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公开(公告)号：US20210292857A1
公开(公告)日：2021-09-23
申请号：US17320659
申请日：2021-05-14
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Kelly LI , Ioanna PAGANI , Pius BRZOSKA , Jisheng LI , Chunling WANG , Kathleen HAYASHIBARA , Michael TANNER , Hong JI , Kamini VARMA , Fangqi HU , Robert TEBBS
IPC: C12Q1/70
Abstract: Compositions, assays, methods, diagnostic methods, kits, and diagnostic kits are disclosed for the specific and differential detection of SARS-CoV-2 and/or other viruses from samples, including veterinary samples, clinical samples, food samples, forensic sample, environmental samples (e.g., obtained from soil, garbage, sewage, air, water, food processing and manufacturing surfaces, or likewise), or biological sample obtained from a human or non-human animal.
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2.发明申请METHODS, COMPOSITIONS, SYSTEMS, APPARATUSES AND KITS FOR NUCLEIC ACID AMPLIFICATION 有权方法，组成，系统，核酸放大的装置和工具公开(公告)号：US20130203607A1
公开(公告)日：2013-08-08
申请号：US13828049
申请日：2013-03-14
Applicant: Life Technologies Corporation
Inventor： Bin LI , Kai Qin LAO , Jennifer O'NEIL , Jennifer KUNKEL , Kellie HALEY , Rachel KASINSKAS , Zhaochun MA , Pius BRZOSKA
IPC: C12Q1/68
CPC classification number: C12Q1/6853 , C12Q1/6874 , C12Q2521/531 , C12Q2525/117 , C12Q2535/119 , C12Q2523/313
Abstract: In some embodiments, the present teachings provide methods for paired end sequencing. In some embodiment, a polynucleotide template to be subjected to paired end sequencing comprises at least one cross linking moiety and at least one scissile moiety. In some embodiments, a paired end sequencing reaction comprises (a) a forward sequencing step, (b) a cleavage step, and (c) a reverse sequencing step. In some embodiments, a paired end sequencing reaction comprises (a) a forward sequencing step, (b) a cross-linking step, (c) a cleavage step, and (d) a reverse sequencing step.
Abstract translation: 在一些实施方案中，本教导提供了用于配对末端测序的方法。 在一些实施方案中，待进行配对末端测序的多核苷酸模板包含至少一个交联部分和至少一个可剪切部分。 在一些实施方案中，配对末端测序反应包括（a）正向测序步骤，（b）切割步骤，和（c）反向测序步骤。 在一些实施方案中，配对末端测序反应包括（a）正向测序步骤，（b）交联步骤，（c）切割步骤和（d）反向测序步骤。
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公开(公告)号：US20200075129A1
公开(公告)日：2020-03-05
申请号：US16553993
申请日：2019-08-28
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Daqing WANG , Pius BRZOSKA , Elliot SHELTON
Abstract: A quality control system for a qPCR receives signals resulting from operation of the qPCR system on an assay, and applies labeled data sets to a Support Vector Machine (SVM) to generate classifications for the signals to generate classifications that are utilized as operational feedback to the qPCR system.
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4.发明申请公开(公告)号：US20170067098A1
公开(公告)日：2017-03-09
申请号：US15276713
申请日：2016-09-26
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Bin LI , Kai Qin LAO , Jennifer O'NEIL , Jennifer KUNKEL , Kellie HALEY , Rachel KASINSKAS , Zhaochun MA , Pius BRZOSKA
CPC classification number: C12Q1/6853 , C12P19/34 , C12Q1/46 , C12Q1/6834 , C12Q1/6846 , C12Q1/6869 , C12Q1/6874 , C12Q2531/119 , C12Q2565/537
Abstract: Novel methods of generating a localized population of immobilized clonal amplicons on a support are provided.
Abstract translation: 提供了在载体上产生固定化克隆扩增子的局部群体的新方法。
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公开(公告)号：US20210292856A1
公开(公告)日：2021-09-23
申请号：US17249071
申请日：2021-02-18
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Kelly LI , Ioanna PAGANI , Pius BRZOSKA , Jisheng LI , Chunling WANG , Kathleen HAYASHIBARA , Michael TANNER , Hong JI , Kamini VARMA , Fangqi HU , Robert TEBBS
IPC: C12Q1/70
Abstract: Compositions, assays, methods, diagnostic methods, kits, and diagnostic kits are disclosed for the specific and differential detection of SARS-CoV-2 and/or other viruses from samples, including veterinary samples, clinical samples, food samples, forensic sample, environmental samples (e.g., obtained from soil, garbage, sewage, air, water, food processing and manufacturing surfaces, or likewise), or biological sample obtained from a human or non-human animal.
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Patent Agency Ranking
公开(公告)号：US20200248239A1
公开(公告)日：2020-08-06
申请号：US16856036
申请日：2020-04-23
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Ioanna PAGANI , Pius BRZOSKA , Kelly LI , Sunali PATEL , Boli HUANG , Kamini VARMA , Nitin PURI , Evan DIAMOND
IPC: C12Q1/689 , C12Q1/6888 , C12Q1/6895
Abstract: Methods, compositions and kits for detecting microorganisms and/or profiling microbiota such as for example through use of nucleic acid amplification and detection.
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7.发明申请公开(公告)号：US20150275284A1
公开(公告)日：2015-10-01
申请号：US14692706
申请日：2015-04-21
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Bin LI , Kai Qin LAO , Jennifer O'NEIL , Jennifer KUNKEL , Kellie HALEY , Rachel KASINSKAS , Zhaochun MA , Pius BRZOSKA
IPC: C12Q1/68
CPC classification number: C12Q1/46 , C12P19/34 , C12Q1/6834 , C12Q1/6846 , C12Q1/6853 , C12Q1/6869 , C12Q1/6874 , C12Q2531/119 , C12Q2565/537
Abstract: Novel methods of generating a localized population of immobilized clonal amplicons on a support are provided.
Abstract translation: 提供了在载体上产生固定化克隆扩增子的局部群体的新方法。
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公开(公告)号：US20240263247A1
公开(公告)日：2024-08-08
申请号：US18635799
申请日：2024-04-15
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： David MERRILL , Pius BRZOSKA , Zheng LI , Wendy LIN , Wing LEE , Mandi WONG
IPC: C12Q1/6886 , C12Q1/6851 , C12Q1/6858
CPC classification number: C12Q1/6886 , C12Q1/6851 , C12Q1/6858 , C12Q2600/156 , C12Q2600/158 , C12Q2600/166
Abstract: Disclosed herein is a method including one or more of amplifying a nucleic acid sequence of interest in a sample comprising genomic DNA of a subject; amplifying a reference nucleic acid sequence in the sample; quantifying the amplified sequence of interest relative to the amplified reference sequence; and determining a copy number of the sequence of interest from the relative quantified amplified sequence of interest. The reference sequence can have at least 80% sequence identity to at least one of SEQ ID NO:1-38. Also disclosed are kits, systems and compositions that can include a first probe which specifically hybridizes to at least a portion of at least one reference sequence.
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公开(公告)号：US20230175051A1
公开(公告)日：2023-06-08
申请号：US18104548
申请日：2023-02-01
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Bin Li , Kai Qin LAO , Jennifer O'NEIL , Jennifer KUNKEL , Kellie HALEY , Rachel KASINSKAS , Zhaochun MA , Pius BRZOSKA
IPC: C12Q1/6853 , C12Q1/6844 , C12Q1/6806 , C12P19/34 , C12Q1/6869 , C12Q1/6874 , C12Q1/6834 , C12Q1/46
CPC classification number: C12Q1/6853 , C12Q1/6846 , C12Q1/6806 , C12P19/34 , C12Q1/6869 , C12Q1/6874 , C12Q1/6834 , C12Q1/46 , C12Q2531/119 , C12Q2565/537
Abstract: Novel methods of generating a localized population of immobilized clonal amplicons on a support are provided.
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公开(公告)号：US20220186328A1
公开(公告)日：2022-06-16
申请号：US17567411
申请日：2022-01-03
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Kelly LI , Ioanna PAGANI , Pius BRZOSKA , Jisheng LI , Chunling WANG , Kathleen HAYASHIBARA , Michael TANNER , Hong JI , Kamini VARMA , Fangqi HU , Robert TEBBS
IPC: C12Q1/70
Abstract: Compositions, assays, methods, diagnostic methods, kits, and diagnostic kits are disclosed for the specific and differential detection of SARS-CoV-2 and/or other viruses from samples, including veterinary samples, clinical samples, food samples, forensic sample, environmental samples (e.g., obtained from soil, garbage, sewage, air, water, food processing and manufacturing surfaces, or likewise), or biological sample obtained from a human or non-human animal.
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