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公开(公告)号:US10274460B2
公开(公告)日:2019-04-30
申请号:US15124168
申请日:2015-03-06
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Ian Walton , Achim Karger , Alexander Khorlin , Michael Simon , Adam Sannicandro , Alexander Dukhovny , Robert Cobene , Dan Kline , John Dixon
IPC: G01N27/447
Abstract: The present disclosure relates, in some embodiments, to an apparatus for conducting a capillary electrophoresis assay. The apparatus can comprise a capillary array comprising an anode end and a cathode end, the capillary array provided in a housing further comprising a reservoir configured to house a separation medium and an anode buffer. The system can also comprise an injection mechanism configured to deliver sample to the cathode end of the capillary array, and a temperature control zone, wherein the temperature control zone is configured to control the temperature of the interior of the housing.
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2.
公开(公告)号:US20150044758A1
公开(公告)日:2015-02-12
申请号:US14462640
申请日:2014-08-19
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Joseph Amshey , Daniel Bezdek , Espir Kahatt , Alexander Khorlin , Lance Parsons , Todd Peterson , Timothy Powers , Michael Thacker , Timothy Updyke , Kornelija Zgonc
IPC: B01L3/00
CPC classification number: B01L3/502715 , B01L3/50273 , B01L7/00 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0689 , B01L2200/10 , B01L2200/16 , B01L2300/0636 , B01L2300/0681 , B01L2300/0867 , B01L2300/088 , B01L2300/123 , B01L2400/0481 , B01L2400/0487 , B01L2400/0605 , B01L2400/0655 , G01N2035/00306 , G01N2035/1037 , Y10T436/2575
Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing. Other embodiments include automated systems, automated devices, automated cartridges and automated methods for separation, preparation and purification of nucleic acids, such as DNA or RNA or fragments thereof, including plasmid DNA, genomic DNA, bacterial DNA, viral DNA and any other DNA, and for automated systems, automated devices, automated cartridges and automated methods for processing, separation and purification of proteins, peptides and the like.
Abstract translation: 本发明提供了用于自动化生物处理的系统,装置,装置和方法。 适用于本发明的方案和生物处理方法的实例包括但不限于免疫沉淀,染色质免疫沉淀,重组蛋白分离,核酸分离和分离,蛋白质标记,分离和分离,细胞分离和分离,食品安全分析和自动珠 基于分离。 在一些实施方案中,本发明提供自动化系统,自动化装置,自动化盒和western印迹处理的自动化方法。 其他实施方案包括自动化系统,自动化装置,自动化盒和用于分离,制备和纯化核酸例如DNA或RNA或其片段的自动化方法,包括质粒DNA,基因组DNA,细菌DNA,病毒DNA和任何其它DNA, 以及用于自动化系统,自动化设备,自动化盒和用于处理,分离和纯化蛋白质,肽等的自动化盒和自动化方法。
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公开(公告)号:US11235323B2
公开(公告)日:2022-02-01
申请号:US16557192
申请日:2019-08-30
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Joseph Amshey , Daniel Bezdek , Espir Kahatt , Alexander Khorlin , Lance Parsons , Todd Peterson , Timothy Powers , Michael Thacker , Timothy Updyke , Kornelija Zgonc
Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing. Other embodiments include automated systems, automated devices, automated cartridges and automated methods for separation, preparation and purification of nucleic acids, such as DNA or RNA or fragments thereof, including plasmid DNA, genomic DNA, bacterial DNA, viral DNA and any other DNA, and for automated systems, automated devices, automated cartridges and automated methods for processing, separation and purification of proteins, peptides and the like.
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公开(公告)号:US09808799B2
公开(公告)日:2017-11-07
申请号:US14462640
申请日:2014-08-19
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Joseph Amshey , Daniel Bezdek , Espir Kahatt , Alexander Khorlin , Lance Parsons , Todd Peterson , Timothy Powers , Michael Thacker , Timothy Updyke , Kornelija Zgonc
CPC classification number: B01L3/502715 , B01L3/50273 , B01L7/00 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0689 , B01L2200/10 , B01L2200/16 , B01L2300/0636 , B01L2300/0681 , B01L2300/0867 , B01L2300/088 , B01L2300/123 , B01L2400/0481 , B01L2400/0487 , B01L2400/0605 , B01L2400/0655 , G01N2035/00306 , G01N2035/1037 , Y10T436/2575
Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing. Other embodiments include automated systems, automated devices, automated cartridges and automated methods for separation, preparation and purification of nucleic acids, such as DNA or RNA or fragments thereof, including plasmid DNA, genomic DNA, bacterial DNA, viral DNA and any other DNA, and for automated systems, automated devices, automated cartridges and automated methods for processing, separation and purification of proteins, peptides and the like.
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公开(公告)号:US20170176385A1
公开(公告)日:2017-06-22
申请号:US15124168
申请日:2015-03-06
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Ian Walton , Achim Karger , Alexander Khorlin , Michael Simon , Adam Sannicandro , Alexander Dukhovny , Robert Cobene , Dan Kline , John Dixon
IPC: G01N27/447
CPC classification number: G01N27/44791 , G01N27/44704 , G01N27/44743 , G01N27/44756
Abstract: The present disclosure relates, in some embodiments, to an apparatus for conducting a capillary electrophoresis assay. The apparatus can comprise a capillary array comprising an anode end and a cathode end, the capillary array provided in a housing further comprising a reservoir configured to house a separation medium and an anode buffer. The system can also comprise an injection mechanism configured to deliver sample to the cathode end of the capillary array, and a temperature control zone, wherein the temperature control zone is configured to control the temperature of the interior of the housing.
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公开(公告)号:US10434509B2
公开(公告)日:2019-10-08
申请号:US15719130
申请日:2017-09-28
Applicant: Life Technologies Corporation
Inventor: Joseph Amshey , Daniel Bezdek , Espir Kahatt , Alexander Khorlin , Lance Parsons , Todd Peterson , Timothy Powers , Michael Thacker , Timothy Updyke , Kornelija Zgonc
Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing. Other embodiments include automated systems, automated devices, automated cartridges and automated methods for separation, preparation and purification of nucleic acids, such as DNA or RNA or fragments thereof, including plasmid DNA, genomic DNA, bacterial DNA, viral DNA and any other DNA, and for automated systems, automated devices, automated cartridges and automated methods for processing, separation and purification of proteins, peptides and the like.
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