公开(公告)号：US20060217525A1

公开(公告)日：2006-09-28

申请号：US11316387

申请日：2005-12-21

申请人： Mark Davis ,  Kenneth Wright ,  Ryan Zeidan

发明人： Mark Davis ,  Kenneth Wright ,  Ryan Zeidan

IPC分类号： C08G75/00 ,  C08G79/08 ,  C08G79/02

CPC分类号： A61L27/14 ,  A61K6/08 ,  A61L17/10 ,  A61L17/145 ,  A61L27/34 ,  A61L27/50 ,  A61L27/58 ,  A61L31/10 ,  A61L31/148 ,  C08G63/68 ,  C08G63/688 ,  C08L101/16

摘要： The present invention provides polymers which substantially degrade in the presence of one or more triggers, preferably light energy or hydrogen peroxide, but does not substantially degrade in the absence of one or more triggers.

摘要翻译： 本发明提供了在一种或多种触发剂，优选光能或过氧化氢的存在下基本上降解但在不存在一种或多种触发剂的情况下基本上不降解的聚合物。

公开(公告)号：US20050276841A1

公开(公告)日：2005-12-15

申请号：US11148011

申请日：2005-06-07

申请人： Mark Davis ,  Kenneth Wright ,  Brendan Mack

发明人： Mark Davis ,  Kenneth Wright ,  Brendan Mack

IPC分类号： A61K9/70 ,  A61K31/724 ,  A61K47/48

CPC分类号： B82Y5/00 ,  A61K9/0051 ,  A61K9/0063 ,  A61K9/0092 ,  A61K31/724 ,  A61K47/6951 ,  A61K47/6953

摘要： A sustained-release biodegradable polymeric drug-eluting fiber is disclosed. In some embodiments, the therapeutic drug is complexed with cyclodextrin. In certain embodiments, the polymeric component of the fiber comprises cyclodextrin. The fiber may be fabricated to provide a thread and/or suture. The fiber may be used for treatment of ocular diseases or disorders.

摘要翻译： 公开了一种持续释放的可生物降解的聚合物药物洗脱纤维。 在一些实施方案中，治疗药物与环糊精复合。 在某些实施方案中，纤维的聚合物组分包含环糊精。 纤维可以被制造成提供线和/或缝线。 纤维可用于治疗眼部疾病或病症。

公开(公告)号：US11212380B2

公开(公告)日：2021-12-28

申请号：US16251921

申请日：2019-01-18

申请人： Myron C. Butler ,  Mark Davis

发明人： Myron C. Butler ,  Mark Davis

IPC分类号： H04M1/02 ,  H04M1/18

摘要： Ruggedized voice and data communication systems are disclosed having ruggedized enclosures for housing a communications board with at least one transceiver and a plurality of interfaces. The system has a power supply configured to receive a first voltage and convert the first voltage to a second voltage and provide the second voltage to the communications board.

公开(公告)号：US09177124B2

公开(公告)日：2015-11-03

申请号：US11680530

申请日：2007-02-28

申请人： Muralidhar Krishnaprasad ,  Mark Davis ,  Mark Ture ,  Cindy Hsin ,  Meeten Bhavsar ,  Hiroshi Koide ,  Joaquin Delgado ,  Chi-Ming Yang ,  Visar Nimani ,  Hui Ouyang ,  Sachin Bhatkar ,  Thomas Chang

发明人： Muralidhar Krishnaprasad ,  Mark Davis ,  Mark Ture ,  Cindy Hsin ,  Meeten Bhavsar ,  Hiroshi Koide ,  Joaquin Delgado ,  Chi-Ming Yang ,  Visar Nimani ,  Hui Ouyang ,  Sachin Bhatkar ,  Thomas Chang

IPC分类号： G06F21/31 ,  G06F21/62 ,  H04L29/06 ,  G06F17/30

CPC分类号： H04L63/08 ,  G06F17/30011 ,  G06F17/30321 ,  G06F17/30477 ,  G06F17/30554 ,  G06F17/30864 ,  G06F17/30867 ,  G06F21/31 ,  G06F21/6227 ,  H04L63/0815 ,  H04L63/083 ,  H04L63/102

摘要： A flexible and extensible architecture allows for secure searching across an enterprise. Such an architecture can provide a simple Internet-like search experience to users searching secure content inside (and outside) the enterprise. The architecture allows for the crawling and searching of a variety of sources across an enterprise, regardless of whether any of these sources conform to a conventional user role model. The architecture further allows for security attributes to be submitted at query time, for example, in order to provide real-time secure access to enterprise resources. The user query also can be transformed to provide for dynamic querying that provides for a more current result list than can be obtained for static queries.

摘要翻译： 灵活可扩展的架构允许跨企业进行安全搜索。 这样的架构可以为在企业内部（和外部）搜索安全内容的用户提供简单的类似Internet的搜索体验。 该架构允许在整个企业中爬行和搜索各种源，而不管这些源是否符合常规用户角色模型。 该体系结构进一步允许在查询时提交安全属性，例如为了提供对企业资源的实时安全访问。 用户查询也可以被转换以提供动态查询，其提供比静态查询可获得的更多当前结果列表。

公开(公告)号：US09111236B2

公开(公告)日：2015-08-18

申请号：US13443584

申请日：2012-04-10

申请人： Jeff Bonforte ,  Mark Davis

发明人： Jeff Bonforte ,  Mark Davis

IPC分类号： G06F17/30 ,  H04L29/08 ,  G06Q10/00 ,  G06Q10/06

CPC分类号： G06Q10/00 ,  G06Q10/06

摘要： A system and methodology for visually representing user activity associated with an information resource is described. User activities are associated with symbolic representations of those user activities. To visually convey selected aspects of the user activity, the activity is mapped to visual attributes that alter the appearance of the symbolic representation. The result is a dynamic and universal representation of user activities that aide online users to efficiently discern the relevancy and popularity of an information resource.

摘要翻译： 描述用于可视地表示与信息资源相关联的用户活动的系统和方法。 用户活动与这些用户活动的符号表示相关联。 为了可视地传达用户活动的选定方面，活动被映射到改变符号表示的外观的视觉属性。 结果是用户活动的动态和普遍表现，帮助在线用户有效地辨别信息资源的相关性和受欢迎程度。

公开(公告)号：US09069929B2

公开(公告)日：2015-06-30

申请号：US13527498

申请日：2012-06-19

申请人： David Borland ,  Arnold Thomas Schnell ,  Mark Davis

发明人： David Borland ,  Arnold Thomas Schnell ,  Mark Davis

IPC分类号： G06F1/32 ,  G06F15/78

CPC分类号： G06F15/7803 ,  G06F13/4068 ,  G06F13/4282 ,  Y02D10/12 ,  Y02D10/13 ,  Y02D10/14 ,  Y02D10/151

摘要： A node card includes a substrate having a connector that communicates a plurality of signals between the substrate and an outside entity. One or more nodes are connected to the substrate, and the one or more nodes receive power from one or more signals communicated over the connector. The one or more nodes also communicate with the outside entity using the one or more signals communicated over the connector.

摘要翻译： 节点卡包括具有在基板和外部实体之间传送多个信号的连接器的基板。 一个或多个节点连接到衬底，并且一个或多个节点从通过连接器传送的一个或多个信号接收电力。 一个或多个节点还使用通过连接器传送的一个或多个信号与外部实体进行通信。

公开(公告)号：US08531286B2

公开(公告)日：2013-09-10

申请号：US12204019

申请日：2008-09-04

申请人： Gary Friar ,  Mark Davis

发明人： Gary Friar ,  Mark Davis

IPC分类号： G08B29/00 ,  G08B1/00 ,  H04Q1/30

CPC分类号： G08B25/08

摘要： A security system includes at least one audio sensor and an alarm panel that transmits alarm report data through a communications network to at least one alarm receiver located at a central station remote from the premises that receives the alarm report data transmitted from the alarm panel through the communications network. A line card receives the alarm report data. An alarm receiver processor receives and processes regulated alarm report data in accordance with Underwriter Laboratories 1610 requirements. The line card is operable for receiving non-regulated alarm report data that is not regulated in accordance with Underwriter Laboratories 1610 requirements. The line card includes a secondary communications channel interfaced to a central station automation system and routes the regulated alarm report data to the central station automation system over the secondary communications channel and bypasses the alarm receiver processor.

摘要翻译： 安全系统包括至少一个音频传感器和报警面板，其通过通信网络将报警报告数据传送到位于远离场所的中心站处的至少一个报警接收机，其接收从报警面板传送的报警报告数据 通讯网络 线卡接收报警报告数据。 报警接收器处理器根据Underwriter Laboratories 1610要求接收和处理受监控的报警报告数据。 线卡可操作用于接收不符合Underwriter Laboratories 1610要求的非限制报警报告数据。 线路卡包括与中央站自动化系统相连接的辅助通信信道，并且通过辅助通信信道将调节的报警报告数据路由到中央站自动化系统，并绕过报警接收机处理器。

公开(公告)号：US08475781B2

公开(公告)日：2013-07-02

申请号：US13572243

申请日：2012-08-10

申请人： Jianjun Cheng ,  Mark Davis ,  Kay T. Khin

发明人： Jianjun Cheng ,  Mark Davis ,  Kay T. Khin

IPC分类号： A61K31/765 ,  C08G69/08 ,  C08G69/10 ,  C08L5/16 ,  C08L77/04 ,  A61K47/48 ,  C08G61/04 ,  C08G61/06

CPC分类号： C08G69/44 ,  A61K31/337 ,  A61K31/7048 ,  A61K47/48176 ,  A61K47/48192 ,  A61K47/482 ,  A61K47/48215 ,  A61K47/4823 ,  A61K47/48338 ,  A61K47/48969 ,  A61K47/58 ,  A61K47/59 ,  A61K47/60 ,  A61K47/61 ,  A61K47/6951 ,  B82Y5/00 ,  C08B30/00 ,  C08B31/00 ,  C08B37/0012 ,  C08F220/28 ,  C08F220/58 ,  C08F222/22 ,  C08F2220/282 ,  C08G81/02 ,  G06F19/00 ,  G06F19/3456 ,  G06Q50/22 ,  Y02A90/22 ,  Y02A90/26

摘要： The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.

公开(公告)号：US20130022040A1

公开(公告)日：2013-01-24

申请号：US13624731

申请日：2012-09-21

申请人： Mark Davis ,  David James Borland

发明人： Mark Davis ,  David James Borland

IPC分类号： H04L12/64

CPC分类号： H04L45/74 ,  G06F1/3234 ,  G06F3/0605 ,  G06F3/0631 ,  G06F3/067 ,  G06F9/5016 ,  G06F12/0284 ,  G06F13/00 ,  G06F13/24 ,  G06F13/40 ,  H04L45/00 ,  H04L45/60 ,  H04L45/7457 ,  H04L47/10 ,  H04L49/109 ,  H04L49/15 ,  H04L49/201 ,  H04L49/25 ,  H04L49/253 ,  H04L49/3009 ,  H04L49/351 ,  H04L49/356 ,  Y02B70/16 ,  Y02B70/30 ,  Y02B70/32 ,  Y02D10/14 ,  Y02D10/151 ,  Y02D30/32

摘要： A system and method are provided that support a routing using a tree-like or graph topology that supports multiple links per node, where each link is designated as an Up, Down, or Lateral link, or both, within the topology. The system may use a segmented MAC architecture which may have a method of re-purposing MAC IP addresses for inside MACs and outside MACs, and leveraging what would normally be the physical signaling for the MAC to feed into the switch.

摘要翻译： 提供了一种系统和方法，其支持使用支持多个链路的树状或图形拓扑的路由，每个节点在拓扑中指定每条链路为Up，Down或Lateral链路，或两者。 该系统可以使用分段MAC架构，其可以具有为内部MAC和外部MAC重新使用MAC IP地址的方法，并且利用通常将MAC的物理信令馈送到交换机中。

公开(公告)号：US20110245201A1

公开(公告)日：2011-10-06

申请号：US13047766

申请日：2011-03-14

申请人： John Ryan ,  Thomas Schluep ,  Yun Yen ,  James C. Oliver ,  Mark Davis

发明人： John Ryan ,  Thomas Schluep ,  Yun Yen ,  James C. Oliver ,  Mark Davis

IPC分类号： A61K31/724 ,  A61K31/475 ,  A61P35/00

CPC分类号： C07D491/22

摘要： Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101.

摘要翻译： 提供了涉及包括CDP-拓扑异构酶抑制剂，例如CDP-喜树碱或喜树碱衍生物缀合物例如CRLX101的组合物的方法。