-
公开(公告)号：US07517352B2
公开(公告)日：2009-04-14
申请号：US09820084
申请日：2001-03-27
IPC分类号： A61M29/00
CPC分类号： A61B17/3207 , A61B17/22 , A61B17/221 , A61B17/32002 , A61B17/320725 , A61B17/32075 , A61B17/320783 , A61B2017/00287 , A61B2017/00362 , A61B2017/320004 , A61B2017/320044 , A61B2017/320741 , A61M25/1002 , A61M25/1027 , A61M29/02 , A61M2025/1015 , A61M2025/1088 , A61M2025/109
摘要： The present invention provides devices, systems, methods and kits for the percutaneous removal of unwanted tissue or obstructive matter from body cavities or lumens, particularly from the vasculature. Blood vessels, including the coronary, peripheral and neurovascular circulation, which are narrowed or blocked by atheromatous material or plaque are often treated with traditional endarterectomy procedures. The present invention allows the benefits of such a procedure with an intraluminal approach, particularly a percutaneous approach. Generally, the present invention provides a set of catheters or tools which are percutaneously introduceable to the site of the blockage or occlusion. The tools dissect or cut through the innermost tissue layer of the lumen to an underlying tissue layer. The innermost tissue layer is then stripped away from the underlying layer with the occlusive material thereattached. The detached tissue layer and occlusive material is then removed from the lumen; this may include additional cutting, maceration and removal through mechanical aspiration. In any case, the resulting lumen is free of obstruction.
摘要翻译： 本发明提供用于经皮去除不想要的组织或阻塞物质的装置，系统，方法和试剂盒，所述装置，系统，方法和试剂盒用于从体腔或腔，特别是脉管系统中去除。 通常使用传统的内膜切除手术治疗包括动脉粥样硬化材料或斑块变窄或阻塞的冠状动脉，周围和神经血管循环的血管。 本发明允许使用腔内方法，特别是经皮方法的这种手术的益处。 通常，本发明提供一组导管或工具，其经皮可引入阻塞部位或闭塞部位。 该工具将内腔的最内层组织切割或切割到下面的组织层。 然后将最内侧的组织层从附近的闭塞材料剥离下来的层。 然后从管腔移除脱离的组织层和封闭材料; 这可能包括通过机械抽吸进行额外的切割，浸渍和去除。 在任何情况下，所得到的内腔没有阻塞。
-
公开(公告)号：US06635070B2
公开(公告)日：2003-10-21
申请号：US09862174
申请日：2001-05-21
申请人： Stephen Leeflang , Denise DeMarais , Michael Evans
发明人： Stephen Leeflang , Denise DeMarais , Michael Evans
IPC分类号： A61M2900
CPC分类号： A61B17/22 , A61B17/32037 , A61B2017/22084 , A61B2217/005 , A61B2217/007 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/0076 , A61F2230/008 , A61F2230/0093 , A61F2250/0003
摘要： An apparatus includes a jet housing including an inlet and an outlet, and a nozzle within the jet housing for injecting fluid towards the outlet. A filter element is disposed on the inlet, the filter element including openings for preventing particulate larger than a predetermined size from entering the inlet. The jet housing is positioned within a blood vessel, and fluid is injected from the nozzle towards the outlet to create a vacuum at the inlet, thereby causing fluid downstream of the outlet to flow retrograde through the vessel around the jet housing into the inlet. The filter element prevents particulate from entering the inlet, thereby effectively capturing the particulate, which may be aspirated. Alternatively, a filter element is used to filter particulate during a procedure. The filter element everts from a tubular to an everted configuration for capturing particulate.
-
公开(公告)号：US06929633B2
公开(公告)日：2005-08-16
申请号：US10278735
申请日：2002-10-21
申请人： Michael A. Evans , Denise Demarais , Dino De Cicco , Kelvin Ning , Alexander Khairkhahan , Tyler Jon Strang , Jody Maria Cimbalo , Stephen Leeflang
发明人： Michael A. Evans , Denise Demarais , Dino De Cicco , Kelvin Ning , Alexander Khairkhahan , Tyler Jon Strang , Jody Maria Cimbalo , Stephen Leeflang
CPC分类号： A61B17/320758 , A61B17/22 , A61B17/22004 , A61B2017/00685 , A61B2017/22054 , A61B2017/22067 , A61B2017/22084 , A61B2017/320716 , A61B2017/320766 , A61M25/0021 , A61M25/007 , A61M25/0075 , A61M25/0105 , A61M39/22 , A61M2025/1052
摘要： Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, agitate the clot and agent, and aspirate broken-up clot from the blood vessel. A flow resistor in the catheter provides for infusion and/or aspiration to be concentrated primarily at a clot treatment area in a blood vessel while also providing optional infusion and/or aspiration distal to the treatment area. In some embodiments, infusion, aspiration and guidewire passage occur through a common lumen. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.
摘要翻译： 使用具有注入溶栓剂，搅动凝块和药剂的能力的导管，以及从血管中抽出破碎的凝块来实现凝块破裂和溶解。 导管中的流阻器提供输注和/或抽吸主要集中在血管中的凝块治疗区域，同时还提供可选的输液和/或远离治疗区域的抽吸。 在一些实施例中，输注，抽吸和导丝通过共同内腔。 血栓溶解剂如tPA，链激酶或尿激酶在搅拌器与凝块接合的位置处直接释放到凝块中。 以这种方式，药剂的溶栓活性增强，并且凝块的溶解得到改善。
-
公开(公告)号：US20050149104A1
公开(公告)日：2005-07-07
申请号：US10958034
申请日：2004-10-04
申请人： Stephen Leeflang , Christine Ventura , Christian Eversull , Nicholas Mourlas , Christopher Loew
发明人： Stephen Leeflang , Christine Ventura , Christian Eversull , Nicholas Mourlas , Christopher Loew
CPC分类号： A61M25/0662 , A61B17/3439 , A61M25/003 , A61M2025/0024 , A61M2025/0035 , A61N1/056
摘要： Apparatus and methods are provided for providing access to a body lumen. The apparatus includes a tubular member including a proximal end, a distal end sized for insertion into a body lumen, and a lumen extending between the proximal and distal ends. A pushable stiffening member extends from the distal end of the tubular member, the elongate member terminating in a distal tip. An expandable sheath extends along at least a portion of the stiffening member, the sheath being expandable from a contracted condition to minimize a profile of the sheath to allow insertion along with the stiffening member into a body lumen, and an enlarged condition wherein the sheath at least partially defines a lumen communicating with the tubular member lumen. In one embodiment, the sheath includes an outer lumen and an inner lumen floating within the outer lumen, and the stiffening member is carried in the inner lumen.
摘要翻译： 提供了用于提供对体腔的接近的装置和方法。 该装置包括管状构件，其包括近端，尺寸适于插入体腔的远端以及在近端和远端之间延伸的内腔。 可推动加强构件从管状构件的远端延伸，细长构件终止于远端。 可扩张护套沿着加强构件的至少一部分延伸，护套可以从收缩状态扩展，以最小化护套的轮廓，以允许将加强构件插入体腔内，并且扩大状态，其中护套 至少部分地限定与所述管状构件内腔连通的管腔。 在一个实施例中，护套包括外腔和漂浮在外腔内的内腔，并且加强构件承载在内腔中。
-
5.发明申请公开(公告)号：US20070169877A1
公开(公告)日：2007-07-26
申请号：US11670958
申请日：2007-02-02
IPC分类号： B32B37/00
CPC分类号： A61M25/0009 , A61L29/085 , A61L29/14 , A61M25/0045 , A61M25/005 , A61M2025/0046 , A61M2025/0047 , A61M2025/0048 , A61M2025/006 , A61N1/056 , B29C47/0014 , B29C47/0028 , B29C47/0033 , B29C53/40 , B29C53/46 , B29C61/006 , B29C66/112 , B29C66/1122 , B29C66/1142 , B29C66/133 , B29C66/135 , B29C66/432 , B29C66/4322 , B29C66/438 , B29C66/49 , B29C66/52272 , B29C66/71 , B29C66/723 , B29C67/0018 , B29C69/001 , B29C2793/009 , B29D23/001 , B29L2031/602 , B29L2031/753 , B29L2031/7542 , B32B1/08 , B32B5/028 , B32B27/08 , B32B27/12 , B32B27/285 , B32B27/34 , B32B27/40 , B32B2250/24 , B32B2255/10 , B32B2255/26 , B32B2262/0269 , B32B2262/101 , B32B2262/103 , B32B2307/728 , B32B2307/736 , B32B2307/746 , B32B2535/00 , Y10T156/1008 , Y10T156/101 , Y10T156/1038 , Y10T156/1054 , Y10T156/1062 , Y10T156/1066 , Y10T156/1313 , Y10T156/1322 , C08L75/04 , B29K2075/00
摘要： Apparatus and methods are provided for substantially continuously forming thin-walled sleeves that may be incorporated into tubular devices sized for introduction into a patient. In one embodiment, a pair of sheets including coated surfaces oriented towards one another are directed through a cutting apparatus to cut the sheets into multiple pairs of strips. The pairs of strips are bonded together to create a plurality of sleeves having lumens defined by the coated surfaces. In another embodiment, a sheet having a coated surface is fed through a cutting tool to separate the sheet into a plurality of strips, and the strips are formed into sleeves, e.g., by feeding the strips through a die or mandrel using a substantially continuous process. Optionally, the sleeves may be subsequently cut into individual tubular devices and/or further processed, e.g., by providing one or more layers around the sleeves to create catheters, sheaths, or other apparatus.
摘要翻译： 提供了用于基本上连续地形成薄壁套筒的装置和方法，所述薄壁套筒可并入到尺寸适于引入患者体内的管状装置中。 在一个实施例中，包括朝向彼此定向的涂覆表面的一对片材被引导通过切割装置以将片材切割成多对条带。 这些条带被粘合在一起以产生多个具有被涂覆表面限定的腔的套筒。 在另一个实施例中，具有涂覆表面的片材通过切割工具进给以将片材分离成多个条带，并且条形成为套筒，例如通过使用基本连续的方法将条带穿过模具或心轴 。 任选地，可以随后将套管切割成单独的管状装置和/或进一步加工，例如通过围绕套管提供一个或多个层以产生导管，护套或其它装置。
-
6.发明申请公开(公告)号：US20070088296A1
公开(公告)日：2007-04-19
申请号：US11341324
申请日：2006-01-26
IPC分类号： A61M25/00
CPC分类号： A61M25/0045 , A61L29/085 , A61L29/14 , A61M25/0009 , A61M2025/0046 , C08L75/04
摘要： Coated devices for introduction into bodies and methods for making and using them are provided, such as delivery sheaths, guidewire lumen cores, and elongate leads. In one embodiment, a tubular device includes a proximal end, a distal end sized for introduction into a body lumen, and a lumen extending between the proximal and distal ends. The tubular device includes a relatively thin inner polyurethane liner including a coating on an inner surface thereof, e.g., providing a lubricious and/or hydrophilic lumen, and an outer layer surrounding the liner. In another embodiment, a lead is provided that includes a proximal end, a distal end, and at least one electrode on the distal end. A polyurethane cover surrounds at least a portion of an outer surface of the lead that include a coating, e.g., including a lubricious and/or hydrophilic material. Optionally, the cover may be removable from around the lead body.
摘要翻译： 提供用于引入主体的涂覆装置和用于制造和使用它们的方法，例如输送护套，导丝管芯芯和细长引线。 在一个实施例中，管状装置包括近端，尺寸适于引入体腔的远端和在近端和远端之间延伸的内腔。 管状装置包括相对薄的内部聚氨酯衬里，其包括在其内表面上的涂层，例如提供润滑和/或亲水的内腔以及围绕衬垫的外层。 在另一个实施例中，提供了一种引线，其包括近端，远端和远端上的至少一个电极。 聚氨酯覆盖物包围引线的外表面的至少一部分，其包括涂层，例如包括润滑和/或亲水材料。 可选地，盖可以从引线主体周围移除。
-
7.发明申请公开(公告)号：US20080015625A1
公开(公告)日：2008-01-17
申请号：US11746639
申请日：2007-05-09
IPC分类号： A61M29/00
CPC分类号： A61M25/0097 , A61B17/3439 , A61M25/0147 , A61M25/0152 , A61M25/0662 , A61M2025/0024 , A61N1/056 , A61N2001/0585
摘要： Apparatus and methods are provided for providing access to a body lumen, e.g., to deliver a pacing lead within a patient's heart. The apparatus includes a tubular member including a proximal end, a distal end sized for insertion into a body lumen, and a lumen extending therebetween. An elongate member extends from the distal end of the tubular member. An expandable sheath extends along at least a portion of the elongate member, the sheath being expandable from a contracted condition to facilitate insertion into a body lumen, and an enlarged condition wherein the sheath at least partially defines a lumen communicating with the tubular member lumen. A stylet or other shaped element is insertable into the elongate member for changing a shape of at least a distal tip of the elongate member, e.g., for accessing side branches extending from a body lumen, e.g., within a patient's coronary venous system.
摘要翻译： 提供了用于提供对体腔的接近的装置和方法，例如将患者心脏内的起搏引线输送。 该装置包括管状构件，该管状构件包括近端，尺寸适于插入体腔的远端和在其间延伸的内腔。 细长构件从管状构件的远端延伸。 可扩张护套沿着细长构件的至少一部分延伸，护套可以从收缩状态扩展以便于插入体腔，以及扩大状态，其中护套至少部分地限定与管状构件腔连通的内腔。 探针或其他形状的元件可插入到细长构件中，用于改变细长构件的至少远侧末端的形状，例如用于进入从体腔延伸的侧分支，例如在病人的冠状静脉系统内。
-
公开(公告)号：US20070083217A1
公开(公告)日：2007-04-12
申请号：US11465123
申请日：2006-08-16
CPC分类号： A61B17/3468 , A61B1/00073 , A61B1/00082 , A61B1/00154 , A61B1/0051 , A61B1/018 , A61B1/05 , A61B1/051 , A61B1/053 , A61B1/3137 , A61B17/00234 , A61B2017/00243 , A61B2017/00296 , A61B2017/3488 , A61B2090/3614 , A61M25/09 , A61M2025/0177 , A61N1/056 , A61N1/057 , A61N1/0587 , A61N1/059
摘要： An apparatus for imaging a body structure within a body cavity includes a catheter including proximal and distal ends, an imaging element on the distal end, and an extension extending distally from the distal end for contacting a surface of a body cavity into which the catheter is introduced. The extension has a length to maintain the optical imaging element away from the surface. Optionally, a transparent member, e.g., an expandable balloon, may be attached to the distal end of the tubular member and the extension to isolate the imaging element from contact with fluid within the body cavity. During use, the catheter is inserted into a chamber of a beating heart, and the extension and/or balloon is placed against the wall of the chamber. Sufficient force is applied to stabilize the imaging element relative to the wall while the heart is beating.
摘要翻译： 用于对体腔内的身体结构进行成像的装置包括：导管，其包括近端和远端;远端上的成像元件;以及从远端向远侧延伸的延伸部，用于接触体腔的表面，导管为 介绍。 延伸部具有使光学成像元件远离表面的长度。 任选地，透明构件，例如可膨胀气囊，可以附接到管状构件的远端并且延伸部分以隔离成像元件与体腔内的流体的接触。 在使用期间，将导管插入跳动心脏的腔室中，并且延伸部和/或气囊抵靠腔室的壁放置。 当心脏跳动时，施加足够的力来稳定成像元件相对于壁。
-
公开(公告)号：US20070043413A1
公开(公告)日：2007-02-22
申请号：US11465113
申请日：2006-08-16
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N1/0573 , A61N2001/0585
摘要： Apparatus and methods are provided for delivering a lead over a rail into a target body lumen, cavity, or other vessel, e.g., a coronary vein or a right ventricle within a patient's heart. For example, a distal end of an elongate guidewire or other rail may be introduced into the coronary venous system via the coronary sinus, advanced through the coronary venous system to a location beyond a target vessel, and secured at the location beyond the target vessel. A catheter or other elongate tubular member is advanced over the rail and manipulated to position an outlet of the tubular member adjacent to or otherwise aligned relative to the target vessel. A distal end of a lead is delivered through the tubular member and out the outlet into the target vessel. The catheter and rail are then removed, leaving the lead within the target vessel.
摘要翻译： 提供了一种装置和方法，用于将轨道上的导线输送到患者心脏内的目标体腔，空腔或其它血管，例如冠状静脉或右心室。 例如，细长导丝或其他导轨的远端可以经由冠状静脉系统通过冠状静脉系统引入冠状静脉系统到超过目标血管的位置，并且固定在超过目标血管的位置。 导管或其他细长的管状构件在轨道上前进并被操纵以将管状构件的出口定位成与靶容器相邻或相对于靶容器对准。 引线的远端通过管状部件输送出出口进入目标容器。 然后取出导管和导轨，将引线留在目标血管内。
-
10.发明申请公开(公告)号：US20070016130A1
公开(公告)日：2007-01-18
申请号：US11382026
申请日：2006-05-06
CPC分类号： A61M25/0105 , A61B1/00165 , A61M25/0023 , A61M25/0032 , A61M25/005 , A61M25/0147 , A61M25/10 , A61M2025/0036 , A61M2025/0161
摘要： Apparatus and methods are provided for accessing a body lumen within a patient's body. Generally, the apparatus includes a tubular member including proximal and distal ends, a steering element extending between the proximal and distal ends, and an actuator for directing the distal end between a relaxed configuration and a complex curved configuration. In the relaxed configuration, the distal end may assume a straight or curved shape. In the complex curved configuration, the distal end may assume a curvilinear shape. In one embodiment, the complex curved configuration may include a first curved portion defining an arc within a plane, and a second portion that extends out of the plane. An embodiment with a left hand rule configuration may be introduced into the right atrium of a heart from a superior approach, and the complex curved configuration may facilitate accessing the coronary sinus.
摘要翻译： 提供了用于访问患者身体内的体腔的装置和方法。 通常，该装置包括管状构件，其包括近端和远端，在近端和远端之间延伸的操纵元件和用于将远端引导在松弛构型和复合弯曲构型之间的致动器。 在松弛构造中，远端可呈直线或弯曲形状。 在复杂的弯曲构型中，远端可呈现曲线形状。 在一个实施例中，复合弯曲构造可以包括在平面内限定弧的第一弯曲部分和延伸出平面的第二部分。 具有左手规则配置的实施例可以从优越的方法引入心脏的右心房，并且复曲线配置可以有助于进入冠状窦。
-
-
-
-
-
-
-
-
-
搜索结果
20 条记录 (耗时 0.025 秒)