利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

39 条记录 (耗时 0.034 秒)

    3-aminochroman compounds
    7.
    发明授权
    3-aminochroman compounds 失效
    3-氨基苯并二氢吡喃化合物

    公开(公告)号：US5273994A

    公开(公告)日：1993-12-28

    申请号：US958965

    申请日：1992-10-09

    申请人： Gerald Guillaumet ,  Beatrice Guardiola

    发明人： Gerald Guillaumet ,  Beatrice Guardiola

    IPC分类号： C07D311/58 ,  C07D405/12 ,  C07D498/04 ,  A61K31/47 ,  C07D405/04

    CPC分类号： C07D405/12 ,  C07D311/58

    摘要： The invention relates to the derivatives of general formula (I): ##STR1## in which: Z represents an oxygen atom or a sulfur atom,R.sub.1 represents a hydrogen atom or an alkyl group,R.sub.2 represents a hydrogen atom or an alkyl group,1.ltoreq.n.ltoreq.6,R.sub.3 represents a nitrile group, an optionally substituted amino group or any one of the groups described in the description, andmedicinal products containing the same.

    摘要翻译： 本发明涉及通式（I）的衍生物：其中：Z表示氧原子或硫原子，R1表示氢原子或烷基，R2表示氢原子或烷基 基团，n代表腈基，任选取代的氨基或说明书中所述的任何一个基团，以及含有该基团的药物。

    Analgesic oxazolopyridine compounds
    8.
    发明授权
    Analgesic oxazolopyridine compounds 失效
    镇痛恶唑吡啶化合物

    公开(公告)号：US5061713A

    公开(公告)日：1991-10-29

    申请号：US564033

    申请日：1990-08-07

    申请人： Gerald Guillaumet ,  Christine Flouzat ,  Jacqueline Bonnet

    发明人： Gerald Guillaumet ,  Christine Flouzat ,  Jacqueline Bonnet

    IPC分类号： A61K31/44 ,  A61K31/50 ,  A61K31/505 ,  A61K31/53 ,  A61P25/04 ,  C07D498/04

    CPC分类号： C07D498/04

    摘要： Compound of general formula (I): ##STR1## in which: X, Y, Z and T each represent, independently of one another, a nitrogen atom, a --CH.dbd. group or a group CW, in which W represents a halogen atom or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as a trifluoromethyl group, on condition that only one of them represents a nitrogen atom,Ra, Rb, Rc, Rd and Re represent, independently of one another, a hydrogen atom, a halogen atom or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as a trifluoromethyl group,B represents a hydrogen atom and D a hydroxyl group, or B and D simultaneously represent an oxygen atom,n represents 1 or 2, andR.sub.1 represents a hydrogen atom, a linear or branched lower alkyl, linear or branched lower alkenyl, aryl or lower arylalkyl group or a cycloalkyl group having 3 to 7 carbon atoms, it being possible for each of the lower alkyl, lower alkenyl, aryl, lower arylalkyl and cycloalkyl groups to be substituted with one or more halogen atoms or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as a trifluoromethyl group,their isomers, epimers and diastereoisomers, and addition salts with a pharmaceutically acceptable acidare useful in the treatment of pain.

    摘要翻译： 通式（I）的化合物：其中：X，Y，Z和T​​各自独立地表示氮原子，-CH =基团或基团CW，其中W表示 卤素原子或任选被一个或多个卤素原子取代的低级烷基或烷氧基，例如三氟甲基，条件是只有一个表示氮原子，Ra，Rb，Rc，Rd和Re独立地表示 另一方面，氢原子，卤原子或任选被一个或多个卤素原子取代的低级烷基或烷氧基，例如三氟甲基，B表示氢原子，D表示羟基，或者B和D同时表示 氧原子，n表示1或2，R1表示氢原子，直链或支链的低级烷基，直链或支链的低级烯基，芳基或低级芳基烷基或具有3至7个碳原子的环烷基，每种 的低级烷基，低级烯基，芳基，低级芳基烷基和环亚烷基 被一个或多个卤素原子取代的烷基或任选被一个或多个卤素原子取代的低级烷基或烷氧基，例如三氟甲基，它们的异构体，差向异构体和非对映异构体，以及与药学上可接受的酸的加成盐是有用的 在治疗疼痛。