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公开(公告)号：US07753933B2
公开(公告)日：2010-07-13
申请号：US11101058
申请日：2005-04-06
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue includes a bioabsorbable, threaded plug carried by a delivery device. A guide wire is receivable through lumens in the plug and delivery device that includes wings on a bioabsorbable distal portion. With the wings collapsed, the guide wire is advanced through the passage into a blood vessel, the wings expanding once located within the vessel, and the guide wire is withdrawn until the wings contact the vessel wall. The plug is threaded into the passage over the guide wire until the plug is disposed adjacent the wings. The distal portion of the guide wire is secured to the plug, e.g., by compressing a collet within the plug lumen that seals the lumen, and is severed from a proximal portion thereof. Thus, the plug and distal portion are deployed with the plug sealing the passage.
摘要翻译： 用于密封通过组织的通道的装置包括由递送装置承载的生物可吸收的螺纹塞。 引导线可以通过包括生物可吸收的远端部分上的翼的塞子和输送装置中的内腔接收。 当翼部折叠时，导丝通过通道前进到血管中，翼部一旦位于血管内，则引导线被拉出，直到翼接触血管壁。 插头螺纹插入通过引导线的通道，直到插头靠近机翼。 引导线的远端部分固定到插塞上，例如通过压缩密封内腔的塞子腔内的夹头，并从其近端部分切断。 因此，塞子和远端部分展开，塞子密封通道。
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公开(公告)号：US06896692B2
公开(公告)日：2005-05-24
申请号：US10142735
申请日：2002-05-10
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue includes a plug including external threads, a lumen extending between its proximal and distal ends, and an annular collet slidably disposed within the lumen. The plug is carried on a distal end of a handle device that includes an inner member with a distal end that is slidable axially within the lumen of the body for moving the collet into a reduced cross-sectional region of the lumen, thereby compressing the collet to seal the lumen, and for deploying the plug from the handle device. During use, the plug is threaded into a passage through tissue over a guide wire. Once a desired location is reached, the plug is deployed from the handle device, thereby compressing the collet and sealing the lumen. The guide wire and handle device are removed, leaving the plug to seal the passage.
摘要翻译： 用于密封通过组织的通道的装置包括包括外螺纹的塞子，在其近端和远端之间延伸的内腔和可滑动地设置在内腔内的环形夹头。 插头被承载在手柄装置的远端上，该手柄装置包括内部构件，该内部构件具有在主体的内腔内可轴向滑动的远端，用于将夹头移动到管腔的减小的横截面区域中，从而压缩夹头 以密封管腔，并且用于从手柄装置部署塞子。 在使用过程中，插头穿过导丝上的组织通过。 一旦到达期望的位置，插头从手柄装置展开，从而压缩夹头并密封管腔。 引导线和手柄装置被移除，留下塞子以密封通道。
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公开(公告)号：US06890343B2
公开(公告)日：2005-05-10
申请号：US10143514
申请日：2002-05-10
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue includes a bioabsorbable, threaded plug carried by a delivery device. A guide wire is receivable through lumens in the plug and delivery device that includes wings on a bioabsorbable distal portion. With the wings collapsed, the guide wire is advanced through the passage into a blood vessel, the wings expanding once located within the vessel, and the guide wire is withdrawn until the wings contact the vessel wall. The plug is threaded into the passage over the guide wire until the plug is disposed adjacent the wings. The distal portion of the guide wire is secured to the plug, e.g., by compressing a collet within the plug lumen that seals the lumen, and is severed from a proximal portion thereof. Thus, the plug and distal portion are deployed with the plug sealing the passage.
摘要翻译： 用于密封通过组织的通道的装置包括由递送装置承载的生物可吸收的螺纹塞。 引导线可以通过包括生物可吸收的远端部分上的翼的塞子和输送装置中的内腔接收。 当翼部折叠时，导丝通过通道前进到血管中，翼部一旦位于血管内，则引导线被拉出，直到翼接触血管壁。 插头螺纹插入通过引导线的通道，直到插头靠近机翼。 引导线的远端部分固定到插塞上，例如通过压缩密封内腔的塞子腔内的夹头，并从其近端部分切断。 因此，塞子和远端部分展开，塞子密封通道。
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公开(公告)号：US08888812B2
公开(公告)日：2014-11-18
申请号：US13295734
申请日：2011-11-14
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue includes a plug including external threads, a lumen extending between its proximal and distal ends, and an annular collet slidably disposed within the lumen. The plug is carried on a distal end of a handle device that includes an inner member with a distal end that is slidable axially within the lumen of the body for moving the collet into a reduced cross-sectional region of the lumen, thereby compressing the collet to seal the lumen, and for deploying the plug from the handle device. During use, the plug is delivered into a passage through tissue over a guide wire. Once a desired location is reached, the plug is deployed from the handle device, thereby compressing the collet and sealing the lumen. The guide wire and handle device are removed, leaving the plug to seal the passage.
摘要翻译： 用于密封通过组织的通道的装置包括包括外螺纹的塞子，在其近端和远端之间延伸的内腔和可滑动地设置在内腔内的环形夹头。 插头被承载在手柄装置的远端上，该手柄装置包括内部构件，该内部构件具有在主体的内腔内可轴向滑动的远端，用于将夹头移动到管腔的减小的横截面区域中，从而压缩筒夹 以密封管腔，并且用于从手柄装置部署塞子。 在使用过程中，塞子通过导丝被输送到穿过组织的通道中。 一旦到达期望的位置，插头从手柄装置展开，从而压缩夹头并密封管腔。 引导线和手柄装置被移除，留下塞子以密封通道。
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公开(公告)号：US20100274281A1
公开(公告)日：2010-10-28
申请号：US12833643
申请日：2010-07-09
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue includes a bioabsorbable, threaded plug carried by a delivery device. A guide wire is receivable through lumens in the plug and delivery device that includes wings on a bioabsorbable distal portion. With the wings collapsed, the guide wire is advanced through the passage into a blood vessel, the wings expanding once located within the vessel, and the guide wire is withdrawn until the wings contact the vessel wall. The plug is threaded into the passage over the guide wire until the plug is disposed adjacent the wings. The distal portion of the guide wire is secured to the plug, e.g., by compressing a collet within the plug lumen that seals the lumen, and is severed from a proximal portion thereof. Thus, the plug and distal portion are deployed with the plug sealing the passage.
摘要翻译： 用于密封通过组织的通道的装置包括由递送装置承载的生物可吸收的螺纹塞。 引导线可以通过包括生物可吸收的远端部分上的翼的塞子和输送装置中的内腔接收。 当翼部折叠时，导丝通过通道前进到血管中，翼部一旦位于血管内，则引导线被拉出，直到翼接触血管壁。 插头螺纹插入通过引导线的通道，直到插头靠近机翼。 引导线的远端部分固定到插塞上，例如通过压缩密封内腔的塞子腔内的夹头，并从其近端部分切断。 因此，塞子和远端部分展开，塞子密封通道。
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6.发明申请公开(公告)号：US20120065671A1
公开(公告)日：2012-03-15
申请号：US13295734
申请日：2011-11-14
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue includes a plug including external threads, a lumen extending between its proximal and distal ends, and an annular collet slidably disposed within the lumen. The plug is carried on a distal end of a handle device that includes an inner member with a distal end that is slidable axially within the lumen of the body for moving the collet into a reduced cross-sectional region of the lumen, thereby compressing the collet to seal the lumen, and for deploying the plug from the handle device. During use, the plug is delivered into a passage through tissue over a guide wire. Once a desired location is reached, the plug is deployed from the handle device, thereby compressing the collet and sealing the lumen. The guide wire and handle device are removed, leaving the plug to seal the passage.
摘要翻译： 用于密封通过组织的通道的装置包括包括外螺纹的塞子，在其近端和远端之间延伸的内腔和可滑动地设置在内腔内的环形夹头。 插头被承载在手柄装置的远端上，该手柄装置包括内部构件，该内部构件具有在主体的内腔内可轴向滑动的远端，用于将夹头移动到管腔的减小的横截面区域中，从而压缩夹头 以密封管腔，并且用于从手柄装置部署塞子。 在使用过程中，塞子通过导丝被输送到穿过组织的通道中。 一旦到达期望的位置，插头从手柄装置展开，从而压缩夹头并密封管腔。 引导线和手柄装置被移除，留下塞子以密封通道。
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公开(公告)号：US08057510B2
公开(公告)日：2011-11-15
申请号：US11121715
申请日：2005-05-03
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue includes a plug including external threads, a lumen extending between its proximal and distal ends, and an annular collet slidably disposed within the lumen. The plug is carried on a distal end of a handle device that includes an inner member with a distal end that is slidable axially within the lumen of the body for moving the collet into a reduced cross-sectional region of the lumen, thereby compressing the collet to seal the lumen, and for deploying the plug from the handle device. During use, the plug is delivered into a passage through tissue over a guide wire. Once a desired location is reached, the plug is deployed from the handle device, thereby compressing the collet and sealing the lumen. The guide wire and handle device are removed, leaving the plug to seal the passage.
摘要翻译： 用于密封通过组织的通道的装置包括包括外螺纹的塞子，在其近端和远端之间延伸的内腔和可滑动地设置在内腔内的环形夹头。 插头被承载在手柄装置的远端上，该手柄装置包括内部构件，该内部构件具有在主体的内腔内可轴向滑动的远端，用于将夹头移动到管腔的减小的横截面区域中，从而压缩筒夹 以密封管腔，并且用于从手柄装置部署塞子。 在使用过程中，塞子通过导丝被输送到穿过组织的通道中。 一旦到达期望的位置，插头从手柄装置展开，从而压缩夹头并密封管腔。 引导线和手柄装置被移除，留下塞子以密封通道。
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公开(公告)号：US08926603B2
公开(公告)日：2015-01-06
申请号：US13044318
申请日：2011-03-09
CPC分类号： A61B18/1492 , A61B17/00234 , A61B17/3478 , A61B18/1477 , A61B34/20 , A61B34/25 , A61B34/30 , A61B34/37 , A61B34/71 , A61B34/76 , A61B2017/00199 , A61B2017/00243 , A61B2018/1425 , A61B2034/102 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/301 , A61B2034/715 , A61B2034/742 , A61B2090/065 , A61B2090/378
摘要： A method for modifying a geometry of a collagenous tissue mass includes heating the collagenous tissue mass to a temperature sufficient to cause denaturation, and introducing a biocompatible fixative, such as genepin, into the collagenous tissue mass.
摘要翻译： 修饰胶原组织块的几何形状的方法包括将胶原组织块加热至足以引起变性的温度，并将生物相容性固定剂（如genepin）导入胶原组织块。
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公开(公告)号：US08617102B2
公开(公告)日：2013-12-31
申请号：US13358468
申请日：2012-01-25
申请人： Frederic H. Moll , Daniel T. Wallace , Gregory J. Stahler , David F. Moore , Daniel T. Adams , Kenneth M. Martin , Robert G. Younge , Michael R. Zinn , Gunter D. Niemeyer , David C. Lundmark
发明人： Frederic H. Moll , Daniel T. Wallace , Gregory J. Stahler , David F. Moore , Daniel T. Adams , Kenneth M. Martin , Robert G. Younge , Michael R. Zinn , Gunter D. Niemeyer , David C. Lundmark
IPC分类号： A61M31/00
CPC分类号： A61B34/30 , A61B1/018 , A61B1/2676 , A61B1/273 , A61B5/0006 , A61B5/053 , A61B5/7285 , A61B6/541 , A61B8/0808 , A61B8/12 , A61B17/0482 , A61B17/062 , A61B18/08 , A61B34/20 , A61B34/25 , A61B34/37 , A61B34/71 , A61B34/74 , A61B34/76 , A61B46/10 , A61B90/361 , A61B90/39 , A61B90/50 , A61B2017/00238 , A61B2017/00243 , A61B2017/00296 , A61B2017/003 , A61B2017/00336 , A61B2017/00743 , A61B2017/00805 , A61B2034/102 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/2063 , A61B2034/256 , A61B2034/301 , A61B2034/303 , A61B2034/715 , A61B2090/035 , A61B2090/062 , A61B2090/065 , A61B2090/364 , A61B2090/376 , A61B2090/378 , A61B2090/3784 , A61M25/0105 , A61M25/0113 , A61M25/0147 , A61M2025/0004 , B33Y70/00 , B33Y80/00
摘要： The apparatus of one embodiment of the present invention is comprised of a flexible sheath instrument, a flexible guide instrument, and a tool. The flexible sheath instrument comprises a first instrument base removably coupleable to an instrument driver and defines a sheath instrument working lumen. The flexible guide instrument comprises a second instrument base removably coupleable to the instrument driver and is threaded through the sheath instrument working lumen. The guide instrument also defines a guide instrument working lumen. The tool is threaded through the guide instrument working lumen. For this embodiment of the apparatus, the sheath instrument and guide instrument are independently controllable relative to each other.
摘要翻译： 本发明的一个实施例的装置包括柔性护套仪器，柔性引导器械和工具。 柔性护套仪器包括可移除地耦合到仪器驱动器并且限定护套仪器工作腔的第一仪器基座。 柔性引导仪器包括可移除地联接到仪器驱动器并且穿过护套仪器工作腔的第二仪器基座。 引导仪器还定义了工具内腔的导向仪器。 该工具穿过导向仪工作腔。 对于该装置的该实施例，护套仪器和引导器具可以彼此独立地控制。
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公开(公告)号：US20130035537A1
公开(公告)日：2013-02-07
申请号：US13310596
申请日：2011-12-02
申请人： Daniel T. Wallace , Dale Bergman , Ruchi Choksi , Aaron Grogan
发明人： Daniel T. Wallace , Dale Bergman , Ruchi Choksi , Aaron Grogan
IPC分类号： A61M25/092 , A61M36/12
CPC分类号： A61B34/30 , A61B18/1477 , A61B18/1492 , A61B2017/00477 , A61B2018/00029 , A61B2018/00529 , A61B2034/301 , A61N5/1007 , A61N7/02
摘要： A method of manipulating an elongate member in at least two degrees of freedom includes holding an elongate member between two rotary members that define respective rotational axes, the elongate member having a flexible proximal portion, a distal rigid needle attached to the proximal portion, and an operative element for delivering energy, the needle having a distal port, actuating at least one of the rotary members in a rotational direction about its rotational axis to generate a corresponding linear motion of the elongate member along a longitudinal axis of the elongate member, and actuating at least one of the rotary members in a linear direction along its rotational axis to generate a corresponding rotational motion of the elongate member about the longitudinal axis of the elongate member.
摘要翻译： 一种以至少两个自由度操纵细长构件的方法包括：将细长构件保持在限定相应旋转轴线的两个旋转构件之间，细长构件具有柔性近侧部分，附接到近侧部分的远侧刚性针，以及 用于传递能量的所述操作元件，所述针具有远端口，围绕其旋转轴线沿旋转方向致动所述旋转构件中的至少一个，以沿所述细长构件的纵向轴线产生所述细长构件的相应的线性运动，并致动 旋转构件中的至少一个沿着其旋转轴线沿直线方向，以产生细长构件围绕细长构件的纵向轴线的相应旋转运动。
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