公开(公告)号：US08585596B1

公开(公告)日：2013-11-19

申请号：US10370429

申请日：2003-02-20

申请人： J. Christopher Flaherty ,  Jason B. Whitt ,  Patrick E. Macaulay ,  David R. Tholfsen ,  John T. Garibotto ,  Philip C. Evard ,  Joshua Makower

发明人： J. Christopher Flaherty ,  Jason B. Whitt ,  Patrick E. Macaulay ,  David R. Tholfsen ,  John T. Garibotto ,  Philip C. Evard ,  Joshua Makower

IPC分类号： A61B8/00 ,  A61M25/098

CPC分类号： A61M25/0108 ,  A61B17/22 ,  A61B17/3207 ,  A61B2017/00252 ,  A61B2017/00455 ,  A61B2017/22077 ,  A61B2090/3784 ,  A61B2090/3925

摘要： A system of catheter devices and methods for forming channels or passageways between a luminal anatomical structure (e.g., a blood vessel) and a target location (e.g., another blood vessel, an organ, a mass of tissue, etc.) for the purpose of rerouting blood flow or for delivering a substance or instrument, etc. to the target location.

公开(公告)号：US20110224596A1

公开(公告)日：2011-09-15

申请号：US13114987

申请日：2011-05-24

申请人： J Christopher Flaherty ,  Jason B. Whitt ,  John Y. Chang ,  David R. Tholfsen ,  Philip C. Evard ,  Joshua Makower

发明人： J Christopher Flaherty ,  Jason B. Whitt ,  John Y. Chang ,  David R. Tholfsen ,  Philip C. Evard ,  Joshua Makower

IPC分类号： A61M1/00

CPC分类号： A61B17/3403 ,  A61B1/3137 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4488 ,  A61B17/11 ,  A61B17/12109 ,  A61B17/12172 ,  A61B17/3207 ,  A61B17/320725 ,  A61B17/3417 ,  A61B17/3496 ,  A61B18/00 ,  A61B18/1445 ,  A61B18/1477 ,  A61B18/1492 ,  A61B18/24 ,  A61B90/361 ,  A61B90/39 ,  A61B90/40 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/003 ,  A61B2017/00455 ,  A61B2017/00504 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61B2017/12127 ,  A61B2017/22038 ,  A61B2017/22069 ,  A61B2017/22072 ,  A61B2017/22077 ,  A61B2017/306 ,  A61B2017/347 ,  A61B2017/3488 ,  A61B2018/00392 ,  A61B2018/00869 ,  A61B2018/1425 ,  A61B2090/378 ,  A61B2090/3784 ,  A61B2090/3925 ,  A61B2090/3929 ,  A61B2090/3958 ,  A61F2/07 ,  A61F2/2493 ,  A61F2/90 ,  A61F2/95 ,  A61F2002/30079 ,  A61F2002/8486 ,  A61F2210/009 ,  A61K31/195 ,  A61M25/0133 ,  A61M25/0152 ,  A61M29/00 ,  A61M29/02 ,  A61M2025/0076 ,  A61M2025/018 ,  A61M2025/1052

摘要： A catheter device that is useable to penetrate from a blood vessel in which the catheter device is positioned to a target location comprises a flexible catheter advanceable into the first blood vessel, a tissue penetrator lumen adapted to receive an operative tissue penetrator which is usable to penetrate from the blood vessel to the target location when properly aimed. Further said catheter including an imaging transducer fixedly mounted on or within the catheter body to provide an imaging signal from which an image of the target location can be obtained. The catheter device may include an imageable marker on the catheter to form on the image obtainable from the imaging signal a penetrator path indication that indicates the path that will be followed by the tissue penetrator when the tissue penetrator exits from the catheter. Alternatively, or addition thereto, the imaging transducer may comprise a plurality of imaging elements which are located so that the penetrator path indication can be obtained. A method of utilizing such a catheter device to bypass an arterial obstruction is also disclosed.

摘要翻译： 可用于从其中导管装置定位到目标位置的血管穿透的导管装置包括可推进到第一血管的柔性导管，适于接收可用于穿透的手术组织穿透器的组织穿透器腔 从正确瞄准的血管到目标位置。 另外所述导管包括固定地安装在导管主体上或导管本体内的成像传感器，以提供成像信号，从该成像信号可以获得目标位置的图像。 导管装置可以包括导管上的可成像标记，以在成像信号上形成图像，该穿透器路径指示指示当组织穿透器从导管离开时将由组织穿透器跟随的路径。 或者，或者除此之外，成像换能器可以包括多个成像元件，其被定位成可以获得穿透器路径指示。 还公开了利用这种导管装置绕过动脉阻塞物的方法。

公开(公告)号：US07094230B2

公开(公告)日：2006-08-22

申请号：US10738226

申请日：2003-12-16

申请人： J. Christopher Flaherty ,  Joshua Makower ,  Philip C. Evard ,  Patrick E. MacAulay ,  Jason B. Whitt ,  Robert C. Colloton ,  K. Angela Macfarlane

发明人： J. Christopher Flaherty ,  Joshua Makower ,  Philip C. Evard ,  Patrick E. MacAulay ,  Jason B. Whitt ,  Robert C. Colloton ,  K. Angela Macfarlane

IPC分类号： A61K9/22 ,  A61M37/00 ,  A61F2/00

CPC分类号： A61M25/0084 ,  A61B8/12 ,  A61B17/00491 ,  A61B17/0643 ,  A61B17/11 ,  A61B17/12022 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/12172 ,  A61B17/22 ,  A61B17/3417 ,  A61B18/00 ,  A61B18/1477 ,  A61B18/1492 ,  A61B90/40 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/00504 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61B2017/12127 ,  A61B2017/22077 ,  A61B2017/306 ,  A61B2017/347 ,  A61B2018/00392 ,  A61B2018/1425 ,  A61F2/2493 ,  A61F2002/30079 ,  A61F2210/009 ,  A61M5/007 ,  A61M5/46 ,  A61M25/0068 ,  A61M25/0069 ,  A61M25/007 ,  A61M25/0108 ,  A61M39/0208 ,  A61M39/04 ,  A61M2025/0037 ,  A61M2025/0076 ,  A61M2025/0086 ,  A61M2025/0087 ,  A61M2025/009 ,  A61M2025/0096 ,  A61M2025/1052

摘要： An implantable reservoir device (400) including an enclosed membrane (408) on an expandable frame (402) that defines a reservoir (410) and includes a porous region (418). The reservoir device (400) may be deployed and expanded within a blood vessel, and may be filled in situ or prefilled with a drug that passes through the porous region (418). Alternatively, a pair of expandable endovascular blockers (500) may be used to isolate a section of a blood vessel which may be filled with a drug that may be absorbed by the surrounding tissue.

摘要翻译： 一种可植入储存器装置（400），其包括限定储存器（410）并且包括多孔区域（418）的可扩张框架（402）上的封闭膜（408）。 储存装置（400）可以在血管内展开和扩张，并且可以在原位填充或预填充穿过多孔区域的药物（418）。 或者，一对可扩张血管内阻滞剂（500）可以用于分离可以被可被周围组织吸收的药物填充的血管的一部分。

公开(公告)号：US06544230B1

公开(公告)日：2003-04-08

申请号：US09282276

申请日：1999-03-31

申请人： J. Christopher Flaherty ,  Jason B. Whitt ,  Patrick E. Macaulay ,  David R. Tholfsen ,  John T. Garibotto ,  Philip C. Evard ,  Joshua Makower

发明人： J. Christopher Flaherty ,  Jason B. Whitt ,  Patrick E. Macaulay ,  David R. Tholfsen ,  John T. Garibotto ,  Philip C. Evard ,  Joshua Makower

IPC分类号： A61M5178

CPC分类号： A61M25/0108 ,  A61B17/22 ,  A61B17/3207 ,  A61B2017/00252 ,  A61B2017/00455 ,  A61B2017/22077 ,  A61B2090/3784 ,  A61B2090/3925

摘要： A system of catheter devices and methods for forming channels or passageways between a luminal anatomical structure (e.g., a blood vessel) and a target location (e.g., another blood vessel, an organ, a mass of tissue, etc.) for the purpose of rerouting blood flow or for delivering a substance or instrument, etc. to the target location.

摘要翻译： 用于在管腔解剖结构（例如，血管）和目标位置（例如另一血管，器官，组织块等）之间形成通道或通道的导管装置和方法的系统，用于 重新路由血液流动或将物质或仪器等传送到目标位置。

公开(公告)号：US20100121357A1

公开(公告)日：2010-05-13

申请号：US12634916

申请日：2009-12-10

申请人： J. Christopher Flaherty ,  Jason B. Whitt ,  John Y. Chang ,  David R. Tholfsen ,  Philip C. Evard ,  Joshua Makower

发明人： J. Christopher Flaherty ,  Jason B. Whitt ,  John Y. Chang ,  David R. Tholfsen ,  Philip C. Evard ,  Joshua Makower

IPC分类号： A61B17/11 ,  A61B17/34

CPC分类号： A61B17/3403 ,  A61B1/3137 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4488 ,  A61B17/11 ,  A61B17/12109 ,  A61B17/12172 ,  A61B17/3207 ,  A61B17/320725 ,  A61B17/3417 ,  A61B17/3496 ,  A61B18/00 ,  A61B18/1445 ,  A61B18/1477 ,  A61B18/1492 ,  A61B18/24 ,  A61B90/361 ,  A61B90/39 ,  A61B90/40 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/003 ,  A61B2017/00455 ,  A61B2017/00504 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61B2017/12127 ,  A61B2017/22038 ,  A61B2017/22069 ,  A61B2017/22072 ,  A61B2017/22077 ,  A61B2017/306 ,  A61B2017/347 ,  A61B2017/3488 ,  A61B2018/00392 ,  A61B2018/00869 ,  A61B2018/1425 ,  A61B2090/378 ,  A61B2090/3784 ,  A61B2090/3925 ,  A61B2090/3929 ,  A61B2090/3958 ,  A61F2/07 ,  A61F2/2493 ,  A61F2/90 ,  A61F2/95 ,  A61F2002/30079 ,  A61F2002/8486 ,  A61F2210/009 ,  A61K31/195 ,  A61M25/0133 ,  A61M25/0152 ,  A61M29/00 ,  A61M29/02 ,  A61M2025/0076 ,  A61M2025/018 ,  A61M2025/1052

摘要： A catheter device that is useable to penetrate from a blood vessel in which the catheter device is positioned to a target location comprises a flexible catheter advanceable into the first blood vessel, a tissue penetrator lumen adapted to receive an operative tissue penetrator which is usable to penetrate from the blood vessel to the target location when properly aimed. Further said catheter including an imaging transducer fixedly mounted on or within the catheter body to provide an imaging signal from which an image of the target location can be obtained. The catheter device may include an imageable marker on the catheter to form on the image obtainable from the imaging signal a penetrator path indication that indicates the path that will be followed by the tissue penetrator when the tissue penetrator exits from the catheter. Alternatively, or addition thereto, the imaging transducer may comprise a plurality of imaging elements which are located so that the penetrator path indication can be obtained. A method of utilizing such a catheter device to bypass an arterial obstruction is also disclosed.

摘要翻译： 可用于从其中导管装置定位到目标位置的血管穿透的导管装置包括可推进到第一血管的柔性导管，适于接收可用于穿透的手术组织穿透器的组织穿透器腔 从正确瞄准的血管到目标位置。 另外所述导管包括固定地安装在导管主体上或导管本体内的成像传感器，以提供成像信号，从该成像信号可以获得目标位置的图像。 导管装置可以包括导管上的可成像标记，以在成像信号上形成图像，该穿透器路径指示指示当组织穿透器从导管离开时将由组织穿透器跟随的路径。 或者，或者除此之外，成像换能器可以包括多个成像元件，其被定位成可以获得穿透器路径指示。 还公开了利用这种导管装置绕过动脉阻塞物的方法。

公开(公告)号：US07637870B2

公开(公告)日：2009-12-29

申请号：US10714155

申请日：2003-11-14

申请人： J. Christopher Flaherty ,  Jason B. Whitt ,  John Y. Chang ,  David R. Tholfsen ,  Philip C. Evard ,  Joshua Makower

发明人： J. Christopher Flaherty ,  Jason B. Whitt ,  John Y. Chang ,  David R. Tholfsen ,  Philip C. Evard ,  Joshua Makower

IPC分类号： A61B8/00 ,  A61B8/14 ,  A61M29/098

CPC分类号： A61B17/3403 ,  A61B1/3137 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4488 ,  A61B17/11 ,  A61B17/12109 ,  A61B17/12172 ,  A61B17/3207 ,  A61B17/320725 ,  A61B17/3417 ,  A61B17/3496 ,  A61B18/00 ,  A61B18/1445 ,  A61B18/1477 ,  A61B18/1492 ,  A61B18/24 ,  A61B90/361 ,  A61B90/39 ,  A61B90/40 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/003 ,  A61B2017/00455 ,  A61B2017/00504 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61B2017/12127 ,  A61B2017/22038 ,  A61B2017/22069 ,  A61B2017/22072 ,  A61B2017/22077 ,  A61B2017/306 ,  A61B2017/347 ,  A61B2017/3488 ,  A61B2018/00392 ,  A61B2018/00869 ,  A61B2018/1425 ,  A61B2090/378 ,  A61B2090/3784 ,  A61B2090/3925 ,  A61B2090/3929 ,  A61B2090/3958 ,  A61F2/07 ,  A61F2/2493 ,  A61F2/90 ,  A61F2/95 ,  A61F2002/30079 ,  A61F2002/8486 ,  A61F2210/009 ,  A61K31/195 ,  A61M25/0133 ,  A61M25/0152 ,  A61M29/00 ,  A61M29/02 ,  A61M2025/0076 ,  A61M2025/018 ,  A61M2025/1052

摘要： A catheter device that is useable to penetrate from a blood vessel in which the catheter device is positioned to a target location comprises a flexible catheter advanceable into the first blood vessel, a tissue penetrator lumen adapted to receive an operative tissue penetrator which is usable to penetrate from the blood vessel to the target location when properly aimed. Further said catheter including an imaging transducer fixedly mounted on or within the catheter body to provide an imaging signal from which an image of the target location can be obtained. The catheter device may include an imageable marker on the catheter to form on the image obtainable from the imaging signal a penetrator path indication that indicates the path that will be followed by the tissue penetrator when the tissue penetrator exits from the catheter. Alternatively, or addition thereto, the imaging transducer may comprise a plurality of imaging elements which are located so that the penetrator path indication can be obtained. A method of utilizing such a catheter device to bypass an arterial obstruction is also disclosed.

公开(公告)号：US5916193A

公开(公告)日：1999-06-29

申请号：US694916

申请日：1996-11-30

申请人： John H. Stevens ,  Jeffrey W. Krier ,  Kirsten L. Valley ,  Philip C. Evard

发明人： John H. Stevens ,  Jeffrey W. Krier ,  Kirsten L. Valley ,  Philip C. Evard

IPC分类号： A61F2/24 ,  A61F2/958 ,  A61M1/36 ,  A61M25/00 ,  A61M25/01 ,  A61M25/06 ,  A61M29/02 ,  A61M31/00

CPC分类号： A61M25/0041 ,  A61F2/2433 ,  A61M1/3653 ,  A61M1/3659 ,  A61M25/007 ,  A61M25/0662 ,  A61M25/10 ,  A61M29/02 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61F2/2436 ,  A61M2025/0004 ,  A61M2025/0078 ,  A61M2025/028 ,  A61M2025/1047 ,  A61M2025/1052 ,  A61M2025/1077 ,  A61M2210/125 ,  A61M2210/127 ,  A61M25/0125

摘要： A venting catheter, system and method are provided for withdrawing blood and other fluids from a patient's heart to facilitate decompressing the heart during cardioplegic arrest and cardiopulmonary bypass, without the need for a thoracotomy and without puncturing the aorta, pulmonary artery, or heart itself. The venting catheter is configured to be introduced into a peripheral vein and intralumninally advanced through the right side of the heart and into the pulmonary artery. The venting catheter includes a lumen configured to withdraw blood at a rate of at least about 50 ml/min at a pressure of no less than about -350 mmHg. A flow-directing means is provided to facilitate guiding the catheter into the pulmonary artery by being carried by blood flow through the heart. The cardiac venting system may include, in addition to the cardiac venting catheter, a cardiopulmonary bypass system to maintain circulation of oxygenated blood, and means for arresting the patient's heart.

摘要翻译： 提供排气导管，系统和方法用于从心脏的心脏中抽出血液和其它流体，以便在心脏停搏和心肺分流期间减压心脏，而不需要开胸术，而不需要穿刺主动脉，肺动脉或心脏本身。 排气导管构造成引入外周静脉，并且通过心脏右侧进入肺内动脉。 排气导管包括被配置为在不低于约-350mmHg的压力下以至少约50ml / min的速率抽出血液的内腔。 提供流动引导装置以便于通过血流通过心脏而携带导管进入肺动脉。 除了心脏通气导管之外，心脏通气系统可以包括维持氧合血液循环的心肺旁路系统，以及用于阻止患者心脏的装置。

公开(公告)号：US5792094A

公开(公告)日：1998-08-11

申请号：US535676

申请日：1995-09-28

申请人： John H. Stevens ,  Wesley D. Sterman ,  Hanson S. Gifford, III ,  Philip C. Evard ,  Timothy R. Machold

发明人： John H. Stevens ,  Wesley D. Sterman ,  Hanson S. Gifford, III ,  Philip C. Evard ,  Timothy R. Machold

IPC分类号： A61B17/00 ,  A61B17/28 ,  A61B17/32 ,  A61F2/24 ,  A61F2/958 ,  A61M1/36 ,  A61M25/00 ,  A61M25/01 ,  A61M25/06 ,  A61M29/02 ,  A61M37/00

CPC分类号： A61F2/2427 ,  A61B17/29 ,  A61F2/2433 ,  A61M1/3653 ,  A61M1/3659 ,  A61M25/0041 ,  A61M25/0147 ,  A61M25/0152 ,  A61M25/0662 ,  A61M25/10 ,  A61B17/320016 ,  A61B2017/00243 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61F2/2436 ,  A61M2025/0031 ,  A61M2025/0078 ,  A61M2025/015 ,  A61M2025/0161 ,  A61M2025/028 ,  A61M2025/1047 ,  A61M2025/1052 ,  A61M2025/1077 ,  A61M2025/1095 ,  A61M2205/11 ,  A61M2205/366 ,  A61M2210/125 ,  A61M2210/127 ,  A61M25/0032 ,  A61M25/0125 ,  A61M25/1002

摘要： A system for accessing a patient's cardiac anatomy which includes an endovascular aortic partitioning device that separates the coronary arteries and the heart from the rest of the patient's arterial system. The endovascular device for partitioning a patient's ascending aorta comprises a flexible shaft having a distal end, a proximal end, and a fist inner lumen therebetween with an opening at the distal end. The shaft may have a preshaped distal portion with a curvature generally corresponding to the curvature of the patient's aortic arch. An expandable means, e.g. a balloon, is disposed near the distal end of the shaft proximal to the opening in the first inner lumen for occluding the ascending aorta so as to block substantially all blood flow therethrough for a plurality of cardiac cycles, while the patient is supported by cardiopulmonary bypass. The endovascular aortic partitioning device may be coupled to an arterial bypass cannula for delivering oxygenated blood to the patient's arterial system. The heart muscle or myocardium is paralyzed by the retrograde delivery of a cardioplegic fluid to the myocardium through patient's coronary sinus and coronary veins, or by antegrade delivery of cardioplegic fluid through a lumen in the endovascular aortic partitioning device to infuse cardioplegic fluid into the coronary arteries. The pulmonary trunk may be vented by withdrawing liquid from the trunk through an inner lumen of an elongated catheter. The cardiac accessing system is particularly suitable for removing the aortic valve and replacing the removed valve with a prosthetic valve.

摘要翻译： 一种用于访问患者心脏解剖结构的系统，其包括将冠状动脉和心脏与患者动脉系统的其余部分分离的血管内主动脉分配装置。 用于分隔患者升主动脉的血管内装置包括具有远端，近端和其中的第一内腔的柔性轴，在其前端具有开口。 轴可以具有预先形成的远端部分，其曲率通常对应于患者主动脉弓的曲率。 可膨胀装置，例如 靠近靠近第一内腔中的开口的轴的远端附近的气囊，用于闭塞升主动脉，以便阻止基本上所有的血液通过其进行多个心动周期，同时患者由体外循环 。 血管内主动脉分配装置可以联接到动脉旁路套管，用于将氧合血液输送到患者的动脉系统。 通过患者的冠状窦和冠状静脉逆行递送心脏停搏液到心肌，或者通过血管内主动脉分配装置的内腔顺序递送心脏停跳液，将心肌或心肌瘫痪，将心脏停搏液注入冠状动脉 。 可以通过从细长的导管的内腔中抽出液体来排出肺动脉干。 心脏存取系统特别适用于去除主动脉瓣并用假体瓣替换去除的瓣膜。

公开(公告)号：US5738652A

公开(公告)日：1998-04-14

申请号：US785079

申请日：1997-01-17

申请人： Stephen W. Boyd ,  John H. Stevens ,  Philip C. Evard ,  Craig L. Adams

发明人： Stephen W. Boyd ,  John H. Stevens ,  Philip C. Evard ,  Craig L. Adams

IPC分类号： A61B17/00 ,  A61B17/28 ,  A61B17/32 ,  A61F2/24 ,  A61F2/958 ,  A61M1/36 ,  A61M25/00 ,  A61M25/01 ,  A61M25/06 ,  A61M29/02 ,  A61M29/00

CPC分类号： A61B17/29 ,  A61F2/2427 ,  A61F2/2433 ,  A61M1/3653 ,  A61M1/3659 ,  A61M25/0041 ,  A61M25/0147 ,  A61M25/0152 ,  A61M25/0662 ,  A61M25/10 ,  A61B17/320016 ,  A61B2017/00243 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61F2/2412 ,  A61F2/2436 ,  A61M2025/0031 ,  A61M2025/004 ,  A61M2025/0078 ,  A61M2025/0161 ,  A61M2025/028 ,  A61M2025/1047 ,  A61M2025/1052 ,  A61M2025/1077 ,  A61M2025/1095 ,  A61M2205/11 ,  A61M2205/366 ,  A61M2210/125 ,  A61M2210/127 ,  A61M25/0032 ,  A61M25/0125 ,  A61M25/1002

摘要： A retrograde delivery catheter includes at its distal end a balloon configured to occlude the coronary sinus of a patient's heart, and has a length and flexibility which allow the distal end to be positioned in the coronary sinus with the proximal end extending transluminally to a peripheral vein such as an internal jugular vein and out of the body through a puncture therein. The delivery catheter has a delivery lumen extending between its proximal and distal ends which is configured to allow a cardioplegic fluid to be delivered at a flow rate of at least 200 ml/min with a pump pressure less than 300 mm Hg, thereby allowing cardioplegic arrest to be maintained using a blood cardioplegic fluid without causing excessive hemolysis. In a method of inducing cardioplegic arrest according to the invention, the patient is placed on cardiopulmonary bypass, the coronary arteries are isolated from remainder of the arterial system, and the delivery catheter is positioned transluminally in the coronary sinus from a peripheral vein. A cardioplegic fluid is then delivered to the coronary sinus through the delivery catheter at a flow rate of at least 200 ml/min and a pump pressure less than 300 mm Hg. The heart may be vented by withdrawing blood from the pulmonary artery through a catheter introduced through a peripheral vein, or withdrawing blood from the aortic root through an aortic catheter introduced through a peripheral artery.

公开(公告)号：US5536251A

公开(公告)日：1996-07-16

申请号：US415273

申请日：1995-04-03

申请人： Philip C. Evard ,  Timothy R. MacHold ,  Hanson S. Gifford, III ,  Alex T. Roth ,  Wesley D. Sterman ,  Lawrence C. Siegel

发明人： Philip C. Evard ,  Timothy R. MacHold ,  Hanson S. Gifford, III ,  Alex T. Roth ,  Wesley D. Sterman ,  Lawrence C. Siegel

IPC分类号： A61B1/00 ,  A61B17/00 ,  A61B17/02 ,  A61B17/04 ,  A61B17/06 ,  A61B17/064 ,  A61B17/068 ,  A61B17/12 ,  A61B17/122 ,  A61B17/128 ,  A61B17/28 ,  A61B17/30 ,  A61B17/34 ,  A61B18/14 ,  A61B19/00 ,  A61F2/24 ,  A61F2/958 ,  A61M1/00 ,  A61M25/00 ,  A61M25/01 ,  A61M11/00

CPC分类号： A61B17/0218 ,  A61B17/00234 ,  A61B17/0469 ,  A61B17/06061 ,  A61B17/12013 ,  A61B17/122 ,  A61B17/1227 ,  A61B17/1285 ,  A61B18/1442 ,  A61B18/1492 ,  A61B90/50 ,  A61F2/2427 ,  A61M25/01 ,  A61M39/0247 ,  A61B17/0057 ,  A61B17/0467 ,  A61B17/064 ,  A61B17/068 ,  A61B17/29 ,  A61B17/2909 ,  A61B17/295 ,  A61B17/30 ,  A61B17/34 ,  A61B17/3403 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00353 ,  A61B2017/00544 ,  A61B2017/00637 ,  A61B2017/00663 ,  A61B2017/0243 ,  A61B2017/047 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/2905 ,  A61B2017/2933 ,  A61B2017/2943 ,  A61B2017/2945 ,  A61B2017/2946 ,  A61B2017/306 ,  A61B2017/3405 ,  A61B2017/3427 ,  A61B2017/3445 ,  A61B2017/3492 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00291 ,  A61B2018/00363 ,  A61B2018/00392 ,  A61B2018/00577 ,  A61B2018/1432 ,  A61B2090/064 ,  A61M2025/0003 ,  A61M2025/0089 ,  A61M2025/028 ,  A61M2039/0279 ,  A61M2202/047 ,  A61M2205/3344 ,  A61M2205/3355 ,  A61M2205/366 ,  A61M2210/127 ,  A61M25/1011 ,  Y10S128/26

摘要： The invention provides devices and methods for thoracoscopically arresting the heart and establishing cardiopulmonary bypass, thus facilitating a variety of less-invasive surgical procedures on and within the heart and great vessels of the thorax. In one embodiment, the invention provides a thoracoscopic system for arresting a patient's heart including a clamp configured for introduction into the patient's thoracic cavity through a percutaneous intercostal penetration in the patient's chest. The clamp is positionable about the patient's ascending aorta between the coronary arteries and the brachiocephalic artery. The clamp is coupled to the distal end of an elongated handle means for manipulating the clamp from a location outside of the patient's thoracic cavity. A means for actuating the clamp is coupled to the proximal end of the handle means. When actuated, the clamp blocks blood flow through the ascending aorta. A delivery cannula may be used to deliver cardioplegic fluid into the ascending aorta upstream from the clamp to arrest cardiac function.