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    METHODS AND APPARATUSES FOR PREDICTING THE EFFECTS OF ERYTHROPOIESIS STIMULATING AGENTS, AND FOR DETERMINING A DOSE TO BE ADMINISTERED
    9.
    发明申请
    METHODS AND APPARATUSES FOR PREDICTING THE EFFECTS OF ERYTHROPOIESIS STIMULATING AGENTS, AND FOR DETERMINING A DOSE TO BE ADMINISTERED 审中-公开
    用于预测红细胞生成刺激剂的作用和用于测定待给药的剂量的方法和装置

    公开(公告)号：US20130052136A1

    公开(公告)日：2013-02-28

    申请号：US13636897

    申请日：2011-03-21

    申请人： Paul Chamney ,  Ulrich Moissl ,  Peter Wabel ,  Sebastian Wieskotten ,  Volker Nier

    发明人： Paul Chamney ,  Ulrich Moissl ,  Peter Wabel ,  Sebastian Wieskotten ,  Volker Nier

    IPC分类号： G01N33/49 ,  A61B5/053 ,  G01N33/493 ,  A61K49/00

    CPC分类号： G01N33/721 ,  G01N33/726 ,  G01N2800/52

    摘要： The present invention relates to a method for predicting the concentration or the mass of hemoglobin or an approximation thereof, respectively, in a body fluid and/or an extracorporeal sample thereof of a patient at a later, second point of time, the patient having theoretically or in reality been administered a certain dose of an erythropoiesis stimulating agent at an earlier, first point of time. It relates further to a method for determining the dose of an erythropoiesis stimulating agent to be administered to a patient, to a method for determining whether a patient is affected by circumstances leading to the loss of hemoglobin, to corresponding devices and to an erythropoiesis stimulating medicament for use in the treatment of anemia.

    摘要翻译： 本发明涉及一种用于在稍后的第二时间点分别预测患者的体液和/或其体外样品中血红蛋白的浓度或质量或其近似值的方法，患者理论上 或者实际上是在较早的第一时间点给予一定剂量的红细胞生成刺激剂。 本发明还涉及用于确定要给予患者的红细胞生成刺激剂的剂量的方法，用于确定患者是否受到导致血红蛋白丧失的情况的影响的方法，对相应的装置和促红细胞生成药物 用于治疗贫血。

    Method for determining concentration; a dialyser
    10.
    发明申请
    Method for determining concentration; a dialyser 有权
    浓度测定方法 透析器

    公开(公告)号：US20050236330A1

    公开(公告)日：2005-10-27

    申请号：US11148172

    申请日：2005-06-09

    申请人： Volker Nier ,  Matthias Kraemer

    发明人： Volker Nier ,  Matthias Kraemer

    IPC分类号： A61M1/14 ,  A61M1/16 ,  A61M1/34 ,  A61M1/36 ,  G01N33/84 ,  C02F1/44

    CPC分类号： G01N33/84 ,  A61M1/16 ,  A61M1/1609 ,  A61M1/1617 ,  A61M1/3437 ,  A61M1/3609 ,  A61M1/3675 ,  A61M2205/18 ,  A61M2205/50 ,  A61M2230/20 ,  G01N2800/04

    摘要： A dialyser having a haemo-dialyser and/or a haemo-filter and an extra-corporal blood circulation with which a device for the adding of citrate to the blood is connected upstream and a device for the adding of a substitution solution containing ions to the blood is connected downstream of the haemo-dialyser and/or of the haemo-filter. Ion concentration in the dialysate downstream of the haemo-dialyser and/or of the haemo-filter is detected with respect to the direction of flow of the dialysate. The concentration of the ion, atom or molecule to be determined is reliably ascertained by preventing the complexing of the ion, atom or molecule, at least during the determination of the concentration, by the addition or withdrawal of a substance.

    摘要翻译： 具有血液透析器和/或血液过滤器和体外血液循环的透析器，用于向血液中加入柠檬酸盐的装置与上游连接，以及用于将含有离子的置换溶液添加到 血液连接在血液透析器和/或血液过滤器的下游。 相对于透析液的流动方向检测透析器和/或血液滤过器下游的透析液中的离子浓度。 要确定的离子，原子或分子的浓度通过至少在浓度测定期间通过物质的添加或取出来防止离子，原子或分子的络合而被可靠地确定。