摘要:
A system for electronically storing and retrieving information. Information is scanned into the system and a user manually designates that the information is to be sorted using boxes which are like folders, sorted by date, or sorted by a card such as by cards which are arranged alphabetically. When the user manually indicates that the information is to be sorted by box, there is also an automatic sort by date and by card. In this case the card which is used is a temporary sort card which is automatically designated. When the user manually indicates that the sort is other than by box, the information is automatically sorted into a temporary box. After the information is stored and sorted, the information can be retrieved and printed, as desired. The system utilizes a scanner, processor, storage device and printer.
摘要:
An attaching unit attaches an additional-information packet to a collection of main information, wherein the additional-information packet comprises sensory information corresponding to sensory impressions of a human being that has processed the collection of main information, the sensory impressions being with respect to circumstances under which the collection of main information has been processed.
摘要:
An attaching unit attaches an additional-information packet to a collection of main information, wherein the additional-information packet comprises sensory information corresponding to sensory impressions of a human being that has processed the collection of main information, the sensory impressions being with respect to circumstances under which the collection of main information has been processed.
摘要:
A dipeptidyl peptidase IV inhibitor which is satisfactory in respect of activity, stability and safety and has an excellent action as a pharmaceutical agent. A compound represented by the following general formula or a pharmaceutically acceptable salt thereof: wherein R1 and R2 each represents hydrogen, an optionally substituted C1-6 alkyl group, or —COOR5 whereupon R5 represents hydrogen or an optionally substituted C1-6 alkyl group, or R1, R2, and a carbon atom together represent a 3- to 6-membered cycloalkyl group, R3 represents hydrogen or an optionally substituted C6-10 aryl group, R4 represents a hydrogen or a cyano group, D represents —CONR6—, —CO— or —NR6CO—, R6 represents hydrogen or an optionally substituted C1-6 alkyl group, E represents —(CH2)m— whereupon m is 1 to 3, —CH2OCH2—, or —SCH2—, n is 0 to 3, and A represents an optionally substituted bicyclic heterocyclic group or bicyclic hydrocarbon group.
摘要:
The present invention aims at providing a peptide fragment capable of improving biostability of a bioactive substance while maintaining the activity of the bioactive substance, and a bioactive substance to which the peptide fragment is added. The present invention relates to a partial peptide of a GA module having 5 to 25 amino acids, including a partial sequence of a GA module (SEQ ID NO: 1) and the amino acid sequence Ile-Asp-Glu-Ile-Leu (SEQ ID NO: 2), and a bioactive complex in which the partial peptide of the GA module is bound to a bioactive substance. The bioactive substance includes GLP-1, GLP-2, GIP, VIP, somatostatin, amylin, ghrelin, derivatives thereof, and the like.
摘要翻译:本发明的目的在于提供能够提高生物活性物质生物活性的肽片段,同时保持生物活性物质的活性,以及加入肽片段的生物活性物质。 本发明涉及具有5至25个氨基酸的GA模块的部分肽,包括GA模块(SEQ ID NO:1)和氨基酸序列Ile-Asp-Glu-Ile-Leu(SEQ ID NO:1)的部分序列 ID NO:2),以及GA模块的部分肽与生物活性物质结合的生物活性复合物。 生物活性物质包括GLP-1,GLP-2,GIP,VIP,生长抑素,胰岛淀粉样多肽,生长素释放肽及其衍生物等。
摘要:
A dipeptidyl peptidase IV inhibitor which is satisfactory in respect of activity, stability and safety and has an excellent action as a pharmaceutical agent. A compound represented by the following general formula or a pharmaceutically acceptable salt thereof: wherein R1 and R2 each represents hydrogen, an optionally substituted C1-6 alkyl group, or —COOR5 whereupon R5 represents hydrogen or an optionally substituted C1-6 alkyl group, or R1, R2, and a carbon atom together represent a 3- to 6-membered cycloalkyl group, R3 represents hydrogen or an optionally substituted C6-10 aryl group, R4represents a hydrogen or a cyano group, D represents —CONR6-, —CO— or —NR6CO—, R6 represents hydrogen or an optionally substituted C1-6 alkyl group, E represents —(CH2)m— whereupon m is 1 to 3, —CH2OCH2—, or —SCH2—, n is 0 to 3, and A represents an optionally substituted bicyclic heterocyclic group or bicyclic hydrocarbon group.
摘要:
Compounds of formula A and formula B: and their pharmaceutically acceptable salts, compositions comprising them, methods for their use, and their use in the preparation of medicaments. The compounds are antagonists of MCP-1 function, and are useful in the prevention and treatment of chronic or acute inflammatory or autoimmune diseases, such as multiple sclerosis, and in the prevention and treatment of allergic hypersensitivity disorders.