体表面可以包括增加流体表面的润湿性（例如亲水性）的材料。

    METHOD AND APPARATUS FOR ANALYTE PROCESSING
    7.
    发明申请
    METHOD AND APPARATUS FOR ANALYTE PROCESSING 有权
    分析方法和装置

    公开(公告)号：US20090269248A1

    公开(公告)日：2009-10-29

    申请号：US12175037

    申请日：2008-07-17

    申请人： Peter W. Falb ,  David Brancazio ,  Eric France ,  Brett P. Masters ,  Michael F. Miller ,  Joshua R. Ormsby ,  Walker Sloan

    发明人： Peter W. Falb ,  David Brancazio ,  Eric France ,  Brett P. Masters ,  Michael F. Miller ,  Joshua R. Ormsby ,  Walker Sloan

    IPC分类号： B01L3/00 ,  B23P17/04

    CPC分类号： G01N35/00029 ,  B01L3/5025 ,  B01L3/502715 ,  B01L3/502738 ,  B01L2200/025 ,  B01L2200/16 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2400/0487 ,  B01L2400/0655 ,  G01N2035/00148 ,  Y10T29/49

    摘要： A system for processing analytes in samples includes an instrument and a cartridge. The cartridge includes fluid inputs, input and output valve assemblies, processing devices, fluid reservoirs, and channels for carrying samples from the fluid inputs to the fluid reservoirs. The valve assemblies include valves adapted to form a sealed fluid chamber in response to force applied by a movable head assembly of the instrument. Each fluid reservoir is adapted to mate and align with an air displacement pump interface member. A valve assembly includes a recess wall surrounding a recess and a valve assembly wall surrounding both the recess and the recess wall. The recess wall and the valve assembly walls are adapted to mate with and seal against a flexible sheet covering the recess, the recess wall, and the valve assembly wall. The cartridge and instrument include complementary features for finely and coarsely aligning instrument assemblies with portions of the cartridge.

    摘要翻译： 用于处理样品中分析物的系统包括仪器和墨盒。 墨盒包括流体输入，输入和输出阀组件，处理装置，流体储存器和用于将样品从流体输入传送到流体储存器的通道。 阀组件包括适于响应由仪器的可移动头组件施加的力而形成密封流体室的阀。 每个流体储存器适于与排气泵接口构件配合和对准。 阀组件包括围绕凹部的凹陷壁和围绕凹部和凹陷壁的阀组件壁。 凹陷壁和阀组件壁适于与覆盖凹部，凹陷壁和阀组件壁的柔性薄片配合并密封。 墨盒和仪器包括用于精细和粗略地对准具有部分墨盒的仪器组件的互补特征。

    Electrically responsive device
    9.
    发明授权
    Electrically responsive device 有权
    电响应装置

    公开(公告)号：US08536037B2

    公开(公告)日：2013-09-17

    申请号：US11398308

    申请日：2006-04-05

    申请人： Brett P. Masters ,  Michael F. Miller

    发明人： Brett P. Masters ,  Michael F. Miller

    IPC分类号： G01T1/00

    CPC分类号： G01N29/036 ,  G01N9/002 ,  G01N2291/0256

    摘要： Electrically responsive devices and methods for fabricating electrically responsive devices involves applying an electrically responsive material (e.g., an electroactive material) over at least a portion of a surface of a substrate material and applying an electrode material over at least a portion of a surface of the electrically responsive material. At least one region of the electrode material is selectively removed exposing the electrically responsive material. At least some of the electrically responsive material is selectively removed in a region corresponding to the at least one region of the electrode material.

    摘要翻译： 用于制造电响应装置的电响应装置和方法包括在基底材料的表面的至少一部分上施加电响应材料（例如，电活性材料），并将电极材料施加到至少一部分表面上 电响应材料。 选择性地去除电极材料的至少一个区域，暴露出电响应材料。 在对应于电极材料的至少一个区域的区域中选择性地去除至少一些电响应材料。