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    SEMICONDUCTOR MICRO-ANALYSIS CHIP AND METHOD OF MANUFACTURING THE SAME
    4.
    发明申请
    SEMICONDUCTOR MICRO-ANALYSIS CHIP AND METHOD OF MANUFACTURING THE SAME 审中-公开
    半导体微分析芯片及其制造方法

    公开(公告)号：US20150041316A1

    公开(公告)日：2015-02-12

    申请号：US14198425

    申请日：2014-03-05

    Applicant: KABUSHIKI KAISHA TOSHIBA

    Inventor： Hiroko MIKI ,  Hideto FURUYAMA ,  Kentaro KOBAYASHI ,  Akihiro KOJIMA

    IPC: G01N27/28 ,  H01L21/306 ,  G01N33/487

    CPC classification number: B01L3/502753 ,  B01L2200/0647 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2400/086 ,  G01N15/1031 ,  G01N15/1484 ,  G01N2015/0053 ,  G01N2015/1006 ,  G01N2015/1486

    Abstract: One of embodiments is a semiconductor micro-analysis chip for detecting particles in a sample liquid. The chip comprises a semiconductor substrate, a first flow channel provided on the semiconductor substrate to allow the sample liquid to flow therein, a second flow channel provided at a different position from the first flow channel of the semiconductor substrate to allow the sample liquid or an electrolyte solution to flow therein, a contact portion where a portion of the first flow channel and a portion of the second flow channel abut each other or intersect one another with a partition being arranged between the flow channels, and a fine hole provided on the partition of the contact portion to allow the particles to pass therethrough.

    Abstract translation: 一个实施例是用于检测样品液体中的颗粒的半导体微分析芯片。 芯片包括半导体衬底，设置在半导体衬底上以允许样品液体流过的第一流动通道，设置在与半导体衬底的第一流动通道不同的位置处的第二流动通道，以允许样品液体或 在其中流动的电解质溶液，其中第一流动通道的一部分和第二流动通道的一部分彼此邻接或相互交叉的接触部分设置在流动通道之间的分隔件和设置在分隔件上的细孔 的接触部分以允许颗粒通过。

    FET SENSOR USING ANTIOXIDANT
    6.
    发明公开
    FET SENSOR USING ANTIOXIDANT 审中-公开

    公开(公告)号：US20230304964A1

    公开(公告)日：2023-09-28

    申请号：US17930415

    申请日：2022-09-07

    Applicant: KABUSHIKI KAISHA TOSHIBA

    Inventor： Yoshiaki SUGIZAKI ,  Hiroko MIKI

    IPC: G01N27/414

    CPC classification number: G01N27/4146 ,  G01N27/4145 ,  H01L29/1606

    Abstract: According to one embodiment, an FET sensor includes a sensitive film including a carbon allotrope, a liquid film disposed so as to cover the sensitive film, a source electrode and a drain electrode electrically connected to the sensitive film, and a gate electrode configured to apply an electric field to the sensitive film, wherein the liquid film comprises an antioxidant.

    PARTICLE INSPECTION UNIT AND PARTICLE INSPECTION SYSTEM
    7.
    发明申请
    PARTICLE INSPECTION UNIT AND PARTICLE INSPECTION SYSTEM 审中-公开
    颗粒检查单元和颗粒检查系统

    公开(公告)号：US20160320286A1

    公开(公告)日：2016-11-03

    申请号：US15205691

    申请日：2016-07-08

    Applicant: KABUSHIKI KAISHA TOSHIBA

    Inventor： Hiroko MIKI ,  Michihiko NISHIGAKI ,  Kentaro KOBAYASHI ,  Naofumi NAKAMURA

    IPC: G01N15/12 ,  G01N27/447 ,  G01N21/78

    CPC classification number: G01N15/12 ,  B01L3/502761 ,  G01N15/1031 ,  G01N21/78 ,  G01N27/44791 ,  G01N2015/1006 ,  G01N2015/1263

    Abstract: According to one embodiment, a particle inspection system includes an inspection module and a determination module. The inspection module includes a particle inspection chip includes electrodes for detecting existence of particles in a sample liquid by a change in an electrical signal, and a memory element which is provided separately from the electrodes and configured to store whether the inspection chip is a used chip or not. The determination module includes a determination circuit configured to determine the existence of the particles based on a detection signal of the inspection chip, and a control circuit configured to control an operation of the determination circuit from information in the memory element.

    Abstract translation: 根据一个实施例，颗粒检查系统包括检查模块和确定模块。 检查模块包括：粒子检查芯片，包括用于通过电信号的变化来检测样品液体中的颗粒的存在的电极;以及与电极分开设置的存储元件，其被配置为存储检查芯片是否是使用的芯片 或不。 确定模块包括确定电路，其被配置为基于检查芯片的检测信号确定颗粒的存在;以及控制电路，被配置为根据存储元件中的信息控制确定电路的操作。

    ANALYSIS PACKAGE
    8.
    发明申请
    ANALYSIS PACKAGE 有权
    分析包

    公开(公告)号：US20160231262A1

    公开(公告)日：2016-08-11

    申请号：US14848307

    申请日：2015-09-08

    Applicant: KABUSHIKI KAISHA TOSHIBA

    Inventor： Hiroshi HAMASAKI ,  Michihiko NISHIGAKI ,  Yutaka ONOZUKA ,  Kentaro KOBAYASHI ,  Hiroko MIKI ,  Naofumi NAKAMURA

    IPC: G01N27/00 ,  B01L3/00

    CPC classification number: B01L3/502715 ,  B01L3/5027 ,  B01L2200/0647 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2400/0421 ,  B01L2400/086 ,  G01N15/12 ,  G01N27/3273 ,  G01N33/48721

    Abstract: According to one embodiment, an analysis package, including a board, an analysis chip provided on the board, the chip including a detector for detecting a particle, a flow channel of a sample liquid, and a liquid receiver of the sample liquid, a first mold layer provided on the analysis chip, the first mold layer including an opening above the liquid receiver, and a second mold layer provided on the board and the first mold layer, the second mold layer including an opening above the opening of the first mold layer, wherein the respective openings of the first and second mold layers are connected above the liquid receiver to allow the sample liquid to be introduced into the liquid receiver from outside.

    Abstract translation: 根据一个实施例，包括板的分析包，设置在板上的分析芯片，包括用于检测颗粒的检测器，样品液体的流动通道和样品液体的液体接收器的芯片，第一 设置在分析芯片上的模具层，第一模具层包括在液体接收器上方的开口，以及设置在板和第一模具层上的第二模具层，第二模具层包括在第一模具层的开口上方的开口 其中第一和第二模具层的相应开口连接在液体接收器上方，以允许样品液体从外部引入到液体接收器中。

    NUCLEIC ACID PROBE, CHEMICAL SENSOR, AND DETECTION METHOD
    9.
    发明申请
    NUCLEIC ACID PROBE, CHEMICAL SENSOR, AND DETECTION METHOD 有权

    公开(公告)号：US20250093291A1

    公开(公告)日：2025-03-20

    申请号：US18760449

    申请日：2024-07-01

    Applicant: KABUSHIKI KAISHA TOSHIBA

    Inventor： Yoshiaki SUGIZAKI ,  Hiroko MIKI

    IPC: G01N27/327 ,  C12N15/115 ,  G01N33/94

    Abstract: A nucleic acid probe includes first and second nucleic acids. The first nucleic acid includes a binding site. The first nucleic acid includes first to seventh base sequences. The fourth base sequence is complimentary with the third base sequence. The fifth base sequence is complimentary with the second base sequence. The seventh base sequence is complimentary with the sixth base sequence. The binding site is positioned at least between the fourth base sequence and the seventh base sequence. The second nucleic acid includes an eighth base sequence. The eighth base sequence is complimentary with at least a portion of the first base sequence and at least a portion of the second base sequence. A number of bases of the eighth base sequence is more than a number of bases of the second base sequence.

    DETECTION DEVICE, DETECTION METHOD, AND ELECTRODE WITH PROBE
    10.
    发明申请
    DETECTION DEVICE, DETECTION METHOD, AND ELECTRODE WITH PROBE 审中-公开

    公开(公告)号：US20190064157A1

    公开(公告)日：2019-02-28

    申请号：US15908700

    申请日：2018-02-28

    Applicant: KABUSHIKI KAISHA TOSHIBA

    Inventor： Takuya MIYAGAWA ,  Sadato HONGO ,  Hiroko MIKI ,  Hiroshi HAMASAKI ,  Kentaro KOBAYASHI ,  Ping WANG ,  Naofumi NAKAMURA

    IPC: G01N33/543

    Abstract: According to one embodiment, a detection device is disclosed. The detection device includes a first region, a first electrode on the first region, a second region, a second electrode on the second region, a partition partitioning the first region and the second region and including a through hole, thereby communicating the first region with the second region. The device further includes a probe which binds specifically to the detection target, and is detachably connected to the first electrode, a detacher to detach the probe from the first electrode, a determination unit to determine whether the first liquid contains a detection target based on a change of electrical condition between the first electrode and the second electrode in a state where the first region and the second region are supplied with the first liquid and the second liquid, respectively.

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