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公开(公告)号：US20080241158A1
公开(公告)日：2008-10-02
申请号：US11896125
申请日：2007-08-29
申请人： Preeti G. Lal , Richard C. Graul , April J.A. Hafalia , Narinder K. Chawla , Michael B. Thornton , Danniel B. Nguyen , Yan Lu , Ameena R. Gandhi , Chandra S. Arvizu , Deborah A. Kallick , Mariah R. Baughn , Jayalaxmi Ramkumar , Catherine M. Tribouley , Ernestine A. Lee , Li Ding , Neil Burford , Monique G. Yao , Junming Yang , Jennifer A. Griffin
发明人： Preeti G. Lal , Richard C. Graul , April J.A. Hafalia , Narinder K. Chawla , Michael B. Thornton , Danniel B. Nguyen , Yan Lu , Ameena R. Gandhi , Chandra S. Arvizu , Deborah A. Kallick , Mariah R. Baughn , Jayalaxmi Ramkumar , Catherine M. Tribouley , Ernestine A. Lee , Li Ding , Neil Burford , Monique G. Yao , Junming Yang , Jennifer A. Griffin
IPC分类号： A61K39/395 , C07K14/00 , C07H21/00 , C12N1/21 , C12P21/00 , C07K16/00 , C07K1/14 , A61P35/00 , A61P25/00 , A61P9/00 , G01N33/00 , G01N33/68 , C12Q1/68 , A61K38/16 , G01N33/53
CPC分类号： C07K14/705 , A61K38/00 , G01N2333/4719 , Y10T436/143333
摘要： The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
摘要翻译： 本发明提供鉴定和编码GCREC的人G-蛋白偶联受体（GCREC）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与GCREC异常表达相关的疾病的方法。
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公开(公告)号：US06927056B2
公开(公告)日：2005-08-09
申请号：US10363937
申请日：2001-09-06
申请人： Stephen Todd , Angelo M. Delegeane , Ameena R. Gandhi , Danniel B. Nguyen , April J. A. Hafalia , Liam Kearney , Yan Lu , Ernestine A. Lee , Narinder K. Chawla , Debopriya Das , Chandra S. Arvizu , Monique G. Yao , Deborah A. Kallick , Vicki S. Elliott , Li Ding , Henry Yue , Roopa M. Reddy , Dyung Aina M. Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine M. Tribouley , Neil Burford , Mariah R. Baughn , Preeti G. Lal , Mark L. Borowsky , Farrah A. Khan , Rajagopal Gururajan , Y. Tom Tang , Janice K. Au-Young , Bridget A. Warren , Roberto Hernandez , Brendan M. Duggan
发明人： Stephen Todd , Angelo M. Delegeane , Ameena R. Gandhi , Danniel B. Nguyen , April J. A. Hafalia , Liam Kearney , Yan Lu , Ernestine A. Lee , Narinder K. Chawla , Debopriya Das , Chandra S. Arvizu , Monique G. Yao , Deborah A. Kallick , Vicki S. Elliott , Li Ding , Henry Yue , Roopa M. Reddy , Dyung Aina M. Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine M. Tribouley , Neil Burford , Mariah R. Baughn , Preeti G. Lal , Mark L. Borowsky , Farrah A. Khan , Rajagopal Gururajan , Y. Tom Tang , Janice K. Au-Young , Bridget A. Warren , Roberto Hernandez , Brendan M. Duggan
IPC分类号： A01K67/00 , C07H21/04 , C12N9/64 , C12N15/09 , C12P21/06 , C12Q1/68 , C12N1/20 , C12N15/00 , C12N15/63
CPC分类号： C12N9/6421 , A01K2217/05 , A01K2217/075 , C07H21/04 , C12N9/6472 , C12Q1/6837 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , Y02A50/52
摘要： The invention provides a human cysteine proteases and polynucleotides which encode those proteases. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists, as well as methods for diagnosing, treating, or preventing disorders associated with aberrant expression of cysteine proteases.
摘要翻译： 本发明提供编码这些蛋白酶的人半胱氨酸蛋白酶和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂，以及用于诊断，治疗或预防与半胱氨酸蛋白酶异常表达相关的紊乱的方法。
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公开(公告)号：US20130058942A1
公开(公告)日：2013-03-07
申请号：US13562088
申请日：2012-07-30
申请人： Vicki S. Elliott , Reena Khare , Thomas W. Richardson , Joseph P. Marquis , Anita Swarnakar , April J.A. Hafalia , Shanya D. Becha , Narinder K. Chawla-Walia , Mariah R. Baughn , Soo Yeun Lee , Uyen K. Tran , Henry Yue , Danniel B. Nguyen , Michael B. Thornton , Rajagopal Gururajan , Ameena R. Gandhi , Yan Lu , Monique G. Yao , Joana X. Li , Wen Luo , Ernestine A. Lee , Ian J. Forsythe , Craig H. Ison , Amy D. Wilson , Pei Jin
发明人： Vicki S. Elliott , Reena Khare , Thomas W. Richardson , Joseph P. Marquis , Anita Swarnakar , April J.A. Hafalia , Shanya D. Becha , Narinder K. Chawla-Walia , Mariah R. Baughn , Soo Yeun Lee , Uyen K. Tran , Henry Yue , Danniel B. Nguyen , Michael B. Thornton , Rajagopal Gururajan , Ameena R. Gandhi , Yan Lu , Monique G. Yao , Joana X. Li , Wen Luo , Ernestine A. Lee , Ian J. Forsythe , Craig H. Ison , Amy D. Wilson , Pei Jin
CPC分类号： C12N9/16 , C12N9/12 , C12N9/1205 , G01N33/573 , G01N2800/70
摘要： Various embodiments of the invention provide human kinases and phosphatases (KPP) polypeptides and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
摘要翻译： 本发明的各种实施方案提供鉴定和编码KPP的人激酶和磷酸酶（KPP）多肽和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与KPP异常表达相关的紊乱的方法。
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公开(公告)号：US08263378B2
公开(公告)日：2012-09-11
申请号：US12923407
申请日：2010-09-20
申请人： Vicki S. Elliott , Reena Khare , Thomas W. Richardson , Joseph P. Marquis , Anita Swarnakar , April J. A. Hafalia , Shanya D. Becha , Narinder K. Chawla-Walia , Mariah R. Baughn , Soo Yeun Lee , Uyen K. Tran , Henry Yue , Danniel B. Nguyen , Michael B. Thornton , Rajagopal Gururajan , Ameena R. Gandhi , Yan Lu , Monique G. Yao , Joana X. Li , Wen Luo , Ernestine A. Lee , Ian J. Forsythe , Craig H. Ison , Amy D. Wilson , Pei Jin
发明人： Vicki S. Elliott , Reena Khare , Thomas W. Richardson , Joseph P. Marquis , Anita Swarnakar , April J. A. Hafalia , Shanya D. Becha , Narinder K. Chawla-Walia , Mariah R. Baughn , Soo Yeun Lee , Uyen K. Tran , Henry Yue , Danniel B. Nguyen , Michael B. Thornton , Rajagopal Gururajan , Ameena R. Gandhi , Yan Lu , Monique G. Yao , Joana X. Li , Wen Luo , Ernestine A. Lee , Ian J. Forsythe , Craig H. Ison , Amy D. Wilson , Pei Jin
IPC分类号： C12N9/12
CPC分类号： C12N9/16 , C12N9/12 , C12N9/1205 , G01N33/573 , G01N2800/70
摘要： Various embodiments of the invention provide human kinases and phosphatases (KPP) polypeptides and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
摘要翻译： 本发明的各种实施方案提供鉴定和编码KPP的人激酶和磷酸酶（KPP）多肽和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与KPP异常表达相关的紊乱的方法。
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公开(公告)号：US08779106B2
公开(公告)日：2014-07-15
申请号：US13562088
申请日：2012-07-30
申请人： Vicki S. Elliott , Reena Khare , Thomas W. Richardson , Joseph P. Marquis , Anita Swarnakar , April J. A. Hafalia , Shanya D. Becha , Narinder K. Chawla-Walia , Mariah R. Baughn , Soo Yeun Lee , Uyen K. Tran , Henry Yue , Danniel B. Nguyen , Michael B. Thornton , Rajagopal Gururajan , Ameena R. Gandhi , Yan Lu , Monique G. Yao , Joana X. Li , Wen Luo , Ernestine A. Lee , Ian J. Forsythe , Craig H. Ison , Amy D. Wilson , Pei Jin
发明人： Vicki S. Elliott , Reena Khare , Thomas W. Richardson , Joseph P. Marquis , Anita Swarnakar , April J. A. Hafalia , Shanya D. Becha , Narinder K. Chawla-Walia , Mariah R. Baughn , Soo Yeun Lee , Uyen K. Tran , Henry Yue , Danniel B. Nguyen , Michael B. Thornton , Rajagopal Gururajan , Ameena R. Gandhi , Yan Lu , Monique G. Yao , Joana X. Li , Wen Luo , Ernestine A. Lee , Ian J. Forsythe , Craig H. Ison , Amy D. Wilson , Pei Jin
CPC分类号： C12N9/16 , C12N9/12 , C12N9/1205 , G01N33/573 , G01N2800/70
摘要： Various embodiments of the invention provide human kinases and phosphatases (KPP) polypeptides and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
摘要翻译： 本发明的各种实施方案提供鉴定和编码KPP的人激酶和磷酸酶（KPP）多肽和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与KPP异常表达相关的紊乱的方法。
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公开(公告)号：US20120014937A1
公开(公告)日：2012-01-19
申请号：US12923407
申请日：2010-09-20
申请人： Vicki S. Elliott , Reena Khare , Thomas W. Richardson , Joseph P. Marquis , Anita Swarnakar , April J. A. Hafalia , Shanya D. Becha , Narinder K. Chawla-Walia , Mariah R. Baughn , Soo Yeun Lee , Uyen K. Tran , Henry Yue , Danniel B. Nguyen , Michael B. Thornton , Rajagopal Gururajan , Ameena R. Gandhi , Yan Lu , Monique G. Yao , Joana X. Li , Wen Luo , Ernestine A. Lee , Ian J. Forsythe , Craig H. Ison , Amy D. Wilson , Pei Jin
发明人： Vicki S. Elliott , Reena Khare , Thomas W. Richardson , Joseph P. Marquis , Anita Swarnakar , April J. A. Hafalia , Shanya D. Becha , Narinder K. Chawla-Walia , Mariah R. Baughn , Soo Yeun Lee , Uyen K. Tran , Henry Yue , Danniel B. Nguyen , Michael B. Thornton , Rajagopal Gururajan , Ameena R. Gandhi , Yan Lu , Monique G. Yao , Joana X. Li , Wen Luo , Ernestine A. Lee , Ian J. Forsythe , Craig H. Ison , Amy D. Wilson , Pei Jin
IPC分类号： A61K38/45 , A61P37/00 , A61P25/00 , A61P35/00 , C12N5/10 , C12Q1/48 , G01N33/573 , C40B40/10 , C12N1/21 , C12N1/19 , A61P9/00 , C12N9/12
CPC分类号： C12N9/16 , C12N9/12 , C12N9/1205 , G01N33/573 , G01N2800/70
摘要： Various embodiments of the invention provide human kinases and phosphatases (KPP) polypeptides and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
摘要翻译： 本发明的各种实施方案提供鉴定和编码KPP的人激酶和磷酸酶（KPP）多肽和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与KPP异常表达相关的紊乱的方法。
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公开(公告)号：US07829682B1
公开(公告)日：2010-11-09
申请号：US10554917
申请日：2004-03-24
申请人： Vicki S. Elliott , Reena Khare , Thomas W. Richardson , Joseph P. Marquis , Anita Swarnakar , April J. A. Hafalia , Shanya D. Becha , Narinder K. Chawla-Walia , Mariah R. Baughn , Soo Yeun Lee , Uyen K. Tran , Henry Yue , Danniel B. Nguyen , Michael B. Thornton , Rajagopal Gururajan , Ameena R. Gandhi , Yan Lu , Monique G. Yao , Joana X. Li , Wen Luo , Ernestine A. Lee , Ian J. Forsythe , Craig H. Ison , Amy D. Wilson , Pei Jin
发明人： Vicki S. Elliott , Reena Khare , Thomas W. Richardson , Joseph P. Marquis , Anita Swarnakar , April J. A. Hafalia , Shanya D. Becha , Narinder K. Chawla-Walia , Mariah R. Baughn , Soo Yeun Lee , Uyen K. Tran , Henry Yue , Danniel B. Nguyen , Michael B. Thornton , Rajagopal Gururajan , Ameena R. Gandhi , Yan Lu , Monique G. Yao , Joana X. Li , Wen Luo , Ernestine A. Lee , Ian J. Forsythe , Craig H. Ison , Amy D. Wilson , Pei Jin
CPC分类号： C12N9/16 , C12N9/12 , C12N9/1205 , G01N33/573 , G01N2800/70
摘要： Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
摘要翻译： 本发明的各种实施方案提供鉴定和编码KPP的人类激酶和磷酸酶（KPP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与KPP异常表达相关的紊乱的方法。
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