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公开(公告)号:US20080241158A1
公开(公告)日:2008-10-02
申请号:US11896125
申请日:2007-08-29
申请人: Preeti G. Lal , Richard C. Graul , April J.A. Hafalia , Narinder K. Chawla , Michael B. Thornton , Danniel B. Nguyen , Yan Lu , Ameena R. Gandhi , Chandra S. Arvizu , Deborah A. Kallick , Mariah R. Baughn , Jayalaxmi Ramkumar , Catherine M. Tribouley , Ernestine A. Lee , Li Ding , Neil Burford , Monique G. Yao , Junming Yang , Jennifer A. Griffin
发明人: Preeti G. Lal , Richard C. Graul , April J.A. Hafalia , Narinder K. Chawla , Michael B. Thornton , Danniel B. Nguyen , Yan Lu , Ameena R. Gandhi , Chandra S. Arvizu , Deborah A. Kallick , Mariah R. Baughn , Jayalaxmi Ramkumar , Catherine M. Tribouley , Ernestine A. Lee , Li Ding , Neil Burford , Monique G. Yao , Junming Yang , Jennifer A. Griffin
IPC分类号: A61K39/395 , C07K14/00 , C07H21/00 , C12N1/21 , C12P21/00 , C07K16/00 , C07K1/14 , A61P35/00 , A61P25/00 , A61P9/00 , G01N33/00 , G01N33/68 , C12Q1/68 , A61K38/16 , G01N33/53
CPC分类号: C07K14/705 , A61K38/00 , G01N2333/4719 , Y10T436/143333
摘要: The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
摘要翻译: 本发明提供鉴定和编码GCREC的人G-蛋白偶联受体(GCREC)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与GCREC异常表达相关的疾病的方法。
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公开(公告)号:US06927056B2
公开(公告)日:2005-08-09
申请号:US10363937
申请日:2001-09-06
申请人: Stephen Todd , Angelo M. Delegeane , Ameena R. Gandhi , Danniel B. Nguyen , April J. A. Hafalia , Liam Kearney , Yan Lu , Ernestine A. Lee , Narinder K. Chawla , Debopriya Das , Chandra S. Arvizu , Monique G. Yao , Deborah A. Kallick , Vicki S. Elliott , Li Ding , Henry Yue , Roopa M. Reddy , Dyung Aina M. Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine M. Tribouley , Neil Burford , Mariah R. Baughn , Preeti G. Lal , Mark L. Borowsky , Farrah A. Khan , Rajagopal Gururajan , Y. Tom Tang , Janice K. Au-Young , Bridget A. Warren , Roberto Hernandez , Brendan M. Duggan
发明人: Stephen Todd , Angelo M. Delegeane , Ameena R. Gandhi , Danniel B. Nguyen , April J. A. Hafalia , Liam Kearney , Yan Lu , Ernestine A. Lee , Narinder K. Chawla , Debopriya Das , Chandra S. Arvizu , Monique G. Yao , Deborah A. Kallick , Vicki S. Elliott , Li Ding , Henry Yue , Roopa M. Reddy , Dyung Aina M. Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine M. Tribouley , Neil Burford , Mariah R. Baughn , Preeti G. Lal , Mark L. Borowsky , Farrah A. Khan , Rajagopal Gururajan , Y. Tom Tang , Janice K. Au-Young , Bridget A. Warren , Roberto Hernandez , Brendan M. Duggan
IPC分类号: A01K67/00 , C07H21/04 , C12N9/64 , C12N15/09 , C12P21/06 , C12Q1/68 , C12N1/20 , C12N15/00 , C12N15/63
CPC分类号: C12N9/6421 , A01K2217/05 , A01K2217/075 , C07H21/04 , C12N9/6472 , C12Q1/6837 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , Y02A50/52
摘要: The invention provides a human cysteine proteases and polynucleotides which encode those proteases. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists, as well as methods for diagnosing, treating, or preventing disorders associated with aberrant expression of cysteine proteases.
摘要翻译: 本发明提供编码这些蛋白酶的人半胱氨酸蛋白酶和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂,以及用于诊断,治疗或预防与半胱氨酸蛋白酶异常表达相关的紊乱的方法。
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公开(公告)号:US07029897B2
公开(公告)日:2006-04-18
申请号:US10433794
申请日:2001-12-04
申请人: Henry Yue , Li Ding , Preeti G. Lal , Jennifer A. Griffin , Rajagopal Gururajan , Mariah R. Baughn , Craig H. Ison , Jayalaxmi Ramkumar , Catherine M. Tribouley , Anita Swarnakar , Neil Burford , Olga Bandman , Michael Thornton , Farrah A. Khan , Narinder K. Chawla , Danniel B. Nguyen , Vicki S. Elliott , Yuming Xu , Yan Lu , April J. A. Hafalia , Monique G. Yao , Ameena R. Gandhi , Chandra S. Arvizu , Ian J. Forsythe
发明人: Henry Yue , Li Ding , Preeti G. Lal , Jennifer A. Griffin , Rajagopal Gururajan , Mariah R. Baughn , Craig H. Ison , Jayalaxmi Ramkumar , Catherine M. Tribouley , Anita Swarnakar , Neil Burford , Olga Bandman , Michael Thornton , Farrah A. Khan , Narinder K. Chawla , Danniel B. Nguyen , Vicki S. Elliott , Yuming Xu , Yan Lu , April J. A. Hafalia , Monique G. Yao , Ameena R. Gandhi , Chandra S. Arvizu , Ian J. Forsythe
CPC分类号: C12N9/1205 , C07H21/04 , C12N9/16
摘要: The invention provides human kinases and phosphatases (KAP) and polnucleotides which identify and encode KAP. The invention also provides expresson vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KAP.
摘要翻译: 本发明提供鉴定和编码KAP的人激酶和磷酸酶(KAP)和核苷酸。 本发明还提供了表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与KAP的异常表达相关的疾病的方法。
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公开(公告)号:US20100099617A1
公开(公告)日:2010-04-22
申请号:US12585371
申请日:2009-09-14
申请人: Henry Yue , Monique G. Yao , Ameena R. Gandhi , Mariah R. Baughn , Anita Swarnakar , Narinder K. Chawla , Madhusudan M. Sanjanwala , Michael B. Thornton , Vicki S. Elliott , Yan Lu , Kimberly J. Gietzen , Neil Burford , Li Ding , April J. A. Hafalia , Y. Tom Tang , Olga Bandman , Bridget A. Warren , Cynthia D. Honchell , Dyung Aina M. Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti G. Lal , Bao Tran , Craig H. Ison , Brendan M. Duggan , Stephanie K. Sapperstein
发明人: Henry Yue , Monique G. Yao , Ameena R. Gandhi , Mariah R. Baughn , Anita Swarnakar , Narinder K. Chawla , Madhusudan M. Sanjanwala , Michael B. Thornton , Vicki S. Elliott , Yan Lu , Kimberly J. Gietzen , Neil Burford , Li Ding , April J. A. Hafalia , Y. Tom Tang , Olga Bandman , Bridget A. Warren , Cynthia D. Honchell , Dyung Aina M. Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti G. Lal , Bao Tran , Craig H. Ison , Brendan M. Duggan , Stephanie K. Sapperstein
IPC分类号: A61K38/16 , C07K14/00 , A61K38/22 , C07K14/575 , A61P35/00 , A61P29/00 , A61P37/00 , A61P25/00 , A61P9/00 , C12P21/02
CPC分类号: C12N15/1055 , A61K39/3955 , A61K47/64 , A61K47/643 , A61K2039/505 , C07K14/47 , C07K14/4711 , C07K14/4713 , C07K16/18 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/75 , C07K2317/76 , G01N33/5023
摘要: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译: 本发明提供鉴定和编码SECP的人分泌蛋白(SECP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与SECP异常表达相关的疾病的方法。
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公开(公告)号:US06962799B2
公开(公告)日:2005-11-08
申请号:US10362247
申请日:2001-08-20
申请人: Henry Yue , Danniel B. Nguyen , Catherine M. Tribouley , Olga Bandman , Y. Tom Tang , Preeti G. Lal , Narinder K. Chawla , Jennifer L. Policky
发明人: Henry Yue , Danniel B. Nguyen , Catherine M. Tribouley , Olga Bandman , Y. Tom Tang , Preeti G. Lal , Narinder K. Chawla , Jennifer L. Policky
IPC分类号: G01N33/50 , A61K38/00 , A61K45/00 , A61P25/00 , A61P35/00 , A61P37/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号: C07K14/47 , A01K2217/05
摘要: The invention provides human microtubule-associated proteins and tubulins (MICAPTUB) and polynucleotides which identify and encode MICAPTUB. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MICAPTUB.
摘要翻译: 本发明提供了人微管相关蛋白和微管蛋白(MICAPTUB)和识别和编码MICAPTUB的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与MICAPTUB的异常表达相关的疾病的方法。
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公开(公告)号:US07378492B2
公开(公告)日:2008-05-27
申请号:US10504973
申请日:2003-02-18
申请人: Narinder K. Chawla , Henry Yue , Thomas W. Richardson , Joseph P. Marquis , Patricia M. Lehr-Mason , Ann E. Gorvad , Shanya D. Becha , Amy E. Kable , Anita Swarnakar , Pei Jin , Phillip R. Hawkins , David Chien , Jayalaxmi Ramkumar , Uyen K. Tran , April J. A. Hafalia , Mariah R. Baughn , Soo Yeun Lee , Xin Jiang , Alan A. Jackson , Reena Khare , Sean A. Bulloch
发明人: Narinder K. Chawla , Henry Yue , Thomas W. Richardson , Joseph P. Marquis , Patricia M. Lehr-Mason , Ann E. Gorvad , Shanya D. Becha , Amy E. Kable , Anita Swarnakar , Pei Jin , Phillip R. Hawkins , David Chien , Jayalaxmi Ramkumar , Uyen K. Tran , April J. A. Hafalia , Mariah R. Baughn , Soo Yeun Lee , Xin Jiang , Alan A. Jackson , Reena Khare , Sean A. Bulloch
IPC分类号: C07K14/705 , C07K19/00
CPC分类号: C07K14/705 , C07K16/28
摘要: Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and Q polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译: 本发明的各种实施方案提供鉴定和编码REMAP的人受体和膜相关蛋白(REMAP)和Q多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与REMAP异常表达相关的紊乱的方法。
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