Dental cement composition containing composite particles with grafted polyacidic polymer chains
    1.
    发明申请
    Dental cement composition containing composite particles with grafted polyacidic polymer chains 审中-公开
    含有接枝多酸聚合物链的复合颗粒的牙科水泥组合物

    公开(公告)号:US20070004820A1

    公开(公告)日:2007-01-04

    申请号:US11217542

    申请日:2005-09-01

    IPC分类号: A61K6/10

    摘要: A dental cement composition comprising (i) a particulate reactive inorganic filler capable of leaching metal ions in the presence of an acid, and (ii) composite particles with grafted polyacidic polymer chains, which are obtainable by a process comprising the following steps: (a) polymerizing one or more free radically polymerizable monomers containing optionally protected acidic groups in the presence of (a1) an initiatior system comprising initiator particles displaying a moiety comprising a radically transferable atom or group as a polymerization initiation site; and (a2) a catalyst facilitating controlled/living polymerisation, and (a3) optionally further polymerizable monomers, for forming a composite particle with grafted optionally protected polyacidic polymer chains; and (b) optionally deprotecting protected acidic groups, for forming composite particles with grafted polyacidic polymer chains.

    摘要翻译: 一种牙科水泥组合物,其包含(i)能够在酸存在下浸出金属离子的颗粒状反应性无机填料,和(ii)具有接枝多酸聚合物链的复合颗粒,其可通过包括以下步骤的方法获得:(a )在(a1)包含引发颗粒的引发剂体系的存在下聚合含有任选保护的酸性基团的一种或多种可自由基聚合的单体,所述引发剂颗粒显示包含可自由基转移的原子或基团的部分作为聚合引发位点; 和(a2)促进受控/活性聚合的催化剂,和(a3)任选的其它可聚合单体,用于形成具有接枝的任选保护的多酸聚合物链的复合颗粒; 和(b)任选地去保护受保护的酸性基团,以形成具有接枝的多酸聚合物链的复合颗粒。

    Dental cement composition containing composite particles with grafted polyacidic polymer chains
    2.
    发明申请
    Dental cement composition containing composite particles with grafted polyacidic polymer chains 审中-公开
    含有接枝多酸聚合物链的复合颗粒的牙科水泥组合物

    公开(公告)号:US20090030110A1

    公开(公告)日:2009-01-29

    申请号:US12284275

    申请日:2008-09-19

    IPC分类号: A61K6/08

    摘要: A dental cement composition comprising (i) a particulate reactive inorganic filler capable of leaching metal ions in the presence of an acid, and (ii) composite particles with grafted polyacidic polymer chains, which are obtainable by a process comprising the following steps: (a) polymerizing one or more free radically polymerizable monomers containing optionally protected acidic groups in the presence of (a1) an initiatior system comprising initiator particles displaying a moiety comprising a radically transferable atom or group as a polymerization initiation site; and (a2) a catalyst facilitating controlledliving polymerisation, and (a3) optionally further polymerizable monomers, for forming a composite particle with grafted optionally protected polyacidic polymer chains; and (b) optionally deprotecting protected acidic groups, for forming composite particles with grafted polyacidic polymer chains.

    摘要翻译: 一种牙科水泥组合物,其包含(i)能够在酸存在下浸出金属离子的颗粒状反应性无机填料,和(ii)具有接枝多酸聚合物链的复合颗粒,其可通过包括以下步骤的方法获得:(a )在(a1)包含引发颗粒的引发剂体系的存在下聚合含有任选保护的酸性基团的一种或多种可自由基聚合的单体,所述引发剂颗粒显示包含可自由基转移的原子或基团的部分作为聚合引发位点; 和(a2)促进受控聚合的催化剂,和(a3)任选的其它可聚合单体,用于形成具有接枝的任选保护的多酸聚合物链的复合颗粒; 和(b)任选地去保护受保护的酸性基团,以形成具有接枝的多酸聚合物链的复合颗粒。

    Method of detecting substance
    3.
    发明申请
    Method of detecting substance 审中-公开
    物质检测方法

    公开(公告)号:US20050112564A1

    公开(公告)日:2005-05-26

    申请号:US10182613

    申请日:2001-02-07

    摘要: The present invention relates to a method of detecting a substance to be detected in a sample characterized by mixing a sample containing the substance to be detected, in a solution, with carriers which have a shape such that, when suspended in a solution and flowed through a hollow tube for detecting signals formed in a signal detecting means capable of detecting a signal A and a signal B, two or more of the carriers do not move in an overlapping manner to the cross section of the hollow tube, to which a substance capable of binding to the substance to be detected (hereinafter referred simply to as “binding element”) is bound through or not through a spacer, and which have an identifiable signal A; binding the substance to be detected to said binding element thereby causing a signal B to be formed on the carriers; flowing a suspension of said carriers through the hollow tube by a solution supply means connected to the hollow tube; detecting the signal A and the signal B by the signal detecting means; and relating the signal A with the signal B.

    摘要翻译: 本发明涉及一种在样品中检测待检测物质的方法,其特征在于将溶液中含有待检测物质的样品与载体混合,所述载体的形状使得当悬浮在溶液中并流过 用于检测形成在能够检测信号A和信号B的信号检测装置中的信号的中空管,两个或更多个载体不以与中空管的横截面重叠的方式移动,能够 (以下简称为“结合元件”)通过或不通过间隔物结合并具有可识别信号A; 将要检测的物质结合到所述结合元件,从而在载体上形成信号B; 通过连接到中空管的溶液供应装置使所述载体的悬浮液流过中空管; 通过信号检测装置检测信号A和信号B; 并将信号A与信号B相关联。

    Charged component detector, its using method and detection panel
    7.
    发明申请
    Charged component detector, its using method and detection panel 审中-公开
    带电元件检测器,其使用方法和检测面板

    公开(公告)号:US20050037348A1

    公开(公告)日:2005-02-17

    申请号:US10468227

    申请日:2002-02-14

    IPC分类号: G01N27/12 C12Q1/68 C12M1/34

    CPC分类号: G01N27/128

    摘要: The present invention provides a charged substance detector capable of detecting charged substances easily and quickly without complicating the construction of the detector, a method of using the charged substance detector and a detection panel. The charged substance detector comprises: a detection panel 1 having a plurality of reaction electrodes 2 arrayed in matrix, on which are immobilized reaction charged substances reacting specifically with target charged substances; and a conduction control device 4 having a matrix of wires 3 crossing each other at points corresponding to the matrix-arrayed reaction electrodes 2 of the detection panel 1, and being capable of selectively energizing the reaction electrodes 2 through the matrix of wires 3. Further, to detect a state of reaction in each of the reaction electrodes 2, the conduction control device 4 is provided with a conduction state detector 5. By selectively applying a voltage to a specific reaction electrode 2, the reaction charged substance immobilized on the reaction electrode 2 is allowed to react specifically with a target charged substance. Further, the present invention also covers the detection panel 1 constituting the charged substance detector.

    摘要翻译: 本发明提供一种能够容易且快速地检测带电物质而不使检测器的结构复杂化的带电物质检测器,使用带电物质检测器和检测面板的方法。 带电物质检测器包括:具有排列成矩阵状的多个反应电极2的检测面板1,其上固定反应带电物质与目标带电物质特异性反应; 以及导电控制装置4,其具有在与检测面板1的矩阵排列的反应电极2对应的点处彼此交叉的导线3的矩阵,并且能够通过线3的矩阵选择性地激励反应电极2。 为了检测每个反应电极2中的反应状态,导通控制装置4设置有导通状态检测器5.通过选择性地向特定的反应电极2施加电压,固定在反应电极上的反应带电物质 2被允许与目标带电物质特异性地反应。 此外,本发明还包括构成带电物质检测器的检测面板1。