公开(公告)号：US20100217187A1

公开(公告)日：2010-08-26

申请号：US12711100

申请日：2010-02-23

申请人： John FULKERSON ,  Andrew Cragg ,  David A. Ferrera

发明人： John FULKERSON ,  Andrew Cragg ,  David A. Ferrera

IPC分类号： A61M25/10 ,  A61M29/02

CPC分类号： A61B17/3207 ,  A61B17/221 ,  A61B17/320725 ,  A61B2017/00845 ,  A61B2017/00867 ,  A61B2017/22038 ,  A61B2017/22082 ,  A61F2/013 ,  A61F2/82 ,  A61F2250/0059 ,  A61M29/02 ,  A61M2025/1095 ,  A61M2025/1097

摘要： A microcatheter having an active segment reperfuses occluded blood vessels above the junction of the subclavian artery and common carotid artery. The microcatheter is used to penetrate emboli. Once an embolus is penetrated, the active segment of the microcatheter is activated, causing it to expand radially and thereby open a channel in the embolus. Thus, a channel for restored blood flow is created. The blood's natural lytic action further degraded the embolus in some cases. Therapeutic agents may be administered through the microcatheter to aid in the reperfusion process.

摘要翻译： 具有活动段的微导管重新灌注锁骨下动脉和颈总动脉交界处的闭塞血管。 微导管用于穿刺栓塞。 一旦栓塞被穿透，微导管的活动段被激活，导致其径向扩张，从而在栓塞中打开通道。 因此，产生用于恢复血流的通道。 在某些情况下，血液的天然溶解作用进一步降低了栓子。 治疗剂可以通过微导管给药以帮助再灌注过程。

公开(公告)号：US20090105737A1

公开(公告)日：2009-04-23

申请号：US12123390

申请日：2008-05-19

申请人： John Fulkerson ,  David A. Ferrera ,  Andrew Cragg

发明人： John Fulkerson ,  David A. Ferrera ,  Andrew Cragg

IPC分类号： A61B17/22 ,  A61M29/00 ,  A61F2/01 ,  A61F2/84 ,  A61M25/098

CPC分类号： A61B17/3207 ,  A61B17/221 ,  A61B17/320725 ,  A61B2017/00845 ,  A61B2017/00867 ,  A61B2017/22038 ,  A61B2017/22082 ,  A61F2/013 ,  A61F2/82 ,  A61F2250/0059 ,  A61M29/02 ,  A61M2025/1095 ,  A61M2025/1097

摘要： An acute stroke recanalization system and processes include catheter-based improved reconstrainable or tethered neurological devices which are deliverable through highly constricted and tortuous vessels, crossing the zone associated with subject thrombi/emboli, where deployment impacts, addresses or bridges the embolus, compacting the same into luminal walls which enables perfusion and lysis of the embolus, while the improved neurological medical device itself remains contiguous with the delivery system acting as a filter, basket or stand alone stenting mechanism, depending on the status of the embolus and other therapeutic aspects of the treatment being offered for consideration.

摘要翻译： 急性中风再通系统和过程包括基于导管的改善的可重建或系留的神经系统装置，其可通过高度收缩和曲折的血管交付，穿过与受试者血栓/栓塞相关的区域，其中部署影响，解决或桥接栓塞，压制相同 进入能够灌注和溶解栓塞的腔壁，而改进的神经医学装置本身与作为过滤器，篮子或独立支架机构的输送系统保持连续，这取决于栓塞的状态和其他治疗方面 治疗被提供考虑。

公开(公告)号：US20110190797A1

公开(公告)日：2011-08-04

申请号：US13084880

申请日：2011-04-12

申请人： John Fulkerson ,  David A. Ferrera ,  Andrew Cragg

发明人： John Fulkerson ,  David A. Ferrera ,  Andrew Cragg

IPC分类号： A61B17/22

CPC分类号： A61B17/3207 ,  A61B17/221 ,  A61B17/320725 ,  A61B2017/00845 ,  A61B2017/00867 ,  A61B2017/22038 ,  A61B2017/22082 ,  A61F2/013 ,  A61F2/82 ,  A61F2250/0059 ,  A61M29/02 ,  A61M2025/1095 ,  A61M2025/1097

摘要： An acute stroke recanalization system and processes include catheter-based improved reconstrainable or tethered neurological devices which are deliverable through highly constricted and tortuous vessels, crossing the zone associated with subject thrombi/emboli, where deployment impacts, addresses or bridges the embolus, compacting the same into luminal walls which enables perfusion and lysis of the embolus, while the improved neurological medical device itself remains contiguous with the delivery system acting as a filter, basket or stand alone stenting mechanism, depending on the status of the embolus and other therapeutic aspects of the treatment being offered for consideration.

摘要翻译： 急性中风再通系统和过程包括基于导管的改善的可重建或系留的神经系统装置，其可通过高度收缩和曲折的血管交付，穿过与受试者血栓/栓塞相关的区域，其中部署影响，解决或桥接栓塞，压制相同 进入能够灌注和溶解栓塞的腔壁，而改进的神经医学装置本身与作为过滤器，篮子或独立支架机构的输送系统保持连续，这取决于栓塞的状态和其他治疗方面 治疗被提供考虑。

公开(公告)号：US20100174309A1

公开(公告)日：2010-07-08

申请号：US12651353

申请日：2009-12-31

申请人： JOHN FULKERSON ,  David A. Ferrera ,  Andrew Cragg

发明人： JOHN FULKERSON ,  David A. Ferrera ,  Andrew Cragg

IPC分类号： A61B17/22

CPC分类号： A61M29/02 ,  A61B17/221 ,  A61B17/3207 ,  A61B17/320725 ,  A61B2017/00845 ,  A61B2017/00867 ,  A61B2017/22038 ,  A61F2/013 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91558 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/0059 ,  A61M2025/1095 ,  A61M2025/1097

摘要： An acute stroke recanalization systems and processes include catheter-based improved reconstrainable or tethered neurological devices which are deliverable through highly constricted and tortuous vessels, crossing the zone associated with subject thrombi/emboli, where deployment impacts, addresses or bridges the embolus, compacting the same into lumenal walls which enables perfusion and lysis of the embolus, while the improved neurological medical device itself remains contiguous with the delivery system acting as a filter, basket or stand alone alternate medical device, depending on the status of the embolus and other therapeutic aspects of the treatment being offered for consideration.

摘要翻译： 急性中风再通系统和过程包括基于导管的改善的可重建或系留神经系统装置，其可通过高度收缩和曲折的血管输送，穿过与受试者血栓/栓塞相关的区域，其中部署影响，解决或桥接栓塞，压制相同 进入管壁，其能够使栓塞的灌注和溶解，而改进的神经医学装置本身与作为过滤器，篮子或独立的替代医疗装置的输送系统保持连续，这取决于栓塞的状态和其他治疗方面 提供治疗提供考虑。

公开(公告)号：US09198687B2

公开(公告)日：2015-12-01

申请号：US12123390

申请日：2008-05-19

申请人： John Fulkerson ,  David A. Ferrera ,  Andrew Cragg

发明人： John Fulkerson ,  David A. Ferrera ,  Andrew Cragg

IPC分类号： A61F2/06 ,  A61B17/3207 ,  A61B17/221 ,  A61F2/82 ,  A61M29/02 ,  A61B17/00 ,  A61B17/22 ,  A61F2/01 ,  A61M25/10

CPC分类号： A61B17/3207 ,  A61B17/221 ,  A61B17/320725 ,  A61B2017/00845 ,  A61B2017/00867 ,  A61B2017/22038 ,  A61B2017/22082 ,  A61F2/013 ,  A61F2/82 ,  A61F2250/0059 ,  A61M29/02 ,  A61M2025/1095 ,  A61M2025/1097

摘要： An acute stroke recanalization system and processes include catheter-based improved reconstrainable or tethered neurological devices which are deliverable through highly constricted and tortuous vessels, crossing the zone associated with subject thrombi/emboli, where deployment impacts, addresses or bridges the embolus, compacting the same into luminal walls which enables perfusion and lysis of the embolus, while the improved neurological medical device itself remains contiguous with the delivery system acting as a filter, basket or stand alone stenting mechanism, depending on the status of the embolus and other therapeutic aspects of the treatment being offered for consideration.

摘要翻译： 急性中风再通系统和过程包括基于导管的改善的可重建或系留的神经系统装置，其可通过高度收缩和曲折的血管交付，穿过与受试者血栓/栓塞相关的区域，其中部署影响，解决或桥接栓塞，压制相同 进入能够灌注和溶解栓塞的腔壁，而改进的神经医学装置本身与作为过滤器，篮子或独立支架机构的输送系统保持连续，这取决于栓塞的状态和其他治疗方面 治疗被提供考虑。

公开(公告)号：US20100318097A1

公开(公告)日：2010-12-16

申请号：US12835497

申请日：2010-07-13

申请人： David A. Ferrera ,  John Fulkerson ,  Andrew Cragg

发明人： David A. Ferrera ,  John Fulkerson ,  Andrew Cragg

IPC分类号： A61B17/221

CPC分类号： A61B17/3207 ,  A61B17/221 ,  A61B17/320725 ,  A61B2017/00845 ,  A61B2017/00867 ,  A61B2017/22038 ,  A61B2017/22082 ,  A61F2/013 ,  A61F2/82 ,  A61F2250/0059 ,  A61M29/02 ,  A61M2025/1095 ,  A61M2025/1097

摘要： An acute stroke recanalization system and processes include catheter-based improved reconstrainable or tethered neurological devices which are deliverable through highly constricted and tortuous vessels, crossing the zone associated with subject thrombi/emboli, where deployment impacts, addresses or bridges the embolus, compacting the same into luminal walls which enables perfusion and lysis of the embolus, while the improved neurological medical device itself remains contiguous with the delivery system acting as a filter, basket or stand alone stenting mechanism, depending on the status of the embolus and other therapeutic aspects of the treatment being offered for consideration.

摘要翻译： 急性中风再通系统和过程包括基于导管的改善的可重建或系留的神经系统装置，其可通过高度收缩和曲折的血管交付，穿过与受试者血栓/栓塞相关的区域，其中部署影响，解决或桥接栓塞，压制相同 进入能够灌注和溶解栓塞的腔壁，而改进的神经医学装置本身与作为过滤器，篮子或独立支架机构的输送系统保持连续，这取决于栓塞的状态和其他治疗方面 治疗被提供考虑。

公开(公告)号：US20080065080A1

公开(公告)日：2008-03-13

申请号：US11942470

申请日：2007-11-19

申请人： Robert Assell ,  Steven Ainsworth ,  Andrew Cragg ,  Eugene Dickhudt

发明人： Robert Assell ,  Steven Ainsworth ,  Andrew Cragg ,  Eugene Dickhudt

IPC分类号： A61B17/00 ,  A61B17/58

CPC分类号： A61B17/7074 ,  A61B17/0218 ,  A61B17/025 ,  A61B17/1604 ,  A61B17/1615 ,  A61B17/1671 ,  A61B17/1697 ,  A61B17/1757 ,  A61B17/8615 ,  A61B17/888 ,  A61B17/8888 ,  A61B17/8897 ,  A61B2017/00261 ,  A61B2017/0046 ,  A61B2017/00469 ,  A61B2017/0256 ,  A61B2017/22038 ,  A61B2017/22044 ,  A61B2017/3445 ,  A61B2017/922

摘要： Disclosed are surgical tools, tool sets and methods for percutaneously accessing and preparing treatment sites within the spine for subsequent treatment procedures. The treatment site may be an inter-vertebral motion segments in the lumbar and sacral regions of the spine. The tool set may comprise introducer tools and bone dilators for accessing and tapping into a targeted site, such as, for example, the anterior surface of the S1 vertebral body. The tool set may also comprise cutters and extractors for preparing the treatment site for subsequent treatment procedures. The tool set may additionally comprise a bone graft inserter, an exchange system, and/or a temporary distraction tool for further preparing the treatment site for subsequent treatment procedures.

摘要翻译： 公开了用于经皮进入和制备脊柱内的治疗部位的手术工具，工具组和方法用于随后的治疗过程。 治疗部位可以是脊椎腰椎和骶骨区域中的椎间运动节段。 工具组可以包括导引器工具和骨扩张器，用于进入和攻击目标部位，例如S1椎体的前表面。 刀具组还可以包括切割器和提取器，用于为随后的处理程序制备治疗部位。 工具组可以另外包括骨移植物插入器，交换系统和/或临时牵引工具，用于进一步制备后续治疗过程的治疗部位。

公开(公告)号：US20080045922A1

公开(公告)日：2008-02-21

申请号：US11923495

申请日：2007-10-24

申请人： Andrew Cragg ,  Blair Walker ,  John Perl ,  Michael Jones ,  George Greene ,  George Wallace ,  Richard Greff

发明人： Andrew Cragg ,  Blair Walker ,  John Perl ,  Michael Jones ,  George Greene ,  George Wallace ,  Richard Greff

IPC分类号： A61M25/12

CPC分类号： A61B17/12195 ,  A61B17/00491 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12136 ,  A61B17/12168 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/00495 ,  A61B2017/00876 ,  A61B2017/00893 ,  A61B2017/1205 ,  A61B2017/12059 ,  A61B2017/12063 ,  A61M25/00 ,  A61M25/0028 ,  A61M25/0097 ,  A61M2025/0036 ,  A61M2025/004

摘要： A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream.

摘要翻译： 提供液体栓塞递送系统用于捕获注射的液体栓塞组合物以防止液体栓塞凝固或以其他方式通过栓塞区域外部。 递送系统包括用于输送液体栓塞组合物的导管和定位在导管远端的容纳构件，其被成形为捕获通过导管内腔输送的液体栓塞组合物。 容纳构件形成为注射液体栓塞组合物的周围的刷子，巢，海绵，拭子，柔性袋或其它形状。 在包含液体栓塞的凝固期间，液体栓塞组合物被捕获或与容纳构件啮合，并防止栓塞组合物进入血流。

公开(公告)号：US20070100369A1

公开(公告)日：2007-05-03

申请号：US11315925

申请日：2005-12-22

申请人： Andrew Cragg ,  Bobby Purkait ,  Rodolfo Quijano ,  Hosheng Tu

发明人： Andrew Cragg ,  Bobby Purkait ,  Rodolfo Quijano ,  Hosheng Tu

IPC分类号： A61M29/00

CPC分类号： A61F5/0076 ,  A61F5/003 ,  A61F5/0033 ,  A61F5/0036 ,  A61F5/004

摘要： A gastric space filler device for treating obesity in a patient by reducing the stomach volume comprising at least one inflatable space filler and a pressure sensor secured to the space filler, wherein the pressure sensor yields a noticeable signal for causing removal of the space filler.

摘要翻译： 一种胃空间填充装置，用于通过减少包括至少一个可充气空间填充物和固定在空间填充物上的压力传感器的胃体积来治疗患者的肥胖，其中所述压力传感器产生用于引起空间填充物移除的明显信号。

公开(公告)号：US20060264957A1

公开(公告)日：2006-11-23

申请号：US11460892

申请日：2006-07-28

申请人： Andrew Cragg ,  Jonathan Kagan

发明人： Andrew Cragg ,  Jonathan Kagan

IPC分类号： A61B17/00

CPC分类号： A61B17/3203 ,  A61B17/1617 ,  A61B17/1671 ,  A61B17/1757 ,  A61B17/32002 ,  A61B17/320725 ,  A61B17/66 ,  A61B17/70 ,  A61B17/7055 ,  A61B2017/00261 ,  A61B2017/00734 ,  A61B2017/00867 ,  A61B2017/2905 ,  A61B2017/320733 ,  A61F2/441 ,  A61F2/442 ,  A61F2/4455 ,  A61F2/4465 ,  A61F2/4601 ,  A61F2/4611 ,  A61F2002/2821 ,  A61F2002/2835 ,  A61F2002/30092 ,  A61F2002/30291 ,  A61F2002/3055 ,  A61F2002/30563 ,  A61F2002/30566 ,  A61F2002/30677 ,  A61F2002/30774 ,  A61F2002/30841 ,  A61F2002/3085 ,  A61F2002/30879 ,  A61F2002/30884 ,  A61F2002/30892 ,  A61F2002/30925 ,  A61F2002/3097 ,  A61F2002/4475 ,  A61F2002/448 ,  A61F2002/4631 ,  A61F2210/0014 ,  A61F2230/0091 ,  A61F2310/00353 ,  A61N5/1027

摘要： Methods and apparatus for and performing a partial or complete discectomy of an intervertebral spinal disc accessed by one or more trans-sacral axial spinal instrumentation/fusion (TASIF) axial bore formed through vertebral bodies in general alignment with a visualized, trans-sacral anterior or posterior axial instrumentation/fusion line (AAIFL or PAIFL) line. A discectomy instrument is introduced through the axial bore, the axial disc opening, and into the nucleus to locate a discectomy instrument cutting head at the distal end of the discectomy instrument shaft within the nucleus. The cutting head is operated by operating means coupled to the instrument body proximal end for extending the cutting head laterally away from the disc opening within the nucleus of the intervertebral spinal disc and for operating the cutting head to form a disc cavity within the annulus extending laterally and away from the disc opening or a disc space wherein the disc cavity extends through at least a portion of the annulus. A discectomy sheath that is first introduced to extend from the skin incision through the axial bore and into the axial disc opening having a discectomy sheath lumen that the discectomy instrument is introduced through. The discectomy sheath is preferably employed for irrigation and aspiration of the disc cavity or just aspiration if irrigation fluids are introduced through a discectomy instrument shaft lumen. The cutting head of the discectomy tool is deflected from the sheath lumen laterally and radially toward the annulus using a deflecting catheter or pull wire.

摘要翻译： 通过一个或多个通过椎体形成的跨骶骨轴向脊柱器械/融合（TASIF）轴向孔的椎间盘的部分或完全椎间盘切除术的方法和装置，其通常与可视化的跨骶前部或 后轴向仪器/融合线（AAIFL或PAIFL）线。 通过轴向孔，轴向盘开口和细胞核引入椎间盘切除仪，将椎间盘切除仪器切割头定位在细胞核内椎间盘切除术器械轴的远端。 切割头由耦合到仪器主体近端的操作装置操作，用于将切割头横向远离椎间盘脊髓核内的盘开口延伸，并且用于操作切割头以在侧向延伸的环形区域内形成盘腔 并且远离盘开口或盘空间，其中盘腔延伸穿过环的至少一部分。 首先引入的椎间盘切除鞘，其从皮肤切口延伸穿过轴向孔并进入具有椎间盘切除术器械引入的椎间盘切除鞘腔的轴向盘开口。 椎间盘切除鞘优选用于灌注和抽吸椎间盘腔，或者如果灌注液通过椎间盘切除术器具轴腔引入，则仅适于抽吸。 椎间盘切除工具的切割头使用偏转导管或拉丝线从鞘管侧向和径向地偏转到环形空间。