专利检索 ap:("John N. Simons" OR "Tami J. Pilot-Matias" OR "George J. Dawson" OR "George G. Schlauder" OR "Suresh M. Desai" OR "Thomas P. Leary" OR "Anthony Scott Muerhoff" OR "Sheri L. Buijk" OR "James Carl Erker" OR "Isa K. Mushahwar") AND inv:"John N. Simons" 第 1 页

1.

发明授权
Non-A, non-B, non-C, non-D, non-E Hepatitis reagents and methods for their use 失效
标题翻译：非A，非B，非C，非D，非E型肝炎试剂及其使用方法

公开(公告)号：US5981172A

公开(公告)日：1999-11-09

申请号：US417629

申请日：1995-04-06

申请人： John N. Simons , Tami J. Pilot-Matias , George J. Dawson , George G. Schlauder , Suresh M. Desai , Thomas P. Leary , Anthony Scott Muerhoff , Sheri L. Buijk , James Carl Erker , Isa K. Mushahwar

发明人： John N. Simons , Tami J. Pilot-Matias , George J. Dawson , George G. Schlauder , Suresh M. Desai , Thomas P. Leary , Anthony Scott Muerhoff , Sheri L. Buijk , James Carl Erker , Isa K. Mushahwar

IPC分类号： G01N33/53 , A61K38/00 , A61K39/00 , A61K39/29 , A61K39/395 , A61P1/16 , C07H21/04 , C07K14/02 , C07K14/08 , C07K14/10 , C07K14/18 , C07K16/10 , C12N5/10 , C12N15/09 , C12N15/40 , C12P21/02 , C12P21/08 , C12Q1/68 , C12Q1/70 , C12R1/19 , C12R1/92 , G01N33/531 , G01N33/566 , G01N33/576 , G01N33/577 , C07H21/02

CPC分类号： C07K14/005 , C12Q1/707 , G01N33/576 , A61K38/00 , A61K39/00 , C07K2319/00 , C12N2770/24222 , C12N2770/36022

摘要： Hepatitus GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and theraeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.

摘要翻译： 用于各种诊断和应用应用的肝癌GB病毒（HGBV）核酸和氨基酸序列，使用HGBV核酸或氨基酸序列的试剂盒，HGBV免疫原性颗粒和特异性结合HGBV的抗体。还提供了从HGBV核酸或氨基酸序列产生抗体，多克隆或单克隆抗体的方法。

2.

发明授权
Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use 失效

公开(公告)号：US6051374A

公开(公告)日：2000-04-18

申请号：US488445

申请日：1995-06-07

申请人： John N. Simons , Tami J. Pilot-Matias , George J. Dawson , George G. Schlauder , Suresh M. Desai , Thomas P. Leary , Anthony Scott Muerhoff , James Carl Erker , Sheri L. Buijk , Isa K. Mushahwar

发明人： John N. Simons , Tami J. Pilot-Matias , George J. Dawson , George G. Schlauder , Suresh M. Desai , Thomas P. Leary , Anthony Scott Muerhoff , James Carl Erker , Sheri L. Buijk , Isa K. Mushahwar

IPC分类号： A61K39/00 , C07K14/18 , C07K16/10 , C12Q1/70 , G01N33/576 , C12P19/34 , C07H21/02 , C07H21/04

CPC分类号： C07K14/005 , C07K16/109 , C12Q1/707 , G01N33/576 , A61K39/00 , C07K2319/00 , C12N2770/24222 , Y10S435/81 , Y10S530/826 , Y10S977/906 , Y10S977/915

摘要： Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.

3.

发明授权
Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use 失效

公开(公告)号：US06558898B1

公开(公告)日：2003-05-06

申请号：US08488446

申请日：1995-06-07

申请人： John N. Simons , Tami J. Pilot-Matias , George J. Dawson , George G. Schlauder , Suresh M. Desai , Thomas P. Leary , Anthony Scott Muerhoff , James Carl Erker , Sheri L. Buijk , Isa K. Mushahwar

发明人： John N. Simons , Tami J. Pilot-Matias , George J. Dawson , George G. Schlauder , Suresh M. Desai , Thomas P. Leary , Anthony Scott Muerhoff , James Carl Erker , Sheri L. Buijk , Isa K. Mushahwar

IPC分类号： C12Q170

CPC分类号： C07K14/005 , A61K39/00 , C07K16/109 , C07K2319/00 , C12N2770/24222 , C12Q1/707 , G01N33/576 , Y10S435/81 , Y10S530/826 , Y10S977/906 , Y10S977/915

摘要： Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.

4.

发明授权
Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use 失效
标题翻译：非A，非B，非C，非D，非E型肝炎试剂及其使用方法

公开(公告)号：US06451578B1

公开(公告)日：2002-09-17

申请号：US08469260

申请日：1995-06-06

申请人： John N. Simons , Tami J. Pilot-Matias , George J. Dawson , George G. Schlauder , Suresh M. Desai , Thomas P. Leary , Anthony Scott Muerhoff , James Carl Erker , Sheri L. Buijk , Isa K. Mushahwar

发明人： John N. Simons , Tami J. Pilot-Matias , George J. Dawson , George G. Schlauder , Suresh M. Desai , Thomas P. Leary , Anthony Scott Muerhoff , James Carl Erker , Sheri L. Buijk , Isa K. Mushahwar

IPC分类号： C12N700

CPC分类号： C07K14/005 , A61K39/00 , C07K16/109 , C07K2319/00 , C12N2770/24222 , C12Q1/707 , G01N33/576 , Y10S436/82 , Y10S977/803

摘要： Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.

摘要翻译： 用于各种诊断和治疗应用的乙型肝炎病毒（HGBV）核酸和氨基酸序列，用于使用HGBV核酸或氨基酸序列的试剂盒，HGBV免疫原性颗粒和特异性结合HGBV的抗体。还提供了从HGBV核酸或氨基酸序列产生抗体，多克隆或单克隆抗体的方法。

5.

发明授权
Non-a, non-b, non-c, non-c, non-d, non-e hepatitis reagents and methods for their use 失效
标题翻译：非a，非b，非c，非c，非d，非e型肝炎试剂及其使用方法

公开(公告)号：US06720166B2

公开(公告)日：2004-04-13

申请号：US08424550

申请日：1995-06-05

申请人： John N. Simons , Tami J. Pilot-Matias , George J. Dawson , George G. Schlauder , Suresh M. Desai , Thomas P. Leary , Anthony Scott Muerhoff , James Carl Erker , Sheri L. Buijk , Isa K. Mushahwar

发明人： John N. Simons , Tami J. Pilot-Matias , George J. Dawson , George G. Schlauder , Suresh M. Desai , Thomas P. Leary , Anthony Scott Muerhoff , James Carl Erker , Sheri L. Buijk , Isa K. Mushahwar

IPC分类号： C12P2102

CPC分类号： C07K14/005 , A61K39/00 , C07K16/109 , C07K2319/00 , C12N2770/24222 , C12Q1/707 , G01N33/576

摘要： Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.

摘要翻译： 用于各种诊断和治疗应用的乙型肝炎病毒（HGBV）核酸和氨基酸序列，用于使用HGBV核酸或氨基酸序列的试剂盒，HGBV免疫原性颗粒和特异性结合HGBV的抗体。还提供了从HGBV核酸或氨基酸序列产生抗体，多克隆或单克隆抗体的方法。

6.

发明授权
Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use 失效

公开(公告)号：US06586568B1

公开(公告)日：2003-07-01

申请号：US08467344

申请日：1995-06-06

申请人： John N. Simons , Tami J. Pilot-Matias , George J. Dawson , George G. Schlauder , Suresh M. Desai , Thomas P. Leary , Anthony Scott Muerhoff , James Carl Erker , Sheri L. Buijk , Isa K. Mushahwar

发明人： John N. Simons , Tami J. Pilot-Matias , George J. Dawson , George G. Schlauder , Suresh M. Desai , Thomas P. Leary , Anthony Scott Muerhoff , James Carl Erker , Sheri L. Buijk , Isa K. Mushahwar

IPC分类号： C07K700

CPC分类号： C07K14/005 , A61K39/00 , C07K16/109 , C07K2319/00 , C12N2770/24222 , C12Q1/707 , G01N33/576 , Y10S435/81 , Y10S530/826 , Y10S977/906 , Y10S977/915

摘要： Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.

7.

发明授权
Hepatitis GB virus recombinant proteins and uses thereof 失效
标题翻译：乙型肝炎病毒重组蛋白及其用途

公开(公告)号：US6156495A

公开(公告)日：2000-12-05

申请号：US629463

申请日：1996-04-19

申请人： Tami J. Pilot-Matias , Thomas P. Leary , John N. Simons , Robert J. Carrick , Teresa K. Surowy , Suresh M. Desai , George J. Dawson , Anthony Scott Muerhoff , Isa K. Mushahwar

发明人： Tami J. Pilot-Matias , Thomas P. Leary , John N. Simons , Robert J. Carrick , Teresa K. Surowy , Suresh M. Desai , George J. Dawson , Anthony Scott Muerhoff , Isa K. Mushahwar

IPC分类号： G01N33/53 , A61K38/00 , A61K39/00 , A61K39/29 , A61P31/12 , C07H21/02 , C07H21/04 , C07K14/02 , C07K14/08 , C07K14/10 , C07K14/18 , C07K16/00 , C07K16/10 , C07K19/00 , C12N15/02 , C12N15/09 , C12N15/40 , C12P21/02 , C12P21/08 , C12Q1/70 , C12R1/91 , G01N33/536 , G01N33/569 , G01N33/576 , G01N33/577 , C12N15/00

CPC分类号： C07K14/005 , C12Q1/707 , G01N33/576 , G01N33/5767 , A61K38/00 , A61K39/00 , C07K2319/00 , C12N2770/24222 , C12N2770/36022 , Y10S530/826

摘要： Recombinantly produced hepatitis GB Virus (HGBV) amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV amino acid sequences and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV recombinantly produced amino acid sequences.

摘要翻译： 用于各种诊断和治疗应用的重组产生的乙型肝炎病毒（HGBV）氨基酸序列，使用特异性结合HGBV的HGBV氨基酸序列和抗体的试剂盒。还提供了从HGBV重组产生的氨基酸序列产生抗体，多克隆或单克隆抗体的方法。

8.

发明授权
Detection of hepatitis GB virus genotypes 失效
标题翻译：检测肝炎病毒基因型

公开(公告)号：US5807670A

公开(公告)日：1998-09-15

申请号：US580038

申请日：1995-12-21

申请人： Anthony Scott Muerhoff , John N. Simons , Thomas P. Leary , Larry Birkenmeyer , James C. Erker , Michelle Chalmers , George J. Dawson , Suresh M. Desai , Isa K. Mushahwar

发明人： Anthony Scott Muerhoff , John N. Simons , Thomas P. Leary , Larry Birkenmeyer , James C. Erker , Michelle Chalmers , George J. Dawson , Suresh M. Desai , Isa K. Mushahwar

IPC分类号： G01N33/566 , C07K14/18 , C12N15/09 , C12N15/113 , C12N15/86 , C12Q1/70 , G01N33/576

CPC分类号： C12N15/1131 , C07K14/005 , C12N15/86 , C12Q1/707 , C07K2319/00 , C12N2310/315 , C12N2310/3181 , C12N2310/33 , C12N2770/24222 , C12N2840/203 , C12Q1/6813

摘要： HGBV-C oligonucleotides from the 5' end of HGBV-C useful for the detection and genotyping of HGBV-C isolates. Also provided are assays which utilize these oligonucleotides.

摘要翻译： 来自HGBV-C的5'端的HGBV-C寡核苷酸可用于HGBV-C分离物的检测和基因分型。还提供了利用这些寡核苷酸的测定法。

9.

发明授权
Nucleic acid detection of hepatitis GB virus 失效
标题翻译：肝炎病毒核酸检测

公开(公告)号：US5709997A

公开(公告)日：1998-01-20

申请号：US635309

申请日：1996-04-19

申请人： Ronald L. Marshall , Cynthia Jou , John N. Simons , Thomas P. Leary , A. Scott Muerhoff , Suresh M. Desai , Isa K. Mushahwar

发明人： Ronald L. Marshall , Cynthia Jou , John N. Simons , Thomas P. Leary , A. Scott Muerhoff , Suresh M. Desai , Isa K. Mushahwar

IPC分类号： C12N15/09 , C12N15/00 , C12Q1/68 , C12Q1/70 , C12R1/92 , C07H21/04 , C12P19/34

CPC分类号： C12Q1/707 , C12Q1/686 , Y10S435/81

摘要： Nucleic oligomer probes useful for detection of HGBV in test samples. Also provided are assays which utilize these probes and test kits which contain these oligomer probes.

摘要翻译： 用于检测样品中HGBV的核寡聚体探针。还提供了利用这些探针和包含这些寡聚体探针的测试试剂盒的测定法。

10.

发明授权
Reagents and methods useful for controlling the translation of hepatitis GBV proteins 失效
标题翻译：用于控制肝炎GBV蛋白翻译的试剂和方法

公开(公告)号：US5955318A

公开(公告)日：1999-09-21

申请号：US639857

申请日：1996-04-19

申请人： John N. Simons , Suresh M. Desai , Isa K. Mushahwar

发明人： John N. Simons , Suresh M. Desai , Isa K. Mushahwar

IPC分类号： C12N15/09 , C07K14/08 , C07K14/18 , C12N15/113 , C12N15/86 , C12Q1/68 , C12Q1/70 , G01N33/566 , G01N33/576 , C12P21/02 , C07H21/02 , C07H21/04

CPC分类号： C12N15/1131 , C07K14/005 , C12N15/86 , C12Q1/707 , C07K2319/00 , C12N2310/315 , C12N2310/3181 , C12N2310/33 , C12N2770/24222 , C12N2840/203 , C12N2840/55 , C12Q1/6813

摘要： Reagents and composition for controlling the translation of hepatitis GB virus (HGBV)-A, -B or -C peptides from viral nucleic acid. These reagents and methods comprise control elements of the 5' NTR region of the HGBV-A, -B, or -C viral genome.

摘要翻译： 用于控制来自病毒核酸的乙型肝炎病毒（HGBV）-A，-B或-C肽的翻译的试剂和组合物。这些试剂和方法包括HGBV-A，-B或-C病毒基因组的5'NTR区的控制元件。

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