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    Microwave oven with uniform electric field distribution
    2.
    发明授权
    Microwave oven with uniform electric field distribution 失效
    具有均匀电场分布的微波炉

    公开(公告)号：US4019010A

    公开(公告)日：1977-04-19

    申请号：US562412

    申请日：1975-03-27

    申请人： Junzo Tanaka ,  Haruo Matsushima ,  Yukio Abe

    发明人： Junzo Tanaka ,  Haruo Matsushima ,  Yukio Abe

    IPC分类号： F24C7/02 ,  H05B6/74 ,  H05B6/80 ,  H05B9/06

    CPC分类号： H05B6/725 ,  H05B6/6426 ,  H05B6/705 ,  H05B6/74 ,  Y02B40/146

    摘要： A microwave oven having an improved electric field distribution to allow uniform heating of an article to be heated is disclosed. High frequency exciting means is positioned at the center, both depthwise and lengthwise, of a heating chamber of substantially parallelepiped structure, and the shapes and construction of the reflecting plate, stirrer vane, mount for partition and heating cavity are improved to allow uniform electric field distribution and improvement in cooking performance.

    摘要翻译： 公开了一种具有改善的电场分布以允许待加热物品均匀加热的微波炉。 高频激励装置位于基本上平行六面体结构的加热室的中心（纵向和纵向）的中心，并且反射板，搅拌器叶片，用于分隔和加热腔的安装座的形状和结构得到改善以允许均匀的电场 分布和改善烹饪表现。

    DRUG-CONTAINING SUSTAINED RELEASE MICROPARTICLE, PROCESS FOR PRODUCING THE SAME AND PREPARATION CONTAINING THE MICROPARTICLE
    5.
    发明申请
    DRUG-CONTAINING SUSTAINED RELEASE MICROPARTICLE, PROCESS FOR PRODUCING THE SAME AND PREPARATION CONTAINING THE MICROPARTICLE 失效
    包含持续释放微生物的药物，其生产方法和含有微生物的制剂

    公开(公告)号：US20100322902A1

    公开(公告)日：2010-12-23

    申请号：US12837810

    申请日：2010-09-02

    申请人： Yutaka Mizushima ,  Yasuaki Ogawa ,  Junzo Tanaka ,  Toshiyuki Ikoma

    发明人： Yutaka Mizushima ,  Yasuaki Ogawa ,  Junzo Tanaka ,  Toshiyuki Ikoma

    IPC分类号： A61K38/21 ,  A61K47/02 ,  A61K31/573

    CPC分类号： A61K31/00 ,  A61K9/1611 ,  A61K33/30 ,  A61K33/42 ,  A61K45/06 ,  A61K2300/00

    摘要： Sustained release microparticles suitable for various types of drugs, or drug-containing sustained release microparticles capable of sustained release of drugs over a period of three days or more and capable of inhibiting initial burst release; a process for producing the same; and preparations containing the microparticles are disclosed. The drug-containing sustained release microparticles comprise a drug other than human growth hormone and a porous apatite derivative, and optionally include a water-soluble bivalent metal compound. The drug-containing sustained release microparticles can be produced by dispersing under agitation microparticles of a porous apatite derivative in an aqueous solution containing a drug so that the aqueous solution infiltrates into the porous apatite derivative; optionally adding an aqueous solution containing a water-soluble bivalent metal compound that may infiltrate into the porous apatite derivative; further adding additives such as a stabilizer to the mixture; and effecting lyophilization or vacuum drying.

    摘要翻译： 适用于各种类型药物的持续释放微粒，或能够在三天或更长时间内持续释放药物并且能够抑制初始爆发释放的药物持续释放微粒; 其制造方法; 并且公开了含有微粒的制剂。 含药物的缓释微粒包含除人生长激素以外的药物和多孔磷灰石衍生物，任选地包含水溶性二价金属化合物。 含药缓释微粒可以通过将多孔磷灰石衍生物的微粒分散在含有药物的水溶液中分散而制成，使得水溶液渗透到多孔磷灰石衍生物中; 任选地加入含有可渗透到多孔磷灰石衍生物中的水溶性二价金属化合物的水溶液; 进一步向混合物中加入稳定剂等添加剂; 并进行冻干或真空干燥。

    Biological low-molecular-weight derivatives
    7.
    发明授权
    Biological low-molecular-weight derivatives 失效
    生物低分子量衍生物

    公开(公告)号：US07741454B2

    公开(公告)日：2010-06-22

    申请号：US10527694

    申请日：2003-09-11

    申请人： Tetsushi Taguchi ,  Hisatoshi Kobayashi ,  Junzo Tanaka ,  Hirofumi Saito

    发明人： Tetsushi Taguchi ,  Hisatoshi Kobayashi ,  Junzo Tanaka ,  Hirofumi Saito

    IPC分类号： C07K1/00 ,  C07K14/00 ,  C07K17/00 ,  C07K16/00 ,  C08H1/00 ,  A61F2/00 ,  A61K31/74 ,  A61F13/15 ,  A61F13/20

    CPC分类号： C07D207/02 ,  C07D207/46

    摘要： The crosslinking agents and condensing agents that have been employed in biological adhesives and in treating medical devices such as cardiac valves are non-natural compounds synthesized artificially. Thus, they are not metabolized in vivo and exhibit toxicity to living bodies. These compounds are thus used only in a restricted amount and for limited purposes in the clinical sites. The present invention provides a biological low-molecular-weight derivative obtained by modifying carboxyl groups of a biological low-molecular-weight compound with N-hydroxysuccinimide, N-hydroxysulfosuccinimide, or a derivative thereof and a crosslinked high-molecular-weight product obtained by crosslinking various high-molecular-weight compounds with this derivative.

    摘要翻译： 已经用于生物粘合剂和治疗医疗装置如心脏瓣膜的交联剂和缩合剂是人工合成的非天然化合物。 因此，它们不会在体内代谢并对活体表现出毒性。 因此，这些化合物仅在临床部位中仅限于有限的目的和用途。 本发明提供一种通过用N-羟基琥珀酰亚胺，N-羟基磺基琥珀酰亚胺或其衍生物修饰生物低分子量化合物的羧基得到的生物学低分子量衍生物和通过以下方法得到的交联的高分子量产物： 用该衍生物交联各种高分子量化合物。