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公开(公告)号：US06885448B2
公开(公告)日：2005-04-26
申请号：US10276994
申请日：2002-03-26
CPC分类号： G01N15/0211 , G01J2001/442 , G01N2013/003
摘要： A photon correlator comprises a plurality of sampling gates 11a-11e which are open during different periods of time; a plurality of memories 12a-12e each provided corresponding to each of the plurality of sampling gates 11a-11e for storing data corresponding to the number of photons; and a data processing control section for reading out the data stored in the memories 12a-12e, and performing a correlation calculation by means of software. The mechanism of the hardware comprising the sampling gates 11a-11e and memories 12a-12e enables high-speed writing of data in the memories and real-time read out of the data. In addition, the software performs correlation calculations in parallel with the above processing. Accordingly, the particle sizes and diffusion coefficient of particles in a fluid can be obtained at high speed under various conditions.
摘要翻译： 光子相关器包括在不同时间段内打开的多个采样门11a至11e; 每个对应于多个采样门11 a-11e中的每一个提供的多个存储器12a-12e，用于存储对应于光子数量的数据; 以及数据处理控制部分，用于读出存储在存储器12a-12e中的数据，并通过软件进行相关计算。 包括采样门11 a-11 e和存储器12 a-12 e的硬件的机制使得能够高速地将数据写入存储器并实时读出数据。 此外，软件与上述处理并行执行相关计算。 因此，可以在各种条件下高速地获得流体中的颗粒的粒径和扩散系数。
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2.发明授权
公开(公告)号：US5964712A
公开(公告)日：1999-10-12
申请号：US849351
申请日：1997-06-06
申请人： Yasuhiro Kubo , Katsuhiro Morisawa , Yasushi Zasu , Eiji Ikegami , Kazunori Tsutsui , Tamotsu Hamao , Masaaki Mori , Takashi Maruyama
发明人： Yasuhiro Kubo , Katsuhiro Morisawa , Yasushi Zasu , Eiji Ikegami , Kazunori Tsutsui , Tamotsu Hamao , Masaaki Mori , Takashi Maruyama
IPC分类号： A61B5/00 , A61B5/08 , A61B5/083 , A61B5/097 , A61B10/00 , G01N1/22 , G01N21/03 , G01N21/11 , G01N21/25 , G01N21/27 , G01N21/31 , G01N21/35 , G01N21/59 , G01N33/00 , G01N33/497 , G01N35/08 , B01L3/00
CPC分类号： G01N21/3504 , A61B10/00 , A61B5/097 , G01N21/0332 , G01N21/11 , G01N21/274 , G01N21/314 , A61B2010/0087 , A61B5/0059 , A61B5/0836 , G01N33/0006 , G01N33/497
摘要： A correction curve (FIG. 19) is prepared by plotting .sup.12 CO.sub.2 concentrations and .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratios which are determined on the basis of a calibration curve and .sup.13 CO.sub.2 and .sup.12 CO.sub.2 absorbances of gaseous samples having the same .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratio but known different .sup.12 CO.sub.2 concentrations. A gaseous test sample containing .sup.13 CO.sub.2 and .sup.12 CO.sub.2 as component gases is introduced into a cell, and spectrometrically measured. A .sup.12 CO.sub.2 concentration of the gaseous test sample is determined by way of the spectrometric measurement. A concentration ratio correction value is obtained on the basis of the correction curve and the .sup.12 CO.sub.2 concentration of the gaseous test sample thus determined. A measured .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratio is divided by the concentration ratio correction value thus obtained for correction of the .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratio. Thus, the measurement accuracy of the concentration ratios of the component gases can be improved. A breath sampling bag and gas measuring system is also disclosed where each is configured such that breath inlets of the gas measuring apparatus are prevented from being respectively connected to the wrong breath introduction pipes of the breath sampling bag.
摘要翻译： PCT No.PCT / JP96 / 02876 Sec。 371日期：1997年6月6日 102（e）日期1996年6月6日PCT提交1996年10月2日PCT公布。 公开号WO97 / 14029 日期1997年04月17日通过绘制12CO2浓度和13CO2 / 12CO2浓度比，制备校正曲线（图19），其基于校准曲线确定，并且具有13CO 2 / 12CO 2浓度的气态样品的13CO 2和12 CO 2吸光度 比例但已知不同的12CO2浓度。 将含有作为组分气体的13CO 2和12 CO 2的气态测试样品引入到电池中，并进行光谱测量。 通过光谱测量法测定气态测试样品的12CO2浓度。 基于如此确定的气体试样的校正曲线和12CO 2浓度获得浓度比校正值。 测量的13CO 2 / 12CO 2浓度比除以由此获得的用于校正13CO 2 / 12CO 2浓度比的浓度比校正值。 因此，能够提高成分气体的浓度比的测定精度。 还公开了一种呼吸取样袋和气体测量系统，其中每个呼气采样袋和气体测量系统被配置为使得气体测量装置的呼吸入口被防止分别连接到呼吸取样袋的错误的呼吸导管。
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3.发明授权公开(公告)号：US06274870B1
公开(公告)日：2001-08-14
申请号：US09303427
申请日：1999-05-03
申请人： Yasuhiro Kubo , Katsuhiro Morisawa , Yasushi Zasu , Eiji Ikegami , Kazunori Tsutsui , Tamotsu Hamao , Masaaki Mori , Takashi Maruyama
发明人： Yasuhiro Kubo , Katsuhiro Morisawa , Yasushi Zasu , Eiji Ikegami , Kazunori Tsutsui , Tamotsu Hamao , Masaaki Mori , Takashi Maruyama
IPC分类号： G01N2135
CPC分类号： G01N21/3504 , A61B5/0059 , A61B5/0836 , A61B5/097 , A61B10/00 , A61B2010/0087 , G01N21/0332 , G01N21/11 , G01N21/274 , G01N21/314 , G01N33/0006 , G01N33/497
摘要： A correction curve (FIG. 19) is prepared by plotting 12CO2 concentrations and 13CO2/12CO2 concentration ratios which are determined on the basis of a calibration curve and 13CO2 and 12CO2 absorbances of gaseous samples having the same 13CO2/12CO2 concentration ratio but known different 12CO2 concentrations. A gaseous test sample containing 13CO2 and 12CO2 as component gases is introduced into a cell, and spectrometrically measured. A 12CO2 concentration of the gaseous test sample is determined by way of the spectrometric measurement. A concentration ratio correction value is obtained on the basis of the correction curve and the 12CO2 concentration of the gaseous test sample thus determined. A measured 13CO2/12CO2 concentration ratio is divided by the concentration ratio correction value thus obtained for correction of the 13CO2/12CO2 concentration ratio. Thus, the measurement accuracy of the concentration ratios of the component gases can be improved.
摘要翻译： 通过绘制12CO2浓度和13CO2 / 12CO2浓度比，通过绘制12CO2浓度和13CO2 / 12CO2浓度比来制备校正曲线（13CO2 / 12CO2浓度比），这些浓度比是根据13CO2 / 12CO2浓度比相同但已知不同12CO2的气态样品的校正曲线和13CO2和12CO2吸光度确定的 浓度 将含有作为组分气体的13CO 2和12 CO 2的气态测试样品引入到电池中，并进行光谱测量。 通过光谱测量法测定气态测试样品的12CO2浓度。 基于如此确定的气体试样的校正曲线和12CO 2浓度获得浓度比校正值。 测量的13CO 2 / 12CO 2浓度比除以由此获得的用于校正13CO 2 / 12CO 2浓度比的浓度比校正值。 因此，能够提高成分气体的浓度比的测定精度。
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公开(公告)号：US07449097B2
公开(公告)日：2008-11-11
申请号：US10784278
申请日：2004-02-24
IPC分类号： G01N27/453
CPC分类号： G01N27/447 , G01N15/00 , G01N27/44721 , G01N2015/0003 , G01N2015/1075 , G01S17/58
摘要： The present invention provides an electrophoretic mobility measuring apparatus capable of conducting measurement with high sensitivity with optical attenuation reduced by incidence of light through the electrode face. This apparatus comprises a transparent electrode 63 forming a part of a cell wall of a cell 6 capable of confining a sample, and the other electrode 62 opposite to the transparent electrode 63. A voltage is applied across these electrodes 62, 63, and light is incident upon the inside of the cell 6 through the transparent electrode 63. The scattering light which scatters from a sample S at a predetermined angle θ with respect to the incident angle, is received through the transparent electrode 63. The Doppler displacement is then measured based on the difference in frequency between the incident light and the outgoing light. The direction of the scattering vector which is the vector difference between incident and outgoing vectors, is substantially identical with that of the normal line h of the transparent electrode face.
摘要翻译： 本发明提供一种能够以高灵敏度进行测量的电泳迁移率测量装置，通过电极面的光入射减少光衰减。 该装置包括形成能够限制样品的单元6的单元壁的一部分的透明电极63和与透明电极63相对的另一个电极62。 在这些电极62,63之间施加电压，并且光通过透明电极63入射到电池6的内部。 通过透明电极63接收从样品S以相对于入射角以预定角度θ散射的散射光。 然后基于入射光和出射光之间的频率差来测量多普勒位移。 作为入射矢量与向外矢量之间的矢量差的散射矢量的方向与透明电极面的法线h基本相同。
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5.发明申请Electrophoretic Mobility Measurement Cell And Measurement Apparatus And Method Using The Same 有权电泳移动性测量单元及测量装置及其使用方法公开(公告)号：US20140027286A1
公开(公告)日：2014-01-30
申请号：US14045342
申请日：2013-10-03
IPC分类号： G01N27/447
CPC分类号： G01N27/44756 , C07K1/26 , G01N27/44721
摘要： An electrophoretic mobility measurement cell includes a container having a rectangular parallelepiped internal space for introducing a sample solution, two electrodes for applying an electric field to the internal space, tubular sample injection and extraction portions in communication with the internal space, first and second caps for covering the sample injection and extraction portions and sealing the internal space, the first cap has a first side surface contacting an inner side surface of the tubular sample injection portion, the inner side surface formed so that the cross-sectional area of the tube increases with distance from the internal space, and the area of the cross section of the first side surface decreases in the direction of insertion of the first cap. The cell and electrode portions are formed integrally, the electrode portions are made disposable together with the cell, and bubbles are unlikely to remain during injection of the sample solution.
摘要翻译： 电泳迁移率测量单元包括具有用于引入样品溶液的长方体内部空间的容器，用于向内部空间施加电场的两个电极，与内部空间连通的管状样品注入和提取部分，第一和第二盖子 覆盖样品注射和提取部分并密封内部空间，第一盖具有接触管状样品注射部分的内侧表面的第一侧面，形成为使得管的横截面积随着 距离内部空间的距离，并且第一侧表面的横截面的面积在第一盖的插入方向上减小。 电池和电极部分一体地形成，电极部分与电池一起被一次性地放置在一起，并且在注射样品溶液期间气泡不可能保留。
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公开(公告)号：US5015094A
公开(公告)日：1991-05-14
申请号：US413647
申请日：1989-09-28
申请人： Koichi Oka , Akira Kawaguchi , Kunio Kumagai , Katsuhiro Morisawa
发明人： Koichi Oka , Akira Kawaguchi , Kunio Kumagai , Katsuhiro Morisawa
CPC分类号： G06T7/60 , G01N15/0205 , G01N2015/0222
摘要： There is disclosed a system in which, according to the time domain method, a laser light is irradiated to an object to be measured, photon pulses based on the scattering light from the object to be measured are received, time series data are generated based on the light receiving signal, and based on the time series data thus generated, the particle size distribution of particles in the object to be measured is measured. Thus, the present invention achieves a considerable reduction in time required for finally obtaining the particle size based on the measured data, as compared with a conventional system using a calculator program.
摘要翻译： 公开了一种系统，其中根据时域方法将激光照射到待测物体上，接收基于来自待测物体的散射光的光子脉冲，基于 光接收信号，并且基于如此生成的时间序列数据，测量被测量物体中的粒子的粒度分布。 因此，与使用计算器程序的常规系统相比，本发明实现了基于测量数据最终获得粒度所需的时间的显着减少。
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7.发明授权公开(公告)号：US08999131B2
公开(公告)日：2015-04-07
申请号：US14045342
申请日：2013-10-03
IPC分类号： G01N27/447 , C07K1/26
CPC分类号： G01N27/44756 , C07K1/26 , G01N27/44721
摘要： An electrophoretic mobility measurement cell includes a container having a rectangular parallelepiped internal space for introducing a sample solution, two electrodes for applying an electric field to the internal space, tubular sample injection and extraction portions in communication with the internal space, first and second caps for covering the sample injection and extraction portions and sealing the internal space, the first cap has a first side surface contacting an inner side surface of the tubular sample injection portion, the inner side surface formed so that the cross-sectional area of the tube increases with distance from the internal space, and the area of the cross section of the first side surface decreases in the direction of insertion of the first cap. The cell and electrode portions are formed integrally, the electrode portions are made disposable together with the cell, and bubbles are unlikely to remain during injection of the sample solution.
摘要翻译： 电泳迁移率测量单元包括具有用于引入样品溶液的长方体内部空间的容器，用于向内部空间施加电场的两个电极，与内部空间连通的管状样品注入和提取部分，第一和第二盖子 覆盖样品注射和提取部分并密封内部空间，第一盖具有接触管状样品注射部分的内侧表面的第一侧面，形成为使得管的横截面积随着 距离内部空间的距离，并且第一侧表面的横截面的面积在第一盖的插入方向上减小。 电池和电极部分一体地形成，电极部分与电池一起被一次性地放置在一起，并且在注射样品溶液期间气泡不可能保留。
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