Peptide derivatization method to increase fragmentation information from MS/MS spectra
    2.
    发明授权
    Peptide derivatization method to increase fragmentation information from MS/MS spectra 有权
    肽衍生化方法从MS / MS谱增加碎片信息

    公开(公告)号:US07838303B2

    公开(公告)日:2010-11-23

    申请号:US11494383

    申请日:2006-07-27

    IPC分类号: G01N24/00

    摘要: A method of facilitating analysis of a peptide in a mass spectrometer comprising derivatizing the C-terminus of the peptide with an amino acid residue via a reaction with a carbodiimide reagent, yielding a derivative peptide, ionizing the derivative peptide with a double charge, and fragmenting the ionized derivative peptide in a mass spectrometry system, wherein binary fragments of the ionized derivative each include a charge, facilitating sequence analysis of the peptide.

    摘要翻译: 一种促进质谱分析肽的方法,包括通过与碳二亚胺试剂的反应将肽的C末端与氨基酸残基衍生化,产生衍生肽,以双电荷离子化衍生肽,并将其断裂 质谱系统中的离子化衍生肽,其中电离衍生物的二元片段各自包含电荷,便于肽的序列分析。

    Super alloy ionization chamber for reactive samples
    3.
    发明授权
    Super alloy ionization chamber for reactive samples 有权
    超合金电离室用于反应性样品

    公开(公告)号:US06974956B2

    公开(公告)日:2005-12-13

    申请号:US10810396

    申请日:2004-03-25

    CPC分类号: H01J49/10 H01J37/08

    摘要: The present invention relates to an ionization source having a chamber for ionizing a sample. The ionization chamber has surfaces to reduce the overall interaction with reactive samples. The inner surface walls of the ionization chamber or the ionization chamber may be formed from an inert super alloy. For instance, Inconel™ 625, Inconel™ 601 or Hastelloy® may comprise the ionization chamber or the surface walls of the ionization chamber. The invention also includes a method for reducing the interaction of a reactive analyte with an ion source.

    摘要翻译: 本发明涉及一种具有用于离子化样品的室的电离源。 电离室具有减少与反应性样品的整体相互作用的表面。 电离室或电离室的内表面壁可以由惰性超级合金形成。 例如,Inconel TM 625,Inconel TM 601或Hastelloy可以包括电离室或电离室的表面壁。 本发明还包括减少反应性分析物与离子源的相互作用的方法。

    Process for producing alpha-picoline
    5.
    发明授权
    Process for producing alpha-picoline 失效
    生产α-甲基吡啶的方法

    公开(公告)号:US4388461A

    公开(公告)日:1983-06-14

    申请号:US384360

    申请日:1982-06-02

    CPC分类号: C07D213/06 C07D213/08

    摘要: Alpha-picoline is produced by the ammoniation of phenol over a zeolite having a silica:alumina ratio of at least 12 and a constraint index of 1 to 12. The preferred zeolite is ZSM-5. Aniline is produced as a co-product and the alpha-picoline may be separated by distillation or extraction.

    摘要翻译: α-甲基吡啶通过苯酚的氨化在二氧化硅:氧化铝比至少为12且约束指数为1至12的沸石上生成。优选的沸石是ZSM-5。 生产苯胺作为副产物,α-甲基吡啶可以通过蒸馏或萃取分离。

    Exploratory visualization of protein complexes by molecular weight
    6.
    发明申请
    Exploratory visualization of protein complexes by molecular weight 有权
    蛋白复合物的分子量的探索可视化

    公开(公告)号:US20090192719A1

    公开(公告)日:2009-07-30

    申请号:US12011347

    申请日:2008-01-25

    IPC分类号: G01N33/48

    CPC分类号: G06F19/26 G06F19/18

    摘要: Methods, user interfaces, systems and computer readable media for visualizing data to facilitate analysis of the data. Mass data values are provided for a sample having been separated into portions according to a first characteristic of the sample, the slices having been processed to provide the mass data values of members of the sample occurring in the portions. A plot of the mass data values is displayed on a first axis versus the portions on a second axis of the plot. A mass data value of a member may be selected on the plot, and all mass data values occurring in the portion in which the selected mass data value is located are displayed using first visual indicators that are visibly distinct from visual indicators used to display data values occurring outside of the portion in which the selected data value is located.

    摘要翻译: 用于可视化数据以方便数据分析的方法,用户界面,系统和计算机可读介质。 为根据样品的第一特性分离成部分的样品提供质量数据值,已经处理了切片以提供部分中出现的样品的质量数据值。 质量数据值的曲线显示在第一轴上,而不是绘图的第二个轴上的部分。 可以在绘图上选择成员的质量数据值,并且使用与用于显示数据值的视觉指示器明显不同的第一视觉指示器来显示出现在选择的质量数据值所在部分中的所有质量数据值 发生在所选数据值所在部分之外。

    Super alloy ionization chamber for reactive samples
    7.
    发明授权
    Super alloy ionization chamber for reactive samples 失效
    超合金电离室用于反应性样品

    公开(公告)号:US07304299B2

    公开(公告)日:2007-12-04

    申请号:US11590069

    申请日:2006-10-30

    IPC分类号: H01J27/00

    CPC分类号: H01J49/10 H01J37/08

    摘要: The present invention relates to an ionization source having a chamber for ionizing a sample. The ionization chamber has surfaces to reduce the overall interaction with reactive samples. The inner surface walls of the ionization chamber or the ionization chamber may be formed from an inert super alloy. For instance, Inconel™ 625, Inconel™ 601 or Hastelloy® may comprise the ionization chamber or the surface walls of the ionization chamber. The invention also includes a method for reducing the interaction of a reactive analyte with an ion source.

    摘要翻译: 本发明涉及一种具有用于离子化样品的室的电离源。 电离室具有减少与反应性样品的整体相互作用的表面。 电离室或电离室的内表面壁可以由惰性超级合金形成。 例如,Inconel TM 625,Inconel TM 601或Hastelloy可以包括电离室或电离室的表面壁。 本发明还包括减少反应性分析物与离子源的相互作用的方法。

    Super alloy ionization chamber for reactive samples
    8.
    发明授权
    Super alloy ionization chamber for reactive samples 有权
    超合金电离室用于反应性样品

    公开(公告)号:US06765215B2

    公开(公告)日:2004-07-20

    申请号:US09894204

    申请日:2001-06-28

    IPC分类号: H01J2700

    CPC分类号: H01J49/10 H01J37/08

    摘要: The present invention relates to an ionization source having a chamber for ionizing a sample. The ionization chamber has surfaces to reduce the overall interaction with reactive samples. The inner surface walls of the ionization chamber or the ionization chamber may be formed from an inert super alloy. For instance, Inconel™ 625, Inconel™ 601 or Hastelloy®) may comprise the ionization chamber or the surface walls of the ionization chamber. The invention also includes a method for reducing the interaction of a reactive analyte with an ion source.

    摘要翻译: 本发明涉及一种具有用于离子化样品的室的电离源。 电离室具有减少与反应性样品的整体相互作用的表面。 电离室或电离室的内表面壁可以由惰性超级合金形成。 例如,Inconel TM 625,Inconel TM 601或Hastelloy)可以包括电离室或电离室的表面壁。 本发明还包括减少反应性分析物与离子源的相互作用的方法。

    Process for making alkyl pyrazines
    9.
    发明授权
    Process for making alkyl pyrazines 失效
    制备烷基吡嗪的方法

    公开(公告)号:US4855431A

    公开(公告)日:1989-08-08

    申请号:US457806

    申请日:1983-01-13

    IPC分类号: C07D241/12

    CPC分类号: C07D241/12

    摘要: The invention deals with a process for making a pyrazine from an aminoalkanol by passing it over a crystalline aluminosilicate zeolite having a silica to alumina ratio of at least 12 and a constraint index of 1 to 12 under conditions to dehydrate, dehydrogenate and cyclize it.

    摘要翻译: 本发明涉及一种通过使二氧化硅与氧化铝之比至少为12且约束指数为1至12的结晶硅铝酸盐沸石在脱水,脱氢和使其环化的条件下将其从氨基烷醇制备吡嗪的方法。

    Exploratory visualization of protein complexes by molecular weight
    10.
    发明授权
    Exploratory visualization of protein complexes by molecular weight 有权
    蛋白复合物的分子量的探索可视化

    公开(公告)号:US07930108B2

    公开(公告)日:2011-04-19

    申请号:US12011347

    申请日:2008-01-25

    IPC分类号: G06F19/00

    CPC分类号: G06F19/26 G06F19/18

    摘要: Methods, user interfaces, systems and computer readable media for visualizing data to facilitate analysis of the data. Mass data values are provided for a sample having been separated into portions according to a first characteristic of the sample, the slices having been processed to provide the mass data values of members of the sample occurring in the portions. A plot of the mass data values is displayed on a first axis versus the portions on a second axis of the plot. A mass data value of a member may be selected on the plot, and all mass data values occurring in the portion in which the selected mass data value is located are displayed using first visual indicators that are visibly distinct from visual indicators used to display data values occurring outside of the portion in which the selected data value is located.

    摘要翻译: 用于可视化数据以方便数据分析的方法,用户界面,系统和计算机可读介质。 为根据样品的第一特性分离成部分的样品提供质量数据值,已经处理了切片以提供部分中出现的样品的质量数据值。 质量数据值的曲线显示在第一轴上,而不是绘图的第二个轴上的部分。 可以在绘图上选择成员的质量数据值,并且使用与用于显示数据值的视觉指示器明显不同的第一视觉指示器来显示出现在选择的质量数据值所在部分中的所有质量数据值 发生在所选数据值所在部分之外。