Aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and
carbothioamides having antiarrhythmic activity
    1.
    发明授权
    Aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and carbothioamides having antiarrhythmic activity 失效
    丙烯酰氧基-N-(氨基烷基)-1-吡咯烷和哌啶甲酰胺和具有抗心律失常活性的硫代酰胺

    公开(公告)号:US4547514A

    公开(公告)日:1985-10-15

    申请号:US557885

    申请日:1983-12-05

    摘要: Pharmaceutical compositions comprised of aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and carbothioamides are provided of the formula: ##STR1## wherein Ar is selected from the group consisting of 1-naphthyl, 2-naphthyl, 2,3-dihydro-1H-inden-4-yl, 2,3-dihydro-1H-inden-5-yl, phenyl, substituted phenyl wherein the substituents are selected from lower alkyl of from 1 to 8 carbon atoms, lower alkyloxy of from 1 to 8 carbon atoms, halogen and trifluoromethyl; m and n are 1 or 2 but are never 2 at the same time; p is 1, 2, 3 or 4; R is selected from hydrogen or lower alkyl of from 1 to 3 carbon atoms; R.sup.1 and R.sup.2 are selected from hydrogen, lower alkyl of from 1 to 8 carbon atoms, phenyl, phenyl lower alkyl of from 7 to 9 carbon atoms, and cycloalkyl of from 3 to 8 carbon atoms, and R.sup.1 and R.sup.2 taken together with the adjacent atom may form a heterocyclic residue selected from 4-morpholino, 1-pyrrolidino, 1-piperidino, 1-piperazino and 4-lower alkyl piperazin-1-yl; X is oxygen or sulfur; and the pharmaceutically acceptable acid addition salts thereof having antiarrhythmic activity.

    摘要翻译: 由芳氧基-N-(氨基烷基)-1-吡咯烷和哌啶甲酰胺和硫代酰胺组成的药物组合物由下式提供:其中Ar选自1-萘基,2-萘基, 二氢-1H-茚-4-基,2,3-二氢-1H-茚-5-基,苯基,取代苯基,其中取代基选自1至8个碳原子的低级烷基,低级烷氧基为1至 8个碳原子,卤素和三氟甲基; m和n是1或2,但从不同时2; p为1,2,3或4; R选自氢或1至3个碳原子的低级烷基; R1和R2选自氢,1至8个碳原子的低级烷基,苯基,7至9个碳原子的苯基低级烷基和3至8个碳原子的环烷基,以及R1和R2与相邻的 原子可以形成选自4-吗啉代,1-吡咯烷子基,1-哌啶子基,1-哌嗪基和4-低级烷基哌嗪-1-基的杂环残基; X是氧或硫; 及其药学上可接受的酸加成盐具有抗心律不齐活性。

    Speed Sensor System and Mounting Configuration for Locomotive Traction Motors
    2.
    发明申请
    Speed Sensor System and Mounting Configuration for Locomotive Traction Motors 审中-公开
    机车牵引电机的速度传感器系统和安装配置

    公开(公告)号:US20130300262A1

    公开(公告)日:2013-11-14

    申请号:US13467345

    申请日:2012-05-09

    申请人: William L. Smith

    发明人: William L. Smith

    IPC分类号: H02K11/00

    摘要: A speed sensor system for a locomotive traction motor of the type having a motor frame head adjacent each wheel truck, including a mounting bracket, attachable to the frame head at a prescribed distance from an axis of rotation of the motor and a sensor support portion extending from the inner surface through the ventilation opening and having a hollow tubular portion at the end for releasably receiving and positioning a separate sensor assembly in such a manner that the sensor itself is precisely positioned with respect to the armature gear surface of the traction motor.

    摘要翻译: 一种用于机车牵引电动机的速度传感器系统,其具有与每个车轮车相邻的电动机框架头部,包括安装支架,其能够以与电动机的旋转轴线规定的距离相连接到框架头部;以及传感器支撑部分,其延伸 从内表面通过通风口并且在端部具有中空的管状部分,以可释放地接收和定位单独的传感器组件,使得传感器本身相对于牵引电动机的电枢齿轮表面精确定位。

    System and method for providing a single telephone number for use with a plurality of telephone handsets
    3.
    发明授权
    System and method for providing a single telephone number for use with a plurality of telephone handsets 有权
    用于提供与多个电话手机一起使用的单个电话号码的系统和方法

    公开(公告)号:US08532679B2

    公开(公告)日:2013-09-10

    申请号:US12614781

    申请日:2009-11-09

    IPC分类号: H04W4/00

    摘要: Systems and methods providing integrated voice and data services utilizing wired cordless access with unlicensed/unregulated connectivity sources and wireless access with licensed/regulated connectivity sources. A single telephone directory number is assigned for use with both a mobile wireless telephone and for use with a cordless wired Internet Protocol (IP) telephone. The mobile wireless telephone operates via a conventional licensed spectrum wireless network, and the IP telephone operates over voice over Internet protocol (VoIP) over a broadband packet data network service. Incoming calls simultaneously ring the user's mobile wireless telephone and IP telephone. The user may be provided a personal voice mailbox that may be accessed from their mobile wireless telephone or from their IP telephone. The user may be provided a single services bill associated with use of both telephones.

    摘要翻译: 系统和方法提供集成的语音和数据服务,利用具有未许可/不受管制连接源的有线无绳接入以及具有许可/调节连接源的无线接入。 分配单个电话号码簿号码以用于移动无线电话并用于无绳有线因特网协议(IP)电话。 移动无线电话通过常规许可频谱无线网络操作,并且IP电话通过宽带分组数据网络服务在互联网协议语音(VoIP)上运行。 来电同时振铃用户的移动无线电话和IP电话。 可以向用户提供可以从他们的移动无线电话或从其IP电话访问的个人语音信箱。 可以向用户提供与使用两个电话相关联的单个服务账单。

    METHOD OF TREATING A SUBSTRATE WITH STABLE BLEACHES WITH COLORING AGENTS
    5.
    发明申请
    METHOD OF TREATING A SUBSTRATE WITH STABLE BLEACHES WITH COLORING AGENTS 有权
    用着色剂处理具有稳定漂白剂的基材的方法

    公开(公告)号:US20120009279A1

    公开(公告)日:2012-01-12

    申请号:US13237817

    申请日:2011-09-20

    摘要: The invention provides an aqueous bleaching solution for substrate treatment comprising a source of oxidant and a suspended polymer matrix having a plurality of optically functional particles associated with one or more copolymers present in the polymer matrix. The plurality of optically functional particles are associated with the copolymer during polymerization of at least one hydrophobic and at least one hydrophilic monomer so as to form a polymer matrix useful to impart an aqueous bleaching solution with optically functional properties providing a benefit to the solutions during storage, use and application to substrates for treatment. In accordance with various embodiments of the invention, the suspended polymer matrix forms a substantially stable dispersion of the optically functional particles in the aqueous bleaching solution, and provides compositions, methods and kits for employing aqueous bleaching solutions having optically functional properties that are maintained over substantially long storage times.

    摘要翻译: 本发明提供了用于底物处理的水性漂白溶液,其包括氧化剂源和悬浮聚合物基质,其具有与存在于聚合物基质中的一种或多种共聚物相关联的多个光学功能性颗粒。 在至少一种疏水性和至少一种亲水性单体的聚合过程中,多种光学功能性颗粒与共聚物相关联,以便形成聚合物基质,其可用于赋予具有光学功能性质的水性漂白溶液以提供储存期间的溶液的益处 ,使用和应用于底物进行治疗。 根据本发明的各种实施方案,悬浮聚合物基质形成水性漂白溶液中的光学功能性颗粒的基本上稳定的分散体,并且提供了使用具有光学功能特性的水性漂白溶液的组合物,方法和试剂盒, 长存储时间。