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    Optical noninvasive blood pressure sensor and method
    7.
    发明授权
    Optical noninvasive blood pressure sensor and method 有权
    光学无创血压传感器及方法

    公开(公告)号：US06533729B1

    公开(公告)日：2003-03-18

    申请号：US09569586

    申请日：2000-05-10

    申请人： Mohammad Khair ,  Salvador Lopez ,  Richard Ng ,  Sanjar Ghaem ,  William Olson

    发明人： Mohammad Khair ,  Salvador Lopez ,  Richard Ng ,  Sanjar Ghaem ,  William Olson

    IPC分类号： A61B502

    CPC分类号： A61B5/021 ,  A61B5/0013 ,  A61B5/681 ,  A61B5/7289 ,  A61B2562/0233 ,  A61B2562/046

    摘要： A blood pressure sensor includes a source of photo-radiation, such as an array of laser diodes. The sensor also includes a two-dimensional, flexible reflective surface. The reflective surface is nominally positioned relative to the radiation source such that the radiation travels in a direction normal to the reflective surface. The reflective surface is placed adjacent to the location on the patient where the blood pressure data is to be acquired. Radiation from the source is reflected off of the reflective surface onto a two-dimensional array of photo-detectors. Systolic and diastolic blood pressure fluctuations in the patient are translated into deflections of the patient's skin. These deflections cause corresponding deflections in the two dimensional reflective surface. The associated movement of said flexible reflective surface due to blood pulsation causes scattering patterns from said reflective surface to be detected by the two dimensional array of photo-detectors. The output from the array of photo-detectors is calibrated to blood pressure in mmHg during a calibration procedure to obtain a set of calibration relationships for one or more of the individual detectors. The calibration relationship are then used during acquisition of blood pressure data to arrive at blood pressure data.

    摘要翻译： 血压传感器包括光辐射源，例如激光二极管阵列。 该传感器还包括一个二维，柔性的反射表面。 反射表面相对于辐射源名义上定位，使得辐射沿垂直于反射表面的方向行进。 将反射表面放置在与要获取血压数据的患者上的位置相邻处。 来自源的辐射从反射表面反射到二维光电检测器阵列上。 患者的收缩压和舒张压波动被转化为患者皮肤的偏转。 这些偏转导致二维反射表面中相应的偏转。 由于血液脉动引起的所述柔性反射表面的相关运动导致来自所述反射表面的散射图案由光电检测器的二维阵列检测。 在校准过程期间，来自光电检测器阵列的输出被校准为以mmHg为单位的血压，以获得针对一个或多个单个检测器的一组校准关系。 然后在获取血压数据期间使用校准关系以获得血压数据。

    Method for obtaining blood pressure data from optical sensor
    8.
    发明授权
    Method for obtaining blood pressure data from optical sensor 有权
    从光学传感器获得血压数据的方法

    公开(公告)号：US06475153B1

    公开(公告)日：2002-11-05

    申请号：US09568781

    申请日：2000-05-10

    申请人： Mohammad Khair ,  Salvador Lopez ,  Richard Ng ,  Sanjar Ghaem ,  William Olson

    发明人： Mohammad Khair ,  Salvador Lopez ,  Richard Ng ,  Sanjar Ghaem ,  William Olson

    IPC分类号： A61B502

    CPC分类号： A61B5/6843 ,  A61B5/02007 ,  A61B5/021 ,  A61B5/02416 ,  A61B5/0261 ,  A61B5/681 ,  A61B5/7285 ,  A61B2562/0233 ,  A61B2562/046

    摘要： An optical sensor generates blood pressure data by obtaining two dimensional images of the surface of the patient's body, such as in the vicinity of the radial artery in the wrist area. Blood flow in the patient causes light to be reflected off a flexible reflective surface applied against the patient with a hold down pressure, and the scattering of light is sensed with a two-dimensional array of photo-detectors. The output of the photo-detectors during systolic and diastolic events is calibrated against known blood pressure measurements taken with a conventional air-cuff sphygmomanometer. Linear calibration relationships between output signal and blood pressure are obtained during calibration for some set of the photo-detectors. When blood pressure data is obtained from the patient, the linear calibration relationship between output signals and blood pressure is applied to the output signals from the set of photo-detectors, resulting in blood pressure data. The method provides for compensation for changes in hold down pressure and translation or rotation of the optical sensor relative to the patient. A preferred optical sensor arrangement for use in performing the method is also described.

    摘要翻译： 光学传感器通过获得患者身体的表面的二维图像，例如在手腕区域中的桡动脉附近来产生血压数据。 患者的血液流动导致光被从按压压力施加到患者上的柔性反射表面反射出来，并且用二维光电检测器阵列感测光的散射。 收缩期和舒张期事件期间光电探测器的输出是用常规气袖血压计测量的已知血压进行校准。 在一些光电检测器的校准期间，可以获得输出信号与血压之间的线性校准关系。 当从患者获得血压数据时，输出信号和血压之间的线性校准关系被施加到来自该组光电检测器的输出信号，从而产生血压数据。 该方法提供补偿压力压力和光学传感器相对于患者的平移或旋转的变化。 还描述了用于执行该方法的优选光学传感器装置。

    Battery-powered RF tags and apparatus for manufacturing the same
    9.
    发明授权
    Battery-powered RF tags and apparatus for manufacturing the same 失效
    电池供电的RF标签及其制造设备

    公开(公告)号：US5495250A

    公开(公告)日：1996-02-27

    申请号：US143583

    申请日：1993-11-01

    申请人： Sanjar Ghaem ,  William L. Olson ,  Rudyard L. Istvan ,  George L. Lauro

    发明人： Sanjar Ghaem ,  William L. Olson ,  Rudyard L. Istvan ,  George L. Lauro

    IPC分类号： G06K19/077 ,  H01M2/10 ,  H01M6/40 ,  G01S13/08

    CPC分类号： G06K19/0702 ,  G06K19/027 ,  G06K19/077 ,  G06K19/07718 ,  G06K19/07749 ,  G06K19/07779 ,  G06K19/07783 ,  H01M2/1022 ,  H01M6/40

    摘要： An RF tag (20) includes a low profile battery power source (22). The RF tag includes an electrically insulating substrate 21, an RF transmitter (24) on the substrate for transmitting a predetermined identification code, and the battery (22). The battery includes a first pattern of conductive material to form a planar anode structure (48) and a second pattern of conductive material on the substrate to form a cathode structure (50). A protective layer (92) overlies the substrate. The protective layer includes an opening (94) to expose the anode and cathode of the battery to permit an electrolyte to be applied to the anode and cathode for completing the formation of the battery and to provide electrical energy to the RF transmitter. A manufacturing apparatus (60) is also described which permits the RF tags to be manufactured in a low cost, reel-to-reel, basis. Also described is a dispenser (100) for activating and dispensing the RF tags one at a time at a point of use.

    摘要翻译： RF标签（20）包括薄型电池电源（22）。 RF标签包括电绝缘基板21，用于发送预定识别码的基板上的RF发射器（24）和电池（22）。 电池包括导电材料的第一图案，以在衬底上形成平面阳极结构（48）和第二导电材料图案以形成阴极结构（50）。 保护层（92）覆盖在基板上。 保护层包括用于暴露电池的阳极和阴极的开口（94），以允许将电解质施加到阳极和阴极以完成电池的形成并向RF发射器提供电能。 还描述了一种制造设备（60），其允许以低成本，卷到盘的方式制造RF标签。 还描述了一种用于在使用点一次一个地激活和分配RF标签的分配器（100）。