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    System and method for using polarized or hyperpolarized contrast agent to perform parallel magnetic resonance imaging of a sample
    1.
    发明申请
    System and method for using polarized or hyperpolarized contrast agent to perform parallel magnetic resonance imaging of a sample 审中-公开
    使用偏振或超极化造影剂进行样品的平行磁共振成像的系统和方法

    公开(公告)号：US20070190663A1

    公开(公告)日：2007-08-16

    申请号：US11504570

    申请日：2006-08-14

    申请人： Ray Lee ,  Georgeann McGunness ,  Glyn Johnson ,  Qun Chen ,  Robert Grossman

    发明人： Ray Lee ,  Georgeann McGunness ,  Glyn Johnson ,  Qun Chen ,  Robert Grossman

    IPC分类号： G01N24/00 ,  A61B5/05

    CPC分类号： G01R33/5601 ,  G01R33/3415 ,  G01R33/3635 ,  G01R33/3642 ,  G01R33/365 ,  G01R33/5611 ,  Y10T436/24

    摘要： A system and method for performing parallel magnetic resonance imaging (“MRI”) with a polarizable or hyperpolarizable contrast agent are provided. The contrast agent may be provided in the form of a gas, a liquid, or a solid. The system may include a phased-array rigid coil with, e.g., a 24-channel phased-array for a receiver and a 2-channel large loop for a transmitter. The phased-array rigid coil can be connected to a low impedance preamplifier for decoupling the strong coupling between two adjacent coils in the phased-array rigid coil. The system and method may be used for enhancing the signal-to-noise ratio, and/or reducing the scan acquisition time of acquired images in a parallel MRI scan of a patient who is breathing a hyperpolarized gas.

    摘要翻译： 提供了一种用可极化或超极化造影剂进行并行磁共振成像（“MRI”）的系统和方法。 造影剂可以以气体，液体或固体的形式提供。 该系统可以包括具有例如用于接收器的24通道相控阵列和用于发射器的2通道大环路的相控阵刚体线圈。 相控阵刚体线圈可以连接到低阻抗前置放大器，用于去耦相控阵刚体线圈中两个相邻线圈之间的强耦合。 该系统和方法可以用于增强信噪比，和/或减少在呼吸超极化气体的患者的并行MRI扫描中获取的图像的扫描获取时间。

    Crystal forming devices and systems and methods for using the same
    2.
    发明申请
    Crystal forming devices and systems and methods for using the same 有权
    晶体形成装置及其使用方法

    公开(公告)号：US20050201901A1

    公开(公告)日：2005-09-15

    申请号：US11043895

    申请日：2005-01-25

    申请人： Robert Grossman ,  Marc Unger ,  Phillip Lam ,  Hou-Pu Chou ,  Jake Kimball ,  Martin Pieprzyk

    发明人： Robert Grossman ,  Marc Unger ,  Phillip Lam ,  Hou-Pu Chou ,  Jake Kimball ,  Martin Pieprzyk

    IPC分类号： B01J19/00 ,  B01L3/00 ,  B01L3/06 ,  B01L9/00 ,  B01L99/00 ,  C30B7/00 ,  C30B29/58

    CPC分类号： C12Q1/68 ,  B01L3/0293 ,  B01L3/06 ,  B01L3/5025 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  B01L3/5635 ,  B01L3/565 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/0605 ,  B01L2300/0816 ,  B01L2300/14 ,  B01L2400/0487 ,  B01L2400/0655 ,  C30B7/00 ,  C30B29/58 ,  Y10T436/11

    摘要： The present invention provides for microfluidic devices and methods for their use. The invention further provides for apparatus and systems for using the microfluidic devices, analyze reactions carried out in the microfluidic devices, and systems to generate, store, organize, and analyze data generated from using the microfluidic devices. The invention further provides methods of using and making microfluidic systems and devices which, in some embodiments, are useful for crystal formation. In one embodiment, an apparatus includes a platen having a platen face with one or more fluid ports therein. The fluid ports spatially correspond to one or more wells on a surface of the microfluidic device. A platform for holding the microfluidic device relative to the platen is included, and a platen actuator for urging the platen against the microfluidic device so that at least one of the fluid ports of the platen is urged against one of the wells to form a pressure chamber comprising the well and the port, so that when pressurized fluid is introduced or removed into or from the pressure chamber through one of the ports, fluid pressure is changed therein.

    摘要翻译： 本发明提供了微流体装置及其使用方法。 本发明还提供了用于使用微流体装置的装置和系统，分析在微流体装置中进行的反应，以及用于生成，存储，组织和分析使用微流体装置产生的数据的系统。 本发明还提供了使用和制造微流体系统和装置的方法，在一些实施方案中，它们可用于晶体形成。 在一个实施例中，一种装置包括具有其中具有一个或多个流体端口的压板面的压板。 流体端口在空间上对应于微流体装置表面上的一个或多个孔。 包括用于相对于压板保持微流体装置的平台，以及用于将压板压靠在微流体装置上的压板致动器，使得压板的至少一个流体端口被推压到一个井中以形成压力室 包括井和端口，使得当压力流体通过其中一个端口被引入或从压力室移除时，流体压力在其中改变。

    Method and apparatus for improved magnetic resonance imaging data acquisition
    3.
    发明授权
    Method and apparatus for improved magnetic resonance imaging data acquisition 失效
    用于改善磁共振成像数据采集的方法和装置

    公开(公告)号：US06288543B1

    公开(公告)日：2001-09-11

    申请号：US08706185

    申请日：1996-08-30

    申请人： John Listerud ,  Robert Grossman

    发明人： John Listerud ,  Robert Grossman

    IPC分类号： G01V300

    CPC分类号： G01R33/4835 ,  G01R33/561

    摘要： A method for improved magnetic resonance imaging is disclosed herein. This method includes the step of interleaving a first slice-selective inversion recovery pulse within two slice-selective echo trains resulting from two other slice-selective inversion recovery pulses generated prior to the first pulse during a rapid spin echo sequence. In other words, the first slice-selective inversion recovery pulse is generated after receiving a first slice-selective echo train resulting from a second slice-selective inversion recovery pulse generated prior to the first pulse and before receiving a second slice-selective echo train resulting from a third slice-selective inversion recovery pulse generated prior to the generation of the first pulse.

    摘要翻译： 本文公开了一种用于改善磁共振成像的方法。 该方法包括以下步骤：在快速自旋回波序列期间，由在第一脉冲之前产生的另外两个切片选择性反转恢复脉冲产生的两个片选择性回波列内交织第一切片选择性反转恢复脉冲。 换句话说，在接收到在第一脉冲之前产生的第二切片选择性反转恢复脉冲产生的第一切片选择性回波串之前，在接收到第二切片选择回波串之前产生第一切片选择性反转恢复脉冲 从产生第一脉冲之前产生的第三切片选择性反转恢复脉冲。

    System for illustrating true three dimensional images in an enclosed medium
    4.
    发明申请
    System for illustrating true three dimensional images in an enclosed medium 审中-公开
    用于说明封闭介质中真实三维图像的系统

    公开(公告)号：US20100066730A1

    公开(公告)日：2010-03-18

    申请号：US11810485

    申请日：2007-06-05

    申请人： Robert Grossman

    发明人： Robert Grossman

    IPC分类号： G06T15/00

    CPC分类号： G02B27/2292 ,  H04N13/39

    摘要： A system for generating three-dimensional images within an enclosed volume wherein the images are oriented with X, Y, and a Z axes. The system includes a transparent housing capable of allowing a collimated light to pass therethrough, at least one laser for producing at least one beam of collimated light, a plurality of light activated units capable of emitting light at threshold θ when activated by the collimated light generated by the laser apparatus. In addition, the system also includes a suspension medium for suspending light-activated units. The suspension medium is a compound with a density capable of suspending the light activated units in a uniform fashion throughout the space

    摘要翻译： 一种用于在封闭体积内产生三维图像的系统，其中图像被定向为具有X，Y和Z轴。 该系统包括能够允许准直光通过的透明外壳，用于产生至少一个准直光束的至少一个激光器，能够在阈值处发射光的多个光激活单元; 当由激光装置产生的准直光激活时。 此外，该系统还包括用于悬挂光激活单元的悬架介质。 悬浮介质是具有密度的化合物，其能够在整个空间中以均匀的方式悬浮光活化单元

    Boater's keychain
    9.
    发明申请
    Boater's keychain 审中-公开
    船主钥匙扣

    公开(公告)号：US20050208848A1

    公开(公告)日：2005-09-22

    申请号：US10782154

    申请日：2004-02-18

    申请人： Robert Grossman

    发明人： Robert Grossman

    IPC分类号： B63B49/00 ,  B63C9/08

    CPC分类号： B63B49/00

    摘要： The boater's keychain includes a keychain, and a plurality of planar information cards connected to the keychain. Each of the planar information cards has two opposing sides imprinted with information, and each of the planar information cards is preferably formed of a buoyant sheet material.

    摘要翻译： 该船的钥匙扣包括钥匙扣和连接到该钥匙扣的多个平面信息卡。 每个平面信息卡具有两个相互打印信息的相对侧，每个平面信息卡优选地由浮力片材形成。