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公开(公告)号：US07955343B2
公开(公告)日：2011-06-07
申请号：US11924758
申请日：2007-10-26
申请人： Joshua Makower , J. Christopher Flaherty , Timothy Machold , Jason Whitt , Philip Evard , Patrick Macaulay , John Garibotto , Marc Jensen
发明人： Joshua Makower , J. Christopher Flaherty , Timothy Machold , Jason Whitt , Philip Evard , Patrick Macaulay , John Garibotto , Marc Jensen
IPC分类号： A61B17/34
CPC分类号： A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B17/12186 , A61B17/1219 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/0641 , A61B2017/0647 , A61B2017/0649 , A61B2017/1107 , A61B2017/1139 , A61B2017/1205 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/075 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/0096 , A61M2025/1052
摘要： Methods and apparatus for occluding blood flow within a blood vessel. In a first series of embodiments, the present invention comprises a plurality of embolic devices deployable through the lumen of a conventional catheter such that when deployed, said embolic devices remain resident and occlude blood flow at a specific site within the lumen of the blood vessel. Such embolic devices comprise either mechanical embolic devices that become embedded within or compress against the lumen of the vessel or chemical vaso-occlusive agents that seal off blood flow at a given site. A second embodiment of the present invention comprises utilization of a vacuum/cauterizing device capable of sucking in the lumen of the vessel about the device to maintain the vessel in a closed condition where there is then applied a sufficient amount of energy to cause the tissue collapsed about the device to denature into a closure. In a third series of embodiments, the present invention comprises the combination of an embolization facilitator coupled with the application of an energy force to form an intraluminal closure at a specified site within a vessel.
摘要翻译： 阻塞血管内血流的方法和装置。 在第一系列实施例中，本发明包括可以通过常规导管的内腔部署的多个栓塞装置，使得当展开时，所述栓塞装置保持驻留并阻塞在血管腔内的特定部位处的血流。 这种栓塞装置包括机械栓塞装置，其嵌入或压缩容器的内腔或封闭给定部位的血流的化学血管闭塞剂。 本发明的第二个实施方案包括使用能够吸收容器内腔的设备的真空/烧灼装置，以将容器保持在闭合状态，在那里然后施加足够量的能量以使组织折叠 关于器件变性成闭合。 在第三系列实施方案中，本发明包括栓塞促进剂与施加能量力的组合，以在血管内的指定部位形成腔内闭合。
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公开(公告)号：US20080045996A1
公开(公告)日：2008-02-21
申请号：US11924758
申请日：2007-10-26
申请人： Joshua Makower , J. Christopher Flaherty , Timothy Machold , Jason Whitt , Philip Evard , Patrick Macaulay , John Garibotto , Marc Jensen
发明人： Joshua Makower , J. Christopher Flaherty , Timothy Machold , Jason Whitt , Philip Evard , Patrick Macaulay , John Garibotto , Marc Jensen
IPC分类号： A61M29/02
CPC分类号： A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B17/12186 , A61B17/1219 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/0641 , A61B2017/0647 , A61B2017/0649 , A61B2017/1107 , A61B2017/1139 , A61B2017/1205 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/075 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/0096 , A61M2025/1052
摘要： Methods and apparatus for occluding blood flow within a blood vessel. In a first series of embodiments, the present invention comprises a plurality of embolic devices deployable through the lumen of a conventional catheter such that when deployed, said embolic devices remain resident and occlude blood flow at a specific site within the lumen of the blood vessel. Such embolic devices comprise either mechanical embolic devices that become embedded within or compress against the lumen of the vessel or chemical vaso-occlusive agents that seal off blood flow at a given site. A second embodiment of the present invention comprises utilization of a vacuum/cauterizing device capable of sucking in the lumen of the vessel about the device to maintain the vessel in a closed condition where there is then applied a sufficient amount of energy to cause the tissue collapsed about the device to denature into a closure. In a third series of embodiments, the present invention comprises the combination of an embolization facilitator coupled with the application of an energy force to form an intraluminal closure at a specified site within a vessel.
摘要翻译： 阻塞血管内血流的方法和装置。 在第一系列实施例中，本发明包括可以通过常规导管的内腔部署的多个栓塞装置，使得当展开时，所述栓塞装置保持驻留并且阻塞在血管腔内的特定位置处的血流。 这种栓塞装置包括机械栓塞装置，其嵌入或压缩容器的内腔或封闭给定部位的血流的化学血管闭塞剂。 本发明的第二个实施方案包括使用能够吸收容器内腔的设备的真空/烧灼装置，以将容器保持在闭合状态，在那里然后施加足够量的能量以使组织折叠 关于器件变性成闭合。 在第三系列实施方案中，本发明包括栓塞促进剂与施加能量力的组合，以在血管内的指定部位形成腔内闭合。
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公开(公告)号：US06379319B1
公开(公告)日：2002-04-30
申请号：US09179737
申请日：1998-10-27
申请人： John Garibotto , Steven W. Kim , Jason Whitt , J. Christopher Flaherty , Joshua Makower , Motoya Hayase , John Chang
发明人： John Garibotto , Steven W. Kim , Jason Whitt , J. Christopher Flaherty , Joshua Makower , Motoya Hayase , John Chang
IPC分类号： A61B500
CPC分类号： A61B17/11 , A61B17/00491 , A61B17/0643 , A61B17/12022 , A61B17/12109 , A61B17/12136 , A61B17/221 , A61B17/32056 , A61B17/3417 , A61B18/00 , A61B18/1492 , A61B90/39 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/22035 , A61B2017/22094 , A61B2017/2212 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61F2/064 , A61F2/07 , A61F2/90 , A61F2002/061 , A61F2002/30079 , A61F2002/825 , A61F2210/009 , A61M25/0105 , A61M25/0133 , A61M2025/0076 , A61M2025/0161 , A61M2025/1052
摘要： Devices and methods for achieving directed placement of guidewires or other flexible rails over which other catheters or other devices may be introduced to a targeted location. A guidewire directing device includes a lumen extending between a proximal end and a distal peripheral opening for directing a guidewire laterally from the device, and may have a deflecting member with a predetermined deflection angle in the lumen adjacent the peripheral opening. A snaring device is also provided that includes one or more lumens through which a snare or other grasping member is directed for releasably capturing or coupling to a guidewire. The snaring and target guidewire devices may include cooperating end effectors for releasably coupling or securing the devices together. The devices may be used for directing, snaring and/or manipulating one or more guidewires between two blood vessels connected by an interstitial channel, for example, to “floss” a guidewire through the coronary arterial and venous systems between two percutaneous entry sites and/or to bypass a lesion in a vessel using proximal and distal interstitial channels communicating with an adjacent vessel.
摘要翻译： 用于实现导线或其它柔性导轨的定向放置的装置和方法，其它导管或其它装置可以通过其引导到目标位置。 导丝引导装置包括在近端和远侧外围开口之间延伸的腔，用于将导丝从装置横向引导，并且可具有在邻近周边开口的内腔中具有预定偏转角的偏转构件。 还提供了一种包围一个或多个腔的扼流装置，一个圈套或其他把持件被引导通过该腔，用于可释放地捕获或连接到导丝。 牵引和目标导丝装置可以包括用于可释放地将装置连接或固定在一起的协作的端部执行器。 这些装置可用于引导，扼制和/或操纵通过间质通道连接的两个血管之间的一个或多个导线，例如通过两个经皮进入部位之间的冠状动脉和静脉系统“引导”导丝，和/ 或绕过与相邻血管连通的近端和远端间隙通道的血管中的病变。
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公开(公告)号：US07316655B2
公开(公告)日：2008-01-08
申请号：US10136929
申请日：2002-04-30
申请人： John Garibotto , Steven W. Kim , Jason Whitt , J. Christopher Flaherty , Joshua Makower , Motoya Hayase , John Chang
发明人： John Garibotto , Steven W. Kim , Jason Whitt , J. Christopher Flaherty , Joshua Makower , Motoya Hayase , John Chang
CPC分类号： A61B17/11 , A61B17/00491 , A61B17/0643 , A61B17/12022 , A61B17/12109 , A61B17/12136 , A61B17/221 , A61B17/32056 , A61B17/3417 , A61B18/00 , A61B18/1492 , A61B90/39 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/22035 , A61B2017/22094 , A61B2017/2212 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61F2/064 , A61F2/07 , A61F2/90 , A61F2002/061 , A61F2002/30079 , A61F2002/825 , A61F2210/009 , A61M25/0105 , A61M25/0133 , A61M2025/0076 , A61M2025/0161 , A61M2025/1052
摘要： Devices and methods for achieving directed placement of guidewires or other flexible rails over which other catheters or other devices may be introduced to a targeted location. A guidewire directing device includes a lumen extending between a proximal end and a distal peripheral opening for directing a guidewire laterally from the device, and may have a deflecting member with a predetermined deflection angle in the lumen adjacent the peripheral opening. A snaring device is also provided that includes one or more lumens through which a snare or other grasping member is directed for releasably capturing or coupling to a guidewire. The snaring and target guidewire devices may include cooperating end effectors for releasably coupling or securing the devices together. The devices may be used for directing, snaring and/or manipulating one or more guidewires between two blood vessels connected by an interstitial channel, for example, to “floss” a guidewire through the coronary arterial and venous systems between two percutaneous entry sites and/or to bypass a lesion in a vessel using proximal and distal interstitial channels communicating with an adjacent vessel.
摘要翻译： 用于实现导线或其它柔性导轨的定向放置的装置和方法，其它导管或其它装置可以通过其引导到目标位置。 导丝引导装置包括在近端和远侧外围开口之间延伸的腔，用于将导丝从装置横向引导，并且可具有在邻近周边开口的内腔中具有预定偏转角的偏转构件。 还提供了一种包围一个或多个腔的扼流装置，一个圈套或其他把持件被引导通过该腔，用于可释放地捕获或连接到导丝。 牵引和目标导丝装置可以包括用于可释放地将装置连接或固定在一起的协作的端部执行器。 这些装置可用于引导，扼制和/或操纵通过间质通道连接的两个血管之间的一个或多个导线，例如通过两个经皮进入部位之间的冠状动脉和静脉系统“引导”导丝，和/ 或绕过与相邻血管连通的近端和远端间隙通道的血管中的病变。
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5.发明申请Systems and Methods for Delivering Drugs to Selected Locations Within the Body 有权将药物运送到体内所选位置的系统和方法公开(公告)号：US20100324471A1
公开(公告)日：2010-12-23
申请号：US12715252
申请日：2010-03-01
申请人： J. Christopher Flaherty , Joshua Makower , Philip Evard , Patrick E. MacAulay , Jason B. Whitt , Robert C. Colloton , K. Angela Macfarlane
发明人： J. Christopher Flaherty , Joshua Makower , Philip Evard , Patrick E. MacAulay , Jason B. Whitt , Robert C. Colloton , K. Angela Macfarlane
CPC分类号： A61M25/0084 , A61B8/12 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61B17/22 , A61B17/3417 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22077 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61F2/2493 , A61F2002/30079 , A61F2210/009 , A61M5/007 , A61M5/46 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M25/0108 , A61M39/0208 , A61M39/04 , A61M2025/0037 , A61M2025/0076 , A61M2025/0086 , A61M2025/0087 , A61M2025/009 , A61M2025/0096 , A61M2025/1052
摘要： A transvascular system for delivering a drug to a tissue region from a blood vessel includes a catheter having a distal portion with puncturing, orientation, drug delivery, and imaging elements. The puncturing element is deployable for penetrating the vessel wall to access the tissue region. The orientation element has a predetermined relationship with the puncturing element, the imaging element detecting the location of the orientation element with respect to the tissue region to orient the puncturing element. The catheter is percutaneously introduced into the vessel, the puncturing element is oriented towards the tissue region, the puncturing element is deployed to access the tissue region, and the drug is delivered to the tissue region. An ablation device may also be deployed to create a cavity or fluid reservoir in the tissue region for receiving the drug therein, or an indwelling catheter may be advanced into and left in the tissue region.
摘要翻译： 用于将药物从血管输送到组织区域的经血管系统包括具有穿刺，取向，药物递送和成像元件的远侧部分的导管。 穿刺元件可展开以穿透血管壁以进入组织区域。 定向元件与穿刺元件具有预定的关系，成像元件检测取向元件相对于组织区域的位置以定向穿刺元件。 将导管经皮引入容器中，穿刺元件朝向组织区域定向，穿刺元件展开以接近组织区域，并将药物递送至组织区域。 还可以部署消融装置以在组织区域中形成用于在其中接收药物的空腔或流体储存器，或者留置导管可以进入组织区域并留在组织区域中。
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6.发明授权公开(公告)号：US07159592B1
公开(公告)日：2007-01-09
申请号：US09710332
申请日：2000-11-09
申请人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Margaret W. Tumas , Theodore C. Lamson , Marc Jensen
发明人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Margaret W. Tumas , Theodore C. Lamson , Marc Jensen
IPC分类号： A61B19/00
CPC分类号： A61B17/00234 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12131 , A61B17/12136 , A61B17/12172 , A61B17/3417 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139 , A61B2017/12127 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61F2/07 , A61F2/2412 , A61F2/2418 , A61F2/2421 , A61F2/2475 , A61F2/2493 , A61F2/90 , A61F2/94 , A61F2002/30079 , A61F2210/009 , A61F2220/0008 , A61M39/24 , A61M2025/0076 , A61M2025/1052
摘要： Methods and apparatus for direct coronary revascularization wherein a transmyocardial passageway is formed between a chamber of the heart and a coronary blood vessel to permit blood to flow therebetween. In some embodiments, the transmyocardial passageway is formed between a chamber of the heart and a coronary vein. The invention includes unstented transmyocardial passageways, as well as transmyocardial passageways wherein protrusive stent devices extend from the transmyocardial passageway into an adjacent coronary vessel or chamber of the heart. The apparatus of the present invention include protrusive stent devices for stenting of transmyocardial passageways, intraluminal valving devices for valving of transmyocardial passageways, intracardiac valving devices for valving of transmyocardial passageways, endogenous tissue valves for valving of transmyocardial passageways, and ancillary apparatus for use in conjunction therewith.
摘要翻译： 用于直接冠状动脉血运重建的方法和装置，其中在心脏室与冠状血管之间形成经心肌通道以允许血液在其间流动。 在一些实施例中，在心脏室和冠状静脉之间形成经心肌通路。 本发明包括不连续的经心肌通道以及经心肌通道，其中突出的支架装置从心肌通道延伸到相邻的心脏的冠状血管或腔室。 本发明的装置包括用于跨心肌通道支架的突出支架装置，用于跨心肌通道的阀门的腔内瓣膜装置，用于跨心肌通道的阀门的心脏内瓣膜装置，用于跨心肌通道的阀门的内源性组织瓣膜以及用于联合的辅助装置 随之而来。
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公开(公告)号：US06638293B1
公开(公告)日：2003-10-28
申请号：US09117516
申请日：1999-01-21
申请人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason B. Whitt , Philip C. Evard , Patrick E. Macaulay , John T. Garibotto , Marc Jensen
发明人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason B. Whitt , Philip C. Evard , Patrick E. Macaulay , John T. Garibotto , Marc Jensen
IPC分类号： A61M2900
CPC分类号： A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B17/12186 , A61B17/1219 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/0641 , A61B2017/0647 , A61B2017/0649 , A61B2017/1107 , A61B2017/1139 , A61B2017/1205 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/075 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/0096 , A61M2025/1052
摘要： This invention is methods and apparatus for occluding blood flow within a blood vessel (22). In a first series of embodiments, the present invention comprises a plurality of embolic devices (16) deployable through the lumen (12) of a conventional catheter (10) such that when deployed, said embolic devices (16) remain resident and occlude blood flow at a specific site within the lumen of the blood vessel (22). Such embolic devices (16) comprise either mechanical embolic devices that become embedded within or compress against the lumen of the vessel or chemical vaso occlusive agents that seal off blood flow at a given site. A second embodiment of the present invention comprises utilization of a vacuum/cauterizing device capable of sucking in the lumen of the vessel about the device to maintain the vessel in a closed condition where there is then applied a sufficient amount of energy to cause the tissue collapsed about the device to denature into a closure. In a third series of embodiments, the present invention comprises the combination of an embolization facilitator coupled with the application of an energy force to form an intraluminal closure at a specified site within a vessel.
摘要翻译： 本发明是用于阻塞血管内血流的方法和装置（22）。 在第一系列实施例中，本发明包括可以通过常规导管（10）的内腔（12）展开的多个栓塞装置（16），使得当展开时，所述栓塞装置（16）保持驻留并阻塞血流 在血管（22）的内腔内的特定部位。 这种栓塞装置（16）包括机械栓塞装置，其嵌入或压缩在容器的内腔或封闭给定部位的血液流动的化学血管闭塞剂。 本发明的第二个实施方案包括使用能够吸收容器内腔的设备的真空/烧灼装置，以将容器保持在闭合状态，在那里然后施加足够量的能量以使组织折叠 关于器件变性成闭合。 在第三系列实施方案中，本发明包括栓塞促进剂与施加能量力的组合，以在血管内的指定部位形成腔内闭合。
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8.发明授权公开(公告)号：US07849860B2
公开(公告)日：2010-12-14
申请号：US11343936
申请日：2006-01-30
申请人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Margaret W. Tumas , Theodore C. Lamson , Marc Jensen
发明人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Margaret W. Tumas , Theodore C. Lamson , Marc Jensen
IPC分类号： A61B17/00
CPC分类号： A61B17/00234 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12131 , A61B17/12136 , A61B17/12172 , A61B17/3417 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139 , A61B2017/12127 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61F2/07 , A61F2/2412 , A61F2/2418 , A61F2/2421 , A61F2/2475 , A61F2/2493 , A61F2/90 , A61F2/94 , A61F2002/30079 , A61F2210/009 , A61F2220/0008 , A61M39/24 , A61M2025/0076 , A61M2025/1052
摘要： Methods and apparatus for direct coronary revascularization wherein a transmyocardial passageway is formed between a chamber of the heart and a coronary blood vessel to permit blood to flow therebetween. In some embodiments, the transmyocardial passageway is formed between a chamber of the heart and a coronary vein. The invention includes unstented transmyocardial passageways, as well as transmyocardial passageways wherein protrusive stent devices extend from the transmyocardial passageway into an adjacent coronary vessel or chamber of the heart. The apparatus of the present invention include protrusive stent devices for stenting of transmyocardial passageways, intraluminal valving devices for valving of transmyocardial passageways, intracardiac valving devices for valving of transmyocardial passageways, endogenous tissue valves for valving of transmyocardial passageways, and ancillary apparatus for use in conjunction therewith.
摘要翻译： 用于直接冠状动脉血运重建的方法和装置，其中在心脏室与冠状血管之间形成经心肌通道以允许血液在其间流动。 在一些实施例中，在心脏室和冠状静脉之间形成经心肌通路。 本发明包括不连续的经心肌通道以及经心肌通道，其中突出的支架装置从心肌通道延伸到相邻的心脏的冠状血管或腔室。 本发明的装置包括用于跨心肌通道支架的突出支架装置，用于跨心肌通道的阀门的腔内瓣膜装置，用于跨心肌通道的阀门的心脏内瓣膜装置，用于跨心肌通道的阀门的内源性组织瓣膜以及用于联合的辅助装置 随之而来。
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9.发明授权公开(公告)号：US06929009B2
公开(公告)日：2005-08-16
申请号：US10150306
申请日：2002-05-16
申请人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Margaret W. Tumas , Theodore C. Lamson , Marc Jensen
发明人： Joshua Makower , J. Christopher Flaherty , Timothy R. Machold , Jason Brian Whitt , Margaret W. Tumas , Theodore C. Lamson , Marc Jensen
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , A61B17/12 , A61B17/30 , A61B17/34 , A61B18/00 , A61B18/14 , A61B19/00 , A61F2/00 , A61F2/02 , A61F2/24 , A61F2/90 , A61F2/94 , A61L27/00 , A61M25/00 , A61M39/24
CPC分类号： A61B17/00234 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12131 , A61B17/12136 , A61B17/12172 , A61B17/3417 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139 , A61B2017/12127 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61F2/07 , A61F2/2412 , A61F2/2418 , A61F2/2421 , A61F2/2475 , A61F2/2493 , A61F2/90 , A61F2/94 , A61F2002/30079 , A61F2210/009 , A61F2220/0008 , A61M39/24 , A61M2025/0076 , A61M2025/1052
摘要： Methods and apparatus for direct coronary revascularization wherein a transmyocardial passageway is formed between a chamber of the heart and a coronary blood vessel to permit blood to flow therebetween. In some embodiments, the transmyocardial passageway is formed between a chamber of the heart and a coronary vein. The invention includes unstented transmyocardial passageways, as well as transmyocardial passageways wherein protrusive stent devices extend from the transmyocardial passageway into an adjacent coronary vessel or chamber of the heart. The apparatus of the present invention include protrusive stent devices for stenting of transmyocardial passageways, intraluminal valving devices for valving of transmyocardial passageways, intracardiac valving devices for valving of transmyocardial passageways, endogenous tissue valves for valving of transmyocardial passageways, and ancillary apparatus for use in conjunction therewith.
摘要翻译： 用于直接冠状动脉血运重建的方法和装置，其中在心脏室与冠状血管之间形成经心肌通道以允许血液在其间流动。 在一些实施例中，在心脏室和冠状静脉之间形成经心肌通路。 本发明包括不连续的经心肌通道以及经心肌通道，其中突出的支架装置从心肌通道延伸到相邻的心脏的冠状血管或腔室。 本发明的装置包括用于跨心肌通道支架的突出支架装置，用于跨心肌通道的阀门的腔内瓣膜装置，用于跨心肌通道的阀门的心脏内瓣膜装置，用于跨心肌通道的阀门的内源性组织瓣膜以及用于联合的辅助装置 随之而来。
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公开(公告)号：US08585596B1
公开(公告)日：2013-11-19
申请号：US10370429
申请日：2003-02-20
申请人： J. Christopher Flaherty , Jason B. Whitt , Patrick E. Macaulay , David R. Tholfsen , John T. Garibotto , Philip C. Evard , Joshua Makower
发明人： J. Christopher Flaherty , Jason B. Whitt , Patrick E. Macaulay , David R. Tholfsen , John T. Garibotto , Philip C. Evard , Joshua Makower
IPC分类号： A61B8/00 , A61M25/098
CPC分类号： A61M25/0108 , A61B17/22 , A61B17/3207 , A61B2017/00252 , A61B2017/00455 , A61B2017/22077 , A61B2090/3784 , A61B2090/3925
摘要： A system of catheter devices and methods for forming channels or passageways between a luminal anatomical structure (e.g., a blood vessel) and a target location (e.g., another blood vessel, an organ, a mass of tissue, etc.) for the purpose of rerouting blood flow or for delivering a substance or instrument, etc. to the target location.
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