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公开(公告)号:US06283983B1
公开(公告)日:2001-09-04
申请号:US09192554
申请日:1998-08-10
IPC分类号: A61M2900
CPC分类号: A61B17/11 , A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0057 , A61B17/0643 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B17/1219 , A61B17/320725 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/1205 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00869 , A61B2018/1425 , A61B2090/378 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0004 , A61M2025/0076 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M2025/1052 , A61M2210/125
摘要: Methods and devices for percutaneous, in situ coronary bypass wherein a tissue puncturing catheter is used to form blood flow paths between an artery and an adjacent vein such that arterial blood will flow through a segment of the adjacent vein, thereby bypassing a lesion in the artery. The tissue puncturing catheter comprises a flexible catheter having a tissue puncturing apparatus such as a sharp tipped member, an electro-surgical apparatus or a laser beam passable therefrom to create the desired blood flow paths between the artery and vein. Stents are provided for facilitating blood flow through the blood flow paths and the segment of the vein used as the bypass conduit. One such stent is specially constructed to carry arterial blood in one direction through the vein segment while allowing venous blood to continue to flow in the opposite direction through that venous segment.
摘要翻译: 用于经皮的原位冠状动脉旁路的方法和装置,其中组织穿刺导管用于形成动脉和相邻静脉之间的血流路径,使得动脉血液将流过相邻静脉的一段,从而绕过动脉中的病变 。 组织穿刺导管包括柔性导管,其具有组织穿刺装置,例如尖锐的尖端构件,电外科手术装置或可从其穿过的激光束,以在动脉和静脉之间产生所需的血流路径。 提供了用于促进血液流过血流路径和用作旁路导管的静脉段的支架。 一种这样的支架被特别构造成通过静脉段沿一个方向携带动脉血,同时允许静脉血继续沿相反方向流过该静脉段。
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公开(公告)号:US06969373B2
公开(公告)日:2005-11-29
申请号:US09967681
申请日:2001-09-28
IPC分类号: A61B17/00 , A61B17/34 , A61M5/145 , A61M5/158 , A61M5/168 , A61M5/31 , A61M5/32 , A61M25/00 , A61M5/178 , A61M1/00
CPC分类号: A61M5/158 , A61B17/3478 , A61B2017/00247 , A61B2018/00392 , A61M5/14546 , A61M5/16813 , A61M5/3291 , A61M2005/14513 , A61M2005/3123 , A61M2025/0008 , A61M2025/0057 , A61M2025/0079 , A61M2025/0081 , A61M2025/0091
摘要: A medical device is provided having a needle or a catheter, insertable into a living body, which defines a plurality of holes in fluid communication with a central lumen. The holes may be of various patterns located and angled to create a desired injectate cloud pattern when an injectate is forced through the central lumen and through the plurality of holes. One embodiment provides various designs including a moveable sheath or stylet used to selectively occlude one or more of the holes while in use, thereby providing an operating physician a way to manipulate the cloud pattern anytime during the introduction of the injectate. A reducer may be used in conjunction with these needles which provides an increased degree of control when injecting very small quantities of fluid.
摘要翻译: 提供具有可插入生物体中的针或导管的医疗装置,其限定与中心腔流体连通的多个孔。 当注射剂被迫穿过中心腔并穿过多个孔时,孔可以是各种图案,其定位和成角度以产生期望的注射云图案。 一个实施例提供了各种设计,包括用于在使用中选择性地闭塞一个或多个孔的可移动护套或探针,从而为操作医师提供在注射器引入期间随时操作云图案的方式。 减速器可以与这些针结合使用,当注射非常少量的流体时,可以提供更高程度的控制。
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公开(公告)号:US5728132A
公开(公告)日:1998-03-17
申请号:US629022
申请日:1996-04-08
CPC分类号: A61B17/3417 , A61B17/0057 , A61B17/00491 , A61B17/3498
摘要: An instrument for achieving rapid hemostasis at the conclusion of a catheterization procedure comprises a device for injecting a fluid hemostatic agent into a puncture wound that is operatively associated with a conventional introducer sheath component of the introducer used to gain access to a blood vessel using the Seldinger technique. The hemostatic agent injection device includes a tubular member that can be concentrically disposed with a tubular introducer sheath so as to be slidable therealong and where the injection device includes a hemostatic agent inlet port at a proximal end thereof and an ejection port at a distal end, the two ports being interconnected by a lumen. In a first embodiment, the hemostatic agent injection device is adapted to coaxially surround the introducer sheath and in an alternate embodiment, the injection device is coaxially disposed within the lumen of the introducer sheath.
摘要翻译: 用于在导管插入术结束时实现快速止血的仪器包括用于将流体止血剂注射到穿刺伤口中的装置,所述穿刺伤口与用于使用所述Seldinger进入血管的导引器的常规导引器鞘部件可操作地相关联 技术。 止血剂注射装置包括管状构件,该管状构件可以同心地设置有管状导引鞘,以便能够沿着其滑动,并且其中注射装置包括其近端处的止血剂入口和远端的排出口, 两个端口由管腔相互连接。 在第一实施例中,止血剂注射装置适于同轴地包围导引鞘,并且在替代实施例中,注射装置同轴地设置在导引鞘的内腔中。
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公开(公告)号:US5573520A
公开(公告)日:1996-11-12
申请号:US329691
申请日:1994-10-26
申请人: Robert S. Schwartz , David R. Holmes , Frederick S. Halverson , James V. Donadio, III , David Berry
发明人: Robert S. Schwartz , David R. Holmes , Frederick S. Halverson , James V. Donadio, III , David Berry
CPC分类号: A61M25/0013 , A61M25/0043 , B29C41/20 , B29C47/0023 , B29C47/023 , C23F1/02 , A61M2025/09066 , A61M2025/091 , A61M25/0051 , A61M25/0053 , A61M25/0054 , A61M25/0662 , A61M25/09 , B29C47/0026 , B29L2023/001 , B29L2031/7542
摘要: An apparatus for use as a catheter, a guidewire, a catheter sheath for use with catheter introducers or a drug infusion catheter/guidewire. The apparatus includes a flexible tubular member with an encasing covering the tubular member that creates a fluid-tight seal around the periphery of the tubular member. The tubular member is self-supporting and includes a plurality of apertures therein in a predetermined configuration to increase the flexibility of the tubular member.
摘要翻译: 用作导管的装置,导丝,用于导管导引器或药物输注导管/导丝的导管护套。 该装置包括柔性管状构件,其具有覆盖管状构件的封装,其围绕管状构件的周边产生流体密封的密封。 管状构件是自支撑的并且在预定构造中包括多个孔,以增加管状构件的柔性。
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公开(公告)号:US06645143B2
公开(公告)日:2003-11-11
申请号:US09961564
申请日:2001-09-20
IPC分类号: A61B500
CPC分类号: A61F2/82 , A61B5/0031 , A61B5/02055 , A61B5/0215 , A61B5/026 , A61B5/413 , A61B5/6882 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623
摘要: A medical monitoring apparatus designed to be implanted in the vascular system is capable of sensing and transmitting via a telemetry link to an external monitor both pressure and temperature information. An internally or externally powered microcircuit component is supported on a stent-like structure and adapted to be placed in the vascular system. Placement in the ventricular septum permits measurement of pressure and temperature in the left ventricle without introducing thrombus generating materials in the left ventricle.
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公开(公告)号:US08323913B2
公开(公告)日:2012-12-04
申请号:US13103889
申请日:2011-05-09
CPC分类号: G01N33/5091 , C07K14/4715 , G01N33/564 , G01N33/689 , G01N33/6893 , G01N2800/324 , G01N2800/368
摘要: Use of pregnancy-associated plasma protein-A as a marker for inflammatory conditions, and in particular, for acute coronary syndromes is described.
摘要翻译: 描述了使用怀孕相关血浆蛋白-A作为炎性病症的标志物,特别是用于急性冠状动脉综合征。
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公开(公告)号:US6126649A
公开(公告)日:2000-10-03
申请号:US329386
申请日:1999-06-10
CPC分类号: A61M25/0138 , A61M25/0147 , A61B2017/22041 , A61B2017/22045 , A61M2025/0177
摘要: A steerable catheter in which a guidewire can serve a dual purpose of deflecting a bendable element at a distal end of the steerable catheter and as a guidewire to facilitate the placement of a working catheter within the vascular system. The guidewire is adapted to be slidingly received within routing eyelets or the like where one of such eyelets is disposed at a distal end of the bendable element and another near the proximal end thereof. The guidewire can be readily advanced in the distal direction relative to the steerable catheter, but tensioning of the guidewire at its proximal end serves to deflect and bend the bendable element.
摘要翻译: 可导向的导管,其中导丝可以用于在可操纵导管的远端处偏转可弯曲元件的双重目的,并且用作导丝,以便于在血管系统内放置工作导管。 导丝适于滑动地容纳在布置孔眼等内,其中这些孔眼之一设置在可弯曲元件的远端,另一个靠近其近端。 导丝可以相对于可导向导管在远端方向上容易地前进,但是导丝在其近端处的张紧用于使可弯曲元件偏转和弯曲。
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公开(公告)号:US20100285510A1
公开(公告)日:2010-11-11
申请号:US12785893
申请日:2010-05-24
IPC分类号: G01N33/53
CPC分类号: G01N33/5091 , C07K14/4715 , G01N33/564 , G01N33/689 , G01N33/6893 , G01N2800/324 , G01N2800/368
摘要: Use of pregnancy-associated plasma protein-A as a marker for inflammatory conditions, and in particular, for acute coronary syndromes is described.
摘要翻译: 描述了使用怀孕相关血浆蛋白-A作为炎性病症的标志物,特别是用于急性冠状动脉综合征。
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公开(公告)号:US06605061B2
公开(公告)日:2003-08-12
申请号:US09880575
申请日:2001-06-13
IPC分类号: A61M5178
CPC分类号: A61M25/0068 , A61B2017/00247 , A61B2018/00392 , A61M25/008 , A61M25/0084 , A61M2025/009
摘要: A catheter for injecting medicants into the endocardium, myocardium or other portions of the cardiovascular system is presented where the catheter has apertures therein for ejection and retraction of a needle. The catheter is designed for the apertures in the catheter to press against the tissue to be injected in the heart while the heart is beating. A needle for inserting a prescribed dose of a medicant is ejected through the aperture and a plunger, pump, or diaphragm is moved to deliver a dose of the medicant to tissue adjacent the aperture. By use of the catheter gene therapy, wherein a small does of a gene are injected into the endocardium of the right or left ventricle, can be used to grow new blood vessels in the injected area of a damaged heart. The apertures in the catheter can be spaced at a prescribed distance for the dosage of medicant to form a precise pattern of injections in the area to be treated. The catheters may be used for any treatments of a human or animal patient where injections are required in the heart, veins or arteries of the cardiovascular system.
摘要翻译: 提供用于将药剂注射到心内膜,心肌或心血管系统的其它部分的导管,其中导管在其中具有孔,用于针的弹出和缩回。 该导管被设计用于在心脏跳动时将导管中的孔压在组织上以被注射到心脏中。 用于插入规定剂量的药剂的针通过孔排出,移动柱塞,泵或隔膜以将剂量的药剂递送到邻近孔的组织。 通过使用其中将小的基因注入右心室或左心室的导管基因治疗可用于在损伤的心脏的注射区域中生长新的血管。 导管中的孔可以间隔规定的距离,用于药物的剂量以在待治疗的区域中形成精确的注射模式。 导管可用于需要在心血管系统的心脏,静脉或动脉中注射的人或动物患者的任何治疗。
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公开(公告)号:US06371942B1
公开(公告)日:2002-04-16
申请号:US09159008
申请日:1998-09-23
IPC分类号: A61M500
CPC分类号: A61M39/24 , A61M2039/2473 , A61M2039/2486 , A61M2039/2493 , Y10T137/87571 , Y10T137/87652 , Y10T137/87684 , Y10T137/88054
摘要: An automatic manifold for a catheter assembly. Valve means automatically open and close flow between a liquid supply port for connection to injection means and a liquid delivery port for communication with the catheter assembly. A pressure sensor is integrated into the manifold. The manifold also includes a quick-disconnect coupling mechanism for a liquid supply port.
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