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公开(公告)号：US20090299447A1
公开(公告)日：2009-12-03
申请号：US11917992
申请日：2006-06-30
申请人： Marc Jensen , Olivier Colliou , Benedict Costello , Mark Zdeblick , Todd Thompson , George Savage , Andrew Thompson
发明人： Marc Jensen , Olivier Colliou , Benedict Costello , Mark Zdeblick , Todd Thompson , George Savage , Andrew Thompson
IPC分类号： A61N1/05
CPC分类号： A61N1/0587
摘要： Minimally invasive deployable epicardial array devices are provided. The devices include deployable platform comprising two or more effectors, such as sensors and actuators, where the devices are configured to be deployed at an epicardial location via a minimally invasive, e.g., sub-xiphoid approach. In embodiments of the present invention, at least one area of the electrode patch is an electrical control area that comprises a series of effectors, e.g., sensors and/or electrodes. Other embodiments provide localized physical constraint and dynamic mechanical stimulation of the heart to effectuate physical and biological responses. Still other embodiments provide both of these functions. Also provided are methods of using the devices, as well as systems and kits that include the devices.
摘要翻译： 提供微创可部署的心外阵列器件。 这些装置包括包括两个或更多个效应器（诸如传感器和致动器）的可展开平台，其中装置被配置成经由微创例如亚剑突方法部署在心外膜位置。 在本发明的实施例中，电极贴片的至少一个区域是包括一系列效应器例如传感器和/或电极的电控制区域。 其他实施例提供心脏的局部物理约束和动态机械刺激以实现物理和生物反应。 其他实施例提供这两个功能。 还提供了使用这些设备的方法，以及包括设备的系统和套件。
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公开(公告)号：US09883819B2
公开(公告)日：2018-02-06
申请号：US13141048
申请日：2010-01-06
申请人： Marc Jensen , Robert Leichner , Patrick Beaulieu , Kit Yee Au-Yeung , Lawrence Arne , Mark Zdeblick , Andrew Thompson , George Savage , Timothy Robertson , Yashar Behzadi
发明人： Marc Jensen , Robert Leichner , Patrick Beaulieu , Kit Yee Au-Yeung , Lawrence Arne , Mark Zdeblick , Andrew Thompson , George Savage , Timothy Robertson , Yashar Behzadi
CPC分类号： A61B5/073 , A61B5/0002 , A61B5/021 , A61B5/024 , A61B5/1112 , A61B5/486 , A61B5/6833 , G06F19/00 , G06F19/3456 , G06F19/3481 , G16H10/60 , G16H20/00 , G16H20/10 , H04B13/005
摘要： Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.
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3.发明申请Ingestion-Related Biofeedback and Personalized Medical Therapy Method and System 有权摄入相关的生物反馈和个性化医疗治疗方法和系统公开(公告)号：US20110270052A1
公开(公告)日：2011-11-03
申请号：US13141048
申请日：2010-01-06
申请人： Marc Jensen , Robert Leichner , Patrick Beaulieu , Kit Yee Au-Yeung , Lawrence Arne , Mark Zdeblick , Andrew Thompson , George Savage , Timothy Robertson , Yashar Behzadi
发明人： Marc Jensen , Robert Leichner , Patrick Beaulieu , Kit Yee Au-Yeung , Lawrence Arne , Mark Zdeblick , Andrew Thompson , George Savage , Timothy Robertson , Yashar Behzadi
IPC分类号： A61B5/07
CPC分类号： A61B5/073 , A61B5/0002 , A61B5/021 , A61B5/024 , A61B5/1112 , A61B5/486 , A61B5/6833 , G06F19/00 , G06F19/3456 , G06F19/3481 , G16H10/60 , G16H20/00 , G16H20/10 , H04B13/005
摘要： Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.
摘要翻译： 提供了用于获取有助于支持患者实施和遵守医学上规定的治疗方案的信息的方法，装置和系统。 该疗法可以包括生物反馈方法和/或个性化治疗方面。 一种方法包括以下步骤：由接收装置接收与可摄取事件标记相关联的生物特征信息; 通过具有微处理器的计算设备分析生物特征信息; 以及至少部分地基于分析和/或将生物反馈技术集成到患者治疗或活动中来确定治疗推荐。 一种系统包括用于接收与可摄取事件标记相关联的生物特征信息的生物特征信息模块; 分析生物特征信息的分析模块; 以及确定模块，用于至少部分地基于分析来可选地确定和传达治疗推荐。
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公开(公告)号：US08545436B2
公开(公告)日：2013-10-01
申请号：US13336956
申请日：2011-12-23
申请人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
发明人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
IPC分类号： A61M5/168
CPC分类号： A61M5/1723 , A61B5/0006 , A61B5/0028 , A61B5/02055 , A61B5/0404 , A61B5/04085 , A61B5/0428 , A61B5/053 , A61B5/11 , A61B5/1112 , A61B5/145 , A61B5/14532 , A61B5/4094 , A61B2560/0209 , A61B2560/0412 , A61B2560/0468 , A61B2562/0219 , A61M5/1452 , A61M5/172 , G06F19/34 , G06F19/3418 , H04B13/005
摘要： Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.
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公开(公告)号：US08469921B2
公开(公告)日：2013-06-25
申请号：US13336956
申请日：2011-12-23
申请人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
发明人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
IPC分类号： A61M5/16
摘要： Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.
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公开(公告)号：US20100312188A1
公开(公告)日：2010-12-09
申请号：US12673326
申请日：2009-12-15
申请人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
发明人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
CPC分类号： A61M5/1723 , A61B5/0006 , A61B5/0028 , A61B5/02055 , A61B5/0404 , A61B5/04085 , A61B5/0428 , A61B5/053 , A61B5/11 , A61B5/1112 , A61B5/145 , A61B5/14532 , A61B5/4094 , A61B2560/0209 , A61B2560/0412 , A61B2560/0468 , A61B2562/0219 , A61M5/1452 , A61M5/172 , G06F19/34 , G06F19/3418 , H04B13/005
摘要： Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.
摘要翻译： 提供可能是外部或可植入的接收器。 本发明的接收机的方面包括存在一个或多个：高功率低功率模块; 中介模块; 电源模块，被配置为激活和去激活一个或多个电源给高功率处理块; 连接主站和从站的串行外设接口总线; 和多用途连接器。 本发明的接收机可以被配置为接收电传送的信号。 还提供了包括接收器的系统，以及使用它们的方法。 另外公开了使用接收器来配合给药系统的系统和方法。
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公开(公告)号：US20110009715A1
公开(公告)日：2011-01-13
申请号：US12522249
申请日：2009-07-02
申请人： David O' Reilly , Erika Karplus , Andrew Thompson , George Savage , Mark Zdeblick , Timothy Robertson , Lawrence Arne , Yashar Behzadi , Gregory Moon , Patrick Beaulieu
发明人： David O' Reilly , Erika Karplus , Andrew Thompson , George Savage , Mark Zdeblick , Timothy Robertson , Lawrence Arne , Yashar Behzadi , Gregory Moon , Patrick Beaulieu
IPC分类号： A61B5/07
CPC分类号： A61B5/07 , A61B5/0022 , A61B5/021 , G06F19/3418 , G06F19/3456
摘要： The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). The functions and utilities include data and/or information having an aspect of data derived from, collected by, aggregated by, or otherwise associated with, an ingestion event.
摘要翻译： 可摄入事件标记数据框架提供统一的全面框架，以实现与可摄取事件标记数据（IEM数据）相关的各种功能和实用程序。 功能和实用程序包括具有从摄取事件导出，收集，聚合或以其他方式与之相关的数据的方面的数据和/或信息。
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公开(公告)号：US20120101430A1
公开(公告)日：2012-04-26
申请号：US13336956
申请日：2011-12-23
申请人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
发明人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
CPC分类号： A61M5/1723 , A61B5/0006 , A61B5/0028 , A61B5/02055 , A61B5/0404 , A61B5/04085 , A61B5/0428 , A61B5/053 , A61B5/11 , A61B5/1112 , A61B5/145 , A61B5/14532 , A61B5/4094 , A61B2560/0209 , A61B2560/0412 , A61B2560/0468 , A61B2562/0219 , A61M5/1452 , A61M5/172 , G06F19/34 , G06F19/3418 , H04B13/005
摘要： Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.
摘要翻译： 提供可能是外部或可植入的接收器。 本发明的接收机的方面包括存在一个或多个：高功率低功率模块; 中介模块; 电源模块，被配置为激活和去激活一个或多个电源给高功率处理块; 连接主站和从站的串行外设接口总线; 和多用途连接器。 本发明的接收机可以被配置为接收电传送的信号。 还提供了包括接收器的系统，以及使用它们的方法。 另外公开了使用接收器来配合给药系统的系统和方法。
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公开(公告)号：US08114021B2
公开(公告)日：2012-02-14
申请号：US12673326
申请日：2009-12-15
申请人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
发明人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
CPC分类号： A61M5/1723 , A61B5/0006 , A61B5/0028 , A61B5/02055 , A61B5/0404 , A61B5/04085 , A61B5/0428 , A61B5/053 , A61B5/11 , A61B5/1112 , A61B5/145 , A61B5/14532 , A61B5/4094 , A61B2560/0209 , A61B2560/0412 , A61B2560/0468 , A61B2562/0219 , A61M5/1452 , A61M5/172 , G06F19/34 , G06F19/3418 , H04B13/005
摘要： Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.
摘要翻译： 提供可能是外部或可植入的接收器。 本发明的接收机的方面包括存在一个或多个：高功率低功率模块; 中介模块; 电源模块，被配置为激活和去激活一个或多个电源给高功率处理块; 连接主站和从站的串行外设接口总线; 和多用途连接器。 本发明的接收机可以被配置为接收电传送的信号。 还提供了包括接收器的系统，以及使用它们的方法。 另外公开了使用接收器来配合给药系统的系统和方法。
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公开(公告)号：US08674825B2
公开(公告)日：2014-03-18
申请号：US12404184
申请日：2009-03-13
IPC分类号： G08B1/08
CPC分类号： A61B5/073 , A61B5/0028 , A61B5/0031 , A61B5/07 , A61B5/076 , A61B5/1473 , A61B5/4833 , A61B5/4839 , A61B5/681 , A61B5/6861 , A61B5/7282 , A61B2560/0214 , A61B2560/0462 , A61B2562/08 , A61B2562/162 , A61J3/007 , G06F19/00 , G06K7/10168 , H01Q1/273 , Y10T29/49117
摘要： Compositions, systems and methods that allow for the detection of the actual physical delivery of a pharmaceutical agent to a body are provided. Embodiments of the compositions include an identifier and an active agent. The invention finds use in a variety of different applications, including but not limited to, monitoring of therapeutic regimen compliance, tracking the history of pharmaceutical agents, etc.
摘要翻译： 提供了允许检测药物到身体的实际物理输送的组合物，系统和方法。 组合物的实施方案包括标识符和活性剂。 本发明可用于各种不同的应用，包括但不限于监测治疗方案依从性，跟踪药剂的历史等。
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