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    Multi-well plate with alignment grooves for encoded microparticles
    1.
    发明申请
    Multi-well plate with alignment grooves for encoded microparticles 审中-公开
    具有用于编码微粒的对准槽的多孔板

    公开(公告)号：US20060160208A1

    公开(公告)日：2006-07-20

    申请号：US11063665

    申请日：2005-02-22

    申请人： Martin Putnam ,  James Sirkis ,  John Moon ,  Tuo Li ,  Joseph Traynor ,  Robert Brucato

    发明人： Martin Putnam ,  James Sirkis ,  John Moon ,  Tuo Li ,  Joseph Traynor ,  Robert Brucato

    IPC分类号： C12M1/34 ,  G06K7/00 ,  G01N33/551 ,  C12M3/00

    CPC分类号： G01N33/54313 ,  G01N33/54393

    摘要： A method and apparatus are provided for aligning optical elements or microbeads, wherein each microbead has an elongated body with a code embedded therein along a longitudinal axis thereof to be read by a code reading device. The microbeads are aligned with a positioning device so the longitudinal axis of the microbeads is positioned in a fixed orientation relative to the code reading device. The microbeads are typically cylindrically shaped glass beads between 25 and 250 microns (μm) in diameter and between 100 and 500 μm long, and have a holographic code embedded in the central region of the bead, which is used to identify it from the rest of the beads in a batch of beads with many different chemical probes. A cross reference is used to determine which probe is attached to which bead, thus allowing the researcher to correlate the chemical content on each bead with the measured fluorescence signal. Because the code consists of a diffraction grating typically disposed along an axis, there is a particular alignment required between the incident readout laser beam and the readout detector in two of the three rotational axes. The third axis, rotation about the center axis of the cylinder, is azimuthally symmetric and therefore does not require alignment.

    摘要翻译： 提供了一种用于对准光学元件或微珠的方法和装置，其中每个微珠具有细长体，其沿着其纵向轴线嵌入其中的代码，以被代码读取装置读取。 微珠与定位装置对准，使得微珠的纵向轴线相对于代码读取装置定位成固定的取向。 微珠通常为直径为25至250微米（母体）和长度为100至500毫米的圆柱形玻璃珠，并且具有嵌入珠的中心区域中的全息代码，其用于从其余部分识别它 珠子中有一批具有许多不同化学探针的珠粒。 交叉参考用于确定哪个探针连接到哪个珠，从而允许研究者将每个珠上的化学成分与测量的荧光信号相关联。 由于代码由通常沿轴线设置的衍射光栅组成，所以在三个旋转轴中的两个中存在入射读出激光束和读出检测器之间所需的特定对准。 第三轴，围绕气缸的中心轴的旋转是方位对称的，因此不需要对准。

    Fabry-perot sensing element based on a large-diameter optical waveguide
    2.
    发明申请
    Fabry-perot sensing element based on a large-diameter optical waveguide 有权
    基于大直径光波导的法布里 - 珀罗感应元件

    公开(公告)号：US20050213870A1

    公开(公告)日：2005-09-29

    申请号：US11136144

    申请日：2005-05-24

    申请人： Alan Kersey ,  Martin Putnam ,  Mark Fernald ,  Robert Brucato ,  James Sirkis

    发明人： Alan Kersey ,  Martin Putnam ,  Mark Fernald ,  Robert Brucato ,  James Sirkis

    IPC分类号： G01L1/24 ,  G02B6/34 ,  G02B6/26

    CPC分类号： G02B6/29317 ,  G01L1/242 ,  G02B6/29334 ,  G02B6/29358 ,  G02B6/29359 ,  G02B6/29389

    摘要： An optical sensing device including a force-applying assembly for providing a force and a Fabry-Perot (FP) element including a large-diameter waveguide having a core and having a cavity in line with the core, the cavity having reflective surfaces and having an optical path length related to the distance between the reflective surfaces, the FP element being coupled to the force so that the optical path length changes according to the force, the FP element for providing an output optical signal containing information about a parameter that relates to the force. Sometimes the large-diameter waveguide is formed by collapsing a glass tube, having a bore and having an outer diameter of about one millimeter, onto a pair of optical fibers arranged in tandem in the bore and separated by a predetermined distance, and respective end faces of the optical fibers form the cavity and are coated with a wholly or partially reflective material.

    摘要翻译： 一种光学传感装置，包括用于提供力的力施加组件和包括具有芯的大直径波导的法布里 - 珀罗（FP）元件，并且具有与所述芯一致的空腔，所述腔具有反射表面并且具有 光路长度与反射表面之间的距离相关联，FP元件被耦合到力，使得光路长度根据力而变化，FP元件用于提供包含关于参数的参数的信息的输出光信号 力。 有时，大直径波导是通过将具有孔径并且具有约1毫米的外径的玻璃管塌陷在一起在孔中并排布置预定距离的一对光纤上而形成的，并且相应的端面 的光纤形成空腔并涂覆有全部或部分反射材料。

    Optical channel monitor
    3.
    发明授权
    Optical channel monitor 有权
    光通道监视器

    公开(公告)号：US07463828B2

    公开(公告)日：2008-12-09

    申请号：US10159370

    申请日：2002-05-31

    申请人： John Moon ,  Ralph Jones ,  Charles Winston ,  James Sirkis ,  David Fournier ,  Joseph Pinto ,  Robert Brucato ,  James Dunphy ,  Christopher Chestnut

    发明人： John Moon ,  Ralph Jones ,  Charles Winston ,  James Sirkis ,  David Fournier ,  Joseph Pinto ,  Robert Brucato ,  James Dunphy ,  Christopher Chestnut

    IPC分类号： G02B6/26 ,  H01S3/08 ,  G01J3/18

    CPC分类号： G01J3/28 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0256 ,  G01J3/0291 ,  G01J3/06 ,  G01J3/32 ,  G01J3/36 ,  G01J2003/064 ,  G01J2003/1819 ,  G02B6/2706 ,  G02B6/2793 ,  G02B6/2931 ,  G02B6/29313 ,  G02B6/29314 ,  G02B6/29385 ,  G02B6/29398 ,  G02B6/3512 ,  G02B6/359 ,  G02B6/4215 ,  G02B6/4246 ,  H04B10/077 ,  H04B10/07955 ,  H04Q2011/0026 ,  H04Q2011/0049 ,  H04Q2011/0083

    摘要： An optical channel monitor is provided that sequentially or selectively filters an optical channel(s) 11 of light from a (WDM) optical input signal 12 and senses predetermined parameters of the each filtered optical signal (e.g., channel power, channel presence, signal-noise-ratio). The OCM 10 is a free-space optical device that includes a collimator assembly 15, a diffraction grating 20 and a mirror 22. A launch pigtail emits into free space the input signal through the collimator assembly 15 and onto the diffraction grating 20, which separates spatially each of the optical channels 11 of the collimated light, and reflects the separated channels of light onto the mirror 22. A λ/4 plate 26 is disposed between the mirror 22 and the diffraction grating 20. The mirror reflects the separated light back through the λ/4 plate 26 to the diffraction grating 20, which reflects the channels of light back through the collimating lens 18. The lens 18 focuses each separated channel of light (λ1-λN) at a different focal point in space. One of the optical channels 11 is focused onto a receive pigtail 28, which then propagates to a photodetector 30. A pivoting mechanism 34 pivots the diffraction grating 20 or mirror 22 about a pivot point 36 to sequentially or selectively focus each optical channel 11 to the receive pigtail 28. A position sensor 42 detects the displacement of the diffraction grating 24 or mirror.

    摘要翻译： 提供了一种光通道监视器，其顺序地或选择性地对来自（WDM）光输入信号12的光的通道11进行滤波，并且感测每个滤波的光信号的预定参数（例如，信道功率，信道存在， 噪声比）。 OCM 10是包括准直器组件15，衍射光栅20和反射镜22的自由空间光学装置。发射尾纤通过准直器组件15和衍射光栅20将衍射光栅20发射到自由空间中，输入信号分离 准直光的每个光通道11，并将分离的光反射到反射镜22上.λ/ 4板26设置在反射镜22和衍射光栅20之间。反射镜将分离的光反射回 λ/ 4板26到衍射光栅20，其反射通过准直透镜18的光通道。透镜18将每个分离的光（λ1-λN）通道在空间中的不同焦点处聚焦。 光通道11中的一个被聚焦到接收引线28上，接收引线28然后传播到光电检测器30.枢转机构34围绕枢转点36枢转衍射光栅20或反射镜22，以顺序地或选择性地将每个光通道11聚焦到 接收尾纤28.位置传感器42检测衍射光栅24或反射镜的位移。