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公开(公告)号：US20140296487A1
公开(公告)日：2014-10-02
申请号：US14088328
申请日：2013-11-22
申请人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
发明人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
IPC分类号： C07K14/47
CPC分类号： C07K14/47 , A61K38/00 , C07K14/765 , C07K19/00 , C07K2319/00
摘要： Modified human plasma polypeptides or Fc and uses thereof are provided.
摘要翻译： 提供了修饰的人血浆多肽或Fc及其用途。
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公开(公告)号：US20120041180A1
公开(公告)日：2012-02-16
申请号：US13184889
申请日：2011-07-18
申请人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
发明人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
IPC分类号： C07K19/00
CPC分类号： C07K14/47 , A61K38/00 , C07K14/765 , C07K19/00 , C07K2319/00
摘要： Modified human plasma polypeptides or Fc and uses thereof are provided.
摘要翻译： 提供了修饰的人血浆多肽或Fc及其用途。
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公开(公告)号：US20080125574A1
公开(公告)日：2008-05-29
申请号：US11927139
申请日：2007-10-29
申请人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
发明人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
IPC分类号： C07K14/435 , C07K14/62 , C07K14/575
CPC分类号： C07K14/47 , A61K38/00 , C07K14/765 , C07K19/00 , C07K2319/00
摘要： Modified human plasma polypeptides or Fc and uses thereof are provided.
摘要翻译： 提供了修饰的人血浆多肽或Fc及其用途。
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公开(公告)号：US20080113412A1
公开(公告)日：2008-05-15
申请号：US11927283
申请日：2007-10-29
申请人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
发明人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
CPC分类号： C07K14/47 , A61K38/00 , C07K14/765 , C07K19/00 , C07K2319/00
摘要： Modified human plasma polypeptides or Fc and uses thereof are provided.
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公开(公告)号：US20120190827A1
公开(公告)日：2012-07-26
申请号：US13208136
申请日：2011-08-11
申请人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
发明人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
IPC分类号： C07K16/00
CPC分类号： C07K14/47 , A61K38/00 , C07K14/765 , C07K19/00 , C07K2319/00
摘要： Modified human plasma polypeptides or Fc and uses thereof are provided.
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公开(公告)号：US20110207914A1
公开(公告)日：2011-08-25
申请号：US13035719
申请日：2011-02-25
申请人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
发明人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
IPC分类号： C07K14/435
CPC分类号： C07K14/47 , A61K38/00 , C07K14/765 , C07K19/00 , C07K2319/00
摘要： Modified human plasma polypeptides or Fc and uses thereof are provided.
摘要翻译： 提供了修饰的人血浆多肽或Fc及其用途。
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公开(公告)号：US20080113411A1
公开(公告)日：2008-05-15
申请号：US11927247
申请日：2007-10-29
申请人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
发明人： Joseph SHEFFER , Thea NORMAN , Richard D. DIMARCHI , Anna-Maria A. HAYS PUTNAM , Feng TIAN , Stephanie CHU , Denise KRAWITZ , Ho Sung CHO
CPC分类号： C07K14/47 , A61K38/00 , C07K14/765 , C07K19/00 , C07K2319/00
摘要： Modified human plasma polypeptides or Fc and uses thereof are provided.
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公开(公告)号：US20100035812A1
公开(公告)日：2010-02-11
申请号：US12507237
申请日：2009-07-22
申请人： Anna-Maria A. HAYS PUTNAM , Nick KNUDSEN , Thea NORMAN , Alan KODER , Vadim KRAYNOV , Lillian HO , Peter C. CANNING
发明人： Anna-Maria A. HAYS PUTNAM , Nick KNUDSEN , Thea NORMAN , Alan KODER , Vadim KRAYNOV , Lillian HO , Peter C. CANNING
CPC分类号： C07K14/535 , A61K38/193
摘要： Modified bovine G-CSF polypeptides and uses thereof are provided.
摘要翻译： 提供了改良的牛G-CSF多肽及其用途。
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9.发明申请公开(公告)号：US20080153979A1
公开(公告)日：2008-06-26
申请号：US11873347
申请日：2007-10-16
申请人： Zhenwei MIAO , Junjie LIU , Thea NORMAN , Russell DRIVER
发明人： Zhenwei MIAO , Junjie LIU , Thea NORMAN , Russell DRIVER
IPC分类号： C08G65/02 , C08F26/06 , C08F16/00 , C08F20/56 , C08F20/10 , C07K2/00 , C08B37/00 , C08B37/08 , C08B30/00 , C07K14/76 , C08F16/06
CPC分类号： C07C225/10 , A61K31/198 , A61K38/17 , A61K47/08 , A61K47/10 , A61K47/34 , A61K47/60 , C07C229/36 , C07C237/32 , C07C251/28 , C07C251/54 , C07C251/60 , C07C251/86 , C07C323/63 , C07C2601/08 , C07D209/38 , C07D209/46 , C07D307/83 , C07D307/88 , C07D307/89 , C07D317/22 , C07D317/26 , C07D317/28 , C07D317/30 , C07D333/72 , C07K14/61 , C12P21/02 , G01N33/5008 , G01N33/68 , G01N33/6848 , G01N2500/00 , Y02A50/473 , Y02P20/55
摘要： Disclosed herein are non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The non-natural amino acids, by themselves or as a part of a polypeptide, can include a wide range of possible functionalities, but typical have at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Also disclosed herein are non-natural amino acid polypeptides that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such polypeptides. Typically, the modified non-natural amino acid polypeptides include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Further disclosed are methods for using such non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, including therapeutic, diagnostic, and other biotechnology uses.
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10.发明申请公开(公告)号：US20080268518A1
公开(公告)日：2008-10-30
申请号：US11925662
申请日：2007-10-26
申请人： Zhenwei MIAO , Junjie LIU , Thea NORMAN , Russell DRIVER
发明人： Zhenwei MIAO , Junjie LIU , Thea NORMAN , Russell DRIVER
IPC分类号： C12N9/04 , C07C229/00 , C07D209/04 , C07D317/10 , C07D307/77 , C07K2/00 , C07K14/00 , C12N9/14 , C07K16/00 , C12N9/00 , C07H21/00 , C12N1/00 , C12N7/00
CPC分类号： C07C225/10 , A61K31/198 , A61K38/17 , A61K47/08 , A61K47/10 , A61K47/34 , A61K47/60 , C07C229/36 , C07C237/32 , C07C251/28 , C07C251/54 , C07C251/60 , C07C251/86 , C07C323/63 , C07C2601/08 , C07D209/38 , C07D209/46 , C07D307/83 , C07D307/88 , C07D307/89 , C07D317/22 , C07D317/26 , C07D317/28 , C07D317/30 , C07D333/72 , C07K14/61 , C12P21/02 , G01N33/5008 , G01N33/68 , G01N33/6848 , G01N2500/00 , Y02A50/473 , Y02P20/55
摘要： Disclosed herein are non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The non-natural amino acids, by themselves or as a part of a polypeptide, can include a wide range of possible functionalities, but typical have at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Also disclosed herein are non-natural amino acid polypeptides that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such polypeptides. Typically, the modified non-natural amino acid polypeptides include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Further disclosed are methods for using such non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, including therapeutic, diagnostic, and other biotechnology uses.
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