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53 条记录 (耗时 0.03 秒)

    Methods of repairing tandemly repeated DNA sequences and extending cell life-span nuclear transfer
    8.
    发明申请
    Methods of repairing tandemly repeated DNA sequences and extending cell life-span nuclear transfer 审中-公开
    修复串联重复DNA序列和延长细胞寿命核转移的方法

    公开(公告)号：US20050255596A1

    公开(公告)日：2005-11-17

    申请号：US11079930

    申请日：2005-03-09

    申请人： Michael West ,  Robert Lanza ,  Jose Cibelli

    发明人： Michael West ,  Robert Lanza ,  Jose Cibelli

    IPC分类号： C12N5/08 ,  C12N15/63 ,  C12N15/85 ,  C12Q1/68

    CPC分类号： C12N15/85 ,  C12N2517/04

    摘要： This invention relates to methods for rejuvenating normal somatic cells and for making normal somatic cells of a different type having the same genotype as a normal somatic cell of interest. These cells have particular application in cell and tissue transplantation. Also encompassed are methods of re-cloning cloned animals, particularly methods where the offspring of cloned mammals are designed to be genetically altered in comparison to their cloned parent, e.g., that are “hyper-young.” These animals should be healthier and possess desirable properties relative to their cloned parent. Also included are methods for activating endogenous telomerase, EPC-1 activity, and or the ALT pathway and/or extending the life-span of a normal somatic cell, and other genes associated with cell aging and proliferation capacity.

    摘要翻译： 本发明涉及用于恢复正常体细胞和用于制备具有与感兴趣的正常体细胞相同基因型的不同类型的正常体细胞的方法。 这些细胞在细胞和组织移植中具有特殊应用。 还包括重新克隆克隆动物的方法，特别是其克隆的哺乳动物的后代被设计为与其克隆的亲本（例如“超年龄”）相比被遗传改变的方法。 这些动物应该更健康，并且相对于其克隆的亲本具有所需的性质。 还包括用于激活内源性端粒酶，EPC-1活性和/或ALT途径和/或延长正常体细胞的寿命和与细胞衰老和增殖能力相关的其它基因的方法。

    Synergistic metal salt-cationic surfactant-organic biocide composition
    9.
    发明申请
    Synergistic metal salt-cationic surfactant-organic biocide composition 审中-公开
    协同金属盐 - 阳离子表面活性剂 - 有机杀菌剂组合物

    公开(公告)号：US20050053672A1

    公开(公告)日：2005-03-10

    申请号：US10657030

    申请日：2003-09-08

    申请人： Michael West

    发明人： Michael West

    IPC分类号： A01N59/06 ,  A01N59/16

    CPC分类号： A01N59/06 ,  A01N43/653 ,  A01N33/08 ,  A01N25/30 ,  A01N2300/00

    摘要： A biocide composition comprising (a) about 0.05% to about 75% of an acidic metal salt selected from the metal group consisting of aluminum, iron, manganese, and zirconium; (b) about 0.05% to about 75% of a cationic surfactant; and (c) about 0.0001% to about 25% of an organic biocide.

    摘要翻译： 一种杀生物剂组合物，其包含（a）约0.05％至约75％的选自铝，铁，锰和锆的金属中的酸性金属盐; （b）约0.05％至约75％的阳离子表面活性剂; 和（c）约0.0001％至约25％的有机杀生物剂。

    Module for automated matrix removal
    10.
    发明申请
    Module for automated matrix removal 失效
    自动矩阵去除模块

    公开(公告)号：US20050036917A1

    公开(公告)日：2005-02-17

    申请号：US10641946

    申请日：2003-08-15

    申请人： Marc Anderson ,  Michael West ,  James Tappan

    发明人： Marc Anderson ,  Michael West ,  James Tappan

    IPC分类号： G01N1/28 ,  G01N1/34 ,  G01N31/02 ,  H01J49/04 ,  B01L3/00

    CPC分类号： G01N31/02 ,  G01N1/34 ,  G01N1/4077 ,  H01J49/04 ,  Y10T436/25375

    摘要： An automated matrix removal module is configurable to automatically withdraw a portion of sample containing an interferent. The module is further configurable to mix the portion of sample with a precipitating reagent selected to react with the interferent to form a precipitant and then filter mixture of sample and precipitant reagent through a filter. Finally, the module is further configurable to flush the precipitant from the filter.

    摘要翻译： 自动矩阵去除模块可配置为自动提取含有干扰物的样品的一部分。 该模块还可配置为将样品的一部分与选择的与沉淀剂反应的沉淀剂混合以形成沉淀剂，然后通过过滤器过滤样品和沉淀剂的混合物。 最后，该模块进一步可配置以从过滤器冲洗沉淀剂。