公开(公告)号：US09877781B2

公开(公告)日：2018-01-30

申请号：US13885776

申请日：2011-11-18

申请人： Martin M. Grasse ,  Richard E. Stehr ,  Israel A. Byrd ,  Lynn E. Gilmour ,  D. Curtis Deno ,  Troy T. Tegg ,  James V. Kauphusman ,  Saurav Paul ,  Jeffrey A. Schweitzer

发明人： Martin M. Grasse ,  Richard E. Stehr ,  Israel A. Byrd ,  Lynn E. Gilmour ,  D. Curtis Deno ,  Troy T. Tegg ,  James V. Kauphusman ,  Saurav Paul ,  Jeffrey A. Schweitzer

IPC分类号： A61N1/00 ,  A61B5/04 ,  A61B18/16 ,  A61B5/042 ,  A61B18/14 ,  A61B18/00 ,  A61M25/01 ,  A61M25/06

CPC分类号： A61B18/16 ,  A61B5/042 ,  A61B18/1492 ,  A61B2018/00357 ,  A61B2018/00613 ,  A61B2018/00791 ,  A61B2018/1435 ,  A61B2018/162 ,  A61M25/0147 ,  A61M2025/0681

摘要： An electrode catheter device with indifferent electrode for direct current tissue therapies is disclosed. An example of the catheter device has a flexible tubing with at least one ablation electrode. The catheter device also may also be used with a sheath for introducing the flexible tubing inside a patient's body. An indifferent electrode on the sheath can provide a ground for a direct current (DC) pulse to deliver electrical energy and create an electrical field adjacent a tissue. Various other embodiments are also disclosed.

公开(公告)号：US20130338467A1

公开(公告)日：2013-12-19

申请号：US13885776

申请日：2011-11-18

申请人： Martin M. Grasse ,  Richard E. Stehr ,  Israel A. Byrd ,  Lynn E. Clark ,  D. Curtis Deno ,  Troy T. Tegg ,  James V. Kauphusman ,  Saurav Paul ,  Jeffrey A. Schweitzer

发明人： Martin M. Grasse ,  Richard E. Stehr ,  Israel A. Byrd ,  Lynn E. Clark ,  D. Curtis Deno ,  Troy T. Tegg ,  James V. Kauphusman ,  Saurav Paul ,  Jeffrey A. Schweitzer

IPC分类号： A61B18/16

CPC分类号： A61B18/16 ,  A61B5/042 ,  A61B18/1492 ,  A61B2018/00357 ,  A61B2018/00613 ,  A61B2018/00791 ,  A61B2018/1435 ,  A61B2018/162 ,  A61M25/0147 ,  A61M2025/0681

摘要： An electrode catheter device with indifferent electrode for direct current tissue therapies is disclosed. An example of the catheter device has a flexible tubing with at least one ablation electrode. The catheter device also may also be used with a sheath for introducing the flexible tubing inside a patient's body. An indifferent electrode on the sheath can provide a ground for a direct current (DC) pulse to deliver electrical energy and create an electrical field adjacent a tissue. Various other embodiments are also disclosed.

摘要翻译： 公开了一种具有用于直流组织治疗的无电极的电极导管装置。 导管装置的示例具有带有至少一个消融电极的柔性管。 导管装置还可以与护套一起使用以将柔性管引入患者体内。 护套上的无电极可以为直流（DC）脉冲提供接地，以传递电能并在组织附近产生电场。 还公开了各种其它实施例。

公开(公告)号：US20120165664A1

公开(公告)日：2012-06-28

申请号：US12979170

申请日：2010-12-27

申请人： Anthony D. Hill ,  D. Curtis Deno ,  Martin M. Grasse ,  Robert D. Aiken ,  Daniel A. Feeney

发明人： Anthony D. Hill ,  D. Curtis Deno ,  Martin M. Grasse ,  Robert D. Aiken ,  Daniel A. Feeney

IPC分类号： A61B8/14

CPC分类号： A61B8/463 ,  A61B8/0883 ,  A61B8/12 ,  A61B8/14 ,  A61B8/4263 ,  A61B8/4488 ,  A61B8/483 ,  A61B8/543 ,  G06T9/20 ,  G06T19/20 ,  G06T2219/2012 ,  G16H50/50

摘要： A method of refining an anatomical model includes acquiring a two-dimensional echocardiogram that has a variable intensity, relating the two-dimensional echocardiogram to a plurality of mapping points that exist in three-dimensional space, and determining a confidence value for each of two or more mapping points that corresponds to an intensity at a point on the two-dimensional echocardiogram.

摘要翻译： 精炼解剖学模型的方法包括获取具有可变强度的二维超声心动图，将二维超声心动图与存在于三维空间中的多个映射点相关联，并且确定两个或 更多的映射点对应于二维超声心动图上一点的强度。

公开(公告)号：US20120172724A1

公开(公告)日：2012-07-05

申请号：US12983013

申请日：2010-12-31

申请人： Anthony D. Hill ,  D. Curtis Deno ,  Hua Zhong ,  Martin M. Grasse

发明人： Anthony D. Hill ,  D. Curtis Deno ,  Hua Zhong ,  Martin M. Grasse

IPC分类号： A61B8/14

CPC分类号： A61B8/12 ,  A61B8/0841 ,  A61B8/0883 ,  A61B8/4245 ,  A61B8/461 ,  A61B8/463 ,  A61B8/5246 ,  G06T19/00 ,  G06T2210/41

摘要： An intracardiac imaging system configured to display electrode visualization elements within an intracardiac echocardiography image where the electrode visualization elements represent intracardiac electrodes in close proximity to the plane of the image. The system further allows cross sections of tissue structures embodied in intracardiac echocardiography images to be modeled within a visualization, navigation, or mapping system when automatically segmented to generate shell elements for modifying the modeled tissue structures.

摘要翻译： 心室内成像系统被配置为在心内超声心动图图像中显示电极可视化元件，其中电极可视化元件代表紧邻图像平面的心脏内电极。 当自动分段以产生用于修改建模的组织结构的壳单元时，系统进一步允许体现在心内超声心动图图像中的组织结构的横截面被建模在可视化，导航或映射系统内。

公开(公告)号：US10524765B2

公开(公告)日：2020-01-07

申请号：US12979170

申请日：2010-12-27

申请人： Anthony D. Hill ,  D. Curtis Deno ,  Martin M. Grasse ,  Robert D. Aiken ,  Daniel A. Feeney

发明人： Anthony D. Hill ,  D. Curtis Deno ,  Martin M. Grasse ,  Robert D. Aiken ,  Daniel A. Feeney

IPC分类号： A61B8/00 ,  G06T9/20 ,  A61B8/08 ,  A61B8/12 ,  G06T19/20 ,  A61B8/14 ,  G16H50/50

摘要： A method of refining an anatomical model includes acquiring a two-dimensional echocardiogram that has a variable intensity, relating the two-dimensional echocardiogram to a plurality of mapping points that exist in three-dimensional space, and determining a confidence value for each of two or more mapping points that corresponds to an intensity at a point on the two-dimensional echocardiogram.

公开(公告)号：US09125573B2

公开(公告)日：2015-09-08

申请号：US13339547

申请日：2011-12-29

申请人： Lev A. Koyrakh ,  Daniel J. Potter ,  Jeffrey A. Schweitzer ,  D. Curtis Deno ,  Anthony D. Hill ,  Dale Eric Just

发明人： Lev A. Koyrakh ,  Daniel J. Potter ,  Jeffrey A. Schweitzer ,  D. Curtis Deno ,  Anthony D. Hill ,  Dale Eric Just

IPC分类号： A61B5/04 ,  A61M25/06 ,  A61B5/053 ,  A61B5/145 ,  A61B5/024 ,  A61M25/00

CPC分类号： A61B5/04 ,  A61B5/02444 ,  A61B5/0538 ,  A61B5/14503 ,  A61B2560/06 ,  A61M25/005 ,  A61M25/0662

摘要： An introducer sheath for a medical device is provided. The sheath includes a deformable, elongate body disposed about a longitudinal axis. The body has proximal and distal ends and defines a lumen extending between the proximal and distal ends and configured to allow passage of the medical device therethrough. The body is configured to allow an electric current to pass radially between a space outside of the body and the lumen such that the position of the medical device within a patient can be monitored and electrogram readings from body tissues can be measured while the device is in the sheath. In some embodiments of the invention, the body may include a one or more apertures extending from the radially outer surface of the body to the lumen or a portion of the body may be made from a conductive and/or fluid permeable material.

摘要翻译： 提供了一种用于医疗装置的引导器护套。 护套包括围绕纵向轴线设置的可变形的细长体。 主体具有近端和远端并且限定在近端和远端之间延伸的构造成允许医疗装置通过的内腔。 身体构造成允许电流在身体外部的空间和内腔之间径向通过，使得可以监测患者体内的医疗装置的位置，并且可以在装置处于状态时测量来自身体组织的电描记图读数 护套。 在本发明的一些实施例中，主体可以包括从主体的径向外表面延伸到内腔的一个或多个孔，或者主体的一部分可以由导电和/或流体可渗透的材料制成。

公开(公告)号：US20140128722A1

公开(公告)日：2014-05-08

申请号：US14123698

申请日：2012-04-18

申请人： Jeffrey A. Schweitzer ,  D. Curtis Deno ,  Timothy G. Curran ,  Larry J. Hull

发明人： Jeffrey A. Schweitzer ,  D. Curtis Deno ,  Timothy G. Curran ,  Larry J. Hull

IPC分类号： A61B5/06 ,  A61B5/042 ,  G01R33/567 ,  A61B5/00

CPC分类号： A61B5/062 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/055 ,  A61B5/063 ,  A61B5/7203 ,  A61B5/7217 ,  A61B5/7264 ,  A61B18/1492 ,  A61B34/20 ,  A61B2090/374 ,  G01R33/5673

摘要： A system and method for tracking catheter electrode locations with the body of a patient during an MRI scan sequence includes mitigation logic configured to identify one or more impedance measurements that were taken during potentially noise-inducing conditions (i.e., magnet gradients, RF pulses), and were thus subject to corruption by noise. The mitigation logic is configured to replace the potentially corrupt impedance measurements with previously-obtained impedance measurements taken from an immediately preceding acquisition cycle (e.g., from a previous time-slice).

摘要翻译： 用于在MRI扫描序列期间跟踪患者身体的导管电极位置的系统和方法包括被配置为识别在潜在的引起噪声的条件（即磁梯度，RF脉冲）期间所采取的一个或多个阻抗测量的缓解逻辑， 因此受到噪音的腐败。 缓解逻辑被配置为用先前获得的阻抗测量值取代潜在的损坏的阻抗测量值，该阻抗测量值取自紧接在前的采集周期（例如，从先前的时间片）。

公开(公告)号：US20130172712A1

公开(公告)日：2013-07-04

申请号：US13339547

申请日：2011-12-29

申请人： Lev A. Koyrakh ,  Daniel J. Potter ,  Jeffrey A. Schweitzer ,  D. Curtis Deno ,  Anthony D. Hill ,  Dale E. Just

发明人： Lev A. Koyrakh ,  Daniel J. Potter ,  Jeffrey A. Schweitzer ,  D. Curtis Deno ,  Anthony D. Hill ,  Dale E. Just

IPC分类号： A61B5/04

CPC分类号： A61B5/04 ,  A61B5/02444 ,  A61B5/0538 ,  A61B5/14503 ,  A61B2560/06 ,  A61M25/005 ,  A61M25/0662

摘要： An introducer sheath for a medical device is provided. The sheath includes a deformable, elongate body disposed about a longitudinal axis. The body has proximal and distal ends and defines a lumen extending between the proximal and distal ends and configured to allow passage of the medical device therethrough. The body is configured to allow an electric current to pass radially between a space outside of the body and the lumen such that the position of the medical device within a patient can be monitored and electrogram readings from body tissues can be measured while the device is in the sheath. In some embodiments of the invention, the body may include a one or more apertures extending from the radially outer surface of the body to the lumen or a portion of the body may be made from a conductive and/or fluid permeable material.

摘要翻译： 提供了一种用于医疗装置的引导器护套。 护套包括围绕纵向轴线设置的可变形的细长体。 主体具有近端和远端并且限定在近端和远端之间延伸的构造成允许医疗装置通过的内腔。 身体构造成允许电流在身体外部的空间和内腔之间径向通过，使得可以监测患者体内的医疗装置的位置，并且可以在装置处于状态时测量来自身体组织的电描记图读数 护套。 在本发明的一些实施例中，主体可以包括从主体的径向外表面延伸到内腔的一个或多个孔，或者主体的一部分可以由导电和/或流体可渗透材料制成。

公开(公告)号：US09833168B2

公开(公告)日：2017-12-05

申请号：US14123698

申请日：2012-04-18

申请人： Jeffrey A. Schweitzer ,  D. Curtis Deno ,  Timothy G. Curran ,  Larry J. Hull

发明人： Jeffrey A. Schweitzer ,  D. Curtis Deno ,  Timothy G. Curran ,  Larry J. Hull

IPC分类号： A61B5/06 ,  A61B5/00 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/055 ,  G01R33/567 ,  A61B34/20 ,  A61B18/14 ,  A61B90/00

CPC分类号： A61B5/062 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/055 ,  A61B5/063 ,  A61B5/7203 ,  A61B5/7217 ,  A61B5/7264 ,  A61B18/1492 ,  A61B34/20 ,  A61B2090/374 ,  G01R33/5673

摘要： A system and method for tracking catheter electrode locations with the body of a patient during an MRI scan sequence includes mitigation logic configured to identify one or more impedance measurements that were taken during potentially noise-inducing conditions (i.e., magnet gradients, RF pulses), and were thus subject to corruption by noise. The mitigation logic is configured to replace the potentially corrupt impedance measurements with previously-obtained impedance measurements taken from an immediately preceding acquisition cycle (e.g., from a previous time-slice).

公开(公告)号：US20100168557A1

公开(公告)日：2010-07-01

申请号：US12346592

申请日：2008-12-30

申请人： D. Curtis Deno ,  Jeffrey A. Schweitzer ,  John A. Hauck

发明人： D. Curtis Deno ,  Jeffrey A. Schweitzer ,  John A. Hauck

IPC分类号： A61B18/18 ,  A61B5/05 ,  A61B18/14 ,  A61B5/053

CPC分类号： A61B5/0422 ,  A61B5/053 ,  A61B5/0538 ,  A61B18/14 ,  A61B2018/00755 ,  A61B2018/00839 ,  A61B2018/00875 ,  A61B2034/2051 ,  A61B2562/046

摘要： The invention is directed to a multi-electrode ablation sensing catheter and system suitable for medical procedures such as cardiac ablation. In one embodiment of the invention, a catheter is provided having an elongated catheter shaft and a catheter tip having two or more closely spaced electrodes mounted on the catheter tip, where the electrodes are coupled to a plurality of electronic circuitries and are used for electrogram sensing, impedance sensing, and location sensing and orientation. In another embodiment of the invention, a catheter system is provided having a catheter with an elongated catheter shaft and a catheter tip with two or more closely spaced electrodes mounted on the catheter tip, and an RF generator circuitry, an electrogram sensing circuitry, an impedance sensing circuitry, and a location sensing and orientation circuitry.

摘要翻译： 本发明涉及一种适用于诸如心脏消融的医疗程序的多电极消融感测导管和系统。 在本发明的一个实施例中，提供导管，其具有细长的导管轴和具有安装在导管尖端上的两个或更多个紧密间隔的电极的导管末端，其中电极耦合到多个电子电路并且用于电描记图感测 ，阻抗感测和位置感测和定位。 在本发明的另一个实施例中，提供导管系统，其具有带有细长导管轴的导管，以及安装在导管尖端上的具有两个或更多个紧密间隔的电极的导管末端，以及RF发生器电路，电描记图检测电路，阻抗 感测电路，以及位置感测和取向电路。