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    SENSOR AND A METHOD OF ASSEMBLING A SENSOR
    1.
    发明申请
    SENSOR AND A METHOD OF ASSEMBLING A SENSOR 有权
    传感器和组装传感器的方法

    公开(公告)号：US20110217206A1

    公开(公告)日：2011-09-08

    申请号：US13043352

    申请日：2011-03-08

    申请人： Romano HOOFMAN ,  Gerard REUVERS ,  Franciscus Petrus WIDDERSHOVEN ,  Evelyne GRIDELET ,  Marcus Henricus van KLEEF

    发明人： Romano HOOFMAN ,  Gerard REUVERS ,  Franciscus Petrus WIDDERSHOVEN ,  Evelyne GRIDELET ,  Marcus Henricus van KLEEF

    IPC分类号： G01N27/00 ,  H01H11/00

    CPC分类号： B01L3/502715 ,  B01L2200/12 ,  B01L2300/0645 ,  G01N27/3275 ,  Y10T29/49105

    摘要： “Click-assembly” methods of assembling a sensor for sensing biologically-active molecules by measuring impedance changes, are disclosed, comprising supporting a bio-sensor on a carrier, the bio-sensor comprising an electronic component having at least one micro-electrode and at least one electrical contact, functionalizing the bio-sensor by physically or chemically coupling a bio-receptor molecule to each of the at least one micro-electrode, and subsequently assembling the bio-sensor with a micro-fluidic unit by means of a clamp which clamps the bio-sensor with the micro-fluidic unit, such that in use a fluid introduced into the micro-fluidic unit is able to contact the bio-receptor and is isolated from the electrical contact. The clamp may be a spring, and the method may avoid a requirement for sealing by chemical or thermal means and thereby avoid damaging the bio-receptor. Sensors which can be assembled according to such methods are also disclosed.

    摘要翻译： 公开了通过测量阻抗变化来组装用于感测生物活性分子的传感器的“点击组装”方法，其包括在载体上支撑生物传感器，所述生物传感器包括具有至少一个微电极的电子部件和 至少一个电接触，通过将所述生物受体分子物理或化学耦合至所述至少一个微电极中的每一个来官能化所述生物传感器，以及随后通过夹具将所述生物传感器与微流体单元组装 其利用微流体单元夹持生物传感器，使得在使用中，引入微流体单元的流体能够接触生物接受体并与电接触物隔离。 夹具可以是弹簧，并且该方法可以避免通过化学或热方式对密封的要求，从而避免损坏生物受体。 还公开了可以根据这些方法组装的传感器。

    PH SENSOR AND MANUFACTURING METHOD
    3.
    发明申请
    PH SENSOR AND MANUFACTURING METHOD 有权
    PH传感器和制造方法

    公开(公告)号：US20130069120A1

    公开(公告)日：2013-03-21

    申请号：US13600385

    申请日：2012-08-31

    申请人： Matthias MERZ ,  Coenraad Cornelis TAK ,  Romano HOOFMAN

    发明人： Matthias MERZ ,  Coenraad Cornelis TAK ,  Romano HOOFMAN

    IPC分类号： G01N27/414 ,  H01L21/98

    CPC分类号： G01N27/302 ,  G01N27/4148 ,  G01N27/4167 ,  G01N33/02 ,  G01N33/04 ,  G01N33/12 ,  H01L2224/48091 ,  H01L2924/1815 ,  Y10T29/49002 ,  H01L2924/00014

    摘要： Disclosed is a pH sensor comprising a carrier (10) comprising a plurality of conductive tracks and an exposed conductive area (40) defining a reference electrode connected to one of said conductive tracks; a sensing device (30) mounted on the carrier and connected at least one other of said conductive tracks; an encapsulation (20) covering the carrier, said encapsulation comprising a first cavity (22) exposing a surface (32) of the sensing device and a second cavity (24) exposing the exposed conductive area, said second cavity comprising a reference electrode material (42) and an ion reservoir material (44) sharing at least one ion type with said reference electrode material, the reference electrode material being sandwiched between the exposed conductive area and the ion reservoir material. A method of manufacturing such a pH sensor is also disclosed.

    摘要翻译： 公开了一种pH传感器，其包括包括多个导电轨道的载体（10）和限定连接到所述导电轨道之一的参考电极的暴露导电区域（40） 感测装置（30），其安装在所述载体上并且连接至少另一个所述导电轨道; 覆盖所述载体的封装（20），所述封装包括暴露所述感测装置的表面（32）的第一空腔（22）和暴露所述暴露的导电区域的第二空腔（24），所述第二空腔包括参考电极材料 42）和与所述参考电极材料共享至少一种离子型离子储存器材料（44），所述参考电极材料夹在所述暴露的导电区域和所述离子储存器材料之间。 还公开了制造这种pH传感器的方法。