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公开(公告)号：US5645734A
公开(公告)日：1997-07-08
申请号：US559090
申请日：1995-02-23
申请人： Rodney S. Kenley , Dawn Matthews , Dennis M. Treu , Frederick H. Peter, Jr. , Thomas M. Feldsein , H. Gordon Minns
发明人： Rodney S. Kenley , Dawn Matthews , Dennis M. Treu , Frederick H. Peter, Jr. , Thomas M. Feldsein , H. Gordon Minns
IPC分类号： A61M1/14 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/34 , A61M1/36 , A61M39/16 , B01D17/00 , B01D17/09 , B01D61/02 , B01D61/04 , B01D61/12 , B01D61/24 , B01D61/32 , B01D65/02 , B01D65/10 , C02F1/28 , C02F1/44 , C02F1/68 , F16K17/04 , B01D61/30
CPC分类号： B01D65/102 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1649 , A61M1/165 , A61M1/1656 , A61M1/166 , A61M1/1662 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1682 , A61M1/1684 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M1/1692 , A61M1/1694 , A61M1/288 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3465 , A61M1/3468 , A61M1/3626 , A61M1/3627 , A61M1/3629 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , B01D61/02 , B01D61/025 , B01D61/04 , B01D61/12 , B01D61/32 , B01D65/022 , B01D65/104 , C02F1/441 , F16K17/0453 , A61M1/1658 , A61M2205/12 , A61M2205/15 , A61M2205/17 , A61M2205/3382 , A61M2205/3386 , A61M2205/505 , A61M2205/6072 , A61M2205/705 , A61M2205/707 , A61M2205/7554 , A61M2205/7581 , A61M2206/11 , A61M39/16 , B01D2311/04 , B01D2321/04 , B01D2321/16 , B01D2321/32 , Y10S210/929 , Y10S215/03 , Y10T137/7722 , Y10T137/7794 , Y10T137/7796 , Y10T137/7799
摘要： A method for maintaining separation of old and new dialysate in a dialysate preparation tank is disclosed. The new dialysate is stored in the tank at a first temperature and withdrawn from the bottom of the tank. The dialysate is circulated through a dialyzer, and then returned to the tank at the top of the tank at a higher temperature in a substantially non-turbulent manner. The temperature differential between old and new dialysate and the manner of withdrawing and reintroducing the dialysate to the tank cooperate to form discrete zones of old and new dialysate without substantial mixing of the dialysate in the two zones.
摘要翻译： 公开了一种用于维持透析液制备罐中新旧透析液分离的方法。 新的透析液以第一温度储存在储罐中，并从罐的底部取出。 透析液通过透析器循环，然后在较高温度下以基本上非湍流的方式返回到罐顶部的罐中。 旧的和新的透析液之间的温差以及将透析液抽出和重新引入到罐中的方式配合形成新旧透析液的离散区，而不会在两个区域中透析液的大量混合。
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公开(公告)号：US5674404A
公开(公告)日：1997-10-07
申请号：US558213
申请日：1996-04-30
申请人： Rodney S. Kenley , Dawn Matthews , Douglas L. Wilkerson , Dennis M. Treu , Frederick H. Peter, Jr. , Tom L. Brose , Thomas M. Feldsein
发明人： Rodney S. Kenley , Dawn Matthews , Douglas L. Wilkerson , Dennis M. Treu , Frederick H. Peter, Jr. , Tom L. Brose , Thomas M. Feldsein
IPC分类号： A61M1/14 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/34 , A61M1/36 , A61M39/16 , B01D17/00 , B01D17/09 , B01D61/02 , B01D61/04 , B01D61/12 , B01D61/24 , B01D61/32 , B01D65/02 , B01D65/10 , C02F1/28 , C02F1/44 , C02F1/68 , F16K17/04
CPC分类号： B01D65/102 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1649 , A61M1/165 , A61M1/1656 , A61M1/166 , A61M1/1662 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1682 , A61M1/1684 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M1/1692 , A61M1/1694 , A61M1/288 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3465 , A61M1/3468 , A61M1/3626 , A61M1/3627 , A61M1/3629 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , B01D61/02 , B01D61/025 , B01D61/04 , B01D61/12 , B01D61/32 , B01D65/022 , B01D65/104 , C02F1/441 , F16K17/0453 , A61M1/1658 , A61M2205/12 , A61M2205/15 , A61M2205/17 , A61M2205/3382 , A61M2205/3386 , A61M2205/505 , A61M2205/6072 , A61M2205/705 , A61M2205/707 , A61M2205/7554 , A61M2205/7581 , A61M2206/11 , A61M39/16 , B01D2311/04 , B01D2321/04 , B01D2321/16 , B01D2321/32 , Y10S210/929 , Y10S215/03 , Y10T137/7722 , Y10T137/7794 , Y10T137/7796 , Y10T137/7799
摘要： A method is described for automatically testing the integrity of a dialyzer filter within a dialysis machine. The method consists of substantially removing fluids which may be present from the blood side of the dialyzer filter, pumping air into the blood side of the dialyzer filter with a blood pump to pressurize the dialyzer filter, and measuring the pressurization of the dialyzer filter. If the dialyzer filter pressurizes, the rate of decay of pressurization is measured. The pressurization and rate of decay are indicative of the integrity of the membrane of the dialyzer filter.
摘要翻译： 描述了一种自动测试透析机内透析器过滤器完整性的方法。 该方法包括基本上除去可能存在于透析器过滤器的血液侧的流体，用血泵将空气泵入透析器过滤器的血液侧，对透析器过滤器加压，并测量透析器过滤器的加压。 如果透析器过滤器加压，则测量加压衰减速率。 加压和衰减速率表示透析器过滤器的膜的完整性。
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公开(公告)号：US5690831A
公开(公告)日：1997-11-25
申请号：US559124
申请日：1995-11-17
申请人： Rodney S. Kenley , Dawn Matthews , Dennis M. Treu , Frederick H. Peter, Jr. , Thomas M. Feldsein
发明人： Rodney S. Kenley , Dawn Matthews , Dennis M. Treu , Frederick H. Peter, Jr. , Thomas M. Feldsein
IPC分类号： A61M1/14 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/34 , A61M1/36 , A61M39/16 , B01D17/00 , B01D17/09 , B01D61/02 , B01D61/04 , B01D61/12 , B01D61/24 , B01D61/32 , B01D65/02 , B01D65/10 , C02F1/28 , C02F1/44 , C02F1/68 , F16K17/04
CPC分类号： B01D65/102 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1649 , A61M1/165 , A61M1/1656 , A61M1/166 , A61M1/1662 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1682 , A61M1/1684 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M1/1692 , A61M1/1694 , A61M1/288 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3465 , A61M1/3468 , A61M1/3626 , A61M1/3627 , A61M1/3629 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , B01D61/02 , B01D61/025 , B01D61/04 , B01D61/12 , B01D61/32 , B01D65/022 , B01D65/104 , C02F1/441 , F16K17/0453 , A61M1/1658 , A61M2205/12 , A61M2205/15 , A61M2205/17 , A61M2205/3382 , A61M2205/3386 , A61M2205/505 , A61M2205/6072 , A61M2205/705 , A61M2205/707 , A61M2205/7554 , A61M2205/7581 , A61M2206/11 , A61M39/16 , B01D2311/04 , B01D2321/04 , B01D2321/16 , B01D2321/32 , Y10S210/929 , Y10S215/03 , Y10T137/7722 , Y10T137/7794 , Y10T137/7796 , Y10T137/7799
摘要： A method is described herein for automatically rinsing blood back to a patient. The method comprises the steps of pumping dialysate (or, alternatively, saline solution) through a dialyzer into an extracorporeal circuit, and pumping blood in the extracorporeal circuit out the arterial and venous lines back to the patient. Optical sensors monitor the concentration of blood in the arterial and venous lines as the blood is being pumped from the extracorporeal circuit back to the patient. The return flow of blood is ceased when the concentration of blood in the arterial and venous lines drops to a predetermined threshold level, thereby preventing excess fluids from being returned to the patient.
摘要翻译： 本文描述了一种用于将血液自动冲洗回患者的方法。 该方法包括以下步骤：将透析液（或替代地，盐水溶液）通过透析器泵送到体外循环中，并将体外循环中的血液从动脉和静脉回路输送回患者。 当血液从体外循环泵送回病人时，光学传感器监测动脉和静脉血液中的血液浓度。 当动脉和静脉血液中的血液浓度下降到预定的阈值水平时，停止返回血液，从而防止多余的流体被返回到患者体内。
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公开(公告)号：US5714060A
公开(公告)日：1998-02-03
申请号：US707509
申请日：1996-09-04
申请人： Rodney S. Kenley , Dennis M. Treu , Frederick H. Peter, Jr. , Thomas M. Feldsein , Kenneth E. Pawlak , Wayne F. Adolf
发明人： Rodney S. Kenley , Dennis M. Treu , Frederick H. Peter, Jr. , Thomas M. Feldsein , Kenneth E. Pawlak , Wayne F. Adolf
IPC分类号： A61M1/14 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/34 , A61M1/36 , A61M39/16 , B01D17/00 , B01D17/09 , B01D61/02 , B01D61/04 , B01D61/12 , B01D61/24 , B01D61/32 , B01D65/02 , B01D65/10 , C02F1/28 , C02F1/44 , C02F1/68 , F16K17/04 , B01D35/00
CPC分类号： B01D65/102 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1649 , A61M1/165 , A61M1/1656 , A61M1/166 , A61M1/1662 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1682 , A61M1/1684 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M1/1692 , A61M1/1694 , A61M1/288 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3465 , A61M1/3468 , A61M1/3626 , A61M1/3627 , A61M1/3629 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , B01D61/02 , B01D61/025 , B01D61/04 , B01D61/12 , B01D61/32 , B01D65/022 , B01D65/104 , C02F1/441 , F16K17/0453 , A61M1/1658 , A61M2205/12 , A61M2205/15 , A61M2205/17 , A61M2205/3382 , A61M2205/3386 , A61M2205/505 , A61M2205/6072 , A61M2205/705 , A61M2205/707 , A61M2205/7554 , A61M2205/7581 , A61M2206/11 , A61M39/16 , B01D2311/04 , B01D2321/04 , B01D2321/16 , B01D2321/32 , Y10S210/929 , Y10S215/03 , Y10T137/7722 , Y10T137/7794 , Y10T137/7796 , Y10T137/7799
摘要： A hemodialysis machine has ports of a disinfection manifold for receiving the arterial and venous line connectors terminating the arterial and venous lines. The ports are in fluid communication with a hydraulic system that circulates disinfection fluid through the machine including the extracorporeal circuit. The ports are constructed so as to provide a gap extending circumferentially around the arterial and venous line connectors. When the disinfection fluid circulates through the ports of the disinfection manifold, the fluid circulates around the external surfaces of the connectors as well as through the internal fluid passages, thereby insuring a complete disinfection of the connectors.
摘要翻译： 血液透析机具有消毒歧管的端口，用于接收端接动脉和静脉线的动脉和静脉管路连接器。 端口与液压系统流体连通，该液压系统使消毒液体循环通过包括体外回路的机器。 端口被构造成提供围绕动脉和静脉线连接器周向延伸的间隙。 当消毒液循环通过消毒歧管的端口时，流体围绕连接器的外表面以及通过内部流体通道循环，从而确保连接器的完全消毒。
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公开(公告)号：US5690821A
公开(公告)日：1997-11-25
申请号：US560305
申请日：1995-11-17
申请人： Rodney S. Kenley , Dennis M. Treu , Frederick H. Peter, Jr. , Thomas M. Feldsein , Kenneth E. Pawlak
发明人： Rodney S. Kenley , Dennis M. Treu , Frederick H. Peter, Jr. , Thomas M. Feldsein , Kenneth E. Pawlak
IPC分类号： A61M1/14 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/34 , A61M1/36 , A61M39/16 , B01D17/00 , B01D17/09 , B01D61/02 , B01D61/04 , B01D61/12 , B01D61/24 , B01D61/32 , B01D65/02 , B01D65/10 , C02F1/28 , C02F1/44 , C02F1/68 , F16K17/04 , B01D61/26 , B01D61/28
CPC分类号： B01D65/102 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1649 , A61M1/165 , A61M1/1656 , A61M1/166 , A61M1/1662 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1682 , A61M1/1684 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M1/1692 , A61M1/1694 , A61M1/288 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3465 , A61M1/3468 , A61M1/3626 , A61M1/3627 , A61M1/3629 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , B01D61/02 , B01D61/025 , B01D61/04 , B01D61/12 , B01D61/32 , B01D65/022 , B01D65/104 , C02F1/441 , F16K17/0453 , A61M1/1658 , A61M2205/12 , A61M2205/15 , A61M2205/17 , A61M2205/3382 , A61M2205/3386 , A61M2205/505 , A61M2205/6072 , A61M2205/705 , A61M2205/707 , A61M2205/7554 , A61M2205/7581 , A61M2206/11 , A61M39/16 , B01D2311/04 , B01D2321/04 , B01D2321/16 , B01D2321/32 , Y10S210/929 , Y10S215/03 , Y10T137/7722 , Y10T137/7794 , Y10T137/7796 , Y10T137/7799
摘要： A loading platform and chemical addition system are described for a machine that prepares a batch of dialysate. The loading platform is in fluid communication with a dialysate preparation tank, and receives chemical vessels that contain a batch quantity of dialysate chemicals. The chemicals are released from the vessels automatically and fall onto a shelf in the loading platform. Nozzles and spray equipment are provided for insuring the complete release of the chemicals from the vessels and their dispersion into the tank. Novel mixing techniques are implemented in the tank to insure complete mixing of the dialysate solution and prevention of settling of dialysate solution at the bottom of the tank.
摘要翻译： 对于准备一批透析液的机器，描述了装载平台和化学添加系统。 装载平台与透析液制备罐流体连通，并接收含有一批透析液的化学容器。 化学品自动从容器中释放出来并落到装载平台上的搁板上。 提供喷嘴和喷雾设备，用于确保化学品从容器中完全释放并将其分散到罐中。 在罐中实施新的混合技术以确保透析液的完全混合并防止在罐底部的透析液的沉降。
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6.发明授权
公开(公告)号：US5591344A
公开(公告)日：1997-01-07
申请号：US388275
申请日：1995-02-13
申请人： Rodney S. Kenley , Dennis M. Treu , Frederick H. Peter, Jr. , Thomas M. Feldsein , Kenneth E. Pawlak , Wayne F. Adolf , Linda Roettger
发明人： Rodney S. Kenley , Dennis M. Treu , Frederick H. Peter, Jr. , Thomas M. Feldsein , Kenneth E. Pawlak , Wayne F. Adolf , Linda Roettger
IPC分类号： A61M1/14 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/34 , A61M1/36 , A61M39/16 , B01D17/00 , B01D17/09 , B01D61/02 , B01D61/04 , B01D61/12 , B01D61/24 , B01D61/32 , B01D65/02 , B01D65/10 , C02F1/28 , C02F1/44 , C02F1/68 , F16K17/04 , A61L2/00 , B01D36/00 , B01D65/00
CPC分类号： B01D65/102 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1649 , A61M1/165 , A61M1/1656 , A61M1/166 , A61M1/1662 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1682 , A61M1/1684 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M1/1692 , A61M1/1694 , A61M1/288 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3465 , A61M1/3468 , A61M1/3626 , A61M1/3627 , A61M1/3629 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , B01D61/02 , B01D61/025 , B01D61/04 , B01D61/12 , B01D61/32 , B01D65/022 , B01D65/104 , C02F1/441 , F16K17/0453 , A61M1/1658 , A61M2205/12 , A61M2205/15 , A61M2205/17 , A61M2205/3382 , A61M2205/3386 , A61M2205/505 , A61M2205/6072 , A61M2205/705 , A61M2205/707 , A61M2205/7554 , A61M2205/7581 , A61M2206/11 , A61M39/16 , B01D2311/04 , B01D2321/04 , B01D2321/16 , B01D2321/32 , Y10S210/929 , Y10S215/03 , Y10T137/7722 , Y10T137/7794 , Y10T137/7796 , Y10T137/7799
摘要： A dialysis machine is disclosed that incorporates a water treatment module, a dialysate preparation module having a dialysate circuit, and an extracorporeal circuit including a dialyzer and arterial and venous blood lines that connect to the patient. The machine accomplishes on-line disinfection of all the fluid circuits of the machine, including the water treatment module, the dialysate preparation module and extracorporeal circuit, the arterial and venous lines, and the dialyzer, by circulating water heated to a high level disinfection temperature (e.g., 80 degrees C.) through the fluid passages of the machine for a sufficient time (such as an hour) to achieve high level disinfection. After the dialysis session is ended, the patient connects the arterial and venous lines to ports in a disinfection manifold that places the arterial and venous lines into fluid communication with the heated water. Thereafter, the machine is ready to disinfect the fluid circuits including the extracorporeal circuit. In a preferred embodiment, the ports of the disinfection manifold ports include recessed features that permit the hot water to circulate on the interior and exterior surfaces of the arterial and venous line connectors, thereby insuring that the surfaces of connectors themselves are also disinfected.
摘要翻译： 公开了一种透析机，其包括水处理模块，具有透析液回路的透析液制备模块，以及包括透析器和连接到患者的动脉和静脉血液系统的体外回路。 该机器通过循环加热到高水平消毒温度的水，对机器的所有流体回路进行在线消毒，包括水处理模块，透析液制备模块和体外循环，动脉和静脉管线和透析器 （例如，80摄氏度）通过机器的流体通道足够的时间（例如一小时）以实现高水平的消毒。 在透析会话结束之后，患者将动脉和静脉线路连接到消毒歧管中的端口，其将动脉和静脉线与加热的水流体连通。 此后，机器准备对包括体外回路的流体回路进行消毒。 在优选实施例中，消毒歧管端口的端口包括允许热水在动脉和静脉线连接器的内表面和外表面上循环的凹陷特征，从而确保连接器本身的表面也被消毒。
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公开(公告)号：US5716531A
公开(公告)日：1998-02-10
申请号：US893125
申请日：1997-07-15
IPC分类号： A61M1/14 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/34 , A61M1/36 , A61M39/16 , B01D17/00 , B01D17/09 , B01D61/02 , B01D61/04 , B01D61/12 , B01D61/24 , B01D61/32 , B01D65/02 , B01D65/10 , C02F1/28 , C02F1/44 , C02F1/68 , F16K17/04
CPC分类号： B01D65/102 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1649 , A61M1/165 , A61M1/1656 , A61M1/166 , A61M1/1662 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1682 , A61M1/1684 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M1/1692 , A61M1/1694 , A61M1/288 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3465 , A61M1/3468 , A61M1/3626 , A61M1/3627 , A61M1/3629 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , B01D61/02 , B01D61/025 , B01D61/04 , B01D61/12 , B01D61/32 , B01D65/022 , B01D65/104 , C02F1/441 , F16K17/0453 , A61M1/1658 , A61M2205/12 , A61M2205/15 , A61M2205/17 , A61M2205/3382 , A61M2205/3386 , A61M2205/505 , A61M2205/6072 , A61M2205/705 , A61M2205/707 , A61M2205/7554 , A61M2205/7581 , A61M2206/11 , A61M39/16 , B01D2311/04 , B01D2321/04 , B01D2321/16 , B01D2321/32 , Y10S210/929 , Y10S215/03 , Y10T137/7722 , Y10T137/7794 , Y10T137/7796 , Y10T137/7799
摘要： A method is described for determining the sodium clearance of a dialyzer. Dialysate containing sodium ions is circulated through the dialysate side of the dialyzer. Water is continuously circulated through the blood side of the dialyzer, the water being single passed through the blood side of the dialyzer. Measurements of the conductivity of the dialysate are made prior to the dialysate entering the dialyzer, and measurements of the conductivity of the dialysate are made after the dialysate has passed through the dialyzer. The clearance of the sodium ions by the dialyzer is calculated from the measurements of conductivity. The measurements of conductivity of the dialysate after passing through the dialyzer becomes substantially constant as the dialysate and water are circulated through the dialyzer. The sodium clearance corresponds to urea clearance of the dialyzer, since the two molecules are approximately the same size.
摘要翻译： 描述了用于确定透析器的钠离子的方法。 含有钠离子的透析液通过透析器的透析液循环。 水通过透析器的血液侧连续循环，水单独通过透析器的血液侧。 在透析液进入透析器之前进行透析液的电导率的测量，并且在透析液通过透析器之后进行透析液的电导率的测量。 通过透析器的钠离子清除率由电导率的测量计算。 通过透析器后透析液的电导率的测量结果变得基本上恒定，因为透析液和水通过透析器循环。 钠离子对应于透析器的尿素清除率，因为两个分子的大小大致相同。
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公开(公告)号：US5725776A
公开(公告)日：1998-03-10
申请号：US560334
申请日：1996-03-01
IPC分类号： A61M1/14 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/34 , A61M1/36 , A61M39/16 , B01D17/00 , B01D17/09 , B01D61/02 , B01D61/04 , B01D61/12 , B01D61/24 , B01D61/32 , B01D65/02 , B01D65/10 , C02F1/28 , C02F1/44 , C02F1/68 , F16K17/04 , B01D61/34
CPC分类号： B01D65/102 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1649 , A61M1/165 , A61M1/1656 , A61M1/166 , A61M1/1662 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1682 , A61M1/1684 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M1/1692 , A61M1/1694 , A61M1/288 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3465 , A61M1/3468 , A61M1/3626 , A61M1/3627 , A61M1/3629 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , B01D61/02 , B01D61/025 , B01D61/04 , B01D61/12 , B01D61/32 , B01D65/022 , B01D65/104 , C02F1/441 , F16K17/0453 , A61M1/1658 , A61M2205/12 , A61M2205/15 , A61M2205/17 , A61M2205/3382 , A61M2205/3386 , A61M2205/505 , A61M2205/6072 , A61M2205/705 , A61M2205/707 , A61M2205/7554 , A61M2205/7581 , A61M2206/11 , A61M39/16 , B01D2311/04 , B01D2321/04 , B01D2321/16 , B01D2321/32 , Y10S210/929 , Y10S215/03 , Y10T137/7722 , Y10T137/7794 , Y10T137/7796 , Y10T137/7799
摘要： Methods and apparatus for increasing the accuracy of ultrafiltration in a dialysis machine and decreasing the time required for dialysis. The machine inclused a substantially non-compliant tank for mixing and storing a batch of dialsyate. In a preferred form, the tank is a hollow vessel made from a lightweight and chemically inert material, such as polypropylene, reinforced on its exterior. The machine further includes an ultrafiltration pump for pumping fluid from an extracorporeal circuit to an ultrafiltration tank commensurate with the removal of water from the patient. The pump is calibrated with the volume of fluid in the tank. The reduction in the time to conduct hemodialysis of the patient is achieved by introducing the patient's blood into the arterial line and conducting the blood to the blood pump, measuring the pressure of the blood in the arterial line, increasing the pump rate of the blood pump, and in the event that the pressure measured in the arterial line drops below a predetermined threshold value, slowing the pump rate of the blood pump.
摘要翻译： 用于提高透析机中超滤精度的方法和装置，并减少透析所需的时间。 该机器包含一个基本上不合格的罐，用于混合和储存一批dialsyate。 在优选的形式中，罐是由其外部加强的轻质化学惰性材料（例如聚丙烯）制成的中空容器。 该机器还包括一个超滤泵，用于将流体从体外循环泵送到与从患者中除去水相当的超滤罐。 泵用槽中的流体体积校准。 通过将患者的血液引入动脉管线并将血液导入血液泵，测量动脉血液中的血压，提高血液泵的泵送速率，实现对患者进行血液透析的时间的减少 ，并且在动脉线中测量的压力下降到预定阈值以下的情况下，减慢血液泵的泵速。
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公开(公告)号：US5702606A
公开(公告)日：1997-12-30
申请号：US560439
申请日：1995-11-17
IPC分类号： A61M1/14 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/34 , A61M1/36 , A61M39/16 , B01D17/00 , B01D17/09 , B01D61/02 , B01D61/04 , B01D61/12 , B01D61/24 , B01D61/32 , B01D65/02 , B01D65/10 , C02F1/28 , C02F1/44 , C02F1/68 , F16K17/04 , B01D61/30
CPC分类号： B01D65/102 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1649 , A61M1/165 , A61M1/1656 , A61M1/166 , A61M1/1662 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1682 , A61M1/1684 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M1/1692 , A61M1/1694 , A61M1/288 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3465 , A61M1/3468 , A61M1/3626 , A61M1/3627 , A61M1/3629 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , B01D61/02 , B01D61/025 , B01D61/04 , B01D61/12 , B01D61/32 , B01D65/022 , B01D65/104 , C02F1/441 , F16K17/0453 , A61M1/1658 , A61M2205/12 , A61M2205/15 , A61M2205/17 , A61M2205/3382 , A61M2205/3386 , A61M2205/505 , A61M2205/6072 , A61M2205/705 , A61M2205/707 , A61M2205/7554 , A61M2205/7581 , A61M2206/11 , A61M39/16 , B01D2311/04 , B01D2321/04 , B01D2321/16 , B01D2321/32 , Y10S210/929 , Y10S215/03 , Y10T137/7722 , Y10T137/7794 , Y10T137/7796 , Y10T137/7799
摘要： A method is described for priming a dialyzer placed in an extracorporeal circuit of a hemodialysis machine in situ. The method comprises the steps of substantially filling the extracorporeal circuit and the blood side of the dialyzer with fluid (such as dialysate, RO water, saline, etc.), and inducing pressure pulses in the fluid. The pressure pulses cause air bubbles from the blood side of the dialyzer to be sheared off the dialyzer membrane. The air bubbles are then conducted from the dialyzer and removed from the extracorporeal circuit. Backfiltering of fluid across the dialyzer from the dialysate circuit into the extracorporeal circuit is performed in synchrony with the pressure pulses to assist in the shearing off of air bubbles from the blood side of the dialyzer membrane.
摘要翻译： 描述了一种用于将放置在血液透析机的体外循环中的透析器原位置入的方法。 该方法包括以流体（例如透析液，RO水，盐水等）基本上填充透析器的体外回路和血液侧的步骤，并且在流体中引发压力脉冲。 压力脉冲使透析器血液侧的气泡从透析器膜上剪断。 然后将气泡从透析器传导并从体外循环中移出。 通过透析器将液体从透析液回流到体外回路中，与压力脉冲同步地进行，以帮助从透析器膜的血液侧剪切气泡。
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10.发明授权
公开(公告)号：US5863421A
公开(公告)日：1999-01-26
申请号：US929943
申请日：1997-09-15
IPC分类号： A61M1/14 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/34 , A61M1/36 , A61M39/16 , B01D17/00 , B01D17/09 , B01D61/02 , B01D61/04 , B01D61/12 , B01D61/24 , B01D61/32 , B01D65/02 , B01D65/10 , C02F1/28 , C02F1/44 , C02F1/68 , F16K17/04 , B01D61/30
CPC分类号： B01D65/102 , A61L2/04 , A61L2/18 , A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1649 , A61M1/165 , A61M1/1656 , A61M1/166 , A61M1/1662 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1682 , A61M1/1684 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M1/1692 , A61M1/1694 , A61M1/288 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3465 , A61M1/3468 , A61M1/3626 , A61M1/3627 , A61M1/3629 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , B01D61/02 , B01D61/025 , B01D61/04 , B01D61/12 , B01D61/32 , B01D65/022 , B01D65/104 , C02F1/441 , F16K17/0453 , A61M1/1658 , A61M2205/12 , A61M2205/15 , A61M2205/17 , A61M2205/3382 , A61M2205/3386 , A61M2205/505 , A61M2205/6072 , A61M2205/705 , A61M2205/707 , A61M2205/7554 , A61M2205/7581 , A61M2206/11 , A61M39/16 , B01D2311/04 , B01D2321/04 , B01D2321/16 , B01D2321/32 , Y10S210/929 , Y10S215/03 , Y10T137/7722 , Y10T137/7794 , Y10T137/7796 , Y10T137/7799
摘要： A hemodialysis machine is described that has an extracorporeal circuit that is primed automatically prior to connection of the patient to the machine. The priming is accomplished by filling the extracorporeal circuit with a priming fluid, such as a saline or dialysate solution or blood. The blood pump and clamps in the arterial and venous lines are operated by a control system in a fashion to create multiple brief pressure pulses in the priming fluid. The pressure pulses shear air bubbles present on the blood side of the dialyzer membrane off the membrane. The blood pump is then operated to clear the bubbles from the dialyzer compartment where they are removed from the priming fluid by conventional bubble trap apparatus.
摘要翻译： 描述了一种血液透析机，其具有在患者连接到机器之前自动引发的体外电路。 灌注通过用引发液体（例如盐水或透析液或血液）填充体外循环来实现。 动脉和静脉管路中的血液泵和夹钳由控制系统以在启动液中产生多个短暂的压力脉冲的方式操作。 压力脉冲将存在于透析器膜血液侧的气泡从膜上剪切出来。 然后操作血泵以从透析器室中清除气泡，其中通过常规气泡捕集装置将它们从引发液体中移出。
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