公开(公告)号：US08423619B2

公开(公告)日：2013-04-16

申请号：US12727831

申请日：2010-03-19

申请人： John Christopher Hawkins ,  Francis N. Parr ,  Hao Yang

发明人： John Christopher Hawkins ,  Francis N. Parr ,  Hao Yang

IPC分类号： G06F15/16

CPC分类号： G06F9/542 ,  G06F2209/544

摘要： Message brokering in a consuming broker device of a publish-subscribe system having at least one processor includes: designating in the consuming broker device a first producing broker device as a sole provider of messages having a topic to which the consuming broker device has subscribed; and in response to a determination that a measured livelihood of the first producing broker device is less than a defined threshold, designating with the consuming broker device a second producing broker device as the sole provider of the messages having the topic to the consuming broker device. The second producing broker device has a measured livelihood that is greater than the measured livelihood of the first producing broker device.

摘要翻译： 在具有至少一个处理器的发布订阅系统的消费代理设备中的消息代理包括：在消费代理设备中指定第一生产代理设备作为具有消费代理设备已订阅的主题的消息的唯一提供者; 并且响应于确定第一生产代理设备的测量生计小于定义的阈值，与消费代理设备一起指定作为具有该主题的消息的唯一提供者的第二生产代理设备到消费代理设备。 第二生产经纪人设备的测量生计大于第一生产经纪人设备的测量生计。

公开(公告)号：US20100241717A1

公开(公告)日：2010-09-23

申请号：US12727831

申请日：2010-03-19

申请人： John Christopher Hawkins ,  Francis Nicholas Parr ,  Hao Yang

发明人： John Christopher Hawkins ,  Francis Nicholas Parr ,  Hao Yang

IPC分类号： G06F15/16

CPC分类号： G06F9/542 ,  G06F2209/544

摘要： Message brokering in a consuming broker device of a publish-subscribe system having at least one processor includes: designating in the consuming broker device a first producing broker device as a sole provider of messages having a topic to which the consuming broker device has subscribed; and in response to a determination that a measured livelihood of the first producing broker device is less than a defined threshold, designating with the consuming broker device a second producing broker device as the sole provider of the messages having the topic to the consuming broker device. The second producing broker device has a measured livelihood that is greater than the measured livelihood of the first producing broker device.

摘要翻译： 在具有至少一个处理器的发布订阅系统的消费代理设备中的消息代理包括：在消费代理设备中指定第一生产代理设备作为具有消费代理设备已订阅的主题的消息的唯一提供者; 并且响应于确定第一生产代理设备的测量生计小于定义的阈值，与消费代理设备一起指定作为具有该主题的消息的唯一提供者的第二生产代理设备到消费代理设备。 第二生产经纪人设备的测量生计大于第一生产经纪人设备的测量生计。

公开(公告)号：US10290444B2

公开(公告)日：2019-05-14

申请号：US12676549

申请日：2008-09-03

申请人： Changming Yang ,  Tzulin Yang ,  Chingwen Yang ,  Hao Yang

发明人： Changming Yang ,  Tzulin Yang ,  Chingwen Yang ,  Hao Yang

IPC分类号： H01C10/10 ,  H01C10/12 ,  H01H13/704

摘要： A cloth material that can form an electronic component includes a cloth material layer, which includes at least one crevice; and a conductive area included in the cloth material layer, wherein a shape of the crevice and a shape of the conductive area change with an outside force. A cloth material that can form an electronic component includes two cloth material layers stacked to form a crevice therebetween; and a conductive area located on the two cloth material layers spanning from one side of the crevice to the other side of the crevice, wherein a shape of the crevice and the conductive area changes with an outside force.

公开(公告)号：US09202937B2

公开(公告)日：2015-12-01

申请号：US13321960

申请日：2010-05-14

申请人： Alexander Dietrich Hölke ,  Deb Kumar Pal ,  Kia Yaw Kee ,  Hao Yang

发明人： Alexander Dietrich Hölke ,  Deb Kumar Pal ,  Kia Yaw Kee ,  Hao Yang

IPC分类号： H01L29/861 ,  H01L29/40

CPC分类号： H01L29/868 ,  H01L29/405 ,  H01L29/407 ,  H01L29/8611

摘要： A semiconductor device comprising: a p or p+ doped portion; an n or n+ doped portion separated from the p or p+ doped portion by a semiconductor drift portion; an insulating portion provided adjacent the drift portion and at least one of the doped portions in a region where the drift portion and said at least one doped portion meet; and at least one additional portion which is arranged for significantly reducing the variation of the electric field strength in said region when a voltage difference is applied between the doped portions.

摘要翻译： 一种半导体器件，包括：p或p +掺杂部分; 通过半导体漂移部分从p或p +掺杂部分分离的n或n +掺杂部分; 在所述漂移部分和所述至少一个掺杂部分相遇的区域中邻近所述漂移部分设置的绝缘部分和所述掺杂部分中的至少一个; 以及至少一个附加部分，其被设置为当在掺杂部分之间施加电压差时，显着地减小所述区域中的电场强度的变化。

公开(公告)号：US09108954B2

公开(公告)日：2015-08-18

申请号：US13576637

申请日：2011-01-30

申请人： Rong Yan ,  Hao Yang ,  Wen Hou ,  Yongxiang Xu

发明人： Rong Yan ,  Hao Yang ,  Wen Hou ,  Yongxiang Xu

IPC分类号： C07D417/12 ,  C07D417/14

CPC分类号： C07D417/12

摘要： Synthesis process of dasatinib is disclosed, which includes the step of reacting the compound of formula I with that of formula II to obtain the compound of formula III. Also disclosed is the compound of formula III which is used as an intermediate for synthesizing dasatinib. The substituents of R1, R2, R3 or R4 in formulae I, II or III are defined as in the description.

摘要翻译： 公开了达沙替尼的合成方法，其包括使式I化合物与式II化合物反应以获得式III化合物的步骤。 还公开了用作合成达沙替尼的中间体的式III化合物。 式I，II或III中的R 1，R 2，R 3或R 4的取代基如描述中所定义。

公开(公告)号：US09101620B2

公开(公告)日：2015-08-11

申请号：US13501437

申请日：2010-11-02

申请人： Rong Yan ,  Hao Yang ,  Yongxiang Xu

发明人： Rong Yan ,  Hao Yang ,  Yongxiang Xu

IPC分类号： C07D401/04 ,  A61K31/445 ,  A61K31/454

CPC分类号： A61K31/454 ,  C07D401/04

摘要： The present invention provides polymorph of 3-(4-amino-1-oxo-1,3-dihydro-2H-isoindole-2-yl)-piperidine-2,6-dione, and also the preparing methods and pharmaceutical compositions thereof.

摘要翻译： 本发明提供3-（4-氨基-1-氧代-1,3-二氢-2H-异吲哚-2-基） - 哌啶-2,6-二酮的多晶型物，以及其制备方法和药物组合物。

公开(公告)号：US20150215409A1

公开(公告)日：2015-07-30

申请号：US14424667

申请日：2012-09-04

申请人： Likhang Chow ,  Hao Yang ,  Zhen Liu

发明人： Likhang Chow ,  Hao Yang ,  Zhen Liu

IPC分类号： H04L29/08 ,  H04W4/02

CPC分类号： H04L67/18 ,  G06Q30/0259 ,  G06Q30/0261 ,  H04W4/021

摘要： A method, apparatus, computer program product and system are provided for providing mobile services via a scalable location-based publication/subscription comprising a subscription system. In this regard, a method is provided that includes receiving at least one subscription comprising a subscription area and at least one publication comprising a publication location. The method further includes determining a geohash representation of the subscription area and determining whether the at least one publication matches the at least one subscription based at least on the publication location and the geohash representation of the representation of the subscription area. The method further includes causing content associated with the at least one publication to be transmitted in an instance in which the at least one publication matches the at least one subscription.

摘要翻译： 提供了一种方法，装置，计算机程序产品和系统，用于经由包括订阅系统的可扩展的基于位置的发布/订阅来提供移动服务。 在这方面，提供了一种方法，其包括接收包括订阅区域的至少一个订阅和包含发布位置的至少一个发布。 所述方法还包括：确定所述订阅区域的地理位置表示，以及至少基于所述发布位置和所述订阅区域的表示的所述地理位置表示来确定所述至少一个发布是否匹配所述至少一个订阅。 所述方法还包括在所述至少一个出版物与所述至少一个订阅匹配的实例中引起与所述至少一个发布相关联的内容。

公开(公告)号：US08489722B2

公开(公告)日：2013-07-16

申请号：US12625437

申请日：2009-11-24

申请人： Kyriakos Karenos ,  Minkyong Kim ,  Hui Lei ,  Dimitrios Pendarakis ,  Hao Yang ,  Fan Ye

发明人： Kyriakos Karenos ,  Minkyong Kim ,  Hui Lei ,  Dimitrios Pendarakis ,  Hao Yang ,  Fan Ye

IPC分类号： G06F15/173 ,  H04L12/56

CPC分类号： H04L45/00 ,  H04L45/24 ,  H04L45/302

摘要： Techniques for transmitting data according to at least one quality of service requirement. A message path is calculated specifying a sequence of broker computers selected from a network of interconnected broker computers. The message path is statistically estimated to fulfill the at least one quality of service requirement. Quality of service metrics are received about the network of interconnected broker computers. If the message path is determined not to fulfill the quality of service requirement, a new message path is calculated specifying a new sequence of broker computers selected from the network of interconnected broker computers. The new message path is statistically estimated to fulfill the at least one quality of service requirement.

摘要翻译： 根据至少一种服务质量要求传输数据的技术。 计算消息路径，指定从互连代理计算机的网络中选择的代理计算机的序列。 统计估计消息路径以满足至少一个服务质量要求。 收到关于互联经纪电脑网络的服务质量指标。 如果消息路径被确定为不满足服务质量要求，则计算新的消息路径，指定从互连代理计算机的网络中选择的新的代理计算机序列。 统计估计新消息路径以满足至少一个服务质量要求。

公开(公告)号：US20130164856A1

公开(公告)日：2013-06-27

申请号：US13695869

申请日：2011-04-15

申请人： Mais J. Jebrail ,  Hao Yang ,  Aaron R. Wheeler

发明人： Mais J. Jebrail ,  Hao Yang ,  Aaron R. Wheeler

IPC分类号： G01N1/28

CPC分类号： B01L3/502792 ,  B01L3/502753 ,  B01L3/502784 ,  B01L2200/0631 ,  B01L2400/0427 ,  G01N2001/288 ,  G01N2001/4061 ,  H01J49/00 ,  Y10T436/25

摘要： Methods are provided for the preparation of a sample using a digital microfluidic platform and the optional subsequent mass analysis of an extracted analyte. A sample is dried, optionally on a solid phase support, and contacted with digital microfluidic array. An analyte present within the dried sample is extracted into an extraction solvent by electrically addressing the digital microfluidic array to transport a droplet of extraction solvent to the dried sample spot. The extracted sample may be dried and subsequently processed on the digital microfluidic array for derivatization. The digital microfluidic device may further include an integrated microfluidic channel having an output aperture, and the method may further include contacting a droplet containing extracted analyte with the microfluidic channel and applying a suitable electric field for generating nano-electrospray, thereby enabling the device to be directly interfaced with a mass analysis device.

摘要翻译： 提供了使用数字微流体平台制备样品的方法以及提取的分析物的随后的质量分析。 将样品干燥，任选地在固相载体上，并与数字微流体阵列接触。 将干燥样品中存在的分析物通过电解寻址数字微流体阵列将萃取溶剂的液滴输送到干燥的样品点而提取到萃取溶剂中。 提取的样品可以干燥并随后在数字微流体阵列上进行处理以进行衍生。 数字微流体装置还可以包括具有输出孔的集成微流体通道，并且该方法还可以包括使含有提取的分析物的液滴与微流体通道接触并施加合适的电场以产生纳米电喷雾，由此使得该装置能够 直接与质量分析装置连接。

公开(公告)号：US08331097B2

公开(公告)日：2012-12-11

申请号：US12676564

申请日：2008-09-03

申请人： Chang-Ming Yang ,  Tzulin Yang ,  Chingwen Yang ,  Hao Yang

发明人： Chang-Ming Yang ,  Tzulin Yang ,  Chingwen Yang ,  Hao Yang

IPC分类号： H05K1/00

CPC分类号： A61B5/6804 ,  A61B5/04085 ,  A61B5/11 ,  A61B2562/0252

摘要： A cloth material with separate conductive areas includes at least one first layer comprising at least one first conductive area; and at least one extension part, which includes at least one accessory and at least one connecting part connected to the accessory, wherein the extension part comprises at least one second conductive area, which corresponds in location to the first conductive area on the first layer, wherein the first conductive area and the second conductive area are inductively coupled, a condition of inductive coupling is adapted to be changed by an outside force.

摘要翻译： 具有分开导电区域的布料包括至少一个包含至少一个第一导电区域的第一层; 以及至少一个延伸部分，其包括连接到附件的至少一个附件和至少一个连接部分，其中所述延伸部分包括至少一个第二导电区域，其在位置上对应于第一层上的第一导电区域， 其中所述第一导电区域和所述第二导电区域感应耦合，所述电感耦合条件适于由外力改变。