摘要:
Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices may be accomplished via stabilized implantable systems and ingestible pills. In one aspect, a method of inducing satiety includes implanting an implant within a lumen of a gastrointestinal tract and retaining a portion of chyme that flows by the implant within a body of the implant. The method further involves re-releasing the retained chyme from the implant into the gastrointestinal tract at a predetermined rate slower than a rate caused by natural peristalsis.
摘要:
A medical device comprises a handle comprises an actuator. A shaft extends distally from the handle. A first shaft segment extends proximally from the handle and has a proximal end and a distal end. A second shaft segment has a proximal end and a distal end and is pivotably supported with respect to the distal end of the first shaft segment at a position offset from a longitudinal axis of the shaft in a first offset direction. A third shaft segment has a proximal end and a distal end and is pivotably supported with respect to the distal end of the second shaft segment at a position offset from the longitudinal axis of the shaft in a second offset direction different from the first offset direction. A first member extends through at least a portion of the first shaft segment and is operatively associated with the actuator. A second member extends through at least a portion of the second shaft segment. The second member has a proximal end pivotably supported with respect to the distal end of the first member and a distal end pivotably supported with respect to the third shaft segment. The actuator is operative to provide substantially simultaneous compound articulation of the second and third shaft segments.
摘要:
Methods and devices are provided for performing minimally invasive surgical procedures. In one embodiment, a surgical device is provided that includes an elongate shaft having a distal portion configured to be movable between a first configuration in which the distal portion of the shaft is substantially straight or linear and a second configuration in which the distal portion of the shaft is bent at a compound angle. The shaft's distal portion can be configured to be articulated in a wide range of compound angles and can be configured to be selectively locked in a fixed position anywhere within that range.
摘要:
A surgical or diagnostic camera system is disclosed that has a disposable cap-like device that is structured for removal of adhesions while under direct visualization with the camera. The adhesion removal device may have an electrode on the tip that can be activated to enhance separation of tissues and may be configured to securely snap on to the housing of the camera system.
摘要:
Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.
摘要:
A method for inducing satiety using the steps of inserting an elongated device into a patient through a natural orifice and into a stomach of the patient, placing a distal end of the elongated device adjacent a treatment site within the stomach, and delivering at least one space occupying member through the elongated device adjacent the treatment site and implanting the at least one space occupying member between the submucosal and muscularis layers at the target site.
摘要:
A staple having a crown, a deformable leg extending from the crown, and a spring extending from the crown configured to compress tissue between the spring and the deformable member. Owing to the flexibility of the spring, the staple can accommodate a wide range of tissue thicknesses while still compressing the tissue captured therein. As a result, a single staple design can be used in a wide variety of surgical procedures thereby reducing the amount of staple designs that must be provided to the surgeon. In at least one embodiment, the staple includes a crushable member. This crushable member can include a plastically deformable first portion and an elastically deformable second portion. The present invention can also include, in various embodiments, a crown, a first deformable member extending from the crown, and means for compressing the tissue against the first deformable member.
摘要:
A medical device comprises a handle comprises an actuator. A shaft extends distally from the handle. A first shaft segment extends proximally from the handle and has a proximal end and a distal end. A second shaft segment has a proximal end and a distal end and is pivotably supported with respect to the distal end of the first shaft segment at a position offset from a longitudinal axis of the shaft in a first offset direction. A third shaft segment has a proximal end and a distal end and is pivotably supported with respect to the distal end of the second shaft segment at a position offset from the longitudinal axis of the shaft in a second offset direction different from the first offset direction. A first member extends through at least a portion of the first shaft segment and is operatively associated with the actuator. A second member extends through at least a portion of the second shaft segment. The second member has a proximal end pivotably supported with respect to the distal end of the first member and a distal end pivotably supported with respect to the third shaft segment. The actuator is operative to provide substantially simultaneous compound articulation of the second and third shaft segments.
摘要:
A method for regulating hormone production comprises placing at least one electrode in a gastrointestinal tract of a patient and recording an electrical signal during a preselected event produced by the gastrointestinal tract. The method further involves the steps of storing the electrical signal, and playing back the electrical signal by activating the electrode during the absence of the preselected event.
摘要:
Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.