Process for the synthesis of pyrazolopyrimidines
    1.
    发明申请
    Process for the synthesis of pyrazolopyrimidines 审中-公开
    合成吡唑并嘧啶的方法

    公开(公告)号:US20070060744A1

    公开(公告)日:2007-03-15

    申请号:US11448218

    申请日:2006-06-06

    IPC分类号: C07H19/04

    CPC分类号: C07H19/04 C07H19/044

    摘要: The present invention provides a nucleoside comprising a pyrazolopyrimidine base and a process for producing the same. In particular, the processes of the present invention comprises using a halogenated pyrazolopyrimidine base and removing the halogen after the base is coupled to a sugar moiety. The presence of the halogen on the nucleoside base allows facile and economical production of a large quantity of nucleosides.

    摘要翻译: 本发明提供了包含吡唑并嘧啶碱的核苷及其制备方法。 特别地,本发明的方法包括使用卤代吡唑并嘧啶碱,并且在碱偶联到糖部分后除去卤素。 在核苷碱基上存在卤素可以容易地和经济地生产大量的核苷。