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    System and Method for Coating a Medical Device
    1.
    发明申请
    System and Method for Coating a Medical Device 有权
    医疗器械涂敷系统及方法

    公开(公告)号：US20110039013A1

    公开(公告)日：2011-02-17

    申请号：US12540302

    申请日：2009-08-12

    申请人： John E. Papp ,  Matthew J. Gillick ,  Kent C. B. Stalker

    发明人： John E. Papp ,  Matthew J. Gillick ,  Kent C. B. Stalker

    IPC分类号： B05D3/04 ,  B05C5/00 ,  B05C13/02 ,  B05C11/00

    CPC分类号： F26B9/06 ,  A61F2/82 ,  A61F2310/00389 ,  A61L2420/02 ,  B05B13/0221 ,  B05B13/0228 ,  B05B13/041 ,  B05B16/20 ,  B05B16/60 ,  B05B16/90 ,  B05D1/002 ,  B05D1/02 ,  B05D3/0413 ,  B05D3/0493 ,  B05D7/584

    摘要： A system and method allows for processing of two groups of medical devices, both groups being alternatingly spray coated within the same enclosure. The two groups repeatedly move back and forth between a spray area and a drying area which is isolated from the spray area. One group moves into the spray area as the other group moves out and into the drying area. Thereafter, the group in the spray area moves out and into the drying area and the other group moves back into the spraying area for a second coating. The alternating process may be repeated any number of times. The spray area may be located inside a sealed spray isolator enclosure and surrounded by gas discharge nozzles.

    摘要翻译： 一种系统和方法允许处理两组医疗装置，两组在相同外壳内交替喷涂。 两组反复在喷雾区域和与喷雾区域隔离的干燥区域之间来回移动。 随着另一组移出并进入干燥区域，一组移入喷雾区域。 此后，喷雾区域中的组移出并进入干燥区域，而另一组移回喷涂区域进行第二次涂覆。 交替过程可以重复任意次数。 喷射区域可以位于密封的喷雾隔离器外壳内并被气体排放喷嘴包围。

    Dryers For Removing Solvent From A Drug-Eluting Coating Applied To Medical Devices
    3.
    发明申请
    Dryers For Removing Solvent From A Drug-Eluting Coating Applied To Medical Devices 有权
    用于从药物洗脱涂层中除去溶剂的干燥器应用于医疗器械

    公开(公告)号：US20130071549A1

    公开(公告)日：2013-03-21

    申请号：US13235238

    申请日：2011-09-16

    申请人： Yung-Ming Chen ,  Matthew J. Gillick ,  Michael T. Martins ,  John E. Papp

    发明人： Yung-Ming Chen ,  Matthew J. Gillick ,  Michael T. Martins ,  John E. Papp

    IPC分类号： A61L33/00 ,  F26B25/06 ,  B05C13/02

    CPC分类号： F26B25/066 ,  F26B9/003

    摘要： A coating device for coating a medical device with a drug-eluting material uses an in-process drying station between coats to improve a drug release profile. The drying station includes a dryer having a telescoping plenum which provides a drying chamber for the stent or scaffold to reside while a heated gas is passed over the stent/scaffold. The drying chamber improves efficiency in drying, predictability or drug release rate, uniformity of coating material properties lengthwise over the stent/scaffold and provides a platform that can effectively support stents that are over 40 mm in length.

    摘要翻译： 用药物洗脱物质涂覆医疗装置的涂覆装置使用涂层之间的过程中的干燥站来改善药物释放曲线。 干燥站包括具有伸缩式增压室的干燥器，其提供用于支架或支架的干燥室，同时加热的气体通过支架/支架。 干燥室可以提高干燥效率，可预测性或药物释放速率，涂层材料性能在支架/支架上的长度均匀性，并提供可有效支撑长度超过40 mm的支架的平台。

    System and method for coating a medical device
    5.
    发明授权
    System and method for coating a medical device 有权
    用于涂覆医疗装置的系统和方法

    公开(公告)号：US08567340B2

    公开(公告)日：2013-10-29

    申请号：US12540302

    申请日：2009-08-12

    申请人： John E. Papp ,  Matthew J. Gillick ,  Kent C. B. Stalker

    发明人： John E. Papp ,  Matthew J. Gillick ,  Kent C. B. Stalker

    IPC分类号： B05C5/02

    CPC分类号： F26B9/06 ,  A61F2/82 ,  A61F2310/00389 ,  A61L2420/02 ,  B05B13/0221 ,  B05B13/0228 ,  B05B13/041 ,  B05B16/20 ,  B05B16/60 ,  B05B16/90 ,  B05D1/002 ,  B05D1/02 ,  B05D3/0413 ,  B05D3/0493 ,  B05D7/584

    摘要： A system and method allows for processing of two groups of medical devices, both groups being alternatingly spray coated within the same enclosure. The two groups repeatedly move back and forth between a spray area and a drying area which is isolated from the spray area. One group moves into the spray area as the other group moves out and into the drying area. Thereafter, the group in the spray area moves out and into the drying area and the other group moves back into the spraying area for a second coating. The alternating process may be repeated any number of times. The spray area may be located inside a sealed spray isolator enclosure and surrounded by gas discharge nozzles.

    摘要翻译： 一种系统和方法允许处理两组医疗装置，两组在相同外壳内交替喷涂。 两组反复在喷雾区域和与喷雾区域隔离的干燥区域之间来回移动。 随着另一组移出并进入干燥区域，一组移入喷雾区域。 此后，喷雾区域中的组移出并进入干燥区域，而另一组移回喷涂区域进行第二次涂覆。 交替过程可以重复任意次数。 喷射区域可以位于密封的喷雾隔离器外壳内并被气体排放喷嘴包围。

    Cold collapse method and apparatus
    8.
    发明申请
    Cold collapse method and apparatus 审中-公开
    冷塌方法和装置

    公开(公告)号：US20080072653A1

    公开(公告)日：2008-03-27

    申请号：US11524133

    申请日：2006-09-20

    申请人： Matthew J. Gillick ,  John E. Papp

    发明人： Matthew J. Gillick ,  John E. Papp

    IPC分类号： B21J7/16

    CPC分类号： A61F2/95 ,  A61F2002/9522 ,  F25D3/10

    摘要： A system and method are disclosed for collapsing medical devices, such as self-expanding, drug-eluting stents for loading into delivery catheters. The collapsing apparatus may be used for crimping expandable stents and other devices onto a balloon catheter. The medical device is cooled below the austenitic phase transformation temperature of the material forming the device, such as stainless steel or nitinol, and may be cooled until the material has fully transformed to the martenstitic state. For coated medical devices, the device is warmed to a temperature just below the beginning of austenite phase transformation prior to collapsing. An apparatus having a plurality of offset blades, linear bearings, radial bearings and an actuator mechanism is provided for collapsing the medical device. The system is configured with a mandrel subassembly to push the medical device into a catheter sheath, and with a nozzle subassembly to direct cold gas to the medical device.

    摘要翻译： 公开了用于折叠医疗装置的系统和方法，所述医疗装置例如用于装载到输送导管中的自扩张药物洗脱支架。 塌缩装置可用于将可扩张支架和其它装置卷曲到球囊导管上。 将医疗装置冷却到形成装置的材料（例如不锈钢或镍钛诺）的奥氏体相变温度以下，并且可以冷却直到材料完全转变为马氏体状态。 对于涂覆的医疗装置，在折叠之前将装置升温到刚好低于奥氏体相变开始的温度。 提供具有多个偏移叶片，直线轴承，径向轴承和致动器机构的装置，用于使医疗装置折叠。 该系统配置有心轴子组件以将医疗装置推入导管护套中，并且具有喷嘴子组件以将冷气引导到医疗装置。

    Embolic filtering devices
    10.
    发明授权
    Embolic filtering devices 有权
    栓塞过滤装置

    公开(公告)号：US08591540B2

    公开(公告)日：2013-11-26

    申请号：US10675611

    申请日：2003-09-29

    申请人： William J. Boyle ,  John E. Papp ,  Charles R. Peterson ,  Paul F. Muller ,  Donald Schwarten ,  Kathern J. Lind

    发明人： William J. Boyle ,  John E. Papp ,  Charles R. Peterson ,  Paul F. Muller ,  Donald Schwarten ,  Kathern J. Lind

    IPC分类号： A61M29/00

    CPC分类号： A61F2/013 ,  A61F2/97 ,  A61F2002/011 ,  A61F2002/015 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/008

    摘要： An embolic filtering system includes a guide wire, a filter device disposed on the guide wire, a sheath adapted to maintain the filter device in an unexpanded position and a torque device having a lumen for receiving the guide wire and a locking mechanism for locking the torque device to the guide wire. The torque device may include a side port adapted to receive the proximal end of the sheath to allow a portion of the guide wire to shear the sheath from the guide wire through retraction of the sheath through the side port. The torque device may include an extension arm having a distal opening adapted to receive both the guide wire and the sheath. A second lumen may be used to allow a portion of the guide wire to shear the sheath away from the guide wire through retraction of the sheath through the second lumen.

    摘要翻译： 栓塞过滤系统包括引导线，设置在引导线上的过滤器装置，适于将过滤装置保持在未膨胀位置的护套和具有用于容纳引导线的内腔的扭矩装置和用于锁定扭矩的锁定机构 设备到导丝。 扭矩装置可以包括适于容纳护套的近端的侧端口，以允许导线的一部分通过护套通过侧端部缩回而从引导线剪切护套。 扭矩装置可以包括延伸臂，其具有适于接纳导丝和护套的远端开口。 可以使用第二内腔来允许引导线的一部分通过使护套通过第二内腔缩回而将护套从引导线上剪切。