公开(公告)号：US5518570A

公开(公告)日：1996-05-21

申请号：US278812

申请日：1994-07-22

申请人： Masazumi Takagi ,  Toshio Onuma ,  Tatsuya Watanabe ,  Toshiaki Enami ,  Kazuo Tanihira ,  Hirotaka Sawada ,  Kuni Yoshinuma ,  Hiroaki Komatsuda

发明人： Masazumi Takagi ,  Toshio Onuma ,  Tatsuya Watanabe ,  Toshiaki Enami ,  Kazuo Tanihira ,  Hirotaka Sawada ,  Kuni Yoshinuma ,  Hiroaki Komatsuda

IPC分类号： B65H39/14 ,  H01B7/08 ,  B32B5/02 ,  B32B31/10

CPC分类号： B65H39/14 ,  H01B7/0838 ,  Y10S29/90 ,  Y10T156/1052 ,  Y10T156/1074 ,  Y10T156/1097 ,  Y10T156/1098 ,  Y10T156/125 ,  Y10T156/133 ,  Y10T156/1734 ,  Y10T156/1741 ,  Y10T156/1773 ,  Y10T83/0348 ,  Y10T83/4838 ,  Y10T83/8805

摘要： There is disclosed an apparatus and method for bonding a sheet material to an elongated base material, in which the sheet material is transferred by a transferring device towards the base material, and the sheet material is bonded by a bonding device to the base material. A static electricity generating device is attached to the bonding device for generating static electricity on the sheet material to cause the sheet material to adhere to the bonding device, so that the sheet material is prevented from falling from the bonding device prior to the bonding step. Furthermore, an apparatus and method for manufacturing a flexible flat cable, applying the above bonding apparatus and method is also disclosed. In this apparatus and method, a pair of insulating tape sheets are transferred towards electric conductors. Prior to the bonding step at a pair of hot rolls, the insulating tape sheets adhered to the hot rolls are cut into discrete tapes, and the discrete tapes are prevented from falling from the hot rolls by the static electricity generated thereon. With this apparatus and method, not only a substantial reduction in the cost of materials but also an enhanced productivity of the flexible flat cables can be ensured, and the problem of noise generated by press machines can be avoided.

公开(公告)号：US5387298A

公开(公告)日：1995-02-07

申请号：US50593

申请日：1993-04-22

申请人： Masazumi Takagi ,  Toshio Onuma ,  Tatsuya Watanabe ,  Toshiaki Enami ,  Kazuo Tanihira ,  Hirotaka Sawada ,  Kuni Yoshinuma ,  Hiroaki Komatsuda

发明人： Masazumi Takagi ,  Toshio Onuma ,  Tatsuya Watanabe ,  Toshiaki Enami ,  Kazuo Tanihira ,  Hirotaka Sawada ,  Kuni Yoshinuma ,  Hiroaki Komatsuda

IPC分类号： B65H39/14 ,  H01B7/08 ,  H01B13/18 ,  H02N13/00

CPC分类号： B65H39/14 ,  H01B7/0838 ,  Y10S29/90 ,  Y10T156/1052 ,  Y10T156/1074 ,  Y10T156/1097 ,  Y10T156/1098 ,  Y10T156/125 ,  Y10T156/133 ,  Y10T156/1734 ,  Y10T156/1741 ,  Y10T156/1773 ,  Y10T83/0348 ,  Y10T83/4838 ,  Y10T83/8805

摘要： There is disclosed an apparatus and method for bonding a sheet material to an elongated base material, in which the sheet material is transferred by a transferring device towards the base material, and the sheet material is bonded by a bonding device to the base material. A static electricity generating device is attached to the bonding device for generating static electricity on the sheet material to cause the sheet material to adhere to the bonding device, so that the sheet material is prevented from falling from the bonding device prior to the bonding step. Furthermore, an apparatus and method for manufacturing a flexible flat cable, applying the above bonding apparatus and method is also disclosed. In this apparatus and method, a pair of insulating tape sheets are transferred towards electric conductors. Prior to the bonding step at a pair of hot rolls, the insulating tape sheets adhered to the hot rolls are cut into discrete tapes, and the discrete tapes are prevented from falling from the hot rolls by the static electricity generated thereon. With this apparatus and method, not only a substantial reduction in the cost of materials but also an enhanced productivity of the flexible flat cables can be ensured, and the problem of noise generated by press machines can be avoided.

摘要翻译： 公开了一种用于将片材接合到细长基材的装置和方法，其中片材通过转印装置转移到基底材料，并且片材通过粘结装置粘合到基底材料上。 静电发生装置安装在用于在片材上产生静电的接合装置，以使片材粘附到接合装置上，从而防止片材在接合步骤之前从接合装置落下。 此外，还公开了应用上述接合装置和方法的柔性扁平电缆的制造装置和方法。 在这种装置和方法中，一对绝缘带片被传送到电导体。 在一对热辊之间的接合步骤之前，粘附到热辊上的绝缘带片被切割成离散带，并且通过其上产生的静电防止离散带从热辊落下。 利用该装置和方法，不仅可以确保材料成本的显着降低，而且可以确保柔性扁平电缆的提高的生产率，并且可以避免冲压机产生的噪音的问题。

公开(公告)号：US20120283120A1

公开(公告)日：2012-11-08

申请号：US13498840

申请日：2010-09-28

申请人： Tatsuya Watanabe ,  Kazuhide Nakayama ,  Daisuke Nakata ,  Masami Kusaka

发明人： Tatsuya Watanabe ,  Kazuhide Nakayama ,  Daisuke Nakata ,  Masami Kusaka

IPC分类号： C07K14/705 ,  C40B30/04 ,  C12N5/10 ,  C12N15/113 ,  C12Q1/02 ,  C07H21/04 ,  C12Q1/68 ,  C12N15/12

CPC分类号： C07K14/721 ,  C07D227/087 ,  C12N15/1138 ,  C12N2310/14 ,  G01N33/743 ,  G01N2333/723 ,  G01N2500/10 ,  C12N2310/531

摘要： The present invention provides a novel variant androgen receptor (ARaiv) lacking ligand binding domain, a nucleic acid encoding the same and use thereof. That is, the present invention provides a method of screening for a substance for the prophylaxis or treatment of cancer, which includes contacting an ARaiv protein or ARaiv-producing cell with a test compound, measuring the activity of ARaiv (e.g., transcription regulating action of androgen responsive gene) or expression level thereof, and selecting a compound that suppresses the activity or expression level.

摘要翻译： 本发明提供了缺乏配体结合结构域的新型变体雄激素受体（ARaiv），编码其的核酸及其用途。 也就是说，本发明提供了筛选用于预防或治疗癌症的物质的方法，其包括使ARaiv蛋白或产生ARaiv的细胞与测试化合物接触，测量ARaiv的活性（例如，转录调节作用 雄激素应答基因）或其表达水平，并选择抑制活性或表达水平的化合物。

公开(公告)号：US20100141116A1

公开(公告)日：2010-06-10

申请号：US12630410

申请日：2009-12-03

申请人： Yu Nomura ,  Tatsuya Watanabe ,  Hiroyuki Kiso

发明人： Yu Nomura ,  Tatsuya Watanabe ,  Hiroyuki Kiso

IPC分类号： H01J1/70 ,  F21V13/08 ,  B29D11/00

CPC分类号： B29D11/00634 ,  H01L27/322 ,  H01L51/5271

摘要： A color filter preventing the occurrence of cross-talk between colors while improving light extraction efficiency, a method of manufacturing the color filter, and a light-emitting device are provided. The color filter includes: a plurality of color filter layers for a plurality of colors arranged on a substrate, a plurality of projections arranged in contact with the color filter layers, the projections of which parts on a side closer to the color filter layers are connected to one another; and a reflecting mirror film formed so as to be laid over a side surface of each of the plurality of projections.

摘要翻译： 提供一种防止颜色之间发生串扰的同时提高光提取效率的滤色器，制造滤色器的方法和发光器件。 滤色器包括：布置在基板上的多个颜色的多个滤色器层，与滤色器层接触地布置的多个突起，其上靠近滤色器层的一侧的部分被连接 彼此; 以及反射镜膜，其被形成为布置在所述多个突起中的每一个的侧表面上。

公开(公告)号：US20080287008A1

公开(公告)日：2008-11-20

申请号：US12152206

申请日：2008-05-13

申请人： Tatsuya Watanabe ,  Masahiko Imoto ,  Yoshinari Goshima

发明人： Tatsuya Watanabe ,  Masahiko Imoto ,  Yoshinari Goshima

IPC分类号： H01R13/66 ,  B29C70/72

CPC分类号： G01P1/023 ,  B29C33/123 ,  G01P15/125 ,  H01L21/565 ,  H01L2924/0002 ,  H01R43/24 ,  H05K5/0034 ,  H05K5/0078 ,  H05K5/065 ,  H01L2924/00

摘要： An electronic device includes an electronic circuit section, a case, and a connector housing. The electronic circuit section includes a connector terminal. The case seals the electronic circuit section in such a manner that the connector terminal protrudes to an outside of the case. The connector housing is integrated with the case and has an approximately cylindrical shape to surround an outer circumference of the connector terminal. The case and the connector housing are made of resin with a molding tool by filling resin into a case cavity and a connector-housing cavity of the molding tool in a state where the electronic circuit section is held by a holding portion of the molding tool.

摘要翻译： 电子设备包括电子电路部分，壳体和连接器壳体。 电子电路部分包括连接器端子。 壳体以使得连接器端子突出到壳体的外部的方式密封电子电路部分。 连接器壳体与壳体一体化并且具有围绕连接器端子的外圆周的大致圆柱形形状。 壳体和连接器壳体由具有模制工具的树脂制成，其通过在模制工具的保持部分保持电子电路部分的状态下将树脂填充到模腔中的壳体空腔和连接器壳体腔中。

公开(公告)号：US20080009506A1

公开(公告)日：2008-01-10

申请号：US11662948

申请日：2005-09-16

申请人： Mari Kusama ,  Tatsuya Watanabe ,  Toshihiro Hosaka ,  Yuko Kubota

发明人： Mari Kusama ,  Tatsuya Watanabe ,  Toshihiro Hosaka ,  Yuko Kubota

IPC分类号： A61K31/4178 ,  A61K31/415 ,  A61K31/4155 ,  A61K31/42 ,  A61K31/44 ,  A61K31/47 ,  A61K31/506 ,  A61P13/00 ,  C07D215/12 ,  C07D403/14 ,  C07D403/04 ,  C07D401/04 ,  C07D277/30 ,  C07D263/08 ,  C07D235/02 ,  C07D233/60 ,  C07D233/56 ,  C07D233/00 ,  C07D513/04 ,  C07D413/04 ,  A61P9/00 ,  A61P11/06 ,  A61K31/497 ,  A61K31/4439 ,  A61K31/425 ,  A61K31/4184 ,  A61K31/4168

CPC分类号： C07D233/64 ,  C07D401/04 ,  C07D403/10 ,  C07D409/04 ,  C07D487/04

摘要： An imidazole compound of the formula: wherein Ring A is benzene or a heterocyclic ring; G is alkylthio, alkylsulfonyl, optionally substituted phenyl, or optionally substituted heterocyclic ring group, etc.; Ring C is imidazole; R1 is carbamoyl, etc.; R2 is cyano, nitro, hydroxyl, an alkoxy, a halogen, carboxy, an alkoxycarbonyl, carbamoyl, amino, an alkyl, etc.; m is 0 to 2; and R4 is hydrogen, an alkyl, etc., or a pharmaceutically acceptable salt thereof, is a large conductance calcium-activated K channel opener useful for treatment of pollakiuria, urinary incontinence, etc.

摘要翻译： 下式的咪唑化合物：其中环A是苯或杂环; G是烷硫基，烷基磺酰基，任选取代的苯基或任选取代的杂环基团等; 环C是咪唑; R 1是氨基甲酰基等; R 2是氰基，硝基，羟基，烷氧基，卤素，羧基，烷氧基羰基，氨基甲酰基，氨基，烷基等; m为0〜2; R 4是氢，烷基等或其药学上可接受的盐，是用于治疗尿频，尿失禁等的大电导钙激活K通道开放剂。

公开(公告)号：US20060094724A1

公开(公告)日：2006-05-04

申请号：US10540878

申请日：2004-01-08

申请人： Takayuki Kawaguchi ,  Hidenori Akatsuka ,  Toru Iijima ,  Tatsuya Watanabe ,  Jun Murakami ,  Takashi Mitsui

发明人： Takayuki Kawaguchi ,  Hidenori Akatsuka ,  Toru Iijima ,  Tatsuya Watanabe ,  Jun Murakami ,  Takashi Mitsui

IPC分类号： A61K31/498 ,  A61K31/4741 ,  C07D491/02

CPC分类号： C07D491/04 ,  C07D213/75

摘要： The present invention provides a condensed furan compound of the formula (I): wherein Ring X is benzene, pyridine, or the like; Y is an optionally substituted amino, an optionally substituted cycloalkyl, an optionally substituted aryl, an optionally substituted saturated heterocyclic group, an optionally substituted unsaturated heterocyclic group; A is a single bond, lower alkylene, lower alkenylidene, lower alkenylene or an oxygen atom; R3 is hydrogen or the like; and, R4 is hydrogen, or the like, or pharmaceutically acceptable salts thereof, which is useful as a medicament, particularly, as an activated blood coagulation factor X inhibitor.

摘要翻译： 本发明提供式（I）的缩合呋喃化合物：其中环X为苯，吡啶等; Y是任选取代的氨基，任选取代的环烷基，任选取代的芳基，任选取代的饱和杂环基，任选取代的不饱和杂环基; A是单键，低级亚烷基，低级亚烯基，低级亚烯基或氧原子; R 3是氢等; 和R 4是氢等，或其药学上可接受的盐，其可用作药物，特别是作为活化凝血因子X抑制剂。

公开(公告)号：US06201569B1

公开(公告)日：2001-03-13

申请号：US08868572

申请日：1997-06-04

申请人： Toshiyuki Kawashima ,  Mie Tomiuka ,  Tatsuya Watanabe ,  Shigeyuki Sano

发明人： Toshiyuki Kawashima ,  Mie Tomiuka ,  Tatsuya Watanabe ,  Shigeyuki Sano

IPC分类号： H04N1700

CPC分类号： H04N9/28 ,  H04N17/04

摘要： A system and method for controlling a video display blanking signal so as to maintain a full display screen while minimizing interference with the displayed picture. To control the blanking signal one or more photosensors are placed at the periphery of the display screen. When a CRT overscans the screen at a sensor's location, the light from the CRT is incident on the sensor and the sensor generates a signal proportional to the amount of incident light. The sensor signal is used to adjust the CRT scan such that the CRT scan covers the screen but does not degrade the displayed picture.

摘要翻译： 一种用于控制视频显示消隐信号以便保持全屏显示同时最小化对所显示图像的干扰的系统和方法。 为了控制消隐信号，一个或多个光电传感器放置在显示屏的周围。 当CRT在传感器的位置超过屏幕时，来自CRT的光入射到传感器上，并且传感器产生与入射光量成比例的信号。 传感器信号用于调整CRT扫描，使得CRT扫描覆盖屏幕，但不会降低显示的图像。

公开(公告)号：US09173902B2

公开(公告)日：2015-11-03

申请号：US12530617

申请日：2008-03-10

申请人： Tatsuya Watanabe ,  Ken Kato ,  Hiroshi Ueno ,  Yuko Haruta ,  Noriko Ueda ,  Toshimitsu Yoshioka

发明人： Tatsuya Watanabe ,  Ken Kato ,  Hiroshi Ueno ,  Yuko Haruta ,  Noriko Ueda ,  Toshimitsu Yoshioka

IPC分类号： A61K8/00 ,  A61K35/20 ,  A23C9/152 ,  A23K1/16 ,  A23K1/18 ,  A23L1/305 ,  A23L2/52 ,  A61K8/64 ,  A61K38/01 ,  A61Q19/02

CPC分类号： A61K35/20 ,  A23C9/1526 ,  A23K20/147 ,  A23K50/40 ,  A23L2/52 ,  A23L33/18 ,  A23L33/19 ,  A61K8/64 ,  A61K38/00 ,  A61K38/018 ,  A61K2800/92 ,  A61Q19/02

摘要： A skin-whitening agent offering an excellent whitening effect and being effective in preventing and treating age spots, freckles, etc., where such skin-whitening agent contains as its effective ingredient a whey protein hydrolyzate characterized by a molecular weight distribution of 10 kDa or less, main peak of 200 Da to 3 kDa, APL (average peptide-chain length) of 2 to 8, free amino acid content of 20% or less, and antigenicity of one-ten thousandth of β-lactoglobulin or less, as well as a cosmetic, drink or food, feed, pharmaceutical preparation or other skin-whitening product containing such skin-whitening agent.

摘要翻译： 一种美白剂，其具有优异的美白效果，并有效预防和治疗老年斑，雀斑等，其中这样的皮肤增白剂作为其有效成分含有以10kDa分子量分布为特征的乳清蛋白水解产物，或 较少的主峰为200Da至3kDa，APL（平均肽链长度）为2至8，游离氨基酸含量为20％或更低，抗原性为万分之一以上的乳球蛋白或更少，为 以及化妆品，饮料或食品，饲料，药物制剂或含有这种皮肤增白剂的其它皮肤美白产品。

公开(公告)号：US20110124606A1

公开(公告)日：2011-05-26

申请号：US12743391

申请日：2008-11-19

申请人： Tatsuya Watanabe ,  Yuko Haruta ,  Ken Kato ,  Toshimitsu Yoshioka

发明人： Tatsuya Watanabe ,  Yuko Haruta ,  Ken Kato ,  Toshimitsu Yoshioka

IPC分类号： A61K31/688 ,  C07F9/10 ,  A61P17/00

CPC分类号： A61Q19/00 ,  A23K20/158 ,  A23K20/26 ,  A23K50/40 ,  A23L2/52 ,  A23L33/115 ,  A61K8/0212 ,  A61K8/553 ,  A61K8/68 ,  A61K31/688

摘要： Disclosed are: a sense-improving agent which comprises, as an active ingredient, a phospholipid or a sphingosine-containing phospholipid and/or a derivative thereof, particularly a sphingomyelin, and which has an effect of improving the dulling of senses at a periphery when ingested orally or directly applied to the skin; and a sense-improving food, beverage, feed or cosmetic comprising the sense-improving agent. The phospholipid to be used may be a chemically synthesized phospholipid or a naturally occurring phospholipid, preferably a phospholipid derived from an edible material such as soybean and egg yolk, particularly preferably a phospholipid derived from milk.

摘要翻译： 公开了一种感觉改善剂，其包含作为活性成分的磷脂或含鞘氨醇的磷脂和/或其衍生物，特别是鞘磷脂，并且具有改善周围感觉钝化的效果， 口服或直接施用于皮肤; 以及包含感官改善剂的感官改善食品，饮料，饲料或化妆品。 所使用的磷脂可以是化学合成的磷脂或天然存在的磷脂，优选来源于可食用物质如大豆和蛋黄的磷脂，特别优选来自牛奶的磷脂。