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公开(公告)号：US20100185106A1
公开(公告)日：2010-07-22
申请号：US12376630
申请日：2007-08-06
IPC分类号： A61B5/02
CPC分类号： G01S17/58 , A61B5/027 , G01S7/4811 , G02B6/2726 , G02B6/2773
摘要： The invention relates to a light-emitting apparatus (100) comprising an optical waveguide, particularly an optical fiber (1), for guiding a primary light beam (Bprim) into a light-splitting unit (101) which splits it into two or more partial light beams (B1, B3, B4) which are emitted in different directions and have different optical qualities, e.g. different spectral compositions or polarizations. The apparatus may optionally comprise a detector (4) for determining a Doppler shift (Δλi) in reflected light reentering the light-splitting unit (101). This renders it possible to measure simultaneously two or more spatially independent vector components of the flow velocity of a fluid, particularly of blood, surrounding the light-splitting unit (101).
摘要翻译： 本发明涉及一种发光装置（100），其包括用于将初级光束（Bprim）引导到光分离单元（101）中的光波导，特别是光纤（1），其将其分成两个或更多个 在不同方向发射并具有不同光学质量的部分光束（B1，B3，B4），例如， 不同的光谱组成或极化。 该装置可以可选地包括用于确定重新进入光分离单元（101）的反射光中的多普勒频移（＆Dgr;λi）的检测器（4）。 这使得可以同时测量围绕光分离单元（101）的流体（特别是血液）的流速的两个或更多个空间上独立的矢量分量。
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2.发明申请CATHETER WITH ULTRASOUND TRANSDUCER AND VARIABLE FOCUS LENS USED IN ANEURYSM ASSESSMENT 审中-公开超声波传感器和可变焦度镜头用于防护评估的导管公开(公告)号：US20100076317A1
公开(公告)日：2010-03-25
申请号：US12516617
申请日：2007-11-16
IPC分类号： A61B8/14
CPC分类号： A61B8/12 , A61B5/02014 , A61B8/06 , A61B8/445 , A61B8/4483 , A61B8/483 , A61B17/12113 , A61B17/1214 , A61B2017/1205 , G10K11/30
摘要： A catheter having ultrasound capability and a distal end extending along a longitudinal axis, the end being situated adjacent to a tissue of interest inside of a patient; at least one ultrasound transducer located in the end to direct ultrasound waves along the axis in a generally forward direction relative to the end; a variable-focus lens system located in the end, downstream of the transducer in the generally forward direction, the lens system being capable of variably focusing the ultrasound waves emitted by the transducer at various positions downstream of the lens and catheter end; optionally, a mirror located in the end, downstream of the transducer and the lens system in the generally forward direction, whereby the emitted ultrasound waves from the lens system are either reflected from the mirror and focused at a position substantially perpendicular to the longitudinal axis; or the emitted ultrasound waves from the lens system substantially bypass the mirror in unreflected form and are focused at a position downstream of the transducer, the lens system and the mirror in the generally forward direction along the longitudinal axis; and imaging means for translating the focused ultrasound waves from the lens system reflected and/or unreflected by the mirror into three-dimensional images and communicating the images in viewable form to a human operator that is external to the patient. A method of measuring, imaging and viewing blood flow velocity and patterns in a blood vessel and aneurysm, as well as monitoring vaso-occlusive coil placement in an aneurysm during a surgical intervention using the catheter, is also disclosed.
摘要翻译： 具有超声波能力的导管和沿着纵向轴线延伸的远端，所述端部位于与患者体内的感兴趣组织相邻的位置; 位于所述端部的至少一个超声波换能器沿着所述轴线在相对于所述端部的大致向前方向上引导超声波; 可变焦距透镜系统位于传感器的大致向前方的下游，透镜系统能够在透镜和导管端的下游的各个位置处可变地聚焦由换能器发射的超声波; 可选地，位于换能器下游的镜子和大致正向的透镜系统，由此来自透镜系统的发射的超声波或者从反射镜反射并且在基本上垂直于纵向轴线的位置聚焦; 或者来自透镜系统的发射的超声波基本上以未反射的形式旁路反射镜，并且沿着纵轴在大致向前的方向上聚焦在换能器，透镜系统和反射镜的下游位置处; 以及成像装置，用于将由镜子反射和/或未反射的透镜系统的聚焦超声波转换为三维图像，并将可视形式的图像传送给患者外部的人类操作者。 还公开了一种在使用导管的外科手术中测量，成像和观察血管和动脉瘤中的血流速度和图案的方法以及监测动脉瘤中的血管闭塞线圈放置。
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公开(公告)号：US20110002517A1
公开(公告)日：2011-01-06
申请号：US12920330
申请日：2009-03-02
申请人： Sabine Mollus , Joerg Bredno , Juergen Weese , Drazenko Babic
发明人： Sabine Mollus , Joerg Bredno , Juergen Weese , Drazenko Babic
IPC分类号： G06T7/00
摘要： A method of analyzing a tube system in particular by image processing of images of the tube system is provided by the present invention. In order to achieve a simulation of a medium flow through a calculated tube model, the present invention gathers a tube model from a specific tube data set. By defining the necessary parameters of a virtual injection of the medium by the user, the medium flows through the model. Using this displayed simulation for generating at least two images leads to an artificial image sequence that might support a person, which wants to examine a real structure, that corresponds to the calculated model. This might be seen in.
摘要翻译： 通过本发明提供了一种分析管系统的方法，特别是通过管系统的图像的图像处理来分析管系统。 为了通过计算的管模型实现介质流的模拟，本发明从特定的管数据集中收集管模型。 通过定义用户对介质的虚拟注入的必要参数，介质流经模型。 使用该显示的模拟来生成至少两个图像，导致可能支持想要检查与计算出的模型相对应的真实结构的人的人造图像序列。 这可能在。
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4.发明授权System and method for generating images of a patient's interior and exterior 有权用于产生患者内部和外部的图像的系统和方法公开(公告)号：US08553839B2
公开(公告)日：2013-10-08
申请号：US13134537
申请日：2009-12-04
IPC分类号： G01N23/04
CPC分类号： A61B6/5235 , A61B6/4423 , A61B6/4441 , A61B6/5247 , A61B90/361 , A61B2090/364 , A61B2090/366 , A61B2090/371 , A61B2090/376
摘要： A system for generating an image including information of both an interior and an exterior of a patient. The system includes an X ray device for providing an X ray image of a patient's interior, and a camera responsive to a wavelength for providing a camera image of a patient's exterior. The camera may be supported by the X ray device for establishing a determined spatial relationship between the camera and the X ray device. The system further includes a spatial reference for spatially correlating the X ray image and the camera image, where the spatial reference is detectable in the X ray image and in the camera image. A data processor configured for rendering the camera image and the X ray image into a composite image on the basis of the spatial reference.
摘要翻译： 一种用于生成包括患者的内部和外部的信息的图像的系统。 该系统包括用于提供患者内部的X射线图像的X射线装置和响应于用于提供患者外部的照相机图像的波长的照相机。 照相机可以由X射线装置支持，以建立照相机和X射线装置之间确定的空间关系。 该系统还包括用于空间上相关X射线图像和相机图像的空间参考，其中空间参考在X射线图像和相机图像中是可检测的。 一种数据处理器，被配置为基于空间参考将相机图像和X射线图像渲染成合成图像。
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5.发明申请System and method for generating images of a patient's interior and exterior 有权用于产生患者内部和外部的图像的系统和方法公开(公告)号：US20120008741A1
公开(公告)日：2012-01-12
申请号：US13134537
申请日：2011-06-09
CPC分类号： A61B6/5235 , A61B6/4423 , A61B6/4441 , A61B6/5247 , A61B90/361 , A61B2090/364 , A61B2090/366 , A61B2090/371 , A61B2090/376
摘要： A system for generating an image including information of both an interior and an exterior of a patient. The system includes an X ray device for providing an X ray image of a patient's interior, and a camera responsive to a wavelength for providing a camera image of a patient's exterior. The camera may be supported by the X ray device for establishing a determined spatial relationship between the camera and the X ray device. The system further includes a spatial reference for spatially correlating the X ray image and the camera image, where the spatial reference is detectable in the X ray image and in the camera image. A data processor configured for rendering the camera image and the X ray image into a composite image on the basis of the spatial reference.
摘要翻译： 一种用于生成包括患者的内部和外部的信息的图像的系统。 该系统包括用于提供患者内部的X射线图像的X射线装置和响应于用于提供患者外部的照相机图像的波长的照相机。 照相机可以由X射线装置支持，以建立照相机和X射线装置之间确定的空间关系。 该系统还包括用于空间上相关X射线图像和相机图像的空间参考，其中空间参考在X射线图像和相机图像中是可检测的。 一种数据处理器，被配置为基于空间参考将相机图像和X射线图像渲染成合成图像。
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公开(公告)号：US09724071B2
公开(公告)日：2017-08-08
申请号：US13825865
申请日：2011-09-09
申请人： Szabolcs Deladi , Maya Barley , Niels Bakker , Drazenko Babic
发明人： Szabolcs Deladi , Maya Barley , Niels Bakker , Drazenko Babic
IPC分类号： A61B8/14 , A61B8/00 , A61B5/06 , A61B5/00 , A61B8/08 , A61B8/12 , A61B34/20 , A61B6/12 , A61B90/00
CPC分类号： A61B8/4254 , A61B5/066 , A61B5/489 , A61B6/12 , A61B8/085 , A61B8/0891 , A61B8/12 , A61B8/445 , A61B34/20 , A61B2034/2051 , A61B2090/378
摘要： A system, device and method include an interventional device having at least one ultrasonic transducer configured to generate a signal to indicate presence of a branch or bifurcation of a lumen inside a subject. A localization system is configured to track the interventional device in the subject. A program module is implemented by a processor to compare a position of the interventional device against a reference image and to indicate the presence of the branch or bifurcation relative to the interventional device position in accordance with the signal.
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公开(公告)号：US09179985B2
公开(公告)日：2015-11-10
申请号：US12867267
申请日：2009-02-27
CPC分类号： A61B5/6848 , A61B5/0066 , A61B5/0075 , A61B5/0084 , A61B10/0275 , A61B10/04 , A61B17/3403 , A61B17/3421 , A61B34/20 , A61B2017/00061 , A61B2017/00066 , A61B2034/2051 , A61B2090/306 , A61B2090/378 , A61B2576/00
摘要： A system for providing integrated guidance for positioning a needle in a body has two levels of guidance: a coarse guidance and a fine guidance. The system includes a non-invasive tracking system for tracing the biopsy device in the body, for providing the coarse guidance. Furthermore, the system includes an optical detector mounted on the needle for obtaining optical information discriminating tissue in the body, for providing the fine guidance.
摘要翻译： 用于提供用于将针定位在身体中的集成指导的系统具有两个指导级别：粗略的引导和精细的引导。 该系统包括用于跟踪身体中活检装置的非侵入性跟踪系统，用于提供粗略的引导。 此外，该系统包括安装在针上的光学检测器，用于获得识别身体中的组织的光学信息，以提供精细引导。
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公开(公告)号：US20140003698A1
公开(公告)日：2014-01-02
申请号：US14005620
申请日：2012-03-01
IPC分类号： A61B6/00
CPC分类号： A61B6/501 , A61B6/461 , A61B6/467 , A61B6/5217 , A61B6/5235 , A61B6/5247 , G06T7/33 , G06T2207/10072 , G06T2207/30016 , G06T2207/30101
摘要： The present invention relates to the determination of brain deformation. The invention relates in particular to a device for tracking brain deformation, an imaging system for tracking brain deformation, a method for tracking brain deformation, a method of operating a device for tracking brain deformation, as well as to a computer program element and a computer readable medium. For providing enhanced information about the brain deformation, a first 3D representation (112) of a cerebrovascular vessel structure of a region of interest of an object is provided (110) and (114) a second 3D representation (116) of the cerebrovascular vessel structure. Then, at least a part of the first 3D representation is elastically three dimensionally registered (118) with at least a part of the second 3D representation. A deformation field (122) of the cerebrovascular vessel structure is determined (120) based on the elastic registration. The determined vessel deformation is applied (124) to a brain structure representation to determine a deformation (126) of the cerebral structure. For example, planning data (130) for an intervention of the cerebral structure is provided (132) and the determined deformation of the cerebral structure is applied (134) to the planning data to generate deformation adjusted planning data (136).
摘要翻译： 本发明涉及脑变形的确定。 本发明特别涉及用于跟踪脑变形的装置，用于跟踪脑变形的成像系统，跟踪脑变形的方法，操作用于跟踪脑变形的装置的方法，以及计算机程序元件和计算机 可读介质。 为了提供关于脑部变形的增强信息，提供了一种对象的感兴趣区域的脑血管血管结构的第一3D表示（112）（110）和（114）脑血管血管结构的第二3D表示（116） 。 然后，第一3D表示的至少一部分用第二3D表示的至少一部分弹性三维地记录（118）。 基于弹性配准确定脑血管血管结构的变形场（122）（120）。 将确定的血管变形（124）应用于脑结构表示以确定脑结构的变形（126）。 例如，提供用于大脑结构的干预的规划数据（130）（132），并且将所确定的脑结构的变形（134）应用于规划数据以产生变形调整后的规划数据（136）。
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9.发明申请公开(公告)号：US20130303888A1
公开(公告)日：2013-11-14
申请号：US13825865
申请日：2011-09-09
申请人： Szabolcs Deladi , Maya Barley , Niels Bakker , Drazenko Babic
发明人： Szabolcs Deladi , Maya Barley , Niels Bakker , Drazenko Babic
IPC分类号： A61B8/00
CPC分类号： A61B8/4254 , A61B5/066 , A61B5/489 , A61B6/12 , A61B8/085 , A61B8/0891 , A61B8/12 , A61B8/445 , A61B34/20 , A61B2034/2051 , A61B2090/378
摘要： A system, device and method include an interventional device (106) including one or more ultrasonic transducers (108) configured to generate a signal to indicate presence of a branch or bifurcation of a lumen inside a subject. A localization system (102) is configured to track the interventional device in the subject. A program module (122) is implemented by a processor to compare a position of the interventional device against a reference image (130) and to indicate the presence of the branch or bifurcation relative to the position in accordance with the signal.
摘要翻译： 系统，装置和方法包括介入装置（106），其包括一个或多个超声波换能器（108），其构造成产生信号以指示对象内的管腔的分支或分叉的存在。 定位系统（102）被配置为跟踪被摄体中的介入装置。 程序模块（122）由处理器实现，以将介入装置的位置与参考图像（130）进行比较，并根据该信号指示相对于该位置的分支或分支的存在。
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10.发明申请公开(公告)号：US20120170824A1
公开(公告)日：2012-07-05
申请号：US13320358
申请日：2010-05-10
申请人： Bernardus Hendrikus Wilhelmus Hendriks , Michael Cornelis Van Beek , Peter-Andre Redert , Frederik Jan De Bruijn , Drazenko Babic , Robert Johannes Frederik Homan , Ralph Braspenning , Wei Pien Lee , Karl Catharina Van Bree , Caifeng Shan
发明人： Bernardus Hendrikus Wilhelmus Hendriks , Michael Cornelis Van Beek , Peter-Andre Redert , Frederik Jan De Bruijn , Drazenko Babic , Robert Johannes Frederik Homan , Ralph Braspenning , Wei Pien Lee , Karl Catharina Van Bree , Caifeng Shan
IPC分类号： G06K9/00
CPC分类号： A61B6/025 , A61B6/4423 , A61B6/4441 , A61B6/5247 , A61B90/361 , A61B90/39 , A61B2090/376
摘要： The invention provides a system (102) for accurately detecting a patient's (114) movement during imaging procedures. The system comprises a camera (126) for providing a stream of camera images of a part of a patient's exterior (206). The system (102) furthermore comprises a fiducial element (116), which fiducial element (116) is mountable on said part of the patient's exterior (206), and which fiducial element (116) is detectable in the stream of camera images, and an image processor (128) for detecting a displacement of the fiducial element based on consecutive camera images comprised in at least the stream of camera images and for generating an output signal (129) indicative for said displacement. Herein, the fiducial element (116) has an in-plane stiffness which is substantially larger than an in-plane stiffness of said part of the patient's exterior. In addition, the fiducial element (116) and said part of the patient's exterior are provided with substantially equal outer in-plane dimensions.
摘要翻译： 本发明提供一种用于在成像过程期间准确地检测患者（114）运动的系统（102）。 该系统包括用于提供患者外部（206）的一部分的相机图像流的照相机（126）。 所述系统（102）还包括基准元件（116），所述基准元件（116）可安装在所述患者外部部分（206）的所述部分上，并且所述基准元件（116）在相机图像流中是可检测的，以及 图像处理器（128），用于基于包括在至少相机图像流中的连续相机图像来检测基准元素的位移，并且用于生成指示所述位移的输出信号（129）。 这里，基准元件（116）具有的面内刚度基本上大于患者外部部分的平面内刚度。 此外，基准元件（116）和患者外部的所述部分设置有基本上相等的外部平面外尺寸。
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