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    Medical devices with local drug delivery capabilities
    1.
    发明申请
    Medical devices with local drug delivery capabilities 有权
    具有局部药物输送能力的医疗器械

    公开(公告)号：US20070225564A1

    公开(公告)日：2007-09-27

    申请号：US11390401

    申请日：2006-03-27

    申请人： Lucien Couvillon ,  Michael Banik ,  (Samuel) Zhong

    发明人： Lucien Couvillon ,  Michael Banik ,  (Samuel) Zhong

    IPC分类号： A61B1/00

    CPC分类号： A61B1/012 ,  A61B1/2736 ,  A61B1/31 ,  A61B5/4839 ,  A61M2025/0057 ,  A61N1/306

    摘要： A medical device, for example, an endoscope or catheter, includes local drug delivery capabilities for selectively delivering at least one drug in vivo. The local drug delivery may occur as the medical device is advanced through tortuous passageways of the patient's body or may occur after the medical device has reached its targeted destination. The medical device includes a drug agent, for example, carried in or on a hydrophilic or hydrogel coating disposed on the outside thereof. When the hydrogel or drug agent receives an appropriate signal, e.g., solution containing a triggering agent or triggering condition, e.g., heat or light, the hydrogel contracts or expands to squeeze out the drug from hydrogel. If electric current is provided as the signal, and the drug agent is charged, the drug agent is released by electrophoretic forces.

    摘要翻译： 医疗装置，例如内窥镜或导管，包括用于在体内选择性递送至少一种药物的局部药物递送能力。 当医疗设备通过患者身体的曲折通道前进时，可能发生局部药物递送，或者可能在医疗设备到达目的地之后发生。 医疗装置包括例如携带在设置在其外侧的亲水或水凝胶涂层中的药剂。 当水凝胶或药剂接收适当的信号，例如含有引发剂或触发条件（例如热或轻）的溶液时，水凝胶收缩或膨胀以从水凝胶中挤出药物。 如果提供电流作为信号，并且药剂被充电，则药物通过电泳力释放。

    Robotic endoscope with wireless interface
    5.
    发明申请
    Robotic endoscope with wireless interface 有权
    机器人内窥镜带无线接口

    公开(公告)号：US20050065400A1

    公开(公告)日：2005-03-24

    申请号：US10909921

    申请日：2004-08-02

    申请人： Michael Banik ,  Lucien Couvillon

    发明人： Michael Banik ,  Lucien Couvillon

    IPC分类号： G02B23/24 ,  A61B1/00 ,  A61B1/005 ,  A61B1/05 ,  A61B1/04

    CPC分类号： A61B1/00059 ,  A61B1/00103 ,  A61B1/0053 ,  A61B1/0055 ,  A61B1/0058 ,  A61B1/2736 ,  A61M2025/0058 ,  G06F19/00 ,  G06Q10/06 ,  G06Q10/08 ,  G06Q50/22 ,  G06Q50/28 ,  G16H40/63

    摘要： An endoscope apparatus and method of operating the same. The endoscope apparatus comprises an endoscope portion and a control and display unit. The endoscope portion preferably comprises: (i) a sensor disposed at a distal end of the endoscope portion and providing endoscope data; (ii) one or more electronically controlled actuators (e.g., electroactive polymer actuators) controlling the operation of the endoscope portion based on received control signals; (iii) a first wireless transceiver coupled to the sensor and the one or more electronically controlled actuators, transmitting received endoscope data from the sensor and forwarding received control signals to the one or more electronically controlled actuators; and (iv) a portable power source (e.g., a battery) coupled to the sensor, the first wireless transceiver, and the one or more electronically controller actuators. The control and display unit preferably comprises: (i) a second wireless transceiver coupled via a wireless link to the first transceiver in the endoscope portion and receiving endoscope data from the first transceiver and transmitting control signals to the first transceiver; (ii) a control portion coupled to the second wireless transceiver and sending control signals to the one or more actuators in the endoscope portion via the first and second wireless transceivers; and (iii) a display portion that displays information received from the sensor via the first and second wireless transceivers. Another aspect of the present invention is directed to a method for providing single-use endoscopes to one or more hospitals.

    摘要翻译： 一种内窥镜装置及其操作方法。 内窥镜装置包括内窥镜部和控制显示部。 内窥镜部优选包括：（i）设置在内窥镜部的前端的传感器，提供内窥镜数据; （ii）基于接收到的控制信号控制内窥镜部分的操作的一个或多个电子控制致动器（例如电活性聚合物致动器）; （iii）耦合到所述传感器和所述一个或多个电子控制致动器的第一无线收发器，从所述传感器发送所接收的内窥镜数据并将接收的控制信号转发到所述一个或多个电子控制致动器; 和（iv）耦合到传感器，第一无线收发器和一个或多个电子控制器致动器的便携式电源（例如，电池）。 控制和显示单元优选地包括：（i）经由无线链路耦合到内窥镜部分中的第一收发器的第二无线收发器，并且从第一收发器接收内窥镜数据并向第一收发器发送控制信号; （ii）耦合到所述第二无线收发器的控制部分，经由所述第一和第二无线收发器向所述内窥镜部分中的所述一个或多个致动器发送控制信号; 和（iii）经由第一和第二无线收发器显示从传感器接收的信息的显示部分。 本发明的另一方面涉及一种用于向一个或多个医院提供一次性内窥镜的方法。

    Robotic endoscope with wireless interface
    6.
    发明申请
    Robotic endoscope with wireless interface 有权

    公开(公告)号：US20060293563A1

    公开(公告)日：2006-12-28

    申请号：US11511806

    申请日：2006-08-29

    申请人： Michael Banik ,  Lucien Couvillon

    发明人： Michael Banik ,  Lucien Couvillon

    IPC分类号： A61B1/00

    CPC分类号： A61B1/00059 ,  A61B1/00103 ,  A61B1/0053 ,  A61B1/0055 ,  A61B1/0058 ,  A61B1/2736 ,  A61M2025/0058 ,  G06F19/00 ,  G06Q10/06 ,  G06Q10/08 ,  G06Q50/22 ,  G06Q50/28 ,  G16H40/63

    摘要： An endoscope apparatus and method of operating the same. The endoscope apparatus comprises an endoscope portion and a control and display unit. The endoscope portion preferably comprises: (i) a sensor disposed at a distal end of the endoscope portion and providing endoscope data; (ii) one or more electronically controlled actuators (e.g., electroactive polymer actuators) controlling the operation of the endoscope portion based on received control signals; (iii) a first wireless transceiver coupled to the sensor and the one or more electronically controlled actuators, transmitting received endoscope data from the sensor and forwarding received control signals to the one or more electronically controlled actuators; and (iv) a portable power source (e.g., a battery) coupled to the sensor, the first wireless transceiver, and the one or more electronically controller actuators. The control and display unit preferably comprises: (i) a second wireless transceiver coupled via a wireless link to the first transceiver in the endoscope portion and receiving endoscope data from the first transceiver and transmitting control signals to the first transceiver; (ii) a control portion coupled to the second wireless transceiver and sending control signals to the one or more actuators in the endoscope portion via the first and second wireless transceivers; and (iii) a display portion that displays information received from the sensor via the first and second wireless transceivers. Another aspect of the present invention is directed to a method for providing single-use endoscopes to one or more hospitals.

    Device with enhanced indication of use and prevention of re-use
    7.
    发明申请
    Device with enhanced indication of use and prevention of re-use 审中-公开
    具有增强的使用指示和防止再次使用的装置

    公开(公告)号：US20060069305A1

    公开(公告)日：2006-03-30

    申请号：US10955905

    申请日：2004-09-30

    申请人： Lucien Couvillon ,  Sheng-Ping Zhong ,  Michael Banik ,  Ronald Sahatjian

    发明人： Lucien Couvillon ,  Sheng-Ping Zhong ,  Michael Banik ,  Ronald Sahatjian

    IPC分类号： A61B1/00 ,  A61B17/00

    CPC分类号： A61B1/00055 ,  A61B1/00062 ,  A61B1/00103 ,  A61B2090/0814 ,  A61B2560/0276

    摘要： In one aspect, the present invention is a medical device that reduces the likelihood of an operator improperly reusing it. The medical device includes (a) a device body; (b) a substrate comprising a contrast material that covers at least a portion of the device body; and (c) an outer layer comprising a hydrophilic material that covers at least a portion of the substrate. The outer layer comprising hydrophilic material is capable of absorbing water-soluble contaminants during clinical use that, once absorbed, are visible against the background of the substrate comprising the contrast material. In another aspect, the device includes (a) a device body and (b) an outer layer comprising a usage indicator reagent. In another aspect, the invention provides methods of preventing re-use of a single use medical device.

    摘要翻译： 一方面，本发明是减少操作者不当地重用它的可能性的医疗装置。 医疗装置包括（a）装置主体; （b）包括覆盖所述装置主体的至少一部分的对比材料的基板; 和（c）包含覆盖基材的至少一部分的亲水材料的外层。 包含亲水材料的外层能够在临床使用期间吸收水溶性污染物，其一旦被吸收就可以抵抗包含造影剂材料的底物的背景而可见。 在另一方面，该装置包括（a）装置主体和（b）包含使用指示剂试剂的外层。 在另一方面，本发明提供了防止单次使用的医疗装置的再次使用的方法。

    Endoscope with fiber optic transmission of digital video
    8.
    发明申请
    Endoscope with fiber optic transmission of digital video 审中-公开
    内窥镜与数字视频光纤传输

    公开(公告)号：US20050203338A1

    公开(公告)日：2005-09-15

    申请号：US10798587

    申请日：2004-03-10

    申请人： Lucien Couvillon ,  Michael Banik

    发明人： Lucien Couvillon ,  Michael Banik

    IPC分类号： A61B1/04 ,  A61B1/05

    CPC分类号： A61B1/00013 ,  A61B1/00126 ,  A61B1/051

    摘要： A video endoscope in which the imaging chip at the distal tip is connected to the proximal connector and operator console by an optical fiber. Video data (preferably digital) is impressed on the optical fiber by a pulse-code modulator (PCM) circuit and light emitter with lensing. A small, inexpensive, flexible optical fiber in the endoscope body conveys the PCM optical data to the receiving circuit, preferably via an optical connector at the proximal end of the endoscope, and to decoding and display circuits in the operator console. The fiber optic transmission overcomes the difficulty of electrical transmission of wide band (digital video) signals via miniature cables, which can be expensive, bulky, inflexible, susceptible to noise and interference, and constitute a potential electrical safety risk by leakage currents. The PCM circuits may be integrated into the camera chip.

    摘要翻译： 视频内窥镜，其中远端的成像芯片通过光纤连接到近端连接器和操作员控制台。 通过脉冲编码调制器（PCM）电路和具有透镜的光发射器将视频数据（优选数字）施加在光纤上。 内窥镜主体中的小型廉价柔性光纤优选地经由内窥镜近侧的光连接器将PCM光学数据传送到接收电路，并且在操作员控制台中解码和显示电路。 光纤传输通过微型电缆克服了宽带（数字视频）信号的电传输困难，该电缆可能价格昂贵，体积大，不灵活，容易受到噪声和干扰，并且通过漏电流构成潜在的电气安全风险。 PCM电路可以集成到相机芯片中。

    Medical devices with light emitting regions
    10.
    发明申请
    Medical devices with light emitting regions 审中-公开
    具有发光区域的医疗器械

    公开(公告)号：US20060069313A1

    公开(公告)日：2006-03-30

    申请号：US10955909

    申请日：2004-09-30

    申请人： Lucien Couvillon ,  Michael Banik ,  Stephen Fantone ,  Daniel Orband

    发明人： Lucien Couvillon ,  Michael Banik ,  Stephen Fantone ,  Daniel Orband

    IPC分类号： A61B1/06

    CPC分类号： A61B5/06 ,  A61B5/064

    摘要： A medical device, such as an endoscope 20, constructed in accordance with aspects of the present invention is provided. The endoscope 20 includes an elongated shaft-like body 22 having a proximal end 26 and a distal end 28. The shaft-like body comprises a proximal section 40, an optional articulation section 44, and a distal tip section 48 disposed at the distal end 28 of the shaft body. The endoscope 20 further includes surgical navigation features, such as a plurality of light sources 50 for emitting light, that denote the position, direction, and/or orientation of the endoscope in-vivo as the endoscope is advanced through tortuous passageways of the patient's body.

    摘要翻译： 提供了根据本发明的方面构造的医疗装置，例如内窥镜20。 内窥镜20包括具有近端26和远端28的细长轴状体22。 轴状体包括近端部分40，可选的关节运动部分44和设置在轴体的远端28的远端部分48。 内窥镜20还包括外科导航特征，例如用于发射光的多个光源50，当内窥镜通过患者身体的曲折通道前进时，其表示内窥镜在体内的位置，方向和/或取向 。