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公开(公告)号：US08469194B2
公开(公告)日：2013-06-25
申请号：US12917725
申请日：2010-11-02
申请人： Larry Johnson , Robert J. Crawford
发明人： Larry Johnson , Robert J. Crawford
CPC分类号： B65D83/049 , A61J1/03 , A61J7/0076 , B65D51/22 , B65D51/24 , B65D83/0481
摘要： Aspects of the disclosure involve a pill-filtering article that is located and secured inside a pill container. Using one system, an assembly of articles distributes one pill at a time in the form of a single-pill dispensing apparatus that includes a pill-storage container and such a pill-filtering article. The container has an inner wall, an upper portion with a rim region where a cap may be secured, and a lower portion for containing pills. The pill-filtering article has a size and a shape that facilitates securing the article inside the pill-storage container near the inner wall, above the lower portion, and below the upper rim region, and also configured with a plurality of channel-defining regions including a first channel-defining region through which one-pill at a time passes and including a second channel-defining region through which one pill at a time passes.
摘要翻译： 本公开的方面涉及一种药丸过滤制品，其定位并固定在药丸容器内。 使用一个系统，制品的组件一次分配一个药丸，其形式为单药丸分配装置，其包括药丸储存容器和这种药丸过滤制品。 容器具有内壁，具有可以固定帽的边缘区域的上部和用于容纳药丸的下部。 丸剂过滤制品具有便于将物品固定在药丸储存容器内部靠近内壁，下部上方和上缘区域下方的尺寸和形状，并且还配置有多个通道限定区域 包括第一通道限定区域，一次一片通过该区域，并且包括一次通过一个药丸的第二通道限定区域。
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公开(公告)号：US20120024880A1
公开(公告)日：2012-02-02
申请号：US12917725
申请日：2010-11-02
申请人： Larry Johnson , Robert J. Crawford
发明人： Larry Johnson , Robert J. Crawford
CPC分类号： B65D83/049 , A61J1/03 , A61J7/0076 , B65D51/22 , B65D51/24 , B65D83/0481
摘要： Aspects of the disclosure are implemented using a variety of systems and methods involving pill-filtering article that is located and secured inside a pill container. Using one such system, an assembly of articles distributes one pill at a time in the form of a single-pill dispensing apparatus that includes a pill-storage container and such a pill-filtering article. The pill-storage container has an inner wall, an upper portion with a rim region at which a cap may be secured to the pill-storage container, and a lower portion configured for containing pills. The pill-filtering article is configured with a size and a shape that facilitates securing the article inside the pill-storage container near the inner wall, above the lower portion, and below the upper rim region, and also configured with a plurality of channel-defining regions including a first channel-defining region through which one-pill at a time passes and including a second channel-defining region through which one pill at a time passes. Each of the plurality of channel-defining regions region is respectively configured and arranged to facilitate a modification that results in formation of an aperture near a boundary of the channel-defining region for passing one pill at a time, and to pass pills that are of different types in terms of at least one of size and shape. In this regard, when only one of the plurality of channel-defining regions is modified, the pill-filtering article permits only one pill at a time to pass, through the aperture ensuing from the modification, from the lower portion of the container to the upper portion of the container.
摘要翻译： 本公开的方面使用涉及药丸过滤制品的各种系统和方法来实现，该制品和方法位于并固定在药丸容器内。 使用一个这样的系统，制品的组合一次分配一个药丸，其形式为单药丸分配装置，其包括药丸储存容器和这种药丸过滤制品。 药丸储存容器具有内壁，具有边缘区域的上部，盖子可以固定在药丸储存容器上，下部构造成用于容纳药丸。 药丸过滤制品具有容易将物品固定在药剂储存容器内部靠近内壁，下部上方和下缘部下方的尺寸和形状，并且还配置有多个通道 - 限定区域，包括第一通道限定区域，一次一片通过该区域，并且包括一次一个药片通过的第二通道限定区域。 多个通道限定区域区域中的每一个分别被配置和布置成有助于导致在通道限定区域的边界附近形成孔的修改，以便一次通过一个药片，并且通过药丸 在尺寸和形状中的至少一个方面不同的类型。 在这方面，当多个通道限定区域中的仅一个被修改时，药丸过滤制品每次只能允许一个药片通过从改型的接着的孔口从容器的下部到达 容器的上部。
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公开(公告)号：US09469300B1
公开(公告)日：2016-10-18
申请号：US14608673
申请日：2015-01-29
申请人： Robert J. Crawford
发明人： Robert J. Crawford
CPC分类号： B60W30/143 , B60W2540/30 , B60W2550/14 , B60W2550/143 , B60W2720/10
摘要： Aspects of the present disclosure are directed towards hysteresis engaged vehicle cruise control apparatuses, and systems and methods that facilitate energy efficiency as a function of external energy obstacles. The method and system includes an adaptable terrain-based speed profile and terrain-based work function for maintaining a vehicle at a desired speed and selected speed range. The speed profile further includes a terrain-based driving preference associated with an identifier that identifies a particular driver and driving profile. Vehicle-related data is generated with regard to energy efficiency obstacles, and vehicle speed is automatically adjusted based on this data to facilitate fuel economy. In certain embodiments, vehicle-related data is sent to a cloud-computing system for processing. In other embodiments, the desired speed and terrain-based speed profile is influenced by user or external inputs.
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公开(公告)号：US20100023428A1
公开(公告)日：2010-01-28
申请号：US12569622
申请日：2009-09-29
CPC分类号： G06Q30/0643 , G06F17/30893 , G06Q30/0222 , G06Q30/0229 , G06Q30/0253 , G06Q30/0254 , G06Q30/0255 , G06Q30/0256 , G06Q30/0269 , G06Q30/0273 , G06Q30/0283 , G06Q30/04 , G06Q30/06 , G06Q30/0601 , G06Q30/0631 , G06Q30/0633 , G06Q30/0641
摘要： An image data processing method involves on-line viewing of a first article through a linking node for virtual merging on another structure. A particular application of the invention is directed to on-line apparel shopping involving a shopping basket. For example, on-line viewing of one article, such as clothing, on another structure, includes creating an item from image-data corresponding to an article selected by an on-line viewer and tagged as a prospective selection via a shopping basket designation with an image of a structure selected by the on-line viewer.
摘要翻译： 图像数据处理方法涉及通过链接节点在线观看第一物品以便在另一结构上进行虚拟合并。 本发明的具体应用涉及涉及购物篮的在线服装购物。 例如，在另一结构上的一件物品（例如衣服）的在线观看包括从对应于在线观看者选择的物品的图像数据创建物品，并通过购物篮指定将其标记为预期选择， 由在线观看者选择的结构的图像。
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5.发明授权Materials and methods for management of hyperacute rejection in human xenotransplantation 有权用于人类异种移植中超急性排斥反应的材料和方法公开(公告)号：US07201899B2
公开(公告)日：2007-04-10
申请号：US10762888
申请日：2004-01-21
申请人： Anthony J. F. d′Apice , Martin J. Pearse , Allan J. Robins , Robert J. Crawford , Peter D. Rathjen
发明人： Anthony J. F. d′Apice , Martin J. Pearse , Allan J. Robins , Robert J. Crawford , Peter D. Rathjen
CPC分类号： A61K31/7004 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2227/108 , A01K2267/02 , A01K2267/025 , A01K2267/03 , A61K31/70 , A61K38/00 , C07K14/54 , C07K16/40 , C12N9/1051 , C12N15/8509 , C12N2800/30
摘要： Human pre-formed xenoantibodies play an important role in the hyperacute rejection response in human xenotransplantation. Disclosed are materials and methods for removing or neutralizing such antibodies. Also disclosed are materials and methods for reducing or eliminating the epitopes in the donor organs that are recognized by such antibodies. Such epitopes are formed as the result of activity by the enzyme α-1,3 galactosyltransferase. The porcine gene encoding α-1,3 galactosyltransferase is disclosed, as are materials and methods for inactivating (“knocking out”) the α-1,3 galactosyltransferase gene in mammalian cells and embryos. Included are nucleic acid constructs useful for inactivating the α-1,3 galactosyltransferase gene in a target cell. Also disclosed is a novel leukemia inhibitory factor (T-LIF) that is useful for maintenance of embryonic stem cells and primordial germ cells in culture.
摘要翻译： 人类预先形成的异种抗体在人异种移植中的超急性排斥反应中起重要作用。 公开了用于去除或中和此类抗体的材料和方法。 还公开了用于减少或消除由这种抗体识别的供体器官中的表位的材料和方法。 作为α-1,3半乳糖转移酶活性的结果形成这样的表位。 公开了编码α-1,3半乳糖基转移酶的猪基因，以及在哺乳动物细胞和胚胎中灭活（“敲除”）α-1,3半乳糖基转移酶基因的材料和方法。 包括可用于灭活靶细胞中的α-1,3半乳糖基转移酶基因的核酸构建体。 还公开了一种新颖的白血病抑制因子（T-LIF），其可用于维持培养中的胚胎干细胞和原始生殖细胞。
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公开(公告)号：US06300979B1
公开(公告)日：2001-10-09
申请号：US08868703
申请日：1997-06-04
IPC分类号： H04N5225
CPC分类号： F16M13/02 , F16M11/08 , F16M11/24 , Y10S248/918
摘要： A device for mounting a structure, such as a video camera, on a support includes a base and an arm projecting from the base. The video camera rests on one surface of the base and another surface rests on the support. The arm is adapted for insertion into a recessed cavity in the support, such as an antenna hole in a television set to provide a stable mounting device for the video camera. The angle of the video camera can be altered by pivoting the camera around the arm.
摘要翻译： 用于将诸如摄像机的结构安装在支撑件上的装置包括从基座突出的底座和臂。 摄像机放置在底座的一个表面上，另一个表面放置在支架上。 该臂适于插入到支撑件中的凹腔中，例如电视机中的天线孔，以为摄像机提供稳定的安装装置。 可以通过围绕手臂旋转摄像机来改变摄像机的角度。
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公开(公告)号：USD448303S1
公开(公告)日：2001-09-25
申请号：US29118632
申请日：2000-02-11
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8.发明授权Mice homozygous for an inactivated .alpha. 1,3-galactosyl transferase gene 失效对于失活的α1,3-半乳糖基转移酶基因是纯合的小鼠
公开(公告)号：US5849991A
公开(公告)日：1998-12-15
申请号：US378617
申请日：1995-01-26
申请人： Anthony J. F. d'Apice , Martin J. Pearse , Allan J. Robins , Robert J. Crawford , Peter D. Rathjen
发明人： Anthony J. F. d'Apice , Martin J. Pearse , Allan J. Robins , Robert J. Crawford , Peter D. Rathjen
IPC分类号： A01K67/027 , A61K31/70 , A61K38/00 , C07K1/22 , C07K14/47 , C07K14/54 , C07K16/40 , C07K16/44 , C12N5/10 , C12N9/10 , C12N15/09 , C12N15/54 , C12N15/85 , C12N5/00 , C12N15/00
CPC分类号： A61K31/7004 , A01K67/0276 , A61K31/70 , C07K14/54 , C07K16/40 , C12N15/8509 , C12N9/1051 , A01K2217/075 , A01K2227/105 , A01K2227/108 , A01K2267/02 , A01K2267/025 , A01K2267/03 , A61K38/00 , C12N2800/30
摘要： Human pre-formed xenoantibodies play an important role in the hyperacute rejection response in human xenotransplantation. Disclosed are materials and methods for removing or neutralizing such antibodies. Also disclosed are materials and methods for reducing or eliminating the epitopes in the donor organs that are recognized by such antibodies. Such epitopes are formed as the result of activity by the enzyme .alpha.-1,3 galactosyltransferase. The porcine gene encoding .alpha.-1,3 galactosyltransferase is disclosed, as are materials and methods for inactivating ("knocking out") the .alpha.-1,3 galactosyltransferase gene in mammalian cells and embryos. Included are nucleic acid constructs useful for inactivating the .alpha.-1,3 galactosyltransferase gene in a target cell. Also disclosed is a novel leukemia inhibitory factor (T-LIF) that is useful for maintenance of embryonic stem cells and primordial germ cells in culture.
摘要翻译： 人类预先形成的异种抗体在人异种移植中的超急性排斥反应中起重要作用。 公开了用于去除或中和此类抗体的材料和方法。 还公开了用于减少或消除由这种抗体识别的供体器官中的表位的材料和方法。 这种表位是由酶α-1,3-半乳糖基转移酶活性的结果形成的。 公开了编码α-1,3-半乳糖基转移酶的猪基因，以及在哺乳动物细胞和胚胎中灭活（“敲除”）α-1,3-半乳糖基转移酶基因的材料和方法。 包括可用于灭活靶细胞中的α-1,3半乳糖基转移酶基因的核酸构建体。 还公开了一种新颖的白血病抑制因子（T-LIF），其可用于维持培养中的胚胎干细胞和原始生殖细胞。
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公开(公告)号：US4229364A
公开(公告)日：1980-10-21
申请号：US38594
申请日：1979-05-14
申请人： Robert J. Crawford
发明人： Robert J. Crawford
IPC分类号： C07C255/31 , B01J23/46 , C07B61/00 , C07C67/00 , C07C253/00 , C07C255/45 , C07C120/00 , C07C121/48
CPC分类号： C07C255/45
摘要： 1,4-Bis(dicyanomethylene)cyclohexane is the chemical of choice for the synthesis of TCNQ. The present invention provides a simple convenient, three-step synthesis of 1,4-bis(dicyanomethylene)cyclohexane from hydroquinone which uses water as the reaction solvent.
摘要翻译： 1,4-二（二氰基亚甲基）环己烷是合成TCNQ的首选化学物质。 本发明提供使用水作为反应溶剂的氢醌的简单方便的三步合成1,4-双（二氰基亚甲基）环己烷。
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10.发明授权公开(公告)号：US09990672B2
公开(公告)日：2018-06-05
申请号：US12568495
申请日：2009-09-28
CPC分类号： G06Q30/0643 , G06F17/30893 , G06Q30/0222 , G06Q30/0229 , G06Q30/0253 , G06Q30/0254 , G06Q30/0255 , G06Q30/0256 , G06Q30/0269 , G06Q30/0273 , G06Q30/0283 , G06Q30/04 , G06Q30/06 , G06Q30/0601 , G06Q30/0631 , G06Q30/0633 , G06Q30/0641
摘要： An e-commerce method involves on-line viewing of a first article through a linking node for virtual merging on another structure. A particular application of the invention is directed to on-line apparel shopping involving a color matching scheme using color codes provided with images to be merged. For example, on-line viewing of one article, such as clothing, on another structure, includes creating an item from image-data corresponding to a colored article selected by an on-line viewer from an on-line viewer site with an image of a colored structure selected by the on-line viewer, and indicating whether the colored article and the colored structure satisfy a color-matching criterion.
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