利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

21 条记录 (耗时 0.018 秒)

    Process for producing optically active 3-aminobutanoic acid and the ester intermediates
    4.
    发明授权
    Process for producing optically active 3-aminobutanoic acid and the ester intermediates 失效
    光学活性3-氨基丁酸和酯中间体的制备方法

    公开(公告)号：US5518903A

    公开(公告)日：1996-05-21

    申请号：US289031

    申请日：1994-08-11

    申请人： Naoyuki Yoshida ,  Teruyo Sugiura ,  Yasuyuki Koizumi

    发明人： Naoyuki Yoshida ,  Teruyo Sugiura ,  Yasuyuki Koizumi

    IPC分类号： C12P13/04 ,  C12P41/00 ,  C12R1/01 ,  C12R1/38 ,  C12N9/14 ,  C12N9/16

    CPC分类号： C12P41/005 ,  C12P13/04

    摘要： The present invention provides a process for producing optically active 3-aminobutanoic acid characterized in that it comprises an asymmetrically hydrolyzing racemic ester of 3-substituted aminobutanoic acid in the presence of a hydrolase, obtaining an optically active ester of 3-substituted aminobutanoic acid and an optically active 3-substituted aminobutanoic acid of an enantiomer of the ester, and treating the above ester represented by the formula (II): ##STR1## to remove the protecting group. In addition, the new ester intermediates represented by the above formula (II) are provided.

    摘要翻译： 本发明提供了一种光学活性3-氨基丁酸的制备方法，其特征在于，在水解酶存在下，其包含不对称水解的3-取代氨基丁酸的外消旋酯，得到3-取代氨基丁酸的光学活性酯和 光学活性的3-取代的氨基丁酸的酯的对映异构体，并处理由式（II）表示的上述酯：除去保护基。 此外，提供由上述式（II）表示的新的酯中间体。

    Process for producing an intermediate of a new quinolone compound
    8.
    发明授权
    Process for producing an intermediate of a new quinolone compound 失效
    制备新型喹诺酮化合物的中间体的方法

    公开(公告)号：US5623078A

    公开(公告)日：1997-04-22

    申请号：US666742

    申请日：1996-06-20

    申请人： Yasuo Urata ,  Mamoru Fujita ,  Teruyo Sugiura ,  Fumitaka Ohizumi ,  Naoyuki Yoshida

    发明人： Yasuo Urata ,  Mamoru Fujita ,  Teruyo Sugiura ,  Fumitaka Ohizumi ,  Naoyuki Yoshida

    IPC分类号： C07D209/52 ,  C07D209/02

    CPC分类号： C07D209/02

    摘要： A production process with good efficiency, and applicable to production of a synthetic intermediate of a new quinolone anti-fungus agent CP-99219, is provided.A production process of an intermediate of a new quinolone compound expressed by the formula (IV) ##STR1## wherein R.sup.3 represents a benzyl group, a diphenylmethyl group, etc. and R.sup.4 represents a linear or branched alkyl group of 1 to 8C, a cycloalkyl group, etc.which process employs as a starting substance, a cyclopropanetricarboxylic acid triester expressed by the formula (I) ##STR2## wherein R.sup.1 and R.sup.2 represent a linear or branched alkyl group, a cycloalkyl group, an aryl group or an aralkyl group,and passes through seven steps.

    摘要翻译： 提供了一种效率高，适用于生产新型喹诺酮类抗真菌剂CP-99219的合成中间体的生产方法。 由式（IV）表示的新型喹诺酮化合物的中间体（IV）的制备方法，其中R 3表示苄基，二苯基甲基等，R 4表示1〜8的直链或支链烷基 ，该方法用作起始物质的环烷基等，由式（I）表示的环丙烷三羧酸三酯，支化烷基，环烷基，芳基或芳烷基，并通过七个步骤。

    Liquid crystal compound having lactone ring, liquid crystal composition, and liquid crystal display device
    10.
    发明授权
    Liquid crystal compound having lactone ring, liquid crystal composition, and liquid crystal display device 有权
    具有内酯环的液晶化合物，液晶组合物和液晶显示装置

    公开(公告)号：US07875327B2

    公开(公告)日：2011-01-25

    申请号：US12572895

    申请日：2009-10-02

    申请人： Mayumi Goto ,  Teruyo Sugiura ,  Norikatsu Hattori

    发明人： Mayumi Goto ,  Teruyo Sugiura ,  Norikatsu Hattori

    IPC分类号： C09K19/34 ,  C09K19/30 ,  C07D309/16

    CPC分类号： C09K19/3402 ,  C09K19/42 ,  C09K2019/3422 ,  Y10T428/10

    摘要： A nematic liquid crystal compound represented by any one of formulas (a-1) to (a-6): in formulas (a-1) to (a-6), Ra and Rb are each independently hydrogen or alkyl having 1 to 10 carbons, provided that in the alkyl, —CH2- may be replaced by —O—, —(CH2)2- may be replaced by —CH═CH—, and hydrogen may be replaced by a halogen; ring A1 and ring A2 are each independently trans-1,4-cyclohexylene or 1,4-phenylene, provided that in these rings hydrogen may be replaced by a halogen, and in the case where the ring is trans-1,4-cyclohexylene, —CH2- may be replaced by —O—, and —CH2CH— may be replaced by —CH═C—; and Z1 and Z2 are each independently a single bond, —COO—, —OCO—, —OCH2-, —CH2O— or —CH2CH2-, provided that in formula (a-3), in the case where ring A2 is trans-1,4-cyclohexylene, Z2 is a single bond, —COO—, —OCO—, —OCH2- or —CH2O—, in the case where Ra is —C3H7, Rb is —OC2H5, and Z2 is a single bond, ring A2 is trans-1,4-cyclohexylene, 1,3-dioxane-2,5-diyl, 2-fluoro- 1,4-phenylene, 3-fluoro-1,4-phenylene, 2-fluoro-3-chloro-1,4-phenylene, 2-chloro- 3-fluoro-3,4-phenylene or 2,3-dichloro-1,4-phenylene, and in formula (a-4), in the case where ring A1 is trans-1,4-cyclohexylene, Z1 is a single bond, —COO—, —OCO—, —OCH2- or —CH2O—.

    摘要翻译： 由式（a-1）〜（a-6）中的任一个表示的向列型液晶化合物：在式（a-1）至（a-6）中，Ra和Rb各自独立地为氢或具有1〜10 碳原子，条件是在烷基中，-CH 2 - 可以被-O - 取代， - （CH 2）2 - 可被-CH = CH-代替，并且氢可以被卤素取代; 环A1和环A2各自独立地为反式-1,4-亚环己基或1,4-亚苯基，条件是在这些环中，氢可以被卤素代替，并且在环是反式-1,4-亚环己基的情况下 ，-CH 2 - 可以被-O-取代，-CH 2 CH-可以被-CH = C - 取代; 并且Z 1和Z 2各自独立地为单键-COO-，-OCO-，-OCH 2 - ， - CH 2 O-或-CH 2 CH 2 - ，条件是在式（a-3）中，在环A2为反式 - 1,4-亚环己基，Z2为单键，-COO-，-OCO-，-OCH2-或-CH2O-，在Ra为-C3H7的情况下，Rb为-OC2H5，Z2为单键，环， A2是反式-1,4-亚环己基，1,3-二恶烷-2,5-二基，2-氟-1,4-亚苯基，3-氟-1,4-亚苯基，2-氟-3-氯 - 1,4-亚苯基，2-氯-3-氟-3,4-亚苯基或2,3-二氯-1,4-亚苯基，在式（a-4）中，在环A 1为反式 - 1,4-亚环己基，Z1是单键，-COO-，-OCO-，-OCH2-或-CH2O-。