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1.Quinoline derivatives, their preparation, their use, and medicaments comprising them 审中-公开
标题翻译: 喹啉衍生物,其制备方法,用途以及包含它们的药物公开(公告)号:US20080056987A1
公开(公告)日:2008-03-06
申请号:US11765683
申请日:2007-06-20
申请人: Olaf Prien , Knut Eis , Duy Nguyen , Christoph Huwe , Wolfgang Schwede , Judith Guenther , Dieter Zopf
发明人: Olaf Prien , Knut Eis , Duy Nguyen , Christoph Huwe , Wolfgang Schwede , Judith Guenther , Dieter Zopf
IPC分类号: A61K51/00 , A61K31/47 , A61P25/00 , A61P9/00 , C07D295/00 , C12Q1/00 , C12N9/99 , C07D215/00 , A61P43/00 , A61K31/5377
CPC分类号: C07D513/04 , C07D495/04
摘要: The present invention relates to a quinoline derivative having the general formula (A) in which R1, R2, W, X, Y and Z are indicated in the description and the claims, the use of the compounds of the general formula (A) for the treatment of various disorders, and the preparation of compounds of the general formula (A).
摘要翻译: 本发明涉及具有通式(A)的喹啉衍生物,其中R 1,R 2,W,X,Y和Z在说明书中表示, 权利要求书,通式(A)的化合物用于各种病症的治疗,以及制备通式(A)的化合物。
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2.Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs 有权
标题翻译: 磺酰亚胺取代的嘧啶,其制备方法和用途作为药物公开(公告)号:US20070232632A1
公开(公告)日:2007-10-04
申请号:US11642961
申请日:2006-12-21
申请人: Ulrich Lucking , Duy Nguyen , Arne Von Bonin , Oliver Von Ahsen , Martin Kruger , Hans Briem , Georg Kettschau , Olaf Prien , Anne Mengel , Krolikiewicz Konrad , Ulf Boemer , Ulrich Bothe , Ingo Hartung
发明人: Ulrich Lucking , Duy Nguyen , Arne Von Bonin , Oliver Von Ahsen , Martin Kruger , Hans Briem , Georg Kettschau , Olaf Prien , Anne Mengel , Krolikiewicz Konrad , Ulf Boemer , Ulrich Bothe , Ingo Hartung
IPC分类号: A61K31/506 , C07D417/02
CPC分类号: C07D239/28 , C07D239/47 , C07D239/48 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/04 , C07D409/14 , C07D413/04 , C07D417/04
摘要: The invention relates to sulfoximine-substituted pyrimidines of the general formula I processes for the preparation thereof and their use as drugs.
摘要翻译: 本发明涉及通式I的亚磺酰亚胺取代嘧啶,其制备方法及其作为药物的用途。
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3.Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs 有权
标题翻译: 磺酰亚胺取代的嘧啶,其制备方法和用途作为药物公开(公告)号:US07825128B2
公开(公告)日:2010-11-02
申请号:US11642961
申请日:2006-12-21
申请人: Ulrich Lücking , Duy Nguyen , Arne Von Bonin , Oliver Von Ahsen , Martin Krüger , Hans Briem , Georg Kettschau , Olaf Prien , Anne Mengel , Krolikiewicz Konrad , Ulf Boemer , Ulrich Bothe , Ingo Hartung
发明人: Ulrich Lücking , Duy Nguyen , Arne Von Bonin , Oliver Von Ahsen , Martin Krüger , Hans Briem , Georg Kettschau , Olaf Prien , Anne Mengel , Krolikiewicz Konrad , Ulf Boemer , Ulrich Bothe , Ingo Hartung
IPC分类号: C07D239/47 , C07D239/48 , C07D403/04 , C07D403/14 , C07D409/04 , C07D409/14 , C07D401/04 , C07D405/04 , C07D413/04 , C07D417/04 , A61K31/505 , A61K31/506 , A61P19/02 , A61P35/00
CPC分类号: C07D239/28 , C07D239/47 , C07D239/48 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/04 , C07D409/14 , C07D413/04 , C07D417/04
摘要: The invention relates to sulfoximine-substituted pyrimidines of the general formula I processes for the preparation thereof and their use as drugs.
摘要翻译: 本发明涉及通式I的亚磺酰亚胺取代嘧啶,其制备方法及其作为药物的用途。
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公开(公告)号:US20060074084A1
公开(公告)日:2006-04-06
申请号:US11233533
申请日:2005-09-23
申请人: Duy Nguyen , Anne Mengel , Martin Fritsch , Gernor Langer , Ulf Boemer , Knut Eis , Bernd Menzenbach , Bernd Buchmann , Seock-Kyu Khim
发明人: Duy Nguyen , Anne Mengel , Martin Fritsch , Gernor Langer , Ulf Boemer , Knut Eis , Bernd Menzenbach , Bernd Buchmann , Seock-Kyu Khim
IPC分类号: A61K31/5377 , A61K31/496 , A61K31/454 , A61K31/4439 , A61K31/405 , C07D413/02 , C07D405/02 , C07D403/02
CPC分类号: C07D405/12 , C07D209/42 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/12 , C07D417/12
摘要: The invention relates to compounds of general formula I as well as their production and use as a medication.
摘要翻译: 本发明涉及通式I的化合物及其作为药物的生产和用途。
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5.Tetrahydronaphthalene derivatives, processes for their preparation and their use as antiinflammatory agents 审中-公开
标题翻译: 四氢萘衍生物,其制备方法及其作为抗炎剂的用途公开(公告)号:US20070129359A1
公开(公告)日:2007-06-07
申请号:US11414556
申请日:2006-05-01
申请人: Christoph Huwe , Werner Skuballa , Duy Nguyen , Heike Schaecke , Wheeseong Lee
发明人: Christoph Huwe , Werner Skuballa , Duy Nguyen , Heike Schaecke , Wheeseong Lee
IPC分类号: A61K31/538 , A61K31/498 , A61K31/4745 , A61K31/4704 , A61K31/404 , A61K31/4035
CPC分类号: C07C233/74 , C07C217/74 , C07C275/28 , C07C311/20 , C07C2602/10
摘要: The invention relates to multiply substituted tetrahydronaphthalene derivatives of the formula (I) processes for their preparation and their use as anti-inflammatory agents.
摘要翻译: 本发明涉及式(I)的多取代四氢萘衍生物,其制备方法及其作为抗炎剂的用途。
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6.2-arylthiazole-4-carboxamide derivatives, their preparation and use as pharmaceuticals 有权
标题翻译: 2-芳基噻唑-4-甲酰胺衍生物,它们的制备和用作药物公开(公告)号:US08163739B2
公开(公告)日:2012-04-24
申请号:US12331775
申请日:2008-12-10
申请人: Ulrich Bothe , Arne Von Bonin , Duy Nguyen , Ulf Bomer , Judith Guenther
发明人: Ulrich Bothe , Arne Von Bonin , Duy Nguyen , Ulf Bomer , Judith Guenther
IPC分类号: A61K31/535 , A61K31/425
CPC分类号: C07D277/56 , C07D417/04 , C07D417/12 , C07D417/14 , C07D495/04
摘要: The present invention relates to 2-arylthiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof
摘要翻译: 本发明涉及式(I)的2-芳基噻唑-4-甲酰胺衍生物,其作为治疗各种病症的药物的用途及其制备方法
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7.2-substituted thiazole-4-carboxamide derivatives, their preparation and use as pharmaceuticals 有权
标题翻译: 2-取代的噻唑-4-甲酰胺衍生物,其制备和用作药物公开(公告)号:US07897626B2
公开(公告)日:2011-03-01
申请号:US12330696
申请日:2008-12-09
申请人: Ulrich Bothe , Arne Von Bonin , Duy Nguyen , Ulf Bömer , Judith Guenther
发明人: Ulrich Bothe , Arne Von Bonin , Duy Nguyen , Ulf Bömer , Judith Guenther
IPC分类号: A61K31/4155 , A61K31/426 , C07D277/24
CPC分类号: C07D417/14 , C07D417/04
摘要: The present invention relates to 2-substituted thiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof
摘要翻译: 本发明涉及式(I)的2-取代噻唑-4-甲酰胺衍生物,其用作治疗各种疾病的药物的用途及其制备方法
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8.NOVEL 2-HETARYLTHIAZOLE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS PHARMACEUTICALS 有权
标题翻译: 新型2-炔丙基-4-羧酰胺衍生物,其制备和用作药物公开(公告)号:US20090203715A1
公开(公告)日:2009-08-13
申请号:US12331028
申请日:2008-12-09
申请人: Ulrich Bothe , Arne Von Bonin , Duy Nguyen , Ulf Bomer , Judith Guenther
发明人: Ulrich Bothe , Arne Von Bonin , Duy Nguyen , Ulf Bomer , Judith Guenther
IPC分类号: A61K31/4965 , C07D417/04 , A61K31/4439 , C07D417/14 , A61K31/444 , A61K31/4365 , C07D471/02
CPC分类号: C07D417/04 , C07D417/14 , C07D495/02
摘要: The present invention relates to 2-hetarylthiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof
摘要翻译: 本发明涉及式(I)的2-噻吨基噻唑-4-甲酰胺衍生物,其作为治疗各种病症的药物的用途及其制备方法
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9.NOVEL 2-SUBSTITUTED TIAZOLE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS PHARMACEUTICALS 有权
标题翻译: 新型2-取代的噻唑-4-羧酰胺衍生物,其制备和用作药物公开(公告)号:US20090149517A1
公开(公告)日:2009-06-11
申请号:US12330696
申请日:2008-12-09
申请人: Ulrich Bothe , Ame Von Bonin , Duy Nguyen , Ulf Bomer , Judith Guenther
发明人: Ulrich Bothe , Ame Von Bonin , Duy Nguyen , Ulf Bomer , Judith Guenther
IPC分类号: A61K31/427 , C07D417/14
CPC分类号: C07D417/14 , C07D417/04
摘要: The present invention relates to 2-substituted thiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof
摘要翻译: 本发明涉及式(I)的2-取代噻唑-4-甲酰胺衍生物,其用作治疗各种疾病的药物的用途及其制备方法
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10.2-hetarylthiazole-4-carboxamide derivatives, their preparation and use as pharmaceuticals 有权
标题翻译: 2-萘基噻唑-4-甲酰胺衍生物,其制备和用作药物公开(公告)号:US08148411B2
公开(公告)日:2012-04-03
申请号:US12331028
申请日:2008-12-09
申请人: Ulrich Bothe , Arne Von Bonin , Duy Nguyen , Ulf Bomer , Judith Guenther
发明人: Ulrich Bothe , Arne Von Bonin , Duy Nguyen , Ulf Bomer , Judith Guenther
IPC分类号: A61K31/4155 , A61K31/426 , C07D277/24
CPC分类号: C07D417/04 , C07D417/14 , C07D495/02
摘要: The present invention relates to 2-hetarylthiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof
摘要翻译: 本发明涉及式(I)的2-噻吨基噻唑-4-甲酰胺衍生物,其作为治疗各种病症的药物的用途及其制备方法
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